Hippocampal interneurons are abnormal in schizophrenia

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  2. Development of the MAM model of schizophrenia in mice: Sex similarities and differences of hippocampal and prefrontal cortical function
    K. Chalkiadaki, Aggeliki Velli, Evangelos Kyriazidis, Vasiliki Stavroulaki, Vasilis Vouvoutsis, E. Chatzaki, M. Aivaliotis, K. Sidiropoulou · 2019 · Neuropharmacology
  3. Targeting sleep oscillations to improve memory in schizophrenia
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  4. A Longitudinal Study of Alterations of Hippocampal Volumes and Serum BDNF Levels in Association to Atypical Antipsychotics in a Sample of First-Episode Patients with Schizophrenia
    Emmanouil N. Rizos, Matilda A. Papathanasiou, Panagiota G. Michalopoulou, Efstathios Laskos, Aggeliki Mazioti, Anastasia Kastania, Konstantina Vasilopoulou, Paraskevi Nikolaidou, Dimitrios Margaritis, Charalabos Papageorgiou et al. · 2014 · PLoS ONE
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  6. Effect of estrous cycle on schizophrenia-like behaviors in MAM exposed rats
    Stephanie M. Perez, Jennifer J. Donegan, Daniel J. Lodge · 2019 · Behavioural Brain Research
  7. ErbB4 reduces synaptic GABA A currents independent of its receptor tyrosine kinase activity
    Robert M. Mitchell, Megan J. Janssen, Irina D. Karavanova, Detlef Vullhorst, Katrina E. Furth, Anthony J. Makusky, Sanford P. Markey, Andrés Buonanno · 2013 · Proceedings of the National Academy of Sciences
  8. Homer1a protein expression in schizophrenia, bipolar disorder, and major depression
    Stefan L. Leber, Ida Cirila Llenos, Christine L. Miller, Jeannette R. Dulay, Johannes Haybaeck, Serge Weis · 2017 · Journal of Neural Transmission
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  10. Treatment with levetiracetam improves cognition in a ketamine rat model of schizophrenia
    Ming Teng Koh, Yi Shao, Sharon J. Rosenzweig-Lipson, Michela Gallagher · 2017 · Schizophrenia Research
  11. RETRACTED: Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggests Dentate Gyrus Pathology Linked to N-Methyl-D-Aspartate Receptor Hypofunction
    Nina Vanessa Kraguljac, Matthew S. Carle, Michael A. Frölich, Steve Tran, Michael A. Yassa, David Matthew White, Abhishek Reddy, Adrienne Carol Lahti · 2017 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · Retracted
  12. Molecular alterations in the medial temporal lobe in schizophrenia
    Anastasia M. Bobilev, Jessica Marie Perez, Carol A. Tamminga · 2019 · Schizophrenia Research
  13. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients
    S. Papiol, D. Keeser, A. Hasan, T. Schneider-Axmann, F. Raabe, F. Degenhardt, M. Rossner, H. Bickeböller, Ludovico Cantuti-Castelvetri, M. Simons et al. · 2019 · Translational Psychiatry
  14. Using animal models for the studies of schizophrenia and depression: The value of translational models for treatment and prevention
    Daniela L. Uliana, Xiyu Zhu, Felipe V. Gomes, Anthony A. Grace · 2022 · Frontiers in Behavioral Neuroscience
  15. Levetiracetam Attenuates Adolescent Stress-induced Behavioral and Electrophysiological Changes Associated With Schizophrenia in Adult Rats.
    A. M. Cavichioli, Thamyris Santos-Silva, A. Grace, F. Guimarães, F. V. Gomes · 2022 · Schizophrenia bulletin
  16. From Toxoplasmosis to Schizophrenia via NMDA Dysfunction: Peptide Overlap between Toxoplasma gondii and N-Methyl-d-Aspartate Receptors As a Potential Mechanistic Link
    Guglielmo Lucchese · 2017 · Frontiers in Psychiatry
  17. Using human brain imaging studies as a guide toward animal models of schizophrenia
    Scott S. Bolkan, Fernanda Carvalho Poyraz, Christoph Kellendonk · 2015 · Neuroscience
  18. Reduced GABA neuron density in auditory cerebral cortex of subjects with major depressive disorder
    John F. Smiley, Troy A. Hackett, Cynthia Bleiwas, Eva Petkova, Aleksandar Stankov, J. John Mann, Gorazd B. Rosoklija, Andrew J. Dwork · 2015 · Journal of Chemical Neuroanatomy
  19. The Hippocampus and Social Impairment in Psychiatric Disorders
    Matthew Schafer, Daniela Schiller · 2018 · Cold Spring Harbor Symposia on Quantitative Biology
  20. NMDAR hypofunction and somatostatin-expressing GABAergic interneurons and receptors: A newly identified correlation and its effects in schizophrenia
    Fatemah A. Alherz, Mohammad Alherz, Hashemiah Mohammad Almusawi · 2017 · Schizophrenia Research Cognition
  21. Chronic ketamine produces altered distribution of parvalbumin-positive cells in the hippocampus of adult rats
    Jonathan J. Sabbagh, Andrew S. Murtishaw, Monica M. Bolton, Chelcie F. Heaney, Michael A. Langhardt, Jefferson W. Kinney · 2013 · Neuroscience Letters
  22. Relationship between somatostatin and death receptor expression in the orbital frontal cortex in schizophrenia: a postmortem brain mRNA study
    Dipesh Joshi, Vibeke Sorensen Catts, Juan C Olaya, Cynthia Shannon Weickert · 2015 · Schizophrenia
  23. Regulation of neuronal survival by DNA methyltransferases
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  24. Schizophrenia-Like Phenotype Inherited by the F2 Generation of a Gestational Disruption Model of Schizophrenia
    Stephanie M. Perez, David D. Aguilar, Jennifer L. Neary, Melanie A. Carless, Andrea Giuffrida, Daniel J. Lodge · 2015 · Neuropsychopharmacology
  25. Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment
    Patrycja Klimczak, Arianna Rizzo, Esther Castillo-Gómez, Marta Pérez-Rando, Yaiza Gramuntell, M.a Carmen Salcedo Beltrán, Juan Nácher · 2021 · Frontiers in Synaptic Neuroscience
  26. Synaptic dysfunction in schizophrenia
    Emre Mısır, Guvem Gumus Akay · 2023 · Synapse
  27. Estradiol and raloxifene modulate hippocampal gamma oscillations during a spatial memory task
    Anna Schroeder, Matthew R. Hudson, Xin Du, Yee Wen Candace Wu, Jay Nakamura, Maarten van den Buuse, Nigel C. Jones, Rachel Hill · 2017 · Psychoneuroendocrinology
  28. Oxytocin modulates hippocampal perfusion in people at clinical high risk for psychosis
    Cathy Davies, Yannis Paloyelis, Grazia Rutigliano, Marco Cappucciati, Andrea De Micheli, Valentina Ramella‐Cravaro, Umberto Provenzani, Mathilde Antoniades, Gemma Modinos, Dominic Oliver et al. · 2019 · Neuropsychopharmacology
  29. Exploring causal mechanisms of psychosis risk
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  30. Decreased Oligodendrocyte Number in Hippocampal Subfield CA4 in Schizophrenia: A Replication Study
    Andrea Schmitt, Laura Tatsch, Alisa Vollhardt, Thomas Schneider-Axmann, Florian J. Raabe, Lukas Roell, Helmut Heinsen, Patrick R. Hof, Peter Falkai, Christoph Schmitz · 2022 · Cells
  31. Dorsal CA1 interneurons contribute to acute stress-induced spatial memory deficits
    Jing-Ying Yu, Ping Fang, Chi Wang, Xing-Xing Wang, Kun Li, Qian Gong, Benyan Luo, Xiaodong Wang · 2018 · Neuropharmacology
  32. Moderate prenatal alcohol exposure alters the number and function of GABAergic interneurons in the murine orbitofrontal cortex
    Johnny A. Kenton, Tiahna Ontiveros, Clark W. Bird, Carlos Fernando Valenzuela, Jonathan L. Brigman · 2020 · Alcohol
  33. Building models for postmortem abnormalities in hippocampus of schizophrenics
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  34. Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats
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  35. Hippocampal α5-GABAA Receptors Modulate Dopamine Neuron Activity in the Rat Ventral Tegmental Area
    Stephanie M. Perez, Alexandra M. McCoy, Thomas Damien Prevot, Md Yeunus Mian, Flavia Regina Carreno, Alan Frazer, James Minton Cook, Etienne L. Sibille, Daniel J. Lodge · 2022 · Biological Psychiatry Global Open Science
  36. Insights into the Mechanism of Action of Antipsychotic Drugs Derived from Animal Models: Standard of Care versus Novel Targets
    A. Grace, D. Uliana · 2023 · International Journal of Molecular Sciences
  37. The Engram’s Dark Horse: How Interneurons Regulate State-Dependent Memory Processing and Plasticity
    Frank Raven, Sara J. Aton · 2021 · Frontiers in Neural Circuits
  38. An augmented dopamine system function is present prior to puberty in the methylazoxymethanol acetate rodent model of schizophrenia
    Li Chen, Stephanie M. Perez, Daniel J. Lodge · 2014 · Developmental Neurobiology
  39. Emerging therapeutic targets for schizophrenia: a framework for novel treatment strategies for psychosis
    Susan F. Sonnenschein, Anthony A. Grace · 2020 · Expert Opinion on Therapeutic Targets
  40. How do zebrafish ( Danio rerio ) respond to MK‐801 and amphetamine? Relevance for assessing schizophrenia‐related endophenotypes in alternative model organisms
    Radharani Benvenutti, Matheus Gallas‐Lopes, Adrieli Sachett, Matheus Marcon, Nathan Ryzewski Strogulski, Carlos G. Reis, Rafael Chitolina, Ângelo Piato, Ana Paula Herrmann · 2021 · Journal of Neuroscience Research
  41. VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination
    Pushpinder Kaur Multani, Rachel Hodge, Marcel A. Estévez, Ted G. Abel, Hank F. Kung, Mark D. Alter, Bonnie L. Brookshire, Irwin Lucki, Aleksandra H. Nall, Konrad Talbot et al. · 2012 · Neuroscience
  42. Interneuron Progenitor Transplantation to Treat CNS Dysfunction
    Muhammad O. Chohan, Holly M Moore · 2016 · Frontiers in Neural Circuits
  43. Diabetes and Cognitive Deficits in Chronic Schizophrenia: A Case-Control Study
    Mei Han, Xu‐Feng Huang, Da Chun Chen, Meihong Xiu, Thomas R. Kosten, Xiang Yang Zhang · 2013 · PLoS ONE
  44. Raloxifene recovers effects of prenatal immune activation on cognitive task-induced gamma power
    Anna Schroeder, Jay Nakamura, Matthew R. Hudson, Nigel C. Jones, Xin Du, Suresh Sundram, Rachel Hill · 2019 · Psychoneuroendocrinology
  45. Tianeptine antagonizes the reduction of PV+ and GAD67 cells number in dorsal hippocampus of socially isolated rats
    Ivana Perić, Andrijana Stanisavljević, Dragoš Inta, Peter Gass, Undine Emmi Lang, Stefan Borgwardt, Dragana Filipović · 2018 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  46. What are the similarities and differences between schizophrenia and schizophrenia-like psychosis of epilepsy? A neuropathological approach to the understanding of schizophrenia spectrum and epilepsy
    Ludmyla Kandratavicius, Jaime E. C. Hallak, João Pereira Leite · 2014 · Epilepsy & Behavior
  47. Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia
    Anton Schulmann, Stefano Marenco, Marquis P. Vawter, Nirmala Akula, Agenor Limón, Ajeet Mandal, Pavan Kumar Auluck, Yash Patel, Barbara K. Lipska, Francis J. McMahon · 2023 · Translational Psychiatry
  48. Bipolar disorders and schizophrenia: discrete disorders?
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  49. The mGluR2/3 agonist pomaglumetad methionil normalizes aberrant dopamine neuron activity via action in the ventral hippocampus
    Susan F. Sonnenschein, Anthony A. Grace · 2020 · Neuropsychopharmacology
  50. Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle
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  51. Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder
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  52. Enriched Environment Reverts Somatostatin Interneuron Loss in MK-801 Model of Schizophrenia
    Ane Murueta‐Goyena, Naiara Ortuzar, José Vicente Lafuente, Harkaitz Bengoetxea · 2019 · Molecular Neurobiology
  53. A Role for the Transcription Factor Nk2 Homeobox 1 in Schizophrenia: Convergent Evidence from Animal and Human Studies
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  54. Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia
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  55. Cell-based therapies for the treatment of schizophrenia
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  56. Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice
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  57. Na+, K+-ATPase α3 isoform in frontal cortex GABAergic neurons in psychiatric diseases
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  58. Normative modelling of molecular-based functional circuits captures clinical heterogeneity transdiagnostically in psychiatric patients
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  59. Prenatal alcohol and cannabis exposure can have opposing and region‐specific effects on parvalbumin interneuron numbers in the hippocampus
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  60. Nicotinic Receptors and Functional Regulation of GABA Cell Microcircuitry in Bipolar Disorder and Schizophrenia
    Francine Mary Benes · 2012 · Handbook of experimental pharmacology
  61. Relational memory and hippocampal function in psychotic bipolar disorder
    Suzanne N. Avery, Lisa E. Williams, Austin A. Woolard, Stephan Heckers · 2013 · European Archives of Psychiatry and Clinical Neuroscience
  62. Calretinin and parvalbumin in schizophrenia and affective disorders: a mini-review, a perspective on the evolutionary role of calretinin in schizophrenia, and a preliminary post-mortem study of calretinin in the septal nuclei
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  64. Degradation of Perineuronal Nets in the Ventral Hippocampus of Adult Rats Recreates an Adolescent-Like Phenotype of Stress Susceptibility
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  65. Peripubertal mGluR2/3 Agonist Treatment Prevents Hippocampal Dysfunction and Dopamine System Hyperactivity in Adulthood in MAM Model of Schizophrenia.
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  67. Colocalization of cannabinoid receptor 1 with somatostatin and neuronal nitric oxide synthase in rat brain hippocampus
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  74. Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone
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  75. Animal Models of Developmental Neuropathology in Schizophrenia
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