Hippocampal interneurons are abnormal in schizophrenia
Konradi, Christine, Yang, C. Kevin, Zimmerman, Eric I., Lohmann, Kathryn M., Gresch, Paul, Pantazopoulos, Harry, Berretta, Sabina, Heckers, Stephan·2011·Schizophrenia Research
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- Schizophrenia, Other Neuropsychiatric Disorders, and SleepDara S. Manoach, Ann K. Shinn, Robert Stickgold · 2013 · Elsevier eBooks
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- Assessing a Two-Hit Model of Schizophrenia: Prenatal choline deficiency and induced hypofunction of NMDA receptors in male and female Long Evans ratsSamuel W Gray · 2020 · Digital Commons - Colby (Colby College)
- Schizophrenia: Current Hypotheses, Treatments, and Future DirectionsJake A. Aadland · 2020 · Figshare
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