Hippocampal interneurons are abnormal in schizophrenia

Cited by (287)

Items 201–287 of 287

  1. Neurocognition and NMDAR co-agonists pathways in individuals with treatment resistant first-episode psychosis: a 3-year follow-up longitudinal study
    Sara Camporesi, Lijing Xin, Philippe Golay, Chin B. Eap, Martine Cleusix, Michel Cuénod, Margot Fournier, Kenji Hashimoto, Raoul Jenni, Julie Ramain et al. · 2024 · Molecular Psychiatry
  2. Glycine attenuates impairments of stimulus-evoked gamma oscillations in the ketamine model of schizophrenia
    Moritz Haaf, Stjepan Ćurić, Saskia Steinmann, Jonas Rauh, Gregor Leicht, Christoph Mulert · 2022 · NeuroImage
  3. Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia
    Moritz Haaf, Stjepan Ćurić, Jonas Rauh, Saskia Steinmann, Christoph Mulert, Gregor Leicht · 2023 · International Journal of Molecular Sciences
  4. Excitatory and inhibitory neuron imbalance in the intrauterine growth restricted fetal guinea pig brain: Relevance to the developmental origins of schizophrenia and autism
    Angela L. Cumberland, Nadia Hale, Aminath Azhan, Courtney P. Gilchrist, Ginevra Chincarini, Mary Tolcos · 2022 · Developmental Neurobiology
  5. Effects of diazepam on hippocampal blood flow in people at clinical high risk for psychosis
    Nicholas R Livingston, Amanda Kiemes, Gabriel A. Devenyi, Samuel Knight, Paulina B. Lukow, Luke A. Jelen, Thomas James Reilly, Aikaterini Dima, Maria Antonietta Nettis, Cecilia Casetta et al. · 2024 · Neuropsychopharmacology
  6. Disrupted hippocampal synchrony following maternal immune activation in a rat model
    Robert G.K. Munn, Amy R. Wolff, Lucinda J. Speers, David K. Bilkey · 2023 · Hippocampus
  7. Excitatory and inhibitory imbalances in the trisynaptic pathway in the hippocampus in schizophrenia: a postmortem ultrastructural study
    Charlene B. Farmer, Erica L. Roach, Lily R. Bice, Madeleine E. Falgout, Kattia G. Mata, Joy K. Roche, Rosalinda C. Roberts · 2023 · Journal of Neural Transmission
  8. Parvalbumin-positive GABAergic interneurons deficit in the hippocampus in Gunn rats: A possible hyperbilirubinemia-induced animal model of schizophrenia
    Maiko Hayashida, Tsuyoshi Miyaoka, Keiko Tsuchie, Tomoko Araki, Muneto Izuhara, Shoko Miura, Misako Kanayama, Koji Ohtsuki, Michiharu Nagahama, Ilhamuddin Abdul Azis et al. · 2019 · Heliyon
  9. A Peptide Link Between Human Cytomegalovirus Infection, Neuronal Migration, and Psychosis
    Guglielmo Lucchese, Agnes Flöel, Benjamin Stahl · 2020 · Frontiers in Psychiatry
  10. The cortical silent period in schizophrenia: A systematic review and meta-analysis focusing on disease stage and antipsychotic medication
    Atsuhiro Miyazawa, Nobuhisa Kanahara, Yuki Shiko, Yoshihito Ozawa, Yohei Kawasaki, Hiroshi Komatsu, Yuto Masumo, Yusuke Nakata, Masaomi Iyo · 2022 · Journal of Psychopharmacology
  11. Gestational Methylazoxymethanol Acetate Administration Alters Proteomic and Metabolomic Markers of Hippocampal Glutamatergic Transmission
    Daniel J. Lodge, Anthony A. Grace · 2011 · Neuropsychopharmacology
  12. Acute systemic MK‐801 induced functional uncoupling between hippocampal areas CA3 and CA1 with distant effect in the retrosplenial cortex
    Helena Buchtová, Iveta Fajnerová, Aleš Stuchlı́k, Štěpán Kubík · 2016 · Hippocampus
  13. Automated SPE and nanoLC–MS analysis of somatostatin
    Gábor Maász, János Schmidt, Péter Avar, László Márk · 2017 · Journal of Liquid Chromatography & Related Technologies
  14. Aberrant Dopamine System Function in the Ferrous Amyloid Buthionine (FAB) Rat Model of Alzheimer’s Disease
    Stephanie M. Perez, Angela M. Boley, Alexandra M. McCoy, Daniel J. Lodge · 2023 · International Journal of Molecular Sciences
  15. Alterations of the IKZF1-IKZF2 tandem in immune cells of schizophrenia patients regulate associated phenotypes
    Iván Ballasch, Laura López-Molina, Marcos Galán-Ganga, Anna Sancho‐Balsells, Irene Rodríguez-Navarro, Sara Borràs‐Pernas, M. Angeles Rabadán, Wanqi Chen, Carlota Pastó-Pellicer, Francesca Flotta et al. · 2024 · Journal of Neuroinflammation
  16. Rethinking parvalbumin: From passive marker to active modulator of hippocampal circuits
    Na Zhang, Bin Hu, Xiaoming Li, Huiqian Huang · 2025 · IBRO Neuroscience Reports
  17. Diminished serum repetin levels in patients with schizophrenia and bipolar disorder
    Shuai Wang, Huixun Ren, Jie Xu, Yanjun Yu, Shui‐Ping Han, Hui Qiao, Shaoli Cheng, Chang Shui Xu, Shu-Cheng An, Bomiao Ju et al. · 2015 · Scientific Reports
  18. Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
    Brian R. Christie, Allyson Gross, Annika Willoughby, Erin L. Gräfe, Justin Brand, Emily Bosdachin, Hannah M. O. Reid, Crystal Acosta, Eric Eyolfson · 2023 · Journal of Visualized Experiments
  19. A genome-wide association study of early gamma-band response in a schizophrenia case–control sample
    Bettina Konte, Gregor Leicht, Ina Giegling, Oliver Michael Pogarell, Susanne Karch, Annette M. Hartmann, Marion Friedl, Ulrich Hegerl, Dan Rujescu, Christoph Mulert · 2017 · The World Journal of Biological Psychiatry
  20. Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia
    Darren Cameron, Ngoc‐Nga Vinh, Parinda Prapaiwongs, Elizabeth A Perry, James Walters, Meng Li, Michael C. O’Donovan, Nicholas J. Bray · 2024 · Schizophrenia Bulletin
  21. Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD67, and PPAR-γ
    Talita Rodrigues, Getúlio Nicola Bressan, Bárbara Nunes Krum, Félix Alexandre Antunes Soares, Roselei Fachinetto · 2023 · Pharmacology Biochemistry and Behavior
  22. Molecular diversity and lineage commitment of human interneuron progenitors
    Dmitry Velmeshev, Manideep Chavali, Tomasz Jan Nowakowski, Mohini Bhade, Simone Mayer, Nitasha Goyal, Beatriz Alvarado, Walter Mancia, Shaohui Wang, Matthew L Speir et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Prenatal Exposure to MAM Impairs mPFC and Hippocampal Inhibitory Function in Mice during Adolescence and Adulthood
    Zhiyin He, Qian He, Xiao-Rong Tang, Keni Huang, Yi-Wen Lin, Jian-Rui Xu, Qi-Liang Chen, Neng-Gui Xu, Lulu Yao · 2024 · eNeuro
  24. Protective Effects of N-Acetylcysteine Against Schizophrenia-Related Behavioral and Parvalbumin Interneuron Deficits Induced by Adolescent Stress
    Icaro da Silva Freitas, Francisco Silveira Guimarães, Felipe V. Gomes · 2025 · Schizophrenia Bulletin Open
  25. GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study
    Paulina B. Lukow, Julia J. Schubert, Mario Severino, Samuel Knight, Amanda Kiemes, Nicholas R Livingston, James Davies, Andrea De Micheli, Thomas J. Spencer, Paolo Fusar‐Poli et al. · 2025 · Molecular Psychiatry
  26. Impaired homeostatic regulation of feedback inhibition associated with system deficiency to detect fluctuation in stimulus intensity: a simulation study
    Faramarz Faghihi, Ahmed A. Moustafa · 2014 · Neurocomputing
  27. Oxytocin in Prevention of Schizophrenia
    Arman Tadjibaev · 2013 · International Journal of Prevention and Treatment of Substance Use Disorders
  28. Gamma-band entrainment abnormalities in schizophrenia: Modality-specific or cortex-wide impairment?
    Molly A. Erickson, Javier López‐Calderón, Benjamin M. Robinson, James M. Gold, Steven J. Luck · 2022 · Journal of Psychopathology and Clinical Science
  29. Blockade of the dopaminergic neurotransmission with AMPT and reserpine induces a differential expression of genes of the dopaminergic phenotype in substantia nigra
    Sergio Ortiz-Padilla, Elier Soto-Orduño, Marisa Escobar Barrios, Abril Armenta Manjarrez, Yadira Bastián, José Alfredo Tirado Méndez · 2019 · Neuropharmacology
  30. Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction
    Elizaveta A. Olkhova, Laura A. Smith, Bethany H. Dennis, Yi Shiau Ng, Fiona E. N. LeBeau, Gráinne S. Gorman · 2024 · Biochemical Society Transactions
  31. ROI-based analysis of diffusion indices in healthy subjects and subjects with deficit or non-deficit syndrome schizophrenia
    Yaşar Türk, İsmaıl Devecıoğlu, Atakan Küskün, Cem Öge, Elmas Beyazyüz, Yakup Albayrak · 2023 · Psychiatry Research Neuroimaging
  32. Sex Differences in the Ventral Subiculum's Microcircuitry and Function
    Carley N. Miller, Jason N. Aoto · 2025 · Hippocampus
  33. Hippocampal Network Dysfunction in Early Psychosis: A 2-Year Longitudinal Study
    Suzanne N. Avery, Baxter P. Rogers, Maureen McHugo, Kristan Armstrong, Jennifer Urbano Blackford, Simon Vandekar, Neil D. Woodward, Stephan Heckers · 2022 · Biological Psychiatry Global Open Science
  34. Epigenetic Dysregulation in the Schizophrenic Brain
    Tobias B. Halene, Cyril Jayakumar Peter, Schahram Akbarian · 2014 · Current Behavioral Neuroscience Reports
  35. Neurotoxic Vulnerability Underlying Schizophrenia Spectrum Disorders
    Trevor Archer, Ulla Karilampi, Serafino Ricci, Max Rapp‐Ricciardi · 2014 · Springer eBooks
  36. EFFECT OF DIABETES AND SCHIZOPHRENIA ON COGNITIVE FUNCTION IN EGYPTIANS
    Khaled M. Hadhoud, Amira Ahmed Fouad · 2013 · Zagazig University Medical Journal
  37. Cellular and molecular signatures of in vivo GABAergic neurotransmission in the human brain
    Paulina B. Lukow, Daniel Martins, Mattia Veronese, AC Vernon, Philip K. McGuire, Federico Turkheimer, Gemma Modinos · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors
    Mohammad M. Khan, Vinay Parikh · 2022 · CNS & Neurological Disorders - Drug Targets
  39. Animal Model Reveals Mechanism of Hippocampal Hyperactivity in Psychosis
    Stephan Heckers, Christine L. Konradi · 2023 · Schizophrenia Bulletin
  40. A genetic algorithm for self-supervised models of oscillatory neurodynamics
    Hamed Nejat, Jason S. Sherfey, André M. Bastos · 2026 · PLoS ONE
  41. Collecting, storing, and mining research data in a brain bank
    Maree J. Webster, Sanghyeon Kim · 2018 · Handbook of clinical neurology
  42. Cellular and Circuit Models of Increased Resting State Network Gamma Activity in Schizophrenia
    Rachel S. White, Steven J. Siegel · 2016 · Elsevier eBooks
  43. Knockdown of Lhx6 during embryonic development results in neurophysiological alterations and behavioral deficits analogous to schizophrenia in adult rats
    Hannah B. Elam, Stephanie M. Perez, Jennifer J. Donegan, Nicole E. Eassa, Daniel J. Lodge · 2024 · Schizophrenia Research
  44. Time Windows of Interneuron Development: Implications to Our Understanding of the Aetiology and Treatment of Schizophrenia
    Zarina Greenberg, Hayley S. Ramshaw, Quenten Schwarz · 2015 · AIMS neuroscience
  45. Normative Modelling of Molecular-based Functional Neurocircuits Captures Clinical Heterogeneity Transdiagnostically in Neuropsychiatric Patients
    Timothy Lawn, Alessio Giacomel, Daniel Martins, Mattia Veronese, Matthew A. Howard, Federico Turkheimer, Ottavia Dipasquale · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  46. GABAergic interneuron pathology in schizophrenia: a systematic review and meta-analysis across cell-types, brain areas, and cortical layers
    Aidan G. Mulvey, Kaitlyn M. Gabhart, Tineke Grent-‘t-Jong, Suzana Herculano‐Houzel, Peter J. Uhlhaas, André M. Bastos · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Ketamine impairs the performance of male mice in novel recognition object test and reduces the immunoreactivity of GAD67 in the hippocampus: Role of pioglitazone
    Talita Rodrigues, Getúlio Nicola Bressan, Patrícia Zorzi Juliani, Maria Eduarda Brandli da Silva, Roselei Fachinetto · 2024 · Pharmacology Biochemistry and Behavior
  48. Sleep deprivation following hippocampus-dependent learning downscales synaptic inputs to lateral and medial entorhinal cortex interneurons
    Vinodh Balendran, Jiyang Liu, Katelin Wu, Alvin Dong, Sara J. Aton · 2026 · SLEEP
  49. Antipsychotic Drug Action, Novel Treatment Targets, and the Failure of Current Clinical Trial Designs in Evaluating New Target Molecules
    Anthony A. Grace, Daniela L. Uliana · 2026 · Biological Psychiatry
  50. Knock-in mouse models for studying somatostatin and cholecystokinin expressing cells
    Marta Balog, Allison C. Anderson, Channabasavaiah B. Gurumurthy, Rolen M. Quadros, Željka Korade, Károly Mirnics · 2022 · Journal of Neuroscience Methods
  51. Neuron collinearity differentiates human hippocampal subregions: a validated deep learning approach
    Jan Oltmer, Emily M. Williams, Stefan Groha, Emma W. Rosenblum, Jessica Roy, Josué Llamas Rodríguez, Valentina Perosa, Samantha N. Champion, Matthew P. Frosch, Jean C. Augustinack · 2024 · Brain Communications
  52. Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia
    Yi‐Chen Wang, Yi-Yun Huang, E Er-Deng, Chu-Xian Fu, Jiawen Li, Yue Mi, Ning Zhong, Chaoho Ouyang, Ting Zhang, Limin Xu et al. · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  53. Schizophrenia, Other Neuropsychiatric Disorders, and Sleep
    Dara S. Manoach, Ann K. Shinn, Robert Stickgold · 2013 · Elsevier eBooks
  54. Erbb4 deletion from fast-spiking interneurons causes psychosis-relevant neuroimaging phenotypes
    Amanda Kiemes, Maria Elisa Serrano Navacerrada, Eugene Kim, Karen Randall, Camilla Simmons, Loreto Rojo Gonzalez, Marija M. Petrinovic, David J. Lythgoe, Diana Rotaru, Davide Di Censo et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  55. A cell-based NRG1-ERBB4 assay designed for high-throughput compound screening to identify small molecule modulators with relevance for schizophrenia
    Wilko Hinrichs · 2012 · eDiss (Georg-August-Universität Göttingen)
  56. Evaluation of novel dual-hit models of 'schizophrenia-like' symptoms in the rat
    Philip L. R. Gaskin · 2014 · UPT. Syiah Kuala University Library (Syiah Kuala University)
  57. Hiperactivacion cortical y deterioro cognitivo en esquizofrenia
    Suazo Bonnelly, Johanna Vanessa · 2014 · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
  58. Bipolar disorder and cognitive functioning : a two-year naturalistic study
    Baer M.G. Arts · 2012 · Research Publications (Maastricht University)
  59. CIRCUIT DYNAMICS UNDERLYING CONTROL OF DOPAMINE NEURON ACTIVITY BY THE NUCLEUS REUNIENS OF THE MIDLINE THALAMUS
    Eric I. Zimmerman · 2017 · D-Scholarship@Pitt (University of Pittsburgh)
  60. Development of the MAM model of schizophrenia in mice: Sex similarities and differences of hippocampal and prefrontal cortical function
    K. Chalkiadaki, Aggeliki Velli, Evangelos Kyriazidis, V. Stavroulaki, Vasilis Vouvoutsis, E. Chatzaki, M. Aivaliotis, K. Sidiropoulou · 2018 · bioRxiv
  61. Parvalbumin阳性中间神经元缺陷在精神分裂症病理机制中的作用
    Xiaofei Deng, Jian‐You Guo · 2018 · Advances in Psychological Science
  62. The Role of Interneurons in Cognitive Impairment in Schizophrenia
    Ane Murueta‐Goyena, José Vicente Lafuente, Harkaitz Bengoetxea Odriozola · 2018 · Springer eBooks
  63. Aberrant chloride homeostasis and inhibitory synaptic transmission in Huntington's disease
    Zahra Dargaei · 2018 · TSpace (University of Toronto)
  64. Assessing a Two-Hit Model of Schizophrenia: Prenatal choline deficiency and induced hypofunction of NMDA receptors in male and female Long Evans rats
    Samuel W Gray · 2020 · Digital Commons - Colby (Colby College)
  65. Schizophrenia: Current Hypotheses, Treatments, and Future Directions
    Jake A. Aadland · 2020 · Figshare
  66. ETHANOL SUSTAINS PHOSPHORYLATED TAU PROTEIN IMMUNOFLUORESCENCE IN THE CULTURED NEONATAL RAT HIPPOCAMPUS
    Caleb S. Bailey · 2020 · UKnowledge (University of Kentucky)
  67. The Amygdala, Hippocampus, Fornix and Nucleus Basalis
    Matthew Roy Williams · 2021 · Springer eBooks
  68. Development of a Novel Mouse Model of Psychiatric Disorders with Decreased Glucose Logistics and Related Findings
    Shinobu Hirai · 2021 · The Brain & Neural Networks
  69. Efeitos do levetiracetam sobre as alterações comportamentais e eletrofisiológicas tipo-esquizofrenia induzidas pela exposição ao estresse na adolescência
    Andreza Manzato Cavichioli · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  70. Schizophrenia, other neuropsychiatric disorders and sleep
    Dara S. Manoach, Olivia Larson, Robert Stickgold · 2021 · Elsevier eBooks
  71. Knock-in mouse models for studying somatostatin and cholecystokinin expressing cells
    Károly Mirnics, Allison Anderson, Marta Balog, Channabasavaiah B. Gurumurthy, Rolen M. Quadros, Željka Korade · 2022 · Research Square
  72. Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and rescue by risperidone
    Cristina Delgado-Sallent, Thomas Gener, Pau Nebot, Cristina López-Cabezón, Maria Victoria Puig · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  73. SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration
    Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Anne‐Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A. Anderzhanova, Fiona Tang, Galen Missig et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  74. Estudo da reabertura do período sensível de suscetibilidade ao estresse pela degradação das redes perineuronais
    Débora Akemi Endo Colodete · 2023 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  75. GABA A receptor availability in clinical high-risk and first-episode psychosis: a [ 11 C]Ro15-4513 positron emission tomography study
    Paulina B. Lukow, Julia J. Schubert, Mario Severino, Samuel Knight, Amanda Kiemes, Nicholas R Livingston, James Davies, Andrea De Micheli, Thomas J. Spencer, Paolo Fusar‐Poli et al. · 2025 · medRxiv
  76. Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of de novo lipogenesis and treatment perspectives
    Mohammad M. Khan, Zaw Ali Khan, Mohsin Ali Khan, Gauri Pandey · 2025 · World Journal of Stem Cells
  77. Erythrocyte membrane nervonic acid in drug-naive first-episode psychosis and chronic medicated schizophrenia: Implication for impaired myelination and prognosis
    Mohammad M. Khan · 2025 · World Journal of Psychiatry
  78. Diazepam modulates anterior cingulate glutamate levels in people at clinical high-risk for psychosis
    Amanda Kiemes, Nicholas R Livingston, Paulina B. Lukow, Samuel Knight, Luke A. Jelen, Thomas James Reilly, Aikaterini Dima, Maria Antonietta Nettis, David J. Lythgoe, Cecilia Casetta et al. · 2025 · The International Journal of Neuropsychopharmacology
  79. Additional file 1 of Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia
    Tertia D. Purves-Tyson, Amelia M. Brown, Christin Weissleder, Debora A. Rothmond, Cynthia Shannon-Weickert · 2021 · Figshare
  80. Selective Lis1 inactivation disrupts migration and positioning of cortical somatostatin interneurons
    Ana Pombero, R. García-López, Emilio Geijo‐Barrientos, Salvador Martı́nez · 2026 · Scientific Reports
  81. L’hypothèse freudienne du délire comme "tentative de guérison" dans la psychose : enjeux interdisciplinaires, épistémologiques et cliniques entre psychanalyse et neurosciences
    Jessica Tran The · 2019 · theses.fr (ABES)
  82. Role of early-life stress and metabotropic glutamate receptors in the developmental trajectory of the central nervous system
    Rémy Verhaeghe · 2020 · theses.fr (ABES)
  83. Somatostatin regulation of the stress response
    Hongling Guo, Tahir Ali, Shupeng Li · 2026 · Brain medicine :
  84. Somatostatin: A crossroad between pancreatic and neural pathways
    Mohammad Rahmanian, Sana Esamaeilzadeh Gharajeh, Amiryousef Zahedi, Hossein Gharedaghi, Hana Abbasian, Mahsa Kamali · 2026 · Elsevier eBooks
  85. Targeting α5-GABAA receptors to restore dopamine system function in a translationally relevant model of perimenopausal psychosis
    Kayla Lilly, Dishary Sharmin, James Minton Cook, Daniel J. Lodge, Stephanie M. Perez · 2026 · Psychopharmacology
  86. The effect of Neuregulin 1 on PCP induced alterations of locomotion, neurotransmission and cell growth as relevant for schizophrenia
    Martin Engel · 2014 · Research Online (University of Wollongong)
  87. The Impact of Oxidative Stress on GAD67 Levels and Parvalbumin-Positive Neurons
    Jessica Deslauriers, Sylvain Grignon · 2014 · Oxidative stress in applied basic research and clinical practice