Cited by 133Toxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicalsEnvironmental Toxicology and Ecotoxicology

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Carcinogenic polycyclic aromatic hydrocarbons in umbilical cord blood of human neonates from Guiyu, China

Guo, Yongyong, Huo, Xia, Wu, Kusheng, Liu, Junxiao, Zhang, Yuling, Xu, Xijin·2012·Science of The Total Environment

Abstract

Unregulated electronic-waste recycling results in serious environmental pollution of polycyclic aromatic hydrocarbons (PAHs) in Guiyu, China. We evaluated the body burden of seven carcinogenic PAHs and potential health risks for neonates. Umbilical cord blood (UCB) samples were collected from Guiyu (n=103), and the control area of Chaonan (n=80), China. PAHs in UCB were determined by gas chromatography/mass spectrometry. The median ∑7c-PAH concentration was 108.05 ppb in UCB samples from Guiyu, vs. 79.36 ppb in samples from Chaonan. Residence in Guiyu and longer cooking time of food during the gestation period were significant factors contributing to the ∑7c-PAH level. Benzo[a]anthracene (BaA), chrysene (Chr), and benzo[a]pyrene (BaP) were found to correlate with reduced neonatal height and gestational age. Infants experiencing adverse birth outcomes, on the whole, displayed higher BaA, Chr, and BaP levels compared to those with normal outcomes. We conclude that maternal PAH exposure results in fetal accumulation of toxic PAHs, and that such prenatal exposure correlates with adverse effects on neonatal health.

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Crossref · 10.1016/j.scitotenv.2012.04.007

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Research works printed but not linked: 2

  1. Fan R. Preliminary study of urinary PAHs metabolites for students in Pearl River Delta and occupational population in Guiyu-an electronic waste recycling site. Doctoral dissertation, Guangzhou: Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, 2007.
  2. IARC, 1984, Monographs programme on the evaluation of the carcinogenic risk of chemicals to humans: polynuclear aromatic compounds, IARC Monogr Eval Carcinog Risks Hum, 34, 101

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Metadata

Authors
Guo, Y., Huo, X., Wu, K., Liu, J., Zhang, Y., & Xu, X.
Affiliations
Shantou University (CN)
Corresponding author
Xu, Xijin
Venue
Science of The Total Environment
Publisher
Elsevier BV
Published
2012-06
Volume
427-428
Pages
35-40
ISSN
0048-9697 (ISSN-L)
OpenAlex
W2020554241
Cited by
133
References
43
Citations by year
2026: 9 · 2025: 5 · 2024: 9 · 2023: 8 · 2022: 11 · 2021: 16 · 2020: 9 · 2019: 9 · 2018: 10 · 2017: 11 · 2016: 10 · 2015: 6 · 2014: 8 · 2013: 12
FWCI
5.77
Type
journal article
Language
en
Open access
closed
Locations
  • The Science of The Total Environment (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Natural Science Foundation of China
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Keywords
polycyclic aromatic hydrocarbons, umbilical cord blood, neonates, Guiyu, e-waste recycling, benzo[a]pyrene, benz[a]anthracene, chrysene, birth outcomes, gestational age, environmental pollution
MeSH terms
Adult, China, Environmental Exposure, Environmental Pollutants, Female, Fetal Blood, Humans, Infant, Newborn, Male, Polycyclic Aromatic Hydrocarbons, Pregnancy, Maternal Exposure, Young Adult, Electronic Waste

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