Effects of indoor air quality and home environmental characteristics on allergic diseases among preschool children in the Greater Taipei Area
Abstract
Indoor air quality and home environmental characteristics are potential factors associated with the onset and exacerbation of allergic diseases. Our study examined the effects of these factors on allergic diseases (i.e., asthma, allergic rhinitis, allergic conjunctivitis, and atopic dermatitis) among preschool children. We recruited a total of 120 preschool children from an ongoing birth cohort study in the Greater Taipei Area. A comprehensive environmental evaluation was conducted at each participant's residence and included measurements of indoor and outdoor air pollutants, fungal spores, endotoxins, and house dust mite allergens. A structured questionnaire was used to collect information on the allergic diseases and home environments of participants. Land-use characteristics and points of interest in the surrounding area of each home were analyzed. Other covariates were obtained from the cohort data. Multiple logistic regressions were used to examine the relationships between allergic diseases and covariates. We observed that all mean indoor air pollutant levels were below Taiwan's indoor air quality standards. After adjustment for covariates, the total number of fungal spores and the ozone, Der f 1, and endotoxin levels were significantly associated with increased risks of allergic diseases. Biological contaminants more significantly affected allergic diseases than other pollutants. Moreover, home environmental characteristics (e.g., living near power facilities and gas s…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Studies showed a higher association between atopic dermatitis and air pollutants in children.
“Studies showed a higher association between AD and air pollutants in children [33, 42, 49, 58].”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [58]
Huang et al. and Chao et al. did not find any significant associations between urticaria and air pollution.
“In contrast, Huang et al. [58], and Chao et al. [29] did not find any significant associations between urticaria and AP (ESM).”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [58]
Huang et al. reported an increase in hyperpigmentation with increases in PM10 and PM2.5 levels by 0.15% and 0.16% (p < 0.01), respectively, in Taiwan.
“the study by Huang et al. [58] reported an increase in hyperpigmentation with increases in PM10 and PM2.5 levels by 0.15% and 0.16% (p < 0.01), respectively, in Taiwan.”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [58]
No significant interaction effects were observed among sociodemographic factors and air pollution.
“No significant interaction effects were observed among sociodemographic factors and AP [58].”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [58]
Cites
Rhinitis and onset of asthma: a longitudinal population-based study
Shaaban, R., Zureik, M., Soussan, D., Neukirch, C., Heinrich, J., Sunyer, J., Wjst, M., Cerveri, I., Pin, I., Bousquet, J., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61446-4 · Cited by 610 · see citing works
Association of low-level ozone and fine particles with respiratory symptoms in children with asthma
Gent, J. F. (2003) · JAMA · doi:10.1001/jama.290.14.1859 · Cited by 477 · see citing works
The Effects of Air Pollution on the Development of Atopic Disease
Hassoun, Y., James, C., & Bernstein, D. I. (2019) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-019-08730-3 · Cited by 95 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence
Singh, N., Schikowski, T., & Krutmann, J. (2026) · American Journal of Clinical Dermatology · doi:10.1007/s40257-026-01006-5 · Cited by 4 · see citing works
“No significant interaction effects were observed among sociodemographic factors and AP [58].”
Influential
- Authors
- Huang, H.-C., Zou, M.-L., Chen, Y.-H., Jiang, C.-B., Wu, C.-D., Lung, S.-C. C., Chien, L.-C., Lo, Y.-C., & Chao, H. J.
- Affiliations
- Taipei Medical University (TW)
- Mackay Medical University (TW)
- National Chung Hsing University (TW)
- Research Center for Environmental Changes, Academia Sinica (TW)
- Corresponding author
- Chao, Hsing Jasmine
- ORCID
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2023-11
- Volume
- 897
- Pages
- 165392
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W4383532769
- Cited by
- 26
- References
- 3
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 4
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Science of The Total Environment (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education (DP2-108-21121-01-N-12-03, DP2-109-21121-01-N-05-03, DP2-110-21121-01-N-05-03)
- Taiwan Ministry of Science and Technology
- Ministry of Science and Technology, Taiwan (MOST 105-2119-M-038-005)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Keywords
- indoor air quality, allergic diseases, preschool children, asthma, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, fungal spores, endotoxin, house dust mite allergens, Der f 1, ozone, land use characteristics, proximity to pollution sources, household sanitation, biological contaminants
- MeSH terms
- Air Pollutants, Asthma, Child, Preschool, Environmental Pollutants, Humans, Cohort Studies, Air Pollution, Indoor, Rhinitis, Allergic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
