The DOI matches its Crossref record; 242 of the 244 references it cites were found in a registry or an index.
Fibromyalgia and Overlapping Disorders: The Unifying Concept of Central Sensitivity Syndromes
Abstract
Objectives To discuss fibromyalgia syndrome (FMS) and overlapping conditions, eg, irritable bowel syndrome, headaches, and chronic fatigue syndrome, within the concept of central sensitivity syndromes (CSS).Methods A critical overview of the literature and incorporation of the author's own views.Results The concept of CSS seems viable. It is based on mutual associations among the CSS conditions as well as the evidence for central sensitization (CS) among several CSS members. However, such evidence is weak or not available in other members at this time, requiring further studies. The biology of CSS is based on neuroendocrine aberrations, including CS, that interact with psychosocial factors to cause a number of symptoms.Conclusions CSS is an important new concept that embraces the biopsychosocial model of disease. Further critical studies are warranted to fully test this concept. However, it seems to have important significance for new directions for research and patient care involving physician and patient education. Each patient, irrespective of diagnosis, should be treated as an individual considering both the biological and psychosocial contributions to his or her symptoms and suffering.
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“According to the classification developed by M. B. Yunus on central sensitization syndromes (2007; 2009; 2015), those that involve the experience of chronic pain could be considered as CPSS [9,10,11].”
From Effectiveness of acceptance and commitment therapy in central pain sensitization syndromes: A systematic review (2021) · cites this paper as [10]
In the citing paper
“Against this background, the similarity in widespread hypersensitivity between IBS patients and CPCS, such as FMS, led to the view that IBS is another CCS [10,11].”
From Effectiveness of acceptance and commitment therapy in central pain sensitization syndromes: A systematic review (2021) · cites this paper as [10]
In the citing paper
“Although it is not clear how these physiologic alterations are generated, there is a wide agreement that FMS should be considered as a CPSS [9,10,11,32,33,34].”
From Effectiveness of acceptance and commitment therapy in central pain sensitization syndromes: A systematic review (2021) · cites this paper as [10]
Citations
Cites
The american college of rheumatology 1990 criteria for the classification of fibromyalgia
Wolfe, F., Smythe, H. A., Yunus, M. B., Bennett, R. M., Bombardier, C., Goldenberg, D. L., Tugwell, P., Campbell, S. M., Abeles, M., Clark, P., et al. (1990) · Arthritis & Rheumatism · doi:10.1002/art.1780330203 · Cited by 9,563
Self-citationTsokos, G. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-37754-6.50094-4 · Cited by 3,990
(1992) · PubMed · Cited by 3,804
Millan, M. J. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00009-6 · Cited by 3,035
The prevalence and characteristics of fibromyalgia in the general population
Wolfe, F., Ross, K., Anderson, J., Russell, I. J., & Hebert, L. E. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780380104 · Cited by 2,425
Psychological and neural mechanisms of the affective dimension of pain
Price, D. D. (2000) · Science · doi:10.1126/science.288.5472.1769 · Cited by 2,092
The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders
Heim, C., Ehlert, U., & Hellhammer, D. H. (2000) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(99)00035-9 · Cited by 1,688
Diatchenko, L., Slade, G. D., Nackley, A. G., Bhalang, K., Sigurdsson, A., Belfer, I., Goldman, D., Xu, K., Shabalina, S. A., Shagin, D., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi013 · Cited by 1,280
Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia
Gracely, R. H., Petzke, F., Wolf, J. M., & Clauw, D. J. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10225 · Cited by 1,263
Kaplan and Sadock's Comprehensive Text Book of Psychiatry
Saldanha, D. (2005) · Medical Journal Armed Forces India · doi:10.1016/s0377-1237(05)80189-3 · Cited by 1,164
Research works printed but not linked: 5
- Yunus, 2000, Central sensitivity syndromes: a unified concept for fibromyalgia and other similar maladies, J Indian Rheumatism Assoc, 8, 27
- Vecchiet, 1994, Comparative sensory evaluation of parietal tissue in painful and non-painful areas in fibromyalgia and myofascial pain syndrome, vol. 2, 177
- Banic, 2004, Evidence for spinal cord hypersensitivity in chronic pain after whiplash injury, Pain, 107, 7, 10.1016/j.pain.2003.05.001 · DOI
- Arnold, 2003, Genetic linkage of fibromyalgia to the serotonin receptor 2A on chromosome 13 and the HLA region of chromosome 6, Arthritis Rheum, 48, S228
- Sorensen, 1997, Fibromyalgia—are there different mechanisms in the processing of pain?, J Rheumatol, 24, 1615
Cited by
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Pharmacological interventions for somatoform disorders in adults
Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,369
What we know about primary dysmenorrhea today: a critical review.
Iacovides, S., Avidon, I., & Baker, F. (2015) · Human Reproduction Update · doi:10.1093/humupd/dmv039 · Cited by 973
The Development and Psychometric Validation of the Central Sensitization Inventory
Mayer, T. G., Neblett, R., Cohen, H. M., Howard, K. J., Choi, Y. H., Williams, M. J., Perez, Y., & Gatchel, R. J. (2011) · Pain Practice · doi:10.1111/j.1533-2500.2011.00493.x · Cited by 1,017
Pain and emotion: a biopsychosocial review of recent research
Lumley, M. A., Cohen, J. L., Borszcz, G. S., Cano, A., Radcliffe, A. M., Porter, L. S., Schubiner, H., & Keefe, F. J. (2011) · Journal of Clinical Psychology · doi:10.1002/jclp.20816 · Cited by 836
Neblett, R., Cohen, H., Choi, Y., Hartzell, M. M., Williams, M., Mayer, T. G., & Gatchel, R. J. (2013) · The Journal of Pain · doi:10.1016/j.jpain.2012.11.012 · Cited by 757
Metadata
- Authors
- Yunus, M. B.
- Affiliations
- Peoria campus of the University of Illinois System (US)
- Corresponding author
- Yunus, Muhammad B.
- Venue
- Seminars in Arthritis and Rheumatism
- Publisher
- Elsevier BV
- Published
- 2007-06
- Volume
- 36
- Issue
- 6
- Pages
- 339-356
- ISSN
- 0049-0172 (ISSN-L)
- OpenAlex
- W1967034335
- Cited by
- 780
- References
- 244
- Citations by year
- 2026: 32 · 2025: 30 · 2024: 43 · 2023: 36 · 2022: 38 · 2021: 55 · 2020: 44 · 2019: 35 · 2018: 56 · 2017: 41 · 2016: 42 · 2015: 58 · 2014: 46 · 2013: 51 · 2012: 38
- FWCI
- 4.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Arthritis and Rheumatism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- fibromyalgia, central sensitivity syndromes, central sensitization, irritable bowel syndrome, headache, chronic fatigue syndrome, biopsychosocial model, neuroendocrine dysfunction, psychosocial factors
- MeSH terms
- Fibromyalgia, Humans, Fatigue Syndrome, Chronic, Headache Disorders, Irritable Bowel Syndrome
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