The c-Myc target gene network
Dang, Chi V., O’Donnell, Kathryn A., Zeller, Karen I., Nguyen, Tam, Osthus, Rebecca C., Li, Feng·2006·Seminars in Cancer Biology
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- Polyamine synthesis as a target of MYC oncogenesAndré S. Bachmann, Dirk Geerts · 2018 · Journal of Biological Chemistry
- Cdc45 Is a Critical Effector of Myc-Dependent DNA Replication StressSeetha V. Srinivasan, David Dominguez-Sola, Lily C. Wang, Olivier Hyrien, Jean Gautier · 2013 · Cell Reports
- Sfp1 Interaction with TORC1 and Mrs6 Reveals Feedback Regulation on TOR SignalingHarri Lempiäinen, Aino Uotila, Jörg Urban, Ilse Dohnal, Gustav Ammerer, Robbie Loewith, David Shore · 2009 · Molecular Cell
- The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA BindingVictoria H. Cowling, Michael D. Cole · 2007 · Molecular and Cellular Biology
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- Blocking Myc to Treat Cancer: Reflecting on Two Decades of OmomycDaniel Massó-Vallés, Laura Soucek · 2020 · Cells
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- HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-MycYinghui Li, Zhen Wang, Hui Shi, Hang Li, Leilei Li, Runping Fang, Xiaoli Cai, Bowen Liu, Xiaodong Zhang, Lihong Ye · 2016 · Cancer Research
- MYCN-regulated microRNAs repress estrogen receptor-α ( ESR1 ) expression and neuronal differentiation in human neuroblastomaJakob Lovén, Nikolay Zinin, Therese Wahlström, Inga Müller, Petter Brodin, Erik Fredlund, Ulf Ribacke, Andor Pivarcsi, Sven Påhlman, Marie Arsenian‐Henriksson · 2010 · Proceedings of the National Academy of Sciences
- Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancerHongyu Liu, Chuanbing Zang, Anna Emde, Maricarmen D. Planas-Silva, Marleen Rosche, Andrea Kühnl, Carsten‐Oliver Schulz, Elena Elstner, Kurt Possinger, Jan Eucker · 2008 · European Journal of Pharmacology
- N-Myc Regulates a Widespread Euchromatic Program in the Human Genome Partially Independent of Its Role as a Classical Transcription FactorRebecca F. Cotterman, Victor X. Jin, Sheryl R. Krig, Jessica M. Lemen, Alice Wey, Peggy Farnham, Paul S. Knoepfler · 2008 · Cancer Research
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- The Interplay Between MYC and HIF in the Warburg EffectChi Van Dang · 2008 · Ernst Schering Research Foundation workshop/Ernst Schering Foundation Symposium proceedings
- MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial CellsTsuyoshi Iwata, Denise Schultz, Jessica L Hicks, Gretchen K. Hubbard, Laura N. Mutton, Tamara Levin Lotan, Carlise R. Bethel, Matthew T. Lotz, Srinivasan Yegnasubramanian, William G. Nelson et al. · 2010 · PLoS ONE
- MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cellsSai-Wen Tang, Wen-Hsin Chang, Yih-Ching Su, Yu‐Chi Chen, Yen-Han Lai, Pei-Tzu Wu, Chyong‐Ing Hsu, Wei‐Chou Lin, Ming‐Kuen Lai, Jung‐Yaw Lin · 2008 · Cancer Letters
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- The Kaposi's Sarcoma-Associated Herpesvirus LANA Protein Stabilizes and Activates c-MycJianyong Liu, Heather J. Martin, Gangling Liao, S. Diane Hayward · 2007 · Journal of Virology
- Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc LevelsSimone Buraschi, Nutan Pal, Nadia Tyler-Rubinstein, Rick T. Owens, Thomas Neill, Renato V. Iozzo · 2010 · Journal of Biological Chemistry
- Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomasIwona Włodarska, Daan Dierickx, Vera Vanhentenrijk, Katrien Van Roosbroeck, H Pospíšilová, Francesca Minnei, Gregor E. G. Verhoef, José Thomas, Peter Vandenberghe, Chris De Wolf‐Peeters · 2008 · Blood
- Mitochondrial Structure, Function and Dynamics Are Temporally Controlled by c-MycJ. Anthony Graves, Yudong Wang, Sunder Sims‐Lucas, Edward Cherok, Kristi D. Rothermund, Maria F. Branca, Jennifer D. Elster, Donna Beer–Stolz, Bennett Van Houten, Jerry E. Vockley et al. · 2012 · PLoS ONE
- LncRNA‐MIF, a c‐Myc‐activated long non‐coding RNA, suppresses glycolysis by promoting Fbxw7‐mediated c‐Myc degradationPengfei Zhang, Limian Cao, Pingsheng Fan, Yide Mei, Mian Wu · 2016 · EMBO Reports
- Myc and its interactors take shapeWilliam B. Tu, Sara Helander, Robert Pilstål, K. Ashley Hickman, Corey Lourenco, Igor Jurišica, Brian Raught, Björn Wallner, Maria Sunnerhagen, Linda Z. Penn · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
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- Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC ExpressionKenneth M. Felsenstein, Lindsey B. Saunders, John K. Simmons, Elena C. Leon, David R. Calabrese, Shuling Zhang, Aleksandra M. Michalowski, Peter C. Gareiss, Beverly A. Mock, John S. Schneekloth · 2015 · ACS Chemical Biology
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- Drugging the undruggable: Transcription therapy for cancerChunhong Yan, Paul J. Higgins · 2012 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- BCYRN1, a c-MYC-activated long non-coding RNA, regulates cell metastasis of non-small-cell lung cancerTao Hu, Yu-Run Lu · 2015 · Cancer Cell International
- Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish developmentXiefan Fang, Cammi Thornton, Brian E. Scheffler, Kristine L. Willett · 2013 · Environmental Toxicology and Pharmacology
- Tristetraprolin Impairs Myc-Induced Lymphoma and Abolishes the Malignant StateRobert J. Rounbehler, Mohammad Fallahi, Chunying Yang, Meredith A. Steeves, Weimin Li, Joanne R. Doherty, Franz X. Schaub, Sandhya Sanduja, Dan A. Dixon, Perry J. Blackshear et al. · 2012 · Cell
- Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 bindingCecilia Andrésen, Sara Helander, Alexander S. Lemak, Christophe Farès, Veronika Csizmók, Jonas Carlsson, Linda Z. Penn, Julie Deborah Forman-Kay, C.H. Arrowsmith, Patrik Lundström et al. · 2012 · Nucleic Acids Research
- TOR signaling in invertebratesAlexandre Soulard, Adiel Cohen, Michael N. Hall · 2009 · Current Opinion in Cell Biology
- Targeted Nanoparticles Deliver siRNA to MelanomaYunching Chen, Surendar Reddy Bathula, Qi Yang, Leaf Huang · 2010 · Journal of Investigative Dermatology
- Split-luciferase complementary assay: applications, recent developments, and future perspectivesTaha Azad, Amin Tashakor, Saman Hosseinkhani · 2014 · Analytical and Bioanalytical Chemistry
- c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesisYuchen Feng, Xiaoying Liu, Teng Liu, Qiang Ji, Yongyan Wu, Jinming Li, Wei Gao, Yuan Yuan Zhang, Ting La, Hessam Tabatabaee et al. · 2020 · Nature Communications
- New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor CellsEva Gottfried, Sven Arke Lang, Kathrin Renner, Anja‐Katrin Bosserhoff, Wolfram Gronwald, Michael Rehli, Sabine Einhell, Isabel Gedig, Katrin Singer, Anton Seilbeck et al. · 2013 · PLoS ONE
- Review of Chromium (VI) Apoptosis, Cell-Cycle-Arrest, and CarcinogenesisArthur O.S. Chiu, Xianglin Shi, W. K. P. LEE, Richard Hill, Timothy P. Wakeman, Alan J. Katz, Bo Xu, Naresh S. Dalal, John D. Robertson, Chao Chen et al. · 2010 · Journal of Environmental Science and Health Part C
- Inhibition of transcription factors with small organic moleculesThorsten Berg · 2008 · Current Opinion in Chemical Biology
- Akt and c-Myc Differentially Activate Cellular Metabolic Programs and Prime Cells to Bioenergetic InhibitionYongjun Fan, Kathleen G. Dickman, Wei‐Xing Zong · 2009 · Journal of Biological Chemistry
- Small Molecule Inhibitors of Wnt/β-Catenin/Lef-1 Signaling Induces Apoptosis in Chronic Lymphocytic Leukemia Cells In Vitro and In VivoRajesh Kumar Gandhirajan, Peter Staib, Katharina Minke, Iris Gehrke, Günther Plickert, Axel Schlösser, Esther Katharina Schmitt, Michael J. Hallek, Karl‐Anton Kreuzer · 2010 · Neoplasia
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- A Genome-Wide Screen for β-Catenin Binding Sites Identifies a Downstream Enhancer Element That Controls c -Myc Gene ExpressionGregory S. Yochum, Ryan Cleland, Richard H. Goodman · 2008 · Molecular and Cellular Biology
- MicroRNAs as regulators and mediators of c-MYC functionRené Jackstadt, Heiko Hermeking · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
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- MYU, a Target lncRNA for Wnt/c-Myc Signaling, Mediates Induction of CDK6 to Promote Cell Cycle ProgressionYoshihiro Kawasaki, Mimon Komiya, Kosuke Matsumura, Lumi Negishi, Sakiko Suda, Masumi Okuno, Naoko Yokota, Tomoya Osada, Takeshi Nagashima, Masaya Hiyoshi et al. · 2016 · Cell Reports
- Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotectionNarsa M. Reddy, Steven R. Kleeberger, Masayuki P. Yamamoto, Thomas W. Kensler, Catherine Scollick, Shyam S. Biswal, Sekhar P. Reddy · 2007 · Physiological Genomics
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- c-Myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1Victoria H. Cowling, Celina M. D’Cruz, Lewis A. Chodosh, Michael D. Cole · 2007 · Molecular and Cellular Biology
- Expression Profiles of MYC Protein and MYC Gene Rearrangement in LymphomasKaren M. Chisholm, Charles D. Bangs, Carlos E. Bacchi, Hernan F. Molina-Kirsch, Athena M. Cherry, Yasodha Natkunam · 2015 · The American Journal of Surgical Pathology
- MYC and Transcription ElongationPeter B. Rahl, R A Young · 2014 · Cold Spring Harbor Perspectives in Medicine
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- How does Epstein–Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?Martin J. Allday · 2009 · Seminars in Cancer Biology
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- Deep Sequencing of MYC DNA-Binding Sites in Burkitt LymphomaVolkhard Seitz, Peter Butzhammer, Burkhard Hirsch, Jochen Hecht, Ines Gütgemann, Anke Ehlers, Dido Lenze, Elisabeth Oker, Anke Sommerfeld, Edda von der Wall et al. · 2011 · PLoS ONE
- Strategically targeting MYC in cancerValeriya Posternak, Michael D. Cole · 2016 · F1000Research
- Therapeutic Approaches Targeting MYC-Driven Prostate CancerRichard J. Rebello, Richard B. Pearson, Ross D. Hannan, Luc Furic · 2017 · Genes
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- The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor developmentQiang Zhang, Li Xu, Kasa Cui, Cheng Liu, Mingzhi Wu, Edward V. Prochownik, Youjun Li · 2019 · Cell Death and Differentiation
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- Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation.M. Wall, G. Poortinga, K. Hannan, R. Pearson, R. Hannan, G. McArthur · 2008 · Blood
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- Myc's other life: stem cells and beyondElisa Laurenti, Anne Wilson, Andreas Trumpp · 2009 · Current Opinion in Cell Biology
- Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced DifferentiationMichaela Frye, Amanda G. Fisher, Fiona M. Watt · 2007 · PLoS ONE
- β-Catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastma cellsXiangrong Liu, Lei Wang, Shangfeng Zhao, Xunming Ji, Yumin Luo, Feng Ling · 2010 · Medical Oncology
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- Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizerDaniel Shiu‐Hin Chan, Hui Yang, Maria Hiu‐Tung Kwan, Zhen Cheng, Paul Lee, Li‐Ping Bai, Zhi‐Hong Jiang, Chun‐Yuen Wong, Wang Fun Fong, Chung‐Hang Leung et al. · 2011 · Biochimie
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- Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial BiogenesisPeiwei Huangyang, Fuming Li, Pearl Lee, Itzhak Nissim, Aalim M. Weljie, Anthony Mancuso, Bo Li, Brian Keith, Sam S. Yoon, Marie Celeste Simon · 2019 · Cell Metabolism
- Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain TumorigenesisChi-hwa Wu, Debashis Sahoo, Constadina Arvanitis, Nicole Bradon, David L. Dill, Dean W. Felsher · 2008 · PLoS Genetics
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- Genomic and Proteomic Analysis Reveals a Threshold Level of MYC Required for Tumor MaintenanceCatherine M. Shachaf, Andrew J. Gentles, Sailaja V Elchuri, Debashis Sahoo, Yoav Soen, Orr Sharpe, Omar D. Perez, Maria Chang, Dennis Mitchel, William H. Robinson et al. · 2008 · Cancer Research
- Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung AdenocarcinomasAudrey Bouillez, Hasan N. Rajabi, Sean P. Pitroda, Caining Jin, Maroof Alam, Akriti Kharbanda, Ashujit Tagde, Kwok‐Kin Wong, Donald W. Kufe · 2016 · Cancer Research
- Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1)Markus Hartl, Andrea Nist, M. Imran Khan, Taras Valovka, Klaus Bister · 2009 · Proceedings of the National Academy of Sciences
- P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression in diffuse large B-cell lymphomaXuan J. Wang, Leonard Jeffrey Medeiros, Carlos Bueso-Ramos, Guilin Tang, Sa Wang, Yasuhiro Oki, Parth Anil Desai, Joseph David Khoury, Roberto N. Miranda, Zhenya Tang et al. · 2016 · Modern Pathology
- Curcumin Inhibits Gastric Carcinoma Cell Growth and Induces Apoptosis by Suppressing the Wnt/β-Catenin Signaling PathwayRuzhen Zheng, Qinghua Deng, Yuehua Liu, Pengjun Zhao · 2017 · Medical Science Monitor
- Altering chemosensitivity by modulating translation elongationRobert, Francis, Carrier, Marilyn, Rawe, Svea, Chen, Samuel, Lowe, Scott, Pelletier, Jerry · 2009 · PLoS ONE
- The human papillomavirus E7 oncoprotein as a regulator of transcriptionWilliam K. Songock, Seong‐Man Kim, Jason M. Bodily · 2016 · Virus Research
- Max-independent functions of Myc in Drosophila melanogasterDominik Steiger, Michael Furrer, Daniela Schwinkendorf, Peter Gallant · 2008 · Nature Genetics