mTOR: Role in cancer, metastasis and drug resistance

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Items 101–200 of 485

1. Downregulation of NEDD4L by EGFR signaling promotes the development of lung adenocarcinoma
   Guoyin Li, Zewen Song, Changjing Wu, Xiaoyan Li, Liping Zhao, Binghua Tong, Zhenni Guo, Meiqing Sun, Jin Zhao, Huina Zhang et al. · 2022 · Journal of Translational Medicine
2. Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality
   Pu Li, Tingting Chen, Peng Kuang, Fujun Liu, Zhongmin Li, Fangfang Liu, Yu Wang, Wenfeng Zhang, Xiuyu Cai · 2022 · Cell Death and Disease
3. The allosteric mechanism of mTOR activation can inform bitopic inhibitor optimization
   Yonglan Liu, Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov · 2023 · Chemical Science
4. TIPRL, a Novel Tumor Suppressor, Suppresses Cell Migration, and Invasion Through Regulating AMPK/mTOR Signaling Pathway in Gastric Cancer
   Meng Luan, Shanshan Shi, Duan‐Bo Shi, Haiting Liu, Ran‐Ran Ma, Xiao-Qun Xu, Yujing Sun, Peng Gao · 2020 · Frontiers in Oncology
5. Interplay Between m6A RNA Methylation and Regulation of Metabolism in Cancer
   Youchaou Mobet, Xiaoyi Liu, Tao Liu, Jianhua Yu, Ping Yi · 2022 · Frontiers in Cell and Developmental Biology
6. CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma
   Tong Cao, Yue Cui, Yingying Wang, Linhui Wu, Ke Yu, Kai Chen, Jun Xia, Yuyun Li, Zhiwei Peter Wang, Jia Ma · 2022 · APOPTOSIS
7. Mechanism and application of ferroptosis in colorectal cancer
   Yang Liu, Yewei Zhang, Yingyi Zhang, Zhe Fan · 2022 · Biomedicine & Pharmacotherapy
8. A Narrative Review of Current Knowledge on Cutaneous Melanoma
   Bogdan Marian Caraban, Mariana Aşchie, Mariana Deacu, Georgeta Camelia Cozaru, Mihaela Butcaru Pundiche, Cristian Ionuţ Orǎșanu, Raluca Ioana Vodă · 2024 · Clinics and Practice
9. Interplay between the RNA binding‐protein Musashi and developmental signaling pathways
   Pablo Shimaoka Chagas, Mirella Baroni, María Sol Brassesco, Luíz Gonzaga Tone · 2019 · The Journal of Gene Medicine
10. MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR
    Xiaowei Chang, Chang Tian, Yuanyuan Jia, Yu Cai, Pu Yan · 2023 · BMC Cancer
11. Signaling Pathways Involved in Acute Pancreatitis
    Mengchen Luo, Ting Jin, Yi Ming Fang, Feng Chen, Lujian Zhu, Jin Bai, Jin Wen Ding · 2025 · Journal of Inflammation Research
12. CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling
    Shijun Yu, Qingqing Hu, Kailing Fan, Chen Yang, Yong Gao · 2021 · Journal of Cell Communication and Signaling
13. Methionine and leucine induce ARID1A degradation to promote mTOR expression and milk synthesis in mammary epithelial cells
    Hao Qi, Lulu Wang, Minghui Zhang, Zhe Wang, Xuejun Gao, Meng Li · 2021 · The Journal of Nutritional Biochemistry
14. Modulation of Sirt1-mTORC1 Pathway in Microglia Attenuates Retinal Ganglion Cell Loss After Optic Nerve Injury
    Qianxue Mou, Ke Yao, Meng Ye, Bowen Zhao, Yuanyuan Hu, Xiaotong Lou, Huixia Li, Hong Zhang, Yin Zhao · 2021 · Journal of Inflammation Research
15. Inhibition of Non-Small Cell Lung Cancer Proliferation and Survival by Rosemary Extract Is Associated with Activation of ERK and AMPK
    Eric J. O’Neill, Jessy Moore, Joon Seon Song, Evangelia Tsiani · 2021 · Life
16. RETRACTED: P311 Facilitates the Angiogenesis and Wound Healing Function of MSCs by Increasing VEGF Production
    Zhihui Liu, Jiacai Yang, Yunxia Chen, Cheng Chen, Jue Wang, Yew Mun Lee, Wenxia Zheng, Ruoyu Shang, Yuanyang Tang, Xiaorong Zhang et al. · 2022 · Frontiers in Immunology · Retracted
17. Signals transduced by Eph receptors and ephrin ligands converge on MAP kinase and AKT pathways in human cancers
    Andreas Lau, Nghia Le, Claudia Nguyen, Raj P. Kandpal · 2022 · Cellular Signalling
18. Vitamin K: New insights related to senescence and cancer metastasis
    Anqi Chen, Jialu Li, Nianxuan Shen, Haifeng Huang, Qinglei Hang · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
19. TIPE1‐mediated autophagy suppression promotes nasopharyngeal carcinoma cell proliferation via the AMPK/mTOR signalling pathway
    Yongliang Liu, Xiangqin Qi, Zhenan Zhao, Daoliang Song, Lianqing Wang, Qiaoli Zhai, Xiaoning Zhang, Peiqing Zhao, Xinxin Xiang · 2020 · Journal of Cellular and Molecular Medicine
20. Nanostructured lipid carrier co-delivering paclitaxel and doxorubicin restrains the proliferation and promotes apoptosis of glioma stem cells via regulating PI3K/Akt/mTOR signaling
    Lisha Chang, Yunhe Zhang, Min Li, Xiaojing Zhao, Dali Wang, Jian Liu, Fuling Zhou, Jiang Zhang · 2021 · Nanotechnology
21. mTORopathies in Epilepsy and Neurodevelopmental Disorders: The Future of Therapeutics and the Role of Gene Editing
    Marina Ottmann Boff, Fernando Antônio Costa Xavier, Fernando Mendonça Diz, Júlia Budelon Gonçalves, Luan Oliveira Ferreira, Jean Zambeli, Douglas Bottega Pazzin, Thales Thor Ramos Previato, Helena Scartassini Erwig, João Ismael Budelon Gonçalves et al. · 2025 · Cells
22. Synergistic targeting strategies for prostate cancer
    Xuanji Li, Zeyu Han, Jianzhong Ai · 2025 · Nature Reviews Urology
23. Signaling alterations caused by drugs and autophagy
    Paul Dent, Laurence A. Booth, Andrew Stewart Poklepovic, John F. Hancock · 2019 · Cellular Signalling
24. mTOR/NF-κB signaling pathway protects hippocampal neurons from injury induced by intermittent hypoxia in rats
    Chuqin Zhang, Song Yi, Bobei Chen, Panpan Cui, Yan Wang, Yanzhong Li · 2020 · International Journal of Neuroscience
25. Mechanism and Role of Endoplasmic Reticulum Stress in Osteosarcoma
    Peijun Zhu, Ting Li, Qingqing Li, Yawen Gu, Yuan Shu, Kaibo Hu, Leifeng Chen, Xiaogang Peng, Jie Peng, Liang Hao · 2022 · Biomolecules
26. Tuberous Sclerosis, Type II Diabetes Mellitus and the PI3K/AKT/mTOR Signaling Pathways—Case Report and Literature Review
    Claudia Maria Jurca, Kinga Kozma, Codruța Diana Petcheși, Dana Carmen Zaha, Ioan Magyar, Mihai Alexandru Munteanu, Lucian Faur, Aurora Alexandra Jurca, Dan Bembea, Emilia Maria Severin et al. · 2023 · Genes
27. Review the progression of ovarian clear cell carcinoma from the perspective of genomics and epigenomics
    Tong An, Xiangjie Di, Xia Zhao, Xiao Liang · 2023 · Frontiers in Genetics
28. Research progress on traditional Chinese medicine-induced apoptosis signaling pathways in ovarian cancer cells
    Yu Wang, Liangzhen Xie, Fang-Yuan Liu, Dan‐Ni Ding, Wei Wei, Feng‐Juan Han · 2023 · Journal of Ethnopharmacology
29. Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy
    Aleksandra Stanojević, Martina K. Samiotaki, Vasiliki Lygirou, Mladen Marinković, Vladimir Nikolić, Suzana Stojanović-Rundić, Radmila N. Jankovic, Antonia Vlahou, George Panayotou, Remond J.A. Fijneman et al. · 2023 · International Journal of Molecular Sciences
30. A paradoxical role for sestrin 2 protein in tumor suppression and tumorigenesis
    Junsheng Qu, Moyi Luo, Jingwen Zhang, Fang Han, Ningning Hou, Ruiyan Pan, Xiaodong Sun · 2021 · Cancer Cell International
31. mTORC2 regulates ribonucleotide reductase to promote DNA replication and gemcitabine resistance in non-small cell lung cancer
    Tian, Ling, Chen, Congcong, Guo, Yanguan, Zhang, Fan, Mi, Jinye, Feng, Qi, Lin, Shengbin, Xi, Naite, Tian, Jiaxin, Yu, Li et al. · 2021 · Neoplasia
32. Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System
    Jean-Paul Bryant, Adam Shapira Levy, John D. Heiss, Yeshavanth Banasavadi‐Siddegowda · 2021 · Cancers
33. Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth
    Ksenija Korać, Devaraja Rajasekaran, Tyler Sniegowski, Bradley K. Schniers, Andrew Ibrahim, Yangzom Doma Bhutia · 2022 · Biochemical Journal
34. mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation
    Shuo Wan, Yadong Sun, Jiamin Fu, Hongrui Song, Zhi‐Qiang Xiao, Quanli Yang, Sanfeng Wang, Gongwang Yu, Peiran Feng, Wenkai Lv et al. · 2022 · Cell Death and Disease
35. The multifaced role and therapeutic regulation of autophagy in ovarian cancer
    Fahimeh Nokhostin, Mahboobeh Azadehrah, Malihe Azadehrah · 2022 · Clinical & Translational Oncology
36. Cardiomyopathies and a brief insight into DOX-induced cardiomyopathy
    Sampat Singh Tanwar, Sumeet Dwivedi, Sheema Khan, Seema Sharma · 2025 · The Egyptian Heart Journal
37. Engineered nanomedicines for tumor vasculature blockade therapy
    Duoyi Zhao, Xu Huang, Zhiyu Zhang, Jianxun Ding, Yan Cui, Xuesi Chen · 2021 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
38. Autophagic degradation of SQSTM1 enables fibroblast activation to accelerate wound healing
    Yujiao Xu, Xin Gu, Wenshu Li, Boyang Lin, Yiting Xu, Qingcheng Wei, Qingyuan Liu, Yamin Zhao, Rongzhuo Long, Hu‐Lin Jiang et al. · 2025 · Autophagy
39. miR-328-3p promotes migration and invasion by targeting H2AFX in head and neck squamous cell carcinoma
    Huiling Ma, Chao Liu, Shuiting Zhang, Wenhui Yuan, Junli Hu, Donghai Huang, Xin Zhang, Yong Liu, Yuanzheng Qiu · 2021 · Journal of Cancer
40. A mixed blessing for liver transplantation patients — Rapamycin
    Guang-Han Fan, Chen-Zhi Zhang, Fengqiang Gao, Xuyong Wei, Sunbin Ling, Kai Wang, Jianguo Wang, Shusen Zheng, Mehrdad Nikfarjam, Xiao Xu · 2022 · Hepatobiliary & pancreatic diseases international
41. Anti-tumor effect of AZD8055 against bladder cancer and bladder cancer-associated macrophages
    Weimin Hu, Yunlong Zhang, Jinzhuo Ning, Ming Li, Yuqi Tang, Linzhi Li, Cheng Fan, Weimin Yu · 2023 · Heliyon
42. Application of nanotechnology in reversing therapeutic resistance and controlling metastasis of colorectal cancer
    Sheng-Nan Ren, Zhan-Yi Zhang, Rui-Jie Guo, Daren Wang, Fangfang Chen, Xuebo Chen, Xuedong Fang · 2023 · World Journal of Gastroenterology
43. Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia–Reperfusion With Increased Blood–Brain Barrier Disruption
    OAK ZA CHI, Xia Liu, Sean Cofano, Nikhil Patel, Estela Jacinto, Harvey R. Weiss · 2021 · Frontiers in Physiology
44. IGF2 loss of imprinting enhances colorectal cancer stem cells pluripotency by promoting tumor autophagy
    Tianyi Gao, Xiangxiang Liu, Bangshun He, Yuqin Pan, Shukui Wang · 2020 · Aging
45. SREBP2 inhibitor betulin sensitizes hepatocellular carcinoma to lenvatinib by inhibiting the mTOR/IL-1β pathway
    Ming-Hao Fan, Zhenmei Chen, Weiqing Shao, Yiran Chen, Zhifei Lin, Chenhe Yi, Yitong Li, Lu Lu, Yu Zhou, Jing Lin · 2023 · Acta Biochimica et Biophysica Sinica
46. Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer
    Chunming Li, Xinna Du, Hu Zhang, Shuang Liu · 2024 · CytoJournal
47. Harmaline isolated from Peganum harmala suppresses growth of esophageal squamous cell carcinoma through targeting mTOR
    Yuanyuan Zhang, Xiaodan Shi, Xiaomeng Xie, Kyle Vaughn Laster, Mengjun Pang, Kangdong Liu, Joonsung Hwang, Dong Joon Kim · 2021 · Phytotherapy Research
48. The inhibitory effect of LINC00261 upregulation on the pancreatic cancer EMT process is mediated by KLF13 via the mTOR signaling pathway
    B. Li, S. Pang, J. Dou, Changlin Zhou, Baiyong Shen, Yu Zhou · 2022 · Clinical & Translational Oncology
49. ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to FGFR1 inhibitors through amino acid metabolic reprogramming
    Zijian Zhang, Qifang Wu, Anqi Ren, Qian Chen, Jiangzhou Shi, Jia-peng Li, Xiyu Liu, Zhijie Zhang, Yu-zhe Tang, Yuan Zhao et al. · 2023 · Acta Pharmacologica Sinica
50. Anti-Tumor Effect and Mechanism Study of Caloric Restriction, Achieved by Time-Restricted Feeding, in Mice
    Weisheng Lu, Jue Wang, Chengji Wang, Haijie Wang, Wenhao Gao, Shouchong Ye, Ruling Shen · 2024 · Cancer Control
51. The Association of Aberrant Expression of FGF1 and mTOR-S6K1 in Colorectal Cancer
    Tinghui Duan, Diyuan Zhou, Yizhou Yao, Xinyu Shao · 2021 · Frontiers in Oncology
52. Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs
    Linyan Wan, Yanan Wang, Jie Li, Yani Wang, Hong Zhang · 2022 · Acta Biochimica et Biophysica Sinica
53. Pin1 inhibitor API-1 sensitizes BRAF-mutant thyroid cancers to BRAF inhibitors by attenuating HER3-mediated feedback activation of MAPK/ERK and PI3K/AKT pathways
    Hui Dang, Mengjun Sui, Qingyuan He, Jingyi Xie, Yan Liu, Peng Hou, Meiju Ji · 2023 · International Journal of Biological Macromolecules
54. RUNX1 promotes proliferation and migration in non‐small cell lung cancer cell lines via the mTOR pathway
    Huan Ma, Siyu Jiang, Yinan Yuan, Ji Li, Yizhuo Li, Yanping Lv, Tengjiao Du, Jingqian Guan, Xizi Jiang, Lei Tian et al. · 2023 · The FASEB Journal
55. FBXW7 and human tumors: mechanisms of drug resistance and potential therapeutic strategies
    Wanqing Wang, Kaipeng Jiang, Xue Liu, Ju Li, Wenshuo Zhou, Chang Wang, Jiuwei Cui, Tingting Liang · 2023 · Frontiers in Pharmacology
56. mTOR aggravated CD4+ T cell pyroptosis by regulating the PPARγ–Nrf2 pathway in sepsis
    Guoyu Zhao, Yawen Xie, Xianli Lei, Ran Guo, Na Cui · 2024 · International Immunopharmacology
57. The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway
    Hajer Tlili, Anca Macovei, Daniela Buonocore, Manuela Lanzafame, Hanen Najjaa, Anita Lombardi, Andrea Pagano, Maurizia Dossena, Manuela Verri, Abdelkarim Ben Arfa et al. · 2021 · BMC Complementary Medicine and Therapies
58. A Novel Immune‐Related Gene Signature Predicts Prognosis of Lung Adenocarcinoma
    Chao Ma, Feng Li, Ziming Wang, Huan Luo · 2022 · BioMed Research International
59. The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR‐99a/mTOR‐Mediated Autophagy and Apoptosis
    Huifang Hu, Jia‐Ying Fu, Lei Han, Gui‐Bin Gao, Wei‐Xia Zhang, Si‐Ming Yu, Nan Li, Yang‐Jia Li, Yi‐Fan Lu, Xiao‐Feng Ding et al. · 2024 · Advanced Science
60. Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells
    Johany Peñailillo, Miriam Palacios, Constanza Mounieres, Rosana Muñoz, Paula G. Slater, Elena De Domenico, Ilya Patrushev, Mike J. Gilchrist, Juan Larraı́n · 2021 · npj Regenerative Medicine
61. Implication of mTOR Signaling in NSCLC: Mechanisms and Therapeutic Perspectives
    Antonios N. Gargalionis, Kostas A. Papavassiliou, Athanasios G. Papavassiliou · 2023 · Cells
62. Ferroptosis: insight into the treatment of hepatocellular carcinoma
    Chuanjie Liao, You-Wu He, Xin-Ning Luo, Gan-Lu Deng · 2024 · Cancer Cell International
63. Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine‑resistant myeloid leukemia cells
    Yu‐Hsin Tseng, Rei‐Cheng Yang, Shyh‐Shin Chiou, Tzong‐Ming Shieh, Yin-Hwa Shih, Pei‐Chin Lin · 2021 · Molecular Medicine Reports
64. Characterization of Gut Microbiota and Exploration of Potential Predictive Model for Hepatocellular Carcinoma Microvascular Invasion
    Ningning Zhang, Zeyu Wang, Jiayu Lv, Shuwen Zhang, Yang Liu, Tian Liu, Wang Li, Lan Gong, Xiaodong Zhang, Emad M. El-Omar et al. · 2022 · Frontiers in Medicine
65. OSI‐027 inhibits the tumorigenesis of colon cancer through mediation of c‐Myc/FOXO3a/PUMA axis
    Jie Lou, Jian‐Xin Lv, Youping Zhang, Zhan‐Ju Liu · 2022 · Cell Biology International
66. The overview of Mitogen-activated extracellular signal-regulated kinase (MEK)-based dual inhibitor in the treatment of cancers
    Hao Wang, Lingling Chi, Fuqiang Yu, Hongling Dai, Xiaojie Si, Chao Gao, Zhengjie Wang, Limin Liu, Jiaxin Zheng, Yu Ke et al. · 2022 · Bioorganic & Medicinal Chemistry
67. Synthesis, characterization, anticancer efficacy evaluation of ruthenium(II) and iridium(III) polypyridyl complexes toward A549 cells
    Lijuan Liang, Yan Yang, Haimei Liu, Fang Yuan, Yuhan Yuan, Wenlong Li, Chunxia Huang, Jing Chen, Yunjun Liu · 2023 · JBIC Journal of Biological Inorganic Chemistry
68. TTI1 promotes non‐small‐cell lung cancer progression by regulating the mTOR signaling pathway
    Ling‐Xian Zhang, Xin Yang, Zhi‐Bo Wu, Zhong‐Min Liao, Ding‐Guo Wang, Shiwei Chen, Feng Lü, Yongbing Wu, Shu‐Qiang Zhu · 2022 · Cancer Science
69. USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway
    Lei Cao, Hongsheng Liu, Cheng Huang, Chao Guo, Luo Sha Zhao, Chao Gao, Yuan Xu, Guige Wang, Naixin Liang, Shanqing Li · 2023 · Biology Direct
70. Leucine Reduced Blood–Brain Barrier Disruption and Infarct Size in Early Cerebral Ischemia-Reperfusion
    OAK ZA CHI, Xia Liu, Jedrick Magsino, Harvey R. Weiss · 2023 · Brain Sciences
71. An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies
    Jing Wang, Yuqi Wen, Yixin Zhang, Zhongming Wang, Yuyang Jiang, Chong Dai, Lianlian Wu, Dongjin Leng, Song He, Xiaochen Bo · 2023 · Journal of Advanced Research
72. Gene Panel of Persister Cells as a Prognostic Indicator for Tumor Repopulation After Radiation
    Yucui Zhao, Yanwei Song, Ruyi Zhao, Minghui Zhao, Qian Huang · 2020 · Frontiers in Oncology
73. Peptide inhibitors: Breaking cancer code
    Fleur Coburn, Yanyamba Nsereko, Amy J. Armstrong, Othman Al Musaimi · 2025 · European Journal of Medicinal Chemistry
74. The neuroinflammatory triumvirate: NF-κB, NLRP3, and mTOR in spinal cord injury
    Ali Darabniya · 2025 · Inflammopharmacology
75. The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway
    Jiayi Huang, Chunshuai Wu, Guanhua Xu, Yue Ming Sun, Chao Gui, Jiawei Fu, Zhiming Cui, Haiming Huang · 2022 · Annals of Translational Medicine
76. Mammalian target of rapamycin; novel insight for management of inflammatory bowel diseases
    Naser‐Aldin Lashgari, Nazanin Momeni Roudsari, Saeideh Momtaz, Amir Hossein Abdolghaffari · 2022 · World Journal of Pharmacology
77. Relationship of mTORC1 and ferroptosis in tumors
    Huilin Liao, Yueqing Wang, Lili Zou, Yanmei Fan, Xinyue Wang, Xiancong Tu, Qiaobai Zhu, Jun Wang, Xiaowen Liu, Chuanjiang Dong · 2024 · Discover Oncology
78. Research advances in natural sesquiterpene lactones: overcoming cancer drug resistance through modulation of key signaling pathways
    Chi Teng, Jiawen Chen, Lisha Shen, Sibao Chen, Guoqing Chen · 2025 · Cancer Drug Resistance
79. UPLC-Q-TOF/MS-Based Metabolomics Approach Reveals Osthole Intervention in Breast Cancer 4T1 Cells
    Xiuyun Li, Chenglun Zhang, Enhui Wu, Liang Han, Xiangliang Deng, Zhongfeng Shi · 2023 · International Journal of Molecular Sciences
80. Self-Assembled Nanodelivery System with Rapamycin and Curcumin for Combined Photo-Chemotherapy of Breast Cancer
    Yanlong Yin, Hong Jiang, Yue Wang, Longyao Zhang, Chunyan Sun, Pan Xie, Kun Zheng, Shaoqing Wang, Qian Yang · 2023 · Pharmaceutics
81. Targeting autophagy drug discovery: Targets, indications and development trends
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82. Crucial Roles of microRNA-Mediated Autophagy in Urologic Malignancies
    Maolei Shen, Xin Li, Biao Qian, Qiang Wang, Shanan Lin, Wenhao Wu, Shuai Zhu, Rui Zhu, Shankun Zhao · 2021 · International Journal of Biological Sciences
83. Role of mTOR through Autophagy in Esophageal Cancer Stemness
    Liang Du, Da Wang, Peter W. Nagle, Andries H. Groen, Hao Zhang, Christina T. Muijs, John Th. M. Plukker, Robert Paul Coppes · 2022 · Cancers
84. Hydrogen Sulfide can Scavenge Free Radicals to Improve Spinal Cord Injury by Inhibiting the p38MAPK/mTOR/NF-κB Signaling Pathway
    Kexin Lin, Yong Zhang, Yanyang Shen, Yiqin Xu, Min Huang, Xuehong Liu · 2024 · NeuroMolecular Medicine
85. Targeting mTOR with curcumin: therapeutic implications for complex diseases
    Danial Khayatan, Seyed Mehrad Razavi, Zahra Najafi Arab, Hadis Nasoori, Abtin Fouladi, Aytak Vahdat Khajeh Pasha, Alexandra E. Butler, Sercan Karav, Saeideh Momtaz, Amir Hossein Abdolghaffari et al. · 2025 · Inflammopharmacology
86. Expression of LAT1 and 4F2hc in Gastroenteropancreatic Neuroendocrine Neoplasms
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87. NRF‑1 directly regulates TFE3 and promotes the proliferation of renal cancer cells
    Wenyuan Zhuang, Xiang Da Dong, Bo Wang, Ning Liu, Hongqian Guo, Chunni Zhang, Weidong Gan · 2021 · Oncology Letters
88. Integrating network pharmacology and experimental models to investigate the mechanisms of dihydroartemisinin in preventing NSCLC progression via mTOR/HIF-1α signaling
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89. Role of autophagy in gastric carcinogenesis
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90. Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin
    Jie Yang, Hasenbilige, Shibo Bao, Shengxiang Luo, Liping Jiang, Qiujuan Li, Ying Kong, Jun Cao · 2023 · Food and Chemical Toxicology
91. Six immune-related promising biomarkers may promote hepatocellular carcinoma prognosis: a bioinformatics analysis and experimental validation
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92. Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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93. TRIM26 inhibits clear cell renal cell carcinoma progression through destabilizing ETK and thus inactivation of AKT/mTOR signaling
    Di Zheng, Jinzhuo Ning, Hao Deng, Yuan Ruan, Cheng Fan · 2024 · Journal of Translational Medicine
94. Fangchinoline Inhibits African Swine Fever Virus Replication by Suppressing the AKT/mTOR/NF-κB Signaling Pathway in Porcine Alveolar Macrophages
    Guanming Su, Xiaoqun Yang, Qisheng Lin, Guoming Su, Jinyi Liu, Li Huang, Weisan Chen, Wen‐Kang Wei, Jianxin Chen · 2024 · International Journal of Molecular Sciences
95. Independent and synergistic effects of extreme heat and NO2 pollution on diabetic nephropathy in a type II diabetes mouse model
    Zipeng Qiao, Xiangling Feng, Wenying Sun, Faming Wang, Chan Lu · 2025 · Environmental Pollution
96. Deficiency in the Treatment Description of mTOR Inhibitor Resistance in Medulloblastoma, a Systematic Review
    Hajar Alammar, Rayan Nassani, Mana M. Alshehri, Alaa A. Aljohani, Bahauddeen M. Alrfaei · 2021 · International Journal of Molecular Sciences
97. Targeting mTOR Signaling by Dietary Polysaccharides in Cancer Prevention: Advances and Challenges
    Mengyuan Li, Zuomin Hu, Tianyi Guo, Tiantian Xie, Yanqin Tang, Xiuxiu Wu, Feijun Luo · 2022 · Journal of Agricultural and Food Chemistry
98. Association of High LAT1 Expression with Poor Prognosis and Recurrence in Colorectal Cancer Patients Treated with Oxaliplatin-Based Adjuvant Chemotherapy
    Yuta Shibasaki, Takehiko Yokobori, Makoto Sohda, Ikuma Shioi, Naoya Ozawa, Chika Komine, Kunihiko Suga, Nobuhiro Nakazawa, Katsuya Osone, Takuya Shiraishi et al. · 2023 · International Journal of Molecular Sciences
99. CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway
    Zhengchen Jiang, Bowen Shi, Yun Zhang, Tianming Yu, Yang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong, Sanyuan Hu, Xiaomin Ma · 2024 · iScience
100. Co-treatment With Everolimus, an mTOR-Specific Antagonist, or Downregulation of ELK1 Enhances the Sensitivity of Pancreatic Cancer Cells to Genistein
     Tianyu Li, Tiantao Kuang, Zhaoshuo Yang, Qiqi Zhang, Wen Zhang, Yue Fan · 2021 · Frontiers in Cell and Developmental Biology