mTOR: Role in cancer, metastasis and drug resistance

Murugan, Avaniyapuram Kannan·2019·Seminars in Cancer Biology
DOI 10.1016/j.semcancer.2019.07.003

Cited by (485)

Items 401–485 of 485

  1. Molecular signaling and its role in drug resistance in hepatocellular carcinomas
    Fayyaz Rasool, Binayak Kumar, Deepu Sharma, Sri Krishna Jayadev Magani · 2022 · Elsevier eBooks
  2. Role of TELO2-interacting protein 1(TTI1) functions as an oncogene by regulating mTOR activity in the progression of non-small cell lung cancer
    Ling-Xian Zhang, Xin Yang, Zhi‐Bo Wu, Zhong‐Min Liao, Ding-Guo Wang, Shiwei Chen, Feng Lu, Yongbing Wu, Shu‐Qiang Zhu · 2022 · Research Square
  3. Pembrolizumab Induced Hypothyroidism: A Case Report
    Sidelya Ecem YİĞİT, İffet Beril GÖKMEN, Yıldız Okuturlar · 2022 · Turkish Journal of Internal Medicine
  4. [The dual mTORC1/2 inhibitor AZD2014 inhibits acute graft rejection in a rat liver transplantation model].
    Hui Liao, Yu Wang, Xiaoyan Xu, C Zhou, J Zhang, K Zhong, Dinghua Yang · 2022 · PubMed Central
  5. ATG5 promotes head and neck squamous cell carcinoma by regulating translation and cell cycle
    Junquan Weng, Huijuan Liu, Hui Zhang, Su Tang, Haidong Fan · 2022 · Research Square
  6. MTOR hypermethylation may associate with the susceptibility and survival of SARS-CoV-2 infections to lung adenocarcinoma patients based on multi-omics data and machine learning
    Yu Peng Guo, Minghao Li, Yang Hu, Tianyi Zang · 2022 · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
  7. Rapamycin Inhibits Human Oral Cancer Cell Growth via the Hsa-miR-199a-3p/mTOR Pathway
    Yujiao Hou, Feifei Lv, Zhai Wenjing, Wei-Na Wang, Yanhao Duan, Shanshan Liu, Yongle Qiu · 2022 · Science of Advanced Materials
  8. Análise do perfil da expressão de canais de zinco no adenocarcinoma renal humano após quimioterapia
    Soraia Barbosa de Oliveira · 2022
  9. Luteolin-Zn Complex Inhibits Invasion and Migration of M2-Like TAMs via the Downregulation of AMPK/mTOR and PI3K/Akt/mTOR Signaling Pathway Under Hypoxia
    Chenyang Mao, Yongling Wang, Zhenhua Xu, Xiaowu Wang, Binbo Fang, Haihua Chen · 2023 · Natural Product Communications
  10. Rapamycin Protects Dopaminergic Neurons by Suppressing Tlr2 Mediated Neuroinflammation and Enhancing Autophagy in Rotenone-Induced Pd Mice
    xifang xie, Songxue Su, Yujiao Huang, Qunli Cui, Weidong Zang · 2023 · Research Square
  11. Voies en aval des récepteurs à activité tyrosine kinase
    Jacques Robert · 2023 · Elsevier eBooks
  12. A scientometric analysis of research trends on targeting mTOR in breast cancer from 2012 to 2022
    Xizhou Zhang, Jinyao Wu, Qiuping Yang, Huiting Tian, Lingzhi Chen, Daitian Zheng, Zeqi Ji, Jiehui Cai, Yexi Chen, Zhiyang Li · 2023 · Frontiers in Oncology
  13. Translational regulation of cell invasion through extracellular matrix—an emerging role for ribosomes
    David R. Sherwood, Isabel W. Kenny-Ganzert, Siddharthan Balachandar Thendral · 2023 · F1000Research
  14. [Rapamycin enhances inhibitory effect of RSL3 on proliferation, invasion and migration of testicular cancer I-10 cells in vitro].
    Bin Li, Yue Wang, F Hou, Jingtong Du, Xiangmin Tong · 2023 · PubMed Central
  15. Genipin as the Active Compound of Gardenia fruits Inhibit Proliferation, Migration and Autophagy of Prostate Cancer through PI3K/AKT Signaling Pathway
    Peiru Dai, Yan Chen, YinYin Wei, Weihua Yin, Chun‐Lin Chen · 2024 · Research Square
  16. Additional file 13 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Xiaomin Li, Wang, Jianjun, Weihao Lin, Qinzi Yuan, Yanxia Lu, Haowei Wang, Yujia Chen, Lixia Chen, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  17. Exploring Gene-Mediated Mechanisms Behind Shared Phenotypes Across Diverse Diseases Using the clGENE Tool
    Zheng Li · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  18. MRPL27 as a new prognostic biomarker involved in immune cell infiltration and hepatocellular carcinoma progression
    Jiaying Yang, Qinghua Lin, Xiayan Liu, Ke Chen, Xinyi Chen, Junyong Han, Zhijun Liao · 2024 · Research Square
  19. Stimulation of inactivated Metschnikowia bicuspidata promotes the growth, and immunity of Eriocheir sinensis larvae
    Tianqi Yu, Weilin Wang, Xiaoxu Zhou, Xingye Lian, Junlei Cheng, Yali Li, Lingling Wang, Linsheng Song · 2024 · Aquaculture
  20. Small-molecule inhibitor of C-terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells
    Céline David, Yadong Sun, Vitalij Woloschin, Melina Vogt, Niklas Dienstbier, David Schlütermann, Lena Berning, Beate Lungerich, Annabelle Friedrich, Seda Akgün et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Mechanism of Monocarboxylate Transporter 1 and Its Methylation in Nasopharyngeal Carcinoma Pathogenesis
    Weihong Tong, Zhengyong Zhu, Ruiyang Zhu, Zihe Wang, Jin Zhu · 2025 · Cancer Biotherapy and Radiopharmaceuticals
  22. Exploring SERTAD4 as a prognostic biomarker and therapeutic target in breast cancer: insights from multidatabase analyses and in vitro studies
    Chang Yuan, Yilun Li, Xiaolu Yang, Peng Zhang, Xiaolong Li, Li Ma · 2025 · Clinical and Experimental Medicine
  23. Integrative in Silico modeling for mTOR inhibition: From ridge classifiers to descriptor-free deep neural networks
    Seyed Alireza Khanghahi, Hadi Kamkar, Seyedehsamaneh Shojaeilangari, Abdollah Allahverdi, Parviz Abdolmaleki · 2025 · Computer Methods and Programs in Biomedicine Update
  24. GNAZ Regulates PI3K/AKT/mTOR Signaling, Reversing Sorafenib Resistance in Hepatocellular Carcinoma (GNAZ 调节 PI3K/AKT/mTOR 信号传导，逆转肝细胞癌对索拉非尼的耐药性)
    Jian Huang, Xiaomei Chen, Tianxin Luo, Shu Zhang · 2025 · SSRN Electronic Journal
  25. Integrative analysis of polyamine metabolism-related genes in gliomas: implications for prognosis and therapy
    Yujia Zhao, Zhenkai Fu, Sijie Chen, Fei Li, Xiaoyu Zhang, Kaidiriye Setiwalidi, Zhiping Ruan, Yu Yao, Lanxin Luo · 2025 · Frontiers in Oncology
  26. Machine Learning, Virtual Screening and Bioactivity Evaluation to Identify AJ-292/12941271 as an Anti-proliferative Agent and Target mTOR Protein
    Min Li, Yang Yang, Ran Wang, Wufu Zhu, Yuanbiao Tu, Pengwu Zheng, Linxiao Wang · 2025 · Current Medicinal Chemistry
  27. Calcium-directed therapy in acute pancreatitis
    Serge Chooklin, S.S. Chuklin · 2025 · EMERGENCY MEDICINE
  28. Metabolic programming and immune suppression
    Yuanjing Wang, Leina Ma · 2025 · Elsevier eBooks
  29. Genetic alterations and aberrant hormonal pathways in thymic epithelial tumors
    Yuqi Zhang, Wenxin Lian, Wei Zuo, Fufeng Wang, Yaru Zhang, Jing He, Yan Wang, Wen Gao · 2025 · BMC Cancer
  30. A cell-specific computational framework reveals a pan-cancer hypoxia signature predicting overall survival and ICI response
    Caiyu Zhang, Ying Jin, Yifangfei Yu, Yu‐Ling Chen, Jiayi Yang, jialu Zhang, Qianyi Lu, Han Jiang, Yue Sun, Yakun Zhang et al. · 2025 · Journal of Biological Chemistry
  31. Menin-driven mTOR signaling sustains taxane resistance in CRPC and reveals a targetable vulnerability for combination therapy
    İpek Bulut, Buse Cevatemre, Neslihan Yuksel-Catal, Hamzah Syed, Tamer T. Önder, Ceyda Acilan · 2025 · Cell Communication and Signaling
  32. Additional file 1 of The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway
    Hajer Tlili, Anca Macovei, Daniela Buonocore, Manuela Lanzafame, Hanen Najjaa, Anita Lombardi, Andrea Pagano, Maurizia Dossena, Verri, Manuela, Arfa, Abdelkarim Ben et al. · 2021 · Figshare
  33. Additional file 9 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  34. Additional file 2 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  35. Additional file 12 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Xiaomin Li, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  36. Additional file 1 of Network pharmacology and molecular docking analysis on Shenfu Qiangxin indicate mTOR is a potential target to treat heart failure
    Zou, Peilin, Li, Jiajun, Zhang, Yucong, Zonghao Qian, Nie, Hao, Ni Chen Yang, Le Zhang, Li Lin, Peng, Dewei, Zhang, Cuntai · 2024 · Figshare
  37. Additional file 1 of The lncRNA LINC01605 promotes the progression of pancreatic ductal adenocarcinoma by activating the mTOR signaling pathway
    Yuheng Zhu, Jia, Qin-Yuan, Hongfei Yao, Zonghao Duan, Xueshiyu Ma, Zheng, Jia-Hao, Yin, Yi-Fan, Liu, Wei, Zhang, Jun-Feng, Rong Hua et al. · 2024 · Figshare
  38. Additional file 7 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Xiaomin Li, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  39. Additional file 1 of Carbonic anhydrase IX-targeted H-APBC nanosystem combined with phototherapy facilitates the efficacy of PI3K/mTOR inhibitor and resists HIF-1α-dependent tumor hypoxia adaptation
    Liu, Jie, Hu, Xiaochun, Feng, Lei, Lin, Yun, Liang, Shujing, Zhounan Zhu, Shi, Shuo, Dong, Chunyan · 2022 · Figshare
  40. Additional file 1 of MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway
    Su, Wei, Feng, Baijie, Hu, Lina, 郭显智, Yu, Minghua · 2022 · Figshare
  41. Additional file 11 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Xiaomin Li, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  42. Additional file 1 of MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR
    Chang, Xiaowei, Tian, Chang, Jia, Yuanyuan, Cai, Yu, Pu Yan · 2024 · Figshare
  43. Additional file 2 of The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway
    Hajer Tlili, Anca Macovei, Daniela Buonocore, Manuela Lanzafame, Hanen Najjaa, Anita Lombardi, Andrea Pagano, Maurizia Dossena, Verri, Manuela, Arfa, Abdelkarim Ben et al. · 2021 · Figshare
  44. Additional file 3 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Yanfei Shao, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  45. Additional file 1 of TRIM26 inhibits clear cell renal cell carcinoma progression through destabilizing ETK and thus inactivation of AKT/mTOR signaling
    Zheng, Di, Ning, Jinzhuo, Deng, Hao, Yuan Ruan, Cheng, Fan · 2024 · Figshare
  46. Additional file 1 of Six immune-related promising biomarkers may promote hepatocellular carcinoma prognosis: a bioinformatics analysis and experimental validation
    Lin, Xia-Hui, Li, Dong-ping, Liu, Zhi-Yong, Zhang, Si, Tang, Wen-qing, Chen, Rong-xin, 翁书强, Tseng, Yu-jen, 薛如意, Dong, Ling · 2023 · Figshare
  47. Additional file 8 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  48. Additional file 6 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Shao, Yanfei, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  49. Additional file 2 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Yanfei Shao, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  50. Additional file 2 of MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway
    Su, Wei, Feng, Baijie, Hu, Lina, 郭显智, Yu, Minghua · 2022 · Figshare
  51. Additional file 1 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Shao, Yanfei, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  52. Additional file 4 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  53. Additional file 5 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  54. Additional file 3 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  55. Additional file 5 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Shao, Yanfei, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  56. Additional file 6 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  57. Additional file 10 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  58. Additional file 4 of Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
    Wang, Chenxing, Batuer Aikemu, Shao, Yanfei, Zhang, Sen, Guang Yang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua et al. · 2022 · Figshare
  59. Additional file 1 of circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
    Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Qinzi Yuan, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Huaicheng Long et al. · 2022 · Figshare
  60. Single-cell and spatial transcriptomics reveal mTOR-driven cellular fate of spindle cells and immune evasion in classic Kaposi’s sarcoma
    Ting Su, Yongkai Yu, Xuechen Cao, Yidan Wang, Zhonglan Su, Guoxin Song, Lu Sun, Yue Chen, Yan Lu · 2026 · Clinical & Translational Oncology
  61. Targeting one-carbon metabolic vulnerabilities of metastasis with therapeutic potential
    Yanlin Yu, W C Chen, Glenn T Merlino · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Flavonoids as Potential Cardioprotective Agents against Myocarditis
    Jiyun Liu, Na Nie, Yingying Shi, Yan Shen · 2026 · The Natural Products Journal
  63. GSK-J4 Suppresses Tumorigenesis by Targeting the PERK-c-Myc Pathway Through Endoplasmic Reticulum Stress Activation in Tuberous Sclerosis Complex
    Xin Lei, Tao Lang, Ping Li, Changxin Wu · 2026 · International Journal of Molecular Sciences
  64. Targeting metabolism as an approach to treat large B cell lymphoma : lessons learned from anti-metabolic drug combination
    Leonardo Lordello · 2022
  65. L'autophagie, cible thérapeutique potentielle dans les néoplasies myéloprolifératives JAK2V617F
    Charly Courdy · 2022 · theses.fr (ABES)
  66. La fonction suppresseur de tumeur de la protéine adaptatrice SLAP dans le cancer colorectal implique la régulation de la signalisation mTORC2
    Rudy Mevizou · 2021 · theses.fr (ABES)
  67. The role played by MEN1 in breast cancer and the underlying mechanisms : crosstalk between menin, ERα and MYC
    Razan Abou Ziki · 2021
  68. Etudes structurale et fonctionnelle de la protéine Syk dans les cellules B de Leucémie Lymphoïde Chronique
    Souleymane Harouna-Rachidi · 2024 · theses.fr (ABES)
  69. RP11-738E22.3 promotes hepatocellular carcinoma progression by inhibiting autophagy and apoptosis via MAPK/ERK/mTOR pathway
    Yuehua Chen, Erya Hu, Shiqi Tang, Guangzu Cui, Jiayao Ma, Yuanyuan Li, Haicong Liu, Xin Zhou, 彭清平, Da Tang et al. · 2026 · International Journal of Biological Macromolecules
  70. FKBP52 in cancer biology and therapy: molecular mechanisms, signalling networks, and drug targeting of the FKBP protein family
    Ban Qi Tay, Carl P. Soltau, Mark N. Adams, Steven E. Bottle, Derek J. Richard · 2026 · Biochemical Pharmacology
  71. Identification of PRRG1 as a possible molecular target of pancreatic cancer
    Jia-Jie Chen, Xiaoren Zhu, Qian-Hui Gu, Liu Y, Min-Bin Chen · 2026 · Cell Death and Disease
  72. Polyploidy and Senescence of Cancer Cells: Impact of Cell Fusion
    Soham Bhattacharyya, Debopriya Choudhury, Brahmachari Vedeshachaitanya, Pushkar Malakar · 2026 · Advances in experimental medicine and biology
  73. Transcription factor, E4BP4, inhibits autophagy and apoptosis in multiple myeloma and promotes the HDAC3-mediated suppression of the Beclin1 promoter to reduce dexamethasone sensitivity
    Li Li, Mengxing Li, Honglin Liu, Ting Chen, Wenxiu Yang, Weiwei Cheng, Zhongmin Kang, X Y Yang, Ying Luo, Qi Li · 2026 · Journal of Translational Medicine
  74. Multi-omics, organoid-based modeling reveals an SRC/mTOR-dependent fetal-like stem cell trajectory in colorectal cancer
    Theresa Mulholland, Bogac Aybey, Zhenchong Li, Luisa E. Schwarzmüller, Niklas Rindtorff, Lucrezia Tondo, Ping Sui, Ekin Karabati, Philipp Albrecht, Julian E. Riedesser et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  75. Effect of 6-gingerol on proliferation and apoptosis of ovarian cancer cells by the PI3K/AKT/mTOR pathway
    Ai-Ying Guo, Yuehua Chen, Hui Li, Yun-Yun Ren, Xiao-Qing Tan, Xi-Yu Zhang, Jun Xiong · 2026 · Biochemistry and Biophysics Reports
  76. TOMM40 / FADS2 Expression Ratio Predicts the Sensitivity to mTOR Inhibitors in Triple‐Negative Breast Cancer
    Salman Mohamed Farah, Jing‐Quan Zheng, Leon Tsung‐Ju Lee, Hsiao-Wei Lu, Wen-Ke Wang, Chia‐Hao Kuei, Hui-Yu Lin, Hui‐Wen Chiu, Yuan‐Feng Lin · 2026 · Cancer Medicine
  77. 6-Shogaol attenuates cisplatin-induced gastrointestinal inflammation involving modulation of the putative mTOR/TFEB-mediated autophagy-lysosomal pathway
    Wei Zhang, Qingqing Liu, Chenglu Yang, Lei Feng, Yunjing He, Yujie Gao, Yue Wang, Siyu Han, Yarong Zhai, Ke Nie · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
  78. Lower Extremity Overgrowth Associated With a Somatic MTOR Variant
    Michal Ad, Madeleine Givant, Dhruv Singhal, Arin K. Greene · 2026 · Journal of Vascular Anomalies
  79. High-Dose MK-801 Attenuated Early TTC-Defined Cortical Injury Even under the Conditions of Suppressed Rapamycin-Sensitive pS6 Signaling during Early Cerebral Ischemia–Reperfusion
    OAK ZA CHI, Xia Liu, Harvey R. Weiss, Yoon-Seong Kim, Woom‐Yee Bae · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
  80. ERN1 inhibition modifies hypoxic regulation of EGLN1 expression in U87MG glioblastoma cells
    Oleh V. Halkin, Dmytro O. Minchenko, Yuliia M. Viletska, Myroslava Y. Sliusar, Olena O. Khita, Taia V. Feldman, О. H. Minchenko · 2026 · Endocrine Regulations
  81. COVID-19 vaccine-associated autoimmune thyroid eye disease: Graves’ orbitopathy
    Avaniyapuram Kannan Murugan, Rida Afnan, Ali S. Alzahrani · 2026 · Endocrine
  82. Nutraceuticals modulating Wnt/β-catenin and PI3K/mTOR kinase cascades in cancer therapeutics
    Bhavna Bohra, Heena Chauhan, Mithun Singh Rajput, Anshu Srivastava, Ajay Kumar, Bhagawati Saxena · 2026 · Elsevier eBooks
  83. BindingDB Entry 50021146: Targeting autophagy drug discovery: Targets, indications and development trends.
    BindingDB · 2025 · UC San Diego
  84. BindingDB Entry 50015760: The overview of Mitogen-activated extracellular signal-regulated kinase (MEK)-based dual inhibitor in the treatment of cancers.
    BindingDB · 2023 · UC San Diego
  85. BindingDB Entry 50019807: Recent advances in PI3K/PKB/mTOR inhibitors as new anticancer agents.
    BindingDB · 2024 · UC San Diego