Sleep duration is associated with an increased risk for the prevalence of type 2 diabetes in middle-aged women – The FIN-D2D survey
Abstract
Objective To examine the association between sleep duration with type 2 diabetes and abnormal glucose tolerance among middle-aged men and women in Finland.Methods The FIN-D2D survey is a population-based cross-sectional multicentre study in Finland, with 1336 men and 1434 women aged 45-74 participating in the survey during 2004 and 2005. A health examination including an oral glucose tolerance test and sleep questionnaire was performed for all participants.Results There was an independent association between abnormal sleeping times and type 2 diabetes in middle-aged women. Even after adjustments for age, body mass index, sleep apnea probability, smoking, physical activity, and central nervous system-affecting medication, sleep duration of 6h or less or 8h or longer was independently associated with type 2 diabetes. There was no increase in the prevalence of diabetes in middle-aged men with abnormal sleeping times.Conclusion Short (< or = 6h) or long (> or = 8h) sleep duration is related to an increased risk of type 2 diabetes in middle-aged women but not in men.
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Short sleep (fewer than five to six hours) may qualify as an additional clinical factor in the development of insulin resistance and diabetes.
“We suggest that short sleep (fewer than five to six hours) may now qualify as an additional clinical factor in the development of insulin resistance and diabetes, as shown in several cross-sectional studies.27–29”
From Interacting epidemics? Sleep curtailment, insulin resistance, and obesity (2012) · cites this paper as [29]
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References 29 · Cited by 103
- Authors
- Tuomilehto, H., Peltonen, M., Partinen, M., Seppä, J., Saaristo, T., Korpi-Hyövälti, E., Oksa, H., Puolijoki, H., Saltevo, J., Vanhala, M., & Tuomilehto, J.
- Affiliations
- Kuopio University Hospital (FI)
- University of Helsinki (FI)
- Finnish Diabetes Association (FI)
- Tampere University Hospital (FI)
- Central Finland Health Care District (FI)
- Corresponding author
- Tuomilehto, Henri
- Venue
- Sleep Medicine
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 9
- Issue
- 3
- Pages
- 221-227
- ISSN
- 1389-9457 (ISSN-L)
- OpenAlex
- W2153196021
- Cited by
- 103
- References
- 29
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 5 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 7 · 2018: 6 · 2017: 8 · 2016: 4 · 2015: 9 · 2014: 6 · 2013: 8 · 2012: 8
- FWCI
- 8.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sleep Medicine (publishedVersion)
- PubMed (publishedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- sleep duration, type 2 diabetes, impaired glucose tolerance, middle-aged women, sex differences, short sleep duration, long sleep, oral glucose tolerance test
- MeSH terms
- Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Finland, Glucose Tolerance Test, Health Surveys, Humans, Disorders of Excessive Somnolence, Male, Middle Aged, Risk Factors, Sex Factors, Sleep Deprivation
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