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Cited by 327Sleep and related disordersBlood Pressure and Hypertension StudiesObstructive Sleep Apnea Research

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

Epidemiological evidence for the link between sleep duration and high blood pressure: A systematic review and meta-analysis

Guo, Xiaofan, Zheng, Liqiang, Wang, Jun, Zhang, Xiaoyu, Zhang, Xingang, Li, Jue, Sun, Yingxian·2013·Sleep Medicine
DOI 10.1016/j.sleep.2012.12.001
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Abstract

Objectives We aim to assess if the relationship between short or long sleep duration and hypertension is present among adults from epidemiological evidence and to investigate the relationship quantitatively.Methods We performed a comprehensive search of cross-sectional and longitudinal studies using PubMed and the Cochrane Library through February 2012. Our search was supplemented by reviewing reference lists of original and relevant reviews. After the related data were extracted by two investigators independently, pooled odds ratios (ORs) or relative risks (RRs) were estimated using a random-effects model or a fixed-effects model. Publication bias was evaluated, while sensitivity and meta-regression analyses were performed.Results Twenty-four adult studies met our inclusion criteria, with ages ranging from 18 to 106 years. Twenty-one studies involving 225,858 subjects were included in the meta-analysis. The pooled results from the cross-sectional studies showed that short sleep duration was associated with a greater risk for hypertension (OR, 1.21; 95% confidence interval [CI], 1.09-1.34; P<0.001), and long sleep duration also increased the risk for hypertension (OR, 1.11; 95% CI, 1.04-1.18; P=0.003). There was no evidence of publication bias. Pooled analysis from the longitudinal studies indicated a significant association between short sleep duration and hypertension (RR, 1.23; 95% CI, 1.06-1.42; P=0.005), but an insignificant relationship between long sleep duration and hypertension (RR, 1.02; 95% CI, 0.91-1.14; P=0.732). The effects of sleep duration differed by gender, location of the population, and definitions of short or long sleep duration. Meta regression analysis including seven variables did not find the sources of heterogeneity.Conclusions Among adults, a U-shaped relationship between habitual sleep duration and hypertension was found at the cross-sectional level. Short sleep duration was associated with a higher risk for hypertension even longitudinally. We must pay more attention to this lifestyle factor.

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Metadata

Authors
Guo, X., Zheng, L., Wang, J., Zhang, X., Zhang, X., Li, J., & Sun, Y.
Affiliations
  • First Hospital of China Medical University (CN)
  • Sheng Jing Hospital (CN)
  • Tongji University (CN)
Corresponding author
Sun, Yingxian
ORCID
Venue
Sleep Medicine
Publisher
Elsevier BV
Published
2013-04
Volume
14
Issue
4
Pages
324-332
ISSN
1389-9457 (ISSN-L)
DOI
10.1016/j.sleep.2012.12.001
OpenAlex
W1969887065
Cited by
327
References
54
Citations by year
2026: 5 · 2025: 34 · 2024: 30 · 2023: 24 · 2022: 21 · 2021: 31 · 2020: 21 · 2019: 29 · 2018: 27 · 2017: 25 · 2016: 23 · 2015: 21 · 2014: 29 · 2013: 6
FWCI
4.36
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Sleep Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Keywords
sleep duration, hypertension, short sleep duration, long sleep, U-shaped relationship, cardiovascular risk factors, lifestyle factors, adults
MeSH terms
Blood Pressure, Humans, Hypertension, Sleep, Sleep Wake Disorders

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