Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004
Abstract
Detection of hypertension and blood pressure control are critically important for reducing the risk of heart attacks and strokes. We analyzed the trends in the prevalence, awareness, treatment, and control of hypertension in the United States in the period 1999–2004. We used the National Health and Nutrition Examination Survey 1999–2004 database. Blood pressure information on 14 653 individuals (4749 in 1999–2000, 5032 in 2001–2002, and 4872 in 2003–2004) aged ≥18 years was used. Hypertension was defined as blood pressure ≥140/90 mm Hg or taking antihypertensive medications. The prevalence of hypertension in 2003–2004 was 7.3±0.9%, 32.6±2.0%, and 66.3±1.8% in the 18 to 39, 40 to 59, and ≥60 age groups, respectively. The overall prevalence was 29.3%. When compared with 1999–2000, there were nonsignificant increases in the overall prevalence, awareness, and treatment rates of hypertension. The blood pressure control rate was 29.2±2.3% in 1999–2000 and 36.8±2.3% in 2003–2004. The age-adjusted increase in control rate was 8.1% (95% CI: 2.4 to 13.8%; P =0.006). The control rates increased significantly in both sexes, non-Hispanic blacks, and Mexican Americans. Among the ≥60 age group, the awareness, treatment, and control rates of hypertension had all increased significantly ( P ≤0.01). The improvement in blood pressure control is encouraging, although the prevalence of hypertension has not declined.
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Two lower quality studies and five well-done studies (13%, including one at a trend level) reported higher BP in the more R/S or with religious fasting.
“Two lower quality studies [405, 406] and five well-done studies [407–411] (13%, including one at a trend level), however, reported higher BP in the more R/S or with religious fasting.”
From Religion, Spirituality, and Health: The Research and Clinical Implications (2012) · cites this paper as [405]
The Results and Discussion report US hypertension patterns by age, sex, race/ethnicity, and BMI, but do not address religious involvement or fasting. Searches for religious fasting, religiosity, and religion found no passage linking these to higher blood pressure or assessing the cited studies' quality. Page numbers were not available in our copy. (LLM, conf=0.76)
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“The latest National Health and Nutrition Examination Survey reported control rates of 37% in the United States for 2003–2004, with only minor differences between men and women, between whites and blacks and among different age groups.(8) Earlier surveys in the same series reported control rates of 25% for 1990–1994.”
BackgroundInfluentialMcDonald, M., Hertz, R. P., Unger, A. N., & Lustik, M. B. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/gln016 · Cited by 243 · see citing works
Ethnic Differences in Hypertension Incidence Among Middle-Aged and Older Adults
Carson, A. P., Howard, G., Burke, G. L., Shea, S., Levitan, E. B., & Muntner, P. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.168005 · Cited by 245 · see citing works
Ong, K. L., Tso, A. W. K., Lam, K. S. L., & Cheung, B. M. Y. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.105205 · Cited by 243 · see citing works
Self-citationChor, D., Pinho Ribeiro, A. L., Sá Carvalho, M., Duncan, B. B., Andrade Lotufo, P., Araújo Nobre, A., Aquino, E. M. L. L. D., Schmidt, M. I., Griep, R. H., Molina, M. D. C. B., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0127382 · Cited by 239 · see citing works
“In the United States, the excess of high blood pressure shown by Afro-Americans as compared with Whites has been one of the main characteristics of health inequalities[37,53].”
BackgroundResultMikhed, Y., Daiber, A., & Steven, S. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160715918 · Cited by 257 · see citing works
“In humans, the incidence of hypertension, diabetes and atherosclerosis correlates with age (Figure 1A) [26,27].”
BackgroundKrousel-Wood, M. A., Muntner, P., Islam, T., Morisky, D. E., & Webber, L. S. (2009) · Medical Clinics of North America · doi:10.1016/j.mcna.2009.02.007 · Cited by 231 · see citing works
Ong, K. L., Cheung, B. M. Y., Wong, L. Y. F., Wat, N. M. S., Tan, K. C. B., & Lam, K. S. L. (2008) · Annals of Epidemiology · doi:10.1016/j.annepidem.2007.10.007 · Cited by 232 · see citing works
Aronson, S., Dyke, C., Stierer, K. A., Levy, J. H., Cheung, A. T., Lumb, P. D., Kereiakes, D. J., & Newman, M. F. (2008) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e31818240db · Cited by 234 · see citing works
Wong, N. D. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.22.2431 · Cited by 233 · see citing works
Hypertension: Physiology and Pathophysiology
Hall, J. E., Granger, J. P., do Carmo, J. M., da Silva, A. A., Dubinion, J., George, E., Hamza, S., Speed, J., & Hall, M. E. (2012) · Comprehensive Physiology · doi:10.1002/cphy.c110058 · Cited by 232 · see citing works
Barton, M., & Meyer, M. R. (2009) · Hypertension · doi:10.1161/hypertensionaha.108.120022 · Cited by 227 · see citing works
Logan, A. G., Irvine, M. J., McIsaac, W. J., Tisler, A., Rossos, P. G., Easty, A., Feig, D. S., & Cafazzo, J. A. (2012) · Hypertension · doi:10.1161/hypertensionaha.111.188409 · Cited by 210 · see citing works
Cardiovascular Health Disparities
Davis, A. M., Vinci, L. M., Okwuosa, T. M., Chase, A., & Huang, E. S. (2007) · Medical Care Research and Review · doi:10.1177/1077558707305416 · Cited by 215 · see citing works
Cost of poor adherence to anti-hypertensive therapy in five European countries
Mennini, F. S., Marcellusi, A., von der Schulenburg, J. M. G., Gray, A. R., Lévy, P., Sciattella, P., Soro, M., Staffiero, G., Zeidler, J., Maggioni, A. P., et al. (2014) · The European Journal of Health Economics · doi:10.1007/s10198-013-0554-4 · Cited by 217 · see citing works
“The treatment of hypertension, one of the main risk factors, reduces the number of adverse cardiovascular events and thus decreases the economic and health impact of hypertension related CV [4–6].”
BackgroundCaro, J. L. L., Roca, G. C. R., Moreno, F. J. A., Banegas, J. R. B., Alsina, D. G.-S., Arnal, S. L., Divisón, J. A., Ruiz, T. S., Rodríguez, J. A. S., & Alonso, V. B. (2008) · Medicina Clínica · doi:10.1157/13120766 · Cited by 211 · see citing works
Carter, B. L., BERGUS, G. R., Dawson, J. D., Farris, K. B., Doucette, W. R., Chrischilles, E. A., & Hartz, A. J. (2008) · Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2008.07434.x · Cited by 207 · see citing works
Two Self-management Interventions to Improve Hypertension Control
Bosworth, H. B., Olsen, M. K., Grubber, J. M., Neary, A. M., Orr, M. M., Powers, B. J., Adams, M. B., Svetkey, L. P., Reed, S. D., Li, Y., et al. (2009) · Annals of Internal Medicine · doi:10.7326/0000605-200911170-00148 · Cited by 206 · see citing works
Aging, Arterial Stiffness, and Blood Pressure Association in Chinese Adults
Wu, S., Jin, C., Li, S., Zheng, X., Zhang, X., Cui, L., & Gao, X. (2019) · Hypertension · doi:10.1161/hypertensionaha.118.12396 · Cited by 205 · see citing works
Chiang, C., Wang, T., Ueng, K.-C., Lin, T., Yeh, H., Chen, C.-Y., Wu, Y.-J., Tsai, W., Chao, T., Chen, C.-H., et al. (2014) · Journal of the Chinese Medical Association · doi:10.1016/j.jcma.2014.11.005 · Cited by 201 · see citing works
Decreased Slow Wave Sleep Increases Risk of Developing Hypertension in Elderly Men
Fung, M. M., Peters, K. W., Redline, S. S., Ziegler, M. G., Ancoli‐Israel, S., Barrett-Connor, E. L., & Stone, K. L. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.174409 · Cited by 199 · see citing works
Gupte, M., Thatcher, S. E., Boustany, C., Shoemaker, R., Yiannikouris, F. B., Zhang, X., Karounos, M., & Cassis, L. A. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.248559 · Cited by 195 · see citing works
Christian, L. M. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.07.005 · Cited by 193 · see citing works
“However, risk of hypertension is conclusively higher among African Americans in general (Ong et al., 2007), and the chronic stress of minority status is implicated in this link (Brondolo et al., 2008; Brondolo et al., 2003; Cozier et al., 2006; Roberts et al., 2008).”
BackgroundEarly physical activity promotes lower prevalence of chronic diseases in adulthood
Fernandes, R. A., & Zanesco, A. (2010) · Hypertension Research · doi:10.1038/hr.2010.106 · Cited by 193 · see citing works
Ambaw, A. D., Alemie, G. A., Woldeyohannes, S. M., & Mengesha, Z. B. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-282 · Cited by 192 · see citing works
“However, only 37% of hypertensive patients in a 2003-2004 survey were reported to have their blood pressure controlled [6].”
BackgroundJanero, D. R., & Makriyannis, A. (2009) · Expert Opinion on Emerging Drugs · doi:10.1517/14728210902736568 · Cited by 186 · see citing works
“Even highly efficacious cardiovascular drugs have proven insufficient to quench the metabolic syndrome’s negative impact on public health: for example, < 37% of high-blood-pressure patients in the United States attain long-term blood pressure control through antihypertensive therapy [38] .”
BackgroundCastetbon, K., Vernay, M., Malon, A., Salanave, B., Deschamps, V., Roudier, C., Oleko, A., Szego, E., & Herçberg, S. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509274745 · Cited by 187 · see citing works
Triple Antihypertensive Therapy With Amlodipine, Valsartan, and Hydrochlorothiazide
Calhoun, D. A., Lacourcière, Y., Chiang, Y. T., & Glazer, R. D. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.131300 · Cited by 185 · see citing works
Yanes, L. L., & Reckelhoff, J. F. (2011) · American Journal of Hypertension · doi:10.1038/ajh.2011.71 · Cited by 187 · see citing works
“Prostaglandin F(2alpha) metabolite and F(2)isoprostane excretion rates in migraine.”
BackgroundDuration of Lactation and Incidence of Maternal Hypertension: A Longitudinal Cohort Study
Stuebe, A. M., Schwarz, E. B., Grewen, K., Rich-Edwards, J. W., Michels, K. B., Foster, E. M., Curhan, G., & Forman, J. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr227 · Cited by 183 · see citing works
Association between periodontitis and arterial hypertension: a systematic review and meta-analysis
Martin-Cabezas, R., Seelam, N., Petit, C., Agossa, K., Gaertner, S., Tenenbaum, H., Davideau, J.-L., & Huck, O. (2016) · American Heart Journal · doi:10.1016/j.ahj.2016.07.018 · Cited by 183 · see citing works
Resistant hypertension—its identification and epidemiology
Sarafidis, P., Georgianos, P., & Bakris, G. (2013) · Nature Reviews Nephrology · doi:10.1038/nrneph.2012.260 · Cited by 178 · see citing works
Klotho Gene Delivery Prevents the Progression of Spontaneous Hypertension and Renal Damage
Wang, Y., & Sun, Z. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.134320 · Cited by 183 · see citing works
Thethi, T. K., Kamiyama, M., & Kobori, H. (2012) · Current Hypertension Reports · doi:10.1007/s11906-012-0245-z · Cited by 178 · see citing works
The Effects of Insomnia and Sleep Loss on Cardiovascular Disease
Khan, M. S., & Aouad, R. (2017) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2017.01.005 · Cited by 180 · see citing works
Hyre, A. D., Krousel-Wood, M. A., Muntner, P., Kawasaki, L., & DeSalvo, K. B. (2007) · Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2007.06372.x · Cited by 174 · see citing works
Choi, H. M., Kim, H. C., & Kang, D. R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178334 · Cited by 174 · see citing works
Vitamin D deficiency and risk of cardiovascular diseases: a narrative review
Kheiri, B., Abdalla, A., Osman, M., Ahmed, S. A., Hassan, M., & Bachuwa, G. I. (2018) · Clinical Hypertension · doi:10.1186/s40885-018-0094-4 · Cited by 174 · see citing works
Differences in sleep between black and white adults: an update and future directions
Petrov, M. E. R., & Lichstein, K. L. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.01.011 · Cited by 173 · see citing works
“Second, the assumption of treatment access and consistency across different ethnicities has proven untenable in multiple other domains such as hypertension and chronic pain [70,71].”
BackgroundDeFilippis, A. P., Young, R. L., McEvoy, J. W., Michos, E. D., Sandfort, V., Kronmal, R. A., McClelland, R. L., & Blaha, M. J. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw301 · Cited by 169 · see citing works
Epidemiology of hypertensive kidney disease
Udani, S., Lazich, I., & Bakris, G. L. (2011) · Nature Reviews Nephrology · doi:10.1038/nrneph.2010.154 · Cited by 171 · see citing works
“An analysis of data from the 1999–2004 National Health and Nutrition Examination Survey (NHANES) found that the prevalence of hypertension in the USA increased over these 5 years; prevalence rates were approximately 27% in 1999 and 29% in 2004”
MethodRao, M. V., Qiu, Y., Wang, C., & Bakris, G. L. (2008) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2007.12.012 · Cited by 168 · see citing works
Isolated Systolic Hypertension in the Elderly
Chobanian, A. V. (2007) · New England Journal of Medicine · doi:10.1056/nejmcp071137 · Cited by 162 · see citing works
Son, P. T., Quang, N. N., le Viet, N., Khai, P. G., Wall, S., Weinehall, L., Bonita, R., & Byass, P. (2011) · Journal of Human Hypertension · doi:10.1038/jhh.2011.18 · Cited by 166 · see citing works
Adane, A. A., Awoke, T., Alemu, S., & Zeleke, B. M. (2012) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-12-113 · Cited by 164 · see citing works
“3% prevalence report from the United States [10].”
BackgroundBlumenthal, J. A., Babyak, M. A., Sherwood, A., Craighead, L. W., Lin, P., Johnson, J. J., Watkins, L. L., Wang, J. T., Kuhn, C. M., Feinglos, M. N., et al. (2010) · Hypertension · doi:10.1161/hypertensionaha.109.149153 · Cited by 163 · see citing works
Predictors of Decline in Medication Adherence
Krousel-Wood, M. A., Joyce, C., Holt, E. W., Muntner, P., Webber, L. S., Morisky, D. E., Frohlich, E. D., & Ré, R. N. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.176859 · Cited by 159 · see citing works
Genetic Variation and Adaptation in Africa: Implications for Human Evolution and DiseasePreprint
Gomez, F., Hirbo, J. B., & Tishkoff, S. A. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008524 · Cited by 160 · see citing works
“In the United States, diseases like type 2 diabetes mellitus, hypertension, and prostate cancer are known to be more common in African Americans than European Americans (Landis et al. 1999; Brancati et al. 2000; Ong et al. 2007).”
BackgroundTemporal Trends in the Population Attributable Risk for Cardiovascular Disease
Cheng, S. C., Claggett, B. L., Correia, A. W., Shah, A. M., Gupta, D. K., Skali, H., Ni, H., Rosamond, W. D., HEISS, G. M., Folsom, A. R., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.008506 · Cited by 159 · see citing works
- Authors
- Ong, K. L., Cheung, B. M. Y., Man, Y. B., Lau, C. P., & Lam, K. S. L.
- Affiliations
- University of Hong Kong (HK)
- Venue
- Hypertension
- Published
- 2007-01
- Volume
- 49
- Issue
- 1
- Pages
- 69-75
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2122326747
- Cited by
- 1,395
- References
- 35
- Citations by year
- 2026: 1 · 2025: 8 · 2024: 18 · 2023: 29 · 2022: 25 · 2021: 34 · 2020: 35 · 2019: 39 · 2018: 44 · 2017: 53 · 2016: 55 · 2015: 66 · 2014: 77 · 2013: 103 · 2012: 106
- FWCI
- 98.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- hypertension prevalence, hypertension awareness, antihypertensive therapy, blood pressure control, temporal trends, age differences, racial and ethnic differences, non-Hispanic blacks, Mexican Americans, adults
- MeSH terms
- Adult, Aging, Black or African American, Blood Pressure, Female, Goals, Humans, Hypertension, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Nutrition Surveys, United States, Prevalence, Mexican Americans, Black People
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