The DOI matches its Crossref record; 105 of the 106 references it cites were found in a registry or an index.
Who are the long sleepers? Towards an understanding of the mortality relationship
Open accessAbstract
While much is known about the negative health implications of insufficient sleep, relatively little is known about risks associated with excessive sleep. However, epidemiological studies have repeatedly found a mortality risk associated with reported habitual long sleep. This paper will summarize and describe the numerous studies demonstrating increased mortality risk associated with long sleep. Although these studies establish a mortality link, they do not sufficiently explain why such a relationship might occur. Possible mechanisms for this relationship will be proposed and described, including (1) sleep fragmentation, (2) fatigue, (3) immune function, (4) photoperiodic abnormalities, (5) lack of challenge, (6) depression, or (7) underlying disease process such as (a) sleep apnea, (b) heart disease, or (c) failing health. Following this, we will take a step back and carefully consider all of the historical and current literature regarding long sleep, to determine whether the scientific evidence supports these proposed mechanisms and ascertain what future research directions may clarify or test these hypotheses regarding the relationship between long sleep and mortality.
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“Further, although some studies have suggested potential reasons why longer sleep durations may be harmful,114 the panel was unable to come to a consensus regarding biologically plausible pathways by which long sleep could explicitly cause poor health (acknowledging that biological plausibility depends on knowledge available at the time).”
In the citing paper
“Also, there is still a lack of clarity on the biological plausibility of the long sleep relationship, although some ideas have been proposed.37,38”
From Sleep, Health, and Society (2017) · cites this paper as [38]
Citations
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O'Connell, S. E. (2013) · Loughborough University Institutional Repository (Loughborough University)
Metadata
- Authors
- Grandner, M. A., & Drummond, S. P. A.
- Affiliations
- San Diego State University (US)
- University of California San Diego (US)
- Corresponding author
- Grandner, Michael A.
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2007-10
- Volume
- 11
- Issue
- 5
- Pages
- 341-360
- ISSN
- 1087-0792 (ISSN-L)
- PMC
- PMC3755488
- OpenAlex
- W1987857642
- Cited by
- 432
- References
- 106
- Citations by year
- 2026: 16 · 2025: 28 · 2024: 25 · 2023: 43 · 2022: 33 · 2021: 39 · 2020: 33 · 2019: 24 · 2018: 26 · 2017: 27 · 2016: 25 · 2015: 24 · 2014: 15 · 2013: 32 · 2012: 10
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Sleep Medicine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (T32HL007713)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- long sleep, excessive sleep, mortality risk, sleep duration, sleep fragmentation, fatigue, immune function, depression, sleep apnea, heart disease
- MeSH terms
- Depression, Fatigue, Female, Health Status, Heart Diseases, Humans, Male, Risk Factors, Sleep, Sleep Apnea Syndromes, Sleep Wake Disorders, Sleep Stages, Comorbidity
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