Cited by 511Sleep and related disordersSleep and Wakefulness ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 157 of the 158 references it cites were found in a registry or an index.

Sleep and anxiety: From mechanisms to interventions

Chellappa, Sarah L., Aeschbach, Daniel·2022·Sleep Medicine Reviews

DOI 10.1016/j.smrv.2021.101583

Open this paper in CoChat — free account

Abstract

Anxiety is the most common mental health problem worldwide. Epidemiological studies show that sleep disturbances, particularly insomnia, affect ∼50% of individuals with anxiety, and that insufficient sleep can instigate or further exacerbate it. This review outlines brain mechanisms underlying sleep and anxiety, by addressing recent human functional/structural imaging studies on brain networks underlying the anxiogenic impact of sleep loss, and the beneficial effect of sleep on these brain networks. We discuss recent developments from human molecular imaging studies that highlight the role of specific brain neurotransmitter mechanisms, such as the adenosinergic receptor system, on anxiety, arousal, and sleep. This review further discusses frontline sleep interventions aimed at enhancing sleep in individuals experiencing anxiety, such as nonbenzodiazepines/antidepressants, lifestyle and sleep interventions and cognitive behavioral therapy for insomnia. Notwithstanding therapeutic success, up to ∼30% of individuals with anxiety can be nonresponsive to frontline treatments. Thus, we address novel non-invasive brain stimulation techniques that can enhance electroencephalographic slow waves, and might help alleviate sleep and anxiety symptoms. Collectively, these findings contribute to an emerging biological framework that elucidates the interrelationship between sleep and anxiety, and highlight the prospect of slow wave sleep as a potential therapeutic target for reducing anxiety.

Integrity signals

Registry

Crossref · 10.1016/j.smrv.2021.101583

Cites

157 of 157 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
(2012) · Springer eBooks · doi:10.1007/springerreference_121117 · Cited by 20,772
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
James, S. L., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdela, J., Abdelalim, A., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32279-7 · Cited by 13,867
Large-scale brain networks and psychopathology: a unifying triple network model
Menon, V. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.08.003 · Cited by 4,168
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.83 · Cited by 2,083
European guideline for the diagnosis and treatment of insomnia
Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., Espie, C. A., Garcia‐Borreguero, D., Gjerstad, M., Gonçalves, M., et al. (2017) · Journal of Sleep Research · doi:10.1111/jsr.12594 · Cited by 2,049
Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians
Qaseem, A., Kansagara, D., Forciea, M. A., Cooke, M., Denberg, T. D., & for the Clinical Guidelines Committee of the American College of Physicians* (2016) · Annals of Internal Medicine · doi:10.7326/m15-2175 · Cited by 1,965
A Multidimensional Meta-Analysis of Psychotherapy for PTSD
Bradley, R., Greene, J., Russ, E., Dutra, L., & Westen, D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.2.214 · Cited by 1,938
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults
Breslau, N., Roth, T., Rosenthal, L., & Andreski, P. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00188-3 · Cited by 1,831

Show all 158 references

Research works printed but not linked: 2

Alonso, 2007, Overview of key data from the European study of the epidemiology of mental disorders (ESEMeD), J Clin Psychiatr, 68, 3
Duval, 2015, Neural circuits in anxiety and stress disorders: a focused review, Therapeut Clin Risk Manag, 11, 115

Sorted by citations

Items 101–200 of 511

Bridge symptoms of insomnia, obsessive-compulsive symptoms, and depression/anxiety: a network analysis
Yuan, S., Wang, R., Shi, Y., Zhao, Y., Tao, H., Wu, G., Tan, L., & Ouyang, X. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06998-8 · Cited by 14
“Contrastingly, insomnia has been shown to have a bidirectional relationship with both depression [24] and anxiety, with these conditions affecting each other [25].”
Effect of duloxetine on pain and opioid consumption after total knee and hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials
Zhong, H., Li, J., Chen, Y., Huang, Y., Wen, Z., & Zhao, J. (2023) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-023-01593-x · Cited by 9
“Adequate sleep can relieve stress and unnecessary anxiety [37].”
Resilience predicts and modulates anxiety severity in people with epilepsy
Assenza, G., Sancetta, B. M., Lanzone, J., Narducci, F., Ricci, L., Boscarino, M., Marrelli, A., Ciuffini, R., Piccioli, M., Lazzaro, V. D., et al. (2023) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2023.109390 · Cited by 8
Timing of Deep and REM Sleep Based on Fitbit Sleep Staging in Young Healthy Adults under Real-Life Conditions
von Gall, C., Holub, L., Ali, A. A. H., & Eickhoff, S. B. (2024) · Brain Sciences · doi:10.3390/brainsci14030260 · Cited by 8
Wavelet Entropy Analysis of Electroencephalogram Signals During Wake and Different Sleep Stages in Patients with Insomnia Disorder
Yang, Q., Liu, L., Wang, J., Zhang, Y., Jiang, N., & Zhang, Y. (2024) · Nature and Science of Sleep · doi:10.2147/nss.s452017 · Cited by 9
Unraveling the relationship between facial neuropathic conditions and pain, sleep, chronotypes, bruxism, and psychosocial factors
Souza, R., Gandara, C., Serra‐Negra, J. M., & Almeida‐Leite, C. M. (2025) · CRANIO® · doi:10.1080/08869634.2025.2449595 · Cited by 8
“This is in accordance with literature showing that anxiety is associated with a great variety of sleep disorders [70,71], which may be even more important in a chronic pain population.”
Home Environment as a Therapeutic Target for Prevention and Treatment of Chronic Diseases: Delivering Restorative Living Spaces, Patient Education and Self-Care by Bridging Biophilic Design, E-Commerce and Digital Health Technologies
Huntsman, D. D., & Bulaj, G. W. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22020225 · Cited by 11
“Given the sleep–anxiety relationship, it is important to optimize the bedroom to simultaneously improve sleep quality and reduce anxiety symptoms [230].”
Medicinal cannabis in the management of anxiety disorders: A systematic review
Roberts, L., Sorial, E., Budgeon, C. A., Lee, K., Preen, D. B., & Cumming, C. (2025) · Psychiatry Research · doi:10.1016/j.psychres.2025.116552 · Cited by 11
“Additionally, studies have shown significant associations between poor sleep quality and anxiety-related disorders beyond PTSD, underscoring the critical role of addressing sleep disturbances in effectively managing anxiety disorders (Alvaro et al., 2013; Chellappa and Aeschbach, 2022).”
Impact of resistance training on sleep quality, mental health, and functional capacity in older women with varying baseline sleep quality: A randomized controlled trial
Cunha, P. M., dos Santos, L., Herold, F., Castro-E-Silva, P., Chen, Y., Wang, Y., Santos-Melo, V., Cavalcante, E. F., Lima, L., de Souza, S. C., et al. (2025) · Psychology of sport and exercise · doi:10.1016/j.psychsport.2025.102968 · Cited by 8
Ultrasound-Guided Stellate Ganglion Block with Cervicotemporal Myofascial Trigger Point Acupuncture for Insomnia with Comorbid Anxiety and Depression: A Retrospective Observational Study
Li, Z., Wang, L., Cong, P., Chen, S., Wang, J., Zhang, H., Zhao, J., Li, G., Jiao, F., Li, L., et al. (2025) · Nature and Science of Sleep · doi:10.2147/nss.s551748 · Cited by 9
Relationships Between Sleep Quality, Anxiety and Depression in University Students: Stable Trends over Time and a Pronounced Concern for Sleep Initiation
Whitehead, J. P., & Horton, C. L. (2025) · Brain Sciences · doi:10.3390/brainsci15111142 · Cited by 11
“[6] and neurodiverse groups ( ≤ 80”
Multiplatform-Integrated Identification of Melatonin Targets for a Triad of Psychosocial-Sleep/Circadian-Cardiometabolic Disorders
Campos, L. A., Baltatu, O. C., Senar, S., Ghimouz, R., Alefishat, E. A., & Cipolla‐Neto, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24010860 · Cited by 8
“As a consequence of psychological stress, anxiety and depression produce a cascade of pathological responses that implicate melatonin and cause sleep abnormalities [33,34] and circadian rhythm disturbances [6,35].”
Background
Sleep outcomes and related factors in Parkinson’s disease after subthalamic deep brain electrode implantation: a retrospective cohort study
Ma, R., Yin, Z., Chen, Y., Yuan, T., An, Q., Gan, Y., Xu, Y., Jiang, Y., Du, T., Yang, A., et al. (2023) · Therapeutic Advances in Neurological Disorders · doi:10.1177/17562864231161163 · Cited by 9
Associations between perioperative sleep patterns and clinical outcomes in patients with intracranial tumors: a correlation study
Liu, Y., Wu, F., Zhang, X., Jiang, M., Zhang, Y., Wang, C., Sun, Y., & Wang, B. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1242360 · Cited by 8
“Suﬃcient sleep time assists in regulating the balance of neurotransmitters such as dopamine, glutamate, serotonin, and adenosine to prevent anxiety (46).”
Mitochondrial dysfunction following repeated administration of alprazolam causes attenuation of hippocampus-dependent memory consolidation in mice
Zhu, S., Shi, J., Jin, Q., Zhang, Y., Zhang, R., Chen, X., Wang, C., Shi, T., & Li, L. (2023) · Aging · doi:10.18632/aging.205087 · Cited by 8
Sleep quality and mental health among Chinese nurses after the COVID-19 pandemic: A moderated model
Zhao, Y., Liu, F., Lin, P., Tu, Z., & Wu, B. (2024) · PLoS ONE · doi:10.1371/journal.pone.0295105 · Cited by 8
Sleep quality as a mediator of the relationship between screen time and negative emotions among Chinese college freshmen
Lu, H., Liang, G., Li, D., Liu, M.-X., Yin, Z.-J., Li, Y.-Z., Zhang, T., & Pan, C.-W. (2023) · Psychology Health & Medicine · doi:10.1080/13548506.2023.2217380 · Cited by 8
“Sleep loss may reduce dopamine D2/D3 receptor availability in the ventral striatum, causing dopaminergic hypoactivity and anxiety symptoms (Berry et al., 2019; Chellappa & Aeschbach, 2022).”
Background
Insomnia and anxiety among COVID-19 patients in China: the chain mediating effect of psychological capital and self-esteem
Du, J., Wu, C., Zheng, W., Cui, S.-N., Li, L., Liu, Z., Gao, L., Heng, C., & Lang, H. (2024) · BMC Nursing · doi:10.1186/s12912-023-01563-8 · Cited by 8
“Epidemiological studies have shown that about 50% of people with anxiety disorders were affected by sleep disorders, especially insomnia, which could be triggered or further exacerbated by sleep deprivation [5].”
Background
A federated semi-supervised automatic sleep staging method based on relationship knowledge sharing
Ma, B., Duan, L., Huang, Z., Qiao, Y., & Gong, B. (2023) · Expert Systems with Applications · doi:10.1016/j.eswa.2023.121427 · Cited by 7
Clinical effectiveness of internet-based cognitive behavioral therapy for insomnia in routine secondary care: results of a randomized controlled trial
Pchelina, P. V., Poluektov, M. G., Krieger, T., Duss, S. B., & Berger, T. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1301489 · Cited by 8
The effects of shared, depression-specific, and anxiety-specific internalizing symptoms on negative and neutral episodic memories following post-learning sleep
Niu, X., Utayde, M. F., Sanders, K. E. G., Cunningham, T. J., Zhang, G., Kensinger, E. A., & Payne, J. D. (2024) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-024-01209-5 · Cited by 8
“…sleep may provide robust passive protection against daytime interferences (Casillas & Clark, 2000), especially during SWS where slow oscillatory activities may offer ameliorating benefits on anxious thoughts and cognitive disruptions (Ben Simon et al., 2020; Chellappa & Aeschbach, 2022).”
Impacts of human behaviors involving sound and light exposure in sleep environments on sleep and mental disorders: A cross-sectional study
Hu, L., Dai, X., Fang, X., Su, K., Wang, C., Yang, C., Zhang, R., He, J., Li, M., Ye, X., et al. (2024) · Building and Environment · doi:10.1016/j.buildenv.2024.112211 · Cited by 7
Maternal and paternal harsh parenting and anxiety symptoms in Chinese adolescents: examining a multiple mediation model
Yang, X., Lin, L., Feng, W., Liu, P., Liang, N., Xue, Z., Ma, Y., Shen, Y., Yu, W., Lu, J., et al. (2024) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-024-00826-9 · Cited by 10
“…that sleep problems can alter brain network activity, including the limbic system and cognitive con-trol networks (e.g., the dorsal anterior cingulate cortex and the anterior insula) as well as the regulation of neurotransmitter systems and emotional processing, which may heighten anxiety [59].”
Background
Exploring the link between comorbid insomnia and sleep apnea (COMISA) and erectile dysfunction: implications for male sexual health
Andersen, M. L., Gozal, D., & Tufik, S. (2024) · Sexual Medicine Reviews · doi:10.1093/sxmrev/qeae068 · Cited by 7
Treatment of Insomnia With Traditional Chinese Medicine Presents a Promising Prospect
Zhang, B., Wang, Q., Zhang, Y., Wang, H., Kang, J., Zhu, Y., Wang, B., & Feng, S. (2025) · Phytotherapy Research · doi:10.1002/ptr.8495 · Cited by 9
“Norepinephrine (NE), dopamine (DA), and histamine are primarily associated with promoting arousal, while serotonin (5-hydroxytryptamine, 5-HT) exerts more complex, bi-directional effects on sleep (Chellappa and Aeschbach 2022; Cespuglio 2018; Van Egroo et al. 2022).”
Negative impact of insufficient sleep on the brain
Cao, Q., Xiang, H., Wang, Y., Liu, F., Weng, X., & Xu, F. (2025) · Brain-Apparatus Communication A Journal of Bacomics · doi:10.1080/27706710.2025.2465538 · Cited by 11
Trifluoperazine improves postoperative cognition by influencing astrocyte endfoot morphology and aquaporin-4 polarity
Chen, C., Zhu, B., Luo, W., Cao, A., Zhou, W., Weng, Y., & Wang, J. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05072-4 · Cited by 7
“It was also interesting to observe that pretreatment of the mice with 2 mg/kg TFP alleviated postoperative anxiety-like behavior, as perioperative sleep deprivation is closely related to anxiety [45].”
Dysfunctional sleep beliefs and sleep quality among Chinese university students: the mediating roles of depression, anxiety, and stress
Wang, P., Xie, C., Qian, J., Cai, S., Xu, L., Jiang, X., Chen, G., & Wang, K. (2025) · BMC Psychology · doi:10.1186/s40359-025-03210-0 · Cited by 7
“…with higher levels of anxiety are more prone to sleep problems, possibly because anxiety disrupts the balance of neurotransmitters in the brain, particularly the cholinergic system, GABA system, and the functioning of serotonin and melatonin—key substances for the stability of the sleep cycle [73].”
Bifidobacterium longum supplementation prevents intestinal inflammation and cognitive impairment in sleep-deprived mice by modulating clock gene expression
Huang, L., Li, X., Guo, M., Lu, W., Zhao, J., Xiao, Y., & Chen, W. (2025) · Food & Function · doi:10.1039/d5fo02921j · Cited by 7
Understanding the relationship between sleep, psychological and musculoskeletal health from a neuroimmune perspective
Klyne, D. M., Hall, M., Smith, S. S., Barbe, M. F., Egorova, N., Serafimovska, A., Hodges, P. W., & Suraev, A. S. (2026) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2026.103509 · Cited by 9
A scale to measure the worry level in Gastrointestinal Endoscopy with sedation: Development, reliability, and validity
Yu, X., Deng, H., Xiong, Z., Gong, P., Ye, M., Liu, T., Long, X., & Tian, L. (2023) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2023.100410 · Cited by 8
The effect of anxiety on sleep disorders in medical students: a moderated mediation model
Yu, C., Liu, Z., Su, T., Li, Z., Jiang, Z., Zhong, W., & Xiao, Z. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1338796 · Cited by 7
“To date, research studies have shown that anxiety and neuroticism interfere with sleep (Chellappa and Aeschbach, 2022).”
Background
SGLT2 inhibition, circulating proteins, and insomnia: A mendelian randomization study
Luo, J., Tu, L., Zhou, C., Li, G., Shi, L., & Hu, S. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.05.036 · Cited by 8
The effect of prebiotic and probiotic food consumption on anxiety severity: a nationwide study in Korea
Tae, H., & Kim, T. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1385518 · Cited by 7
“Anxiety disorder appears to be highly prevalent globally (1).”
Background
Circadian Synchronization of Feeding Attenuates Rats’ Food Restriction-Induced Anxiety and Amygdalar Thyrotropin-Releasing Hormone Downregulation
Soberanes-Chávez, P., Trujillo-Barrera, J., & de Gortari, P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115857 · Cited by 7
“…with obesity due to different factors, such as disruptions of eating habits [3,4] with consequent alterations in their sleep/awake patterns [5,6], high-fat diet-induced neuroinflammation [7,8], and high stress levels provoked by caloric restriction dieting (CRD) [9], which is the most…”
Background
Gray matter volume alterations in de novo Parkinson's disease: A mediational role in the interplay between sleep quality and anxiety
He, G., Huang, X., Sun, H.-H., Xing, Y., Gu, S., Ren, J., Liu, W., & Lu, M. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14867 · Cited by 7
Insomnia symptoms as long-term predictors of anxiety symptoms in middle-aged and older adults from the English Longitudinal Study of Ageing (ELSA), and the role of systemic inflammation
Zagaria, A., & Ballesio, A. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.09.020 · Cited by 11
An explainable predictive model for anxiety symptoms risk among Chinese older adults with abdominal obesity using a machine learning and SHapley Additive exPlanations approach
Niu, T., Cao, S., Cheng, J., Zhang, Y., Zhang, Z., Xue, R., Ma, J., Ran, Q., & Xian, X. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1451703 · Cited by 7
CaMKIIa Neurons of the Ventromedial Hypothalamus Mediate Wakefulness and Anxiety-like Behavior
Li, Y., Li, Y., Zhang, X., Li, Y., Liu, Y., & Xu, H. (2023) · Neurochemical Research · doi:10.1007/s11064-023-03925-9 · Cited by 7
“This mental state is accompanied with the occurrence of anxiety-related behaviors as well as defensive behaviors that presuppose heightened arousal and the ability to make a rapid transition from sleep to wakefulness [3, 7, 8, 37, 38], which is essential for animals to take timely and successful action against potenti…”
Background
The impact of green tea and its bioactive compounds on mood disorder symptomology and brain derived neurotrophic factor: a systematic review of randomized controlled trials
Cavanah, A. M., Robinson, L. A., Mattingly, M. L., & Frugé, A. D. (2025) · Biomedicines · doi:10.3390/biomedicines13071656 · Cited by 7
Efficacy and safety of multiple external therapies in patients with insomnia: a systematic review and network meta-analysis
Wang, Z., Xu, H. G., Wang, Z., Zhou, H., Zhang, L., Wang, Y., Li, M., & Zhou, Y. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1297767 · Cited by 6
“Some studies have shown that the relationship between insomnia and depression and anxiety is bidirectional and that improvements in poor psychological states can also affect the effectiveness of insomnia treatment (125, 126).”
Background
Cognitive function, sleep characteristics and their relationship in older adults with insomnia and anxiety
Jia, W. P., Zeng, J. K., & Qi, R. B. (2025) · Scientific Reports · doi:10.1038/s41598-025-16228-6 · Cited by 6
“Previous studies have found that the higher the anxiety level, the more serious the sleep disorder 8 .”
Exploring the Impact and Mechanisms of Coffee and Its Active Ingredients on Depression, Anxiety, and Sleep Disorders
Shi, Z., Luan, J., Zhang, Y., Wang, G., Mei, C., Chen, L., Zhou, W., Xiong, C., Huang, T., Zhan, J., et al. (2025) · Nutrients · doi:10.3390/nu17193037 · Cited by 9
“…most common mental health problems worldwide, affecting approximately 25% of the global population, which is characterized by excessive and persistent feelings of fear and worry, that are disproportionate to the actual threats faced, leading to impairment in the patient’s daily life functions [4].”
Sleep quality during pregnancy: the role of anxiety, fear of childbirth, and obstetric factors – a multicenter cross-sectional study
Banaei, M., Alizadeh, S., Roozbeh, N., Naz, M. S. G., Taghvaei, E., Parviz, L., & Ghasemi, V. (2025) · BMC Public Health · doi:10.1186/s12889-025-25142-5 · Cited by 6
“In addition, the relationship between anxiety and sleep quality is bidirectional: high levels of anxiety often lead to poor sleep quality and insomnia, whereas poor sleep quality can, in turn, increase anxiety [34].”
Relationship between bedtime, nighttime sleep duration, and anxiety symptoms in preschoolers in China
Qiu, S.-Y., Yin, X., Yang, Y., Li, T., Lu, D., Li, J., Yang, W., Wen, G., Zhang, J., Zhang, Y., et al. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1290310 · Cited by 6
Acupressure: a possible therapeutic strategy for anxiety related to COVID-19: a meta-analysis of randomized controlled trials
Peng, Z., Zheng, Y., Yang, Z., Zhang, H., Li, Z., Xu, M., Cui, S., & Lin, R. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1341072 · Cited by 6
“The etiology and pathogenesis of anxiety disorder are complex, believed to involve a variety of factors including genetics, neurobiochemistry, neuroimaging, sex hormones, constitution and other reasons (55–57).”
Background
The association between diet and sleep with internalising symptoms in young athletes: a serial multiple mediation models
Gao, Y., & Wang, L. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1382068 · Cited by 7
“Moreover, the relationship between sleep and anxiety may be explained by shared neurocircuity and there is a complex network of receptor systems, including dopamine, serotonin and adenosine (62).”
Background
Restless sleep is associated with increased anxiety in physical therapy students: a cross sectional survey study
Shepherd, M. H., Neilson, B. D., Siengsukon, C. F., & Young, J. L. (2024) · BMC Medical Education · doi:10.1186/s12909-024-06140-4 · Cited by 7
“Specifically, insufficient sleep increases activity in neural networks related to fear and disrupts neural networks related to cognitive control [29].”
BackgroundInfluential
Chronic insomnia – beyond the symptom of insufficient sleep
Georgiev, T., Draganova, A. I., Avramov, K., & Terziyski, K. V. (2025) · Folia Medica · doi:10.3897/folmed.67.e151493 · Cited by 9
“[18,31] Evidence suggests that CI could be considered as causative factor for anxiety, thereby measures for insomnia prevention are expected to ameliorate anxiety symptoms and improve therapeutic outcome.”
Prevalence and Risk Factors of Anxiety Among Adult Patients with Chronic Pharyngitis in Wuhu, China
Zha, Z.-H., Gao, S., Liu, S.-F., & Hu, G.-Q. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s415938 · Cited by 3
“Anxiety, a psychological and physiological condition characterized by strong feelings of worry, unease, or fear that interfere with work and daily life, is the most common mental health problem worldwide.(7) Due to the long course of CP, difficulty in self healing, complex etiology, multiple complications, and high tr…”
Case report: Diagnosis and intervention of a non-24-h sleep–wake disorder in a sighted child with a psychiatric disorder
Estivill, C., Rodríguez-Morilla, B., Estivill, E., & Madrid, J. A. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1129153 · Cited by 6
Is it Time to Include Wearable Sleep Trackers in the Applied Psychologists’ Toolbox?
Menghini, L., Balducci, C., & de Zambotti, M. (2024) · The Spanish Journal of Psychology · doi:10.1017/sjp.2024.8 · Cited by 7
Sleep deprivation increases the generalization of perceptual and concept-based fear: An fNIRS study
Zhang, J., Wang, J., Wang, Y., Zhang, D., Li, H., & Lei, Y. (2024) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2024.102892 · Cited by 8
Effects of perceived sleep quality on creative behavior via work engagement: the moderating role of gender
Wang, W., Jeung, W., Kang, S., & Kim, H. J. (2024) · BMC Psychology · doi:10.1186/s40359-024-01971-8 · Cited by 8
“In contrast, poor sleep quality is associated with heightened anxiety and stress levels [37], which can deplete cognitive resources and hinder individuals’ creative behavior [28].”
Background
The Efficacy of Non‐Pharmacological Interventions for Sleep Disorders in People With Multiple Sclerosis: A Systematic Review and Meta‐Analysis
Özdoğar, A. T., & Kalron, A. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70084 · Cited by 5
“…it may enhance prefrontal regulation of stress, reduce amygdala hyperactivity, and support stress management in the anterior cingulate cortex, potentially mitigating hyperarousal that disrupts sleep (Yang et al. 2018; Chellappa and Aeschbach 2022; Desbordes et al. 2012; Palmer and Alfano 2017).”
Machine Learning Models to Identify Clinically Significant Anxiety in Short‐Term Insomnia Using Accelerometers
Fang, L., Zeng, W., Zheng, S., Du, S., Yang, H., Luo, X., Zeng, S., Huang, Z., Chen, W., & Zhang, B. (2025) · Depression and Anxiety · doi:10.1155/da/3082856 · Cited by 7
“For example, disruptions in serotonin levels can lead to CSA [50, 51], whereas ﬂ uctuations in dopamine can impair cognitive processes such as attention and memory [52, 53].”
The mediating role of sleep quality on the relationship between physical activity and social anxiety disorder among Chinese college freshmen
Liu, Y., Nie, Z., Dong, H., Shou, L., Xu, J., Cao, Q., Shi, Y., Wu, C., Zhang, M., Yang, J., et al. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1599041 · Cited by 7
“The potential mechanism involved may be related to the role of speciﬁc brain neurotransmitter, such as the adenosinergic receptor system, in regulating anxiety, arousal, and sleep (Chellappa and Aeschbach, 2022).”
Prophylactic Effect of Prefrontal Alternating Current Stimulation on Postoperative Sleep Disturbance in Patients Undergoing Gynecological Laparoscope: A Randomized, Double‐Blind, Sham‐Controlled Trial
Du, N., Yang, J., Li, X., Li, Z., Hashimoto, K., Lei, L., & Yang, J. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70529 · Cited by 5
“…on the neural mechanisms underlying this complex interplay, highlighting the role of functional connectivity among key brain regions—such as the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, precuneus, amygdala, and insula— in modulating the sleep- anxiety-depression nexus [34, 35].”
Electrochemistry as a Tool for Redox‐Based Bio‐Information Processing
Kim, E., Chen, C., Zakaria, F. R., Motabar, D., Kang, M., Kelly, D. L., Napolitano, A., Bentley, W. E., & Payne, G. F. (2025) · Advanced Science · doi:10.1002/advs.202510184 · Cited by 5
How exercise adherence affects emotion regulation in Chinese college students: The chain mediating effect of sleep quality and self-efficacy
Wang, G., Wang, Z., Mu, F.-Z., Li, G., & Li, B. (2026) · PLoS ONE · doi:10.1371/journal.pone.0338572 · Cited by 5
“Sleep deprivation impairs emotion regulation capacity and amplifies negative affect [81], including significant executive function decline [80,82], Insomnia exhibits high comorbidity with depression and anxiety.”
Insomnia treatment based on the regulation of the GABAergic system: traditional Chinese medicine perspectives and therapeutic approaches
Cheng, C.-Z., Xie, M.-Z., Tian, Y., Qiao, W.-Q., Yu, Z.-Y., Wang, S., & Yun, F. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1670273 · Cited by 6
Stress ensemble in the BNST mediates comorbid anxiety and sleep disruption
Sun, H., Qiu, Z., Liu, X., Li, Y., Zhao, X., Zhou, Y., Guo, Q., Wu, K., Ma, J., Chen, J., et al. (2026) · Science Advances · doi:10.1126/sciadv.adz9546 · Cited by 5
“Sleep disturbances and generalized anxiety disorder are commonly co-occur, exacerbating each other and resulting in a progressive worsening of symptoms, which consequently makes treatment increasingly challenging ( 1 , 3 , 4 , 6 ).”
Influential
High-Intensity Circuit Training Plus Sleep Health Intervention for Sleep Improvement
Zhang, B., Chen, Z., Liao, Q., Zhang, H., Fang, Y., Wang, W., Song, H., Lau, E. Y. Y., Tse, A. C. Y., Lo, S. K., et al. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.56927 · Cited by 5
Neuropharmacological Activity of the Acetonic Extract of Malpighia mexicana A. Juss. and Its Phytochemical Profile
Avilés-Montes, D., Salinas-Sánchez, D. O., Sotelo-Leyva, C., Zamilpa, A., Batalla-Martinez, F. I., Abarca-Vargas, R., Rivas-González, J. M., Dorado, Ó., Figueroa‐Brito, R., Petricevich, V. L., et al. (2023) · Scientia Pharmaceutica · doi:10.3390/scipharm91040047 · Cited by 5
Insomnia and the Orexinergic Pathway in the Link with Psychopathology: Effects of DORAs in Insomnia Comorbid with Mental Disturbances
Palagini, L., Geoffroy, P. A., Alfì, G., Annuzzi, E., Gurrieri, R., Caruso, V., Miniati, M., Gemignani, A., & Riemann, D. W. (2024) · Current Sleep Medicine Reports · doi:10.1007/s40675-024-00294-9 · Cited by 5
“Insomnia is highly prevalent in anxiety and related disorders and may affect more than 70% of patients with GAD and with PD. Insomnia has been related to the severity of worry, fear, and hypervigilance and to low responsiveness to treatment [2, 11].”
Serum cotinine levels and adolescents’ sleep health outcomes from NHANES 2005 to 2018
Du, X., Peng, T., Ma, L., & Cheng, G. (2024) · Scientific Reports · doi:10.1038/s41598-024-72215-3 · Cited by 5
Therapeutic potential of mackerel-derived peptides and the synthetic tetrapeptide TVGF for sleep disorders in a light-induced anxiety zebrafish model
Wang, Y., Gu, L., Zhang, H., Wang, J., Wang, X., Li, Y., Chai, S., & Xu, C. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1475432 · Cited by 5
Efficacy and safety of lemborexant in subjects with insomnia disorder receiving medications for depression or anxiety symptoms
Krystal, A. D., Blier, P., Culpepper, L., Nierenberg, A. A., Takaesu, Y., Kubota, N., Moline, M. L., Malhotra, M., Pinner, K., & Yardley, J. (2024) · Neuropsychopharmacology Reports · doi:10.1002/npr2.12509 · Cited by 5
Sleep Disturbance in People w ith Anxiety or Depressive Disorders o ver 30 Years, and the Influence o f Personality Disorder
King, J. D., Yang, M., Tyrer, H., & Tyrer, P. J. (2024) · Behavioral Sleep Medicine · doi:10.1080/15402002.2024.2441795 · Cited by 5
“Sleep disturbance is a common feature of both anxiety and depressive disorders (Chellappa & Aeschbach, 2022; Pandi-Perumal et al., 2020).”
Associations between meeting 24h movement behavior guidelines and cognition, gray matter volume, and academic performance in children and adolescents: a systematic review
Liu, B., Shi, P., Jin, T., & Feng, X. (2025) · Archives of Public Health · doi:10.1186/s13690-024-01493-0 · Cited by 5
“Secondly, in terms of mental health, sleep deprivation can increase the risk of depression and anxiety [74, 75], which can interfere with attention and learning efficiency.”
Inverted day-night feeding during pregnancy affects the brain health of both maternal and fetal brains through increasing inflammation levels associated with dysbiosis of the gut microbiome in rats
Wang, X., Kong, X., Ding, Y., An, M., Zhu, X., Guan, Y., & Niu, Y. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03447-x · Cited by 5
“Sleep deprivation has been shown to induce anxiety in both humans and rodents [69, 70], possibly mediated by neurotransmitter and neuro-modulatory systems [71].”
Hypothetical Interventions on Frailty Heterogeneous Trajectories of Older Patients with Gastric Cancer Using Parametric G-Formula
Guo, Y., Miao, X., Chen, Y., Ding, L., Zhao, K., Xu, T., Chen, L., Xu, X., & Xu, Q. (2025) · Annals of Surgical Oncology · doi:10.1245/s10434-025-18026-w · Cited by 5
“36,37 Therefore, after anxiety is alleviated, patients are more likely to resume a normal diet, improve sleep quality, and enhance physical activity, thereby effectively slowing the evolution of the frailty trajectory.”
Sleep loss causes emotional dysregulations increasing depression and anxiety: a reciprocal relationship
Bastos, L. M. V., Viana, L. M. C., Peixoto, M. C. B. G., Pimentel, I. D. S., de Figueirêdo, L. R. B., Jereissati, L. D. O., Lima, L. M. F. V., Aguiar, A. B., & dos Santos, J. C. C. (2023) · Brazilian Journal of Health Review · doi:10.34119/bjhrv6n4-185 · Cited by 6
“Epidemiological studies reveal that about 50% of individuals with anxiety have sleep disorders, especially insomnia, and that insufficient sleep can further stimulate or exacerbate this condition (24).”
BackgroundInfluential
Anxious-Withdrawal and Sleep Problems during Adolescence: The Moderating Role of Peer Difficulties
Bowker, J. C., Gurbacki, J. N., Richard, C. L., & Rubin, K. H. (2023) · Behavioral Sciences · doi:10.3390/bs13090740 · Cited by 4
“In such research, measures of anxiety and negative cognitions should also be included to evaluate the proposed mechanisms of influence in this study [50,51].”
Background
Depression, anxiety, lower sleep quality and social support in square cabin hospitals during Shanghai’s COVID-19 lockdown, China
Quan, L., Xu, S., Xu, H., Chen, F., Wu, S., Zhu, J., Liu, S., & Su, T. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1339774 · Cited by 5
“Some studies also proved that depression (40) and anxiety (41) symptoms could be ameliorated by improving sleep problems.”
Background
Sleep Health and Anxiety Symptoms in Midlife Women: The Study of Women’s Health Across the Nation (SWAN)
Kravitz, H. M., Ruppert, K. M., Lian, P., Neal-Perry, G. S., & Swanson, L. M. (2024) · International Journal of Women s Health · doi:10.2147/ijwh.s455834 · Cited by 7
Effect of weighted blankets on sleep quality among adults with insomnia: a pilot randomized controlled trial
Yu, J., Du, J., Yang, Z., Chen, W., Sun, S., Gan, M., Cai, Y., Zhang, L., Sun, K., Xu, Q., et al. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-06218-9 · Cited by 5
“Given that negative emotions can be instigated and further exacerbated by sleep disturbances [45], the increased sleep quality provided by weighted blanket intervention might be an explanation for the beneficial effects on anxiety and stress.”
Background
La ansiedad y su relación con el síndrome burnout en docentes universitarios
Pro, A. O., & Gómez, D. G. (2022) · Ciencia Latina Revista Científica Multidisciplinar · doi:10.37811/cl_rcm.v6i3.2384 · Cited by 5
Nutritional interventions for the prevention and treatment of neurological disorders such as anxiety, bipolar disorder, depression, epilepsy, multiple sclerosis, and schizophrenia
Madireddy, S., & Madireddy, S. (2022) · Journal of Neuroscience and Neurological Disorders · doi:10.29328/journal.jnnd.1001070 · Cited by 5
“Anxiety disorders are the most common mental illness [41-44]; they affect about one in ive people globally and are among the most frequently diagnosed psychiatric disorders in youth [45,46].”
Background
The Influence of Emotional Regulation and Cognitive Flexibility on Sleep Habits in Spanish Children and Adolescents through the Lens of Parents
Costa-López, B., Lavigne-Cerván, R., Collado-Valero, J. A., de Mier, R. J.-R., & Sória, I. N. (2023) · Children · doi:10.3390/children10081390 · Cited by 4
“Some of them have focused their attention on investigating the bidirectional correlation between sleep habits and emotional regulation [46,47], whereas others have observed the influence of emotional regulation on health habits such as sleep [48,49].”
Background
Association of benzodiazepine and Z‐hypnotic use with cardiovascular disease risk: insights from a prospective study of 10 million people in China
Yang, R., Yu, H., Wu, J., Wang, S., Chen, H., Wang, M., Qin, X., Wu, T., Wu, Y., & Hu, Y. (2024) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13735 · Cited by 4
Bidirectional Relationship Between Atopic Dermatitis and Psychiatric Comorbidities in Individuals of European Ancestry: A Mendelian Randomization Study
Wu, Z., Wu, C., Chen, X., Qian, Q., & Yao, Z. (2025) · Acta Dermato Venereologica · doi:10.2340/actadv.v105.43133 · Cited by 4
“V e n e r e o l o g i ca Z. Wu et al. “Causal relationships between atopic dermatitis and psychiatric comorbidities” 6/7 Acta Derm Venereol 2025 bances, particularly insomnia, affect approximately 50% of individuals with anxiety and can exacerbate the condition (32).”
The relationship between trait anxiety and sleep quality in college students: an exploratory analysis of physical activity as a moderator
Zhong, L., Ma, X., Li, S., & Ling, Y. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1563237 · Cited by 5
“Prior research suggests that trait anxiety may impair sleep quality via heightened stress responses and disrupted neuroregulatory mechanisms, such as HPA axis dysregulation and neurotransmitter imbalance (e.g., glutamate and GABA) (19, 20).”
Anxiety and depression symptoms mediate the impact of neuroticism on insomnia in adults with epilepsy: a cross-sectional study
Hu, P., Li, K., Han, Y., Wang, X., & Xiao, Z. (2025) · BMC Neurology · doi:10.1186/s12883-025-04313-2 · Cited by 4
“…shown that individuals with high levels of neuroticism are more sensitive to stressful life events, tend to amplify stress and hyperfocus in the external environment, and have poor emotion regulation, leading to significant anxiety and depression, and an increased risk of insomnia [49, 55, 56].”
The impact of physical activity on sleep architecture and cognitive function among college students
Ji, Y., Wang, B., Sun, X., Wang, Z., & Chen, W. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1656278 · Cited by 4
“This slow-wave sleep promotes bodily and neural recovery, facilitates the clearance of metabolic waste, and supports memory consolidation (14).”
Effects of exercise interventions on mental health in people with insomnia symptoms: A systematic review and meta-analysis
Wu, Q., Zhou, X., & Xu, L. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106883 · Cited by 4
A latent class analysis of co-occurring insomnia and anxiety among Chinese pregnant women
Liu, S., Huang, M., Tao, J., Wen, D., Ping, Z., Zhang, F. Y., & Li, M. (2024) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2024.2437391 · Cited by 4
“To die, to sleep”: A systematic review and meta-analysis of the relationship between death anxiety and sleep
Menzies, R. E., Brown, J., & Marchant, J. (2025) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2025.103001 · Cited by 4
Unraveling the Molecular Underpinnings: The Therapeutic Impact of Aerobic Exercise on Anxiety Disorders
Rao, Y.-Q., Zhou, Z., Yang, Z.-Q., Liu, M.-X., Gan, X.-Y., Hu, X., Wang, H.-Y., Li, H., & Li, M. (2025) · Current Medical Science · doi:10.1007/s11596-025-00048-w · Cited by 5
“There are various subtypes of anxiety disorders, including general anxiety disorder, panic disorder, social anxiety disorder, and agoraphobia [2].”
Obstructive Sleep Apnea in Pregnancy and its Impact on Maternal-Fetal Health: A Hidden Threat - Narrative Review
Dhamelia, P., Gupta, V., Agarwal, S., Singh, B., & Jain, R. (2025) · The Open Respiratory Medicine Journal · doi:10.2174/0118743064411633250826105304 · Cited by 5
Effects of sleep duration, perceived organisational support and personal resilience on anxiety in non-hospitalised residents during the COVID-19 pandemic: a survey study in Ningbo, China
Zhang, Y., Ma, J., Xu, Q., Rong, Y., Lu, S., & Wang, Z. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-073648 · Cited by 4
Association between sleep traits and sarcopenia‐related traits: A two‐sample bidirectional Mendelian randomization study
Ye, R., Pan, J., Hu, X., Xie, J., & Li, P. (2024) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.14877 · Cited by 5
Identification of potential drug targets for insomnia by Mendelian randomization analysis based on plasma proteomics
Yang, N., Shi, L., Xu, P., Ren, F., Lv, S., Li, C., & Qi, X. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1380321 · Cited by 4
“Insomnia impacts the patient’s quality of life and exhibits a causal relationship with physical and mental illnesses, including cardiovascular disease (6), anxiety (7), depression (8), and even cancer (9).”
Background
The mediating effect of after-midnight use of digital media devices on the association of internet-related addictive behavior and insomnia in adolescents
Lederer-Hutsteiner, T., Müller, K. W., Penker, M., Stolz, E., Greimel, E., & Freidl, W. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1422157 · Cited by 7
“For example anxiety problems may both prolong but also result from sleep problems and therefore act in a bidirectional relationship as a cause, but also as a consequence of insuﬃcient sleep (29, 30).”
Background
Interdisciplinary Fascia Therapy: A Proof-of-Concept Pilot Study for a New Myofascial Approach for Chronic Low Back Pain
Gordon, C. M., Dugan, V., Hörmann, C., & Montoya, P. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13237226 · Cited by 4
“Anxiety and sleep have a bidirectional relationship, i.e., as one increases or decreases so may the other [58].”
Inter-relationships of depression and anxiety symptoms among widowed and non-widowed older adults: findings from the Chinese Longitudinal Healthy Longevity Survey based on network analysis and propensity score matching
Li, Y., Lin, D., Gong, X., Fu, D., Zhao, L., Chen, W., Chen, J., Liu, S., Yang, G., & Cai, Z. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1495284 · Cited by 4
“Previous research established the interrelationship between sleep, anxiety, and depression (95–98).”
Circadian and Sleep Modulation of Dreaming in Women with Major Depression
Birchler-Pedross, A., Frey, S., Cajochen, C., & Chellappa, S. L. (2022) · Clocks & Sleep · doi:10.3390/clockssleep4010012 · Cited by 4
“Likewise, anxiety is frequently comorbid to disrupted sleep and to MDD [42] and often affects dream recall and its emotional salience [37,43].”
BackgroundSelf-citation
Meta-analysis of the efficacy and safety of Huanglian Wendan Decoction alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance
Lei, Y., Liyun, H. E., Xiao, C., Kaiyue, W. A. N. G., Yongjun, F. A. N. G., Zhuang, L. I. A. N. G., & Zhao, Y. (2022) · Digital Chinese Medicine · doi:10.1016/j.dcmed.2022.10.010 · Cited by 4
A Transdiagnostic group therapy for sleep and anxiety among adults with substance use disorders: Protocol and pilot investigation
Milanak, M. E., Witcraft, S. M., Park, J. Y., Hassell, K., McMahon, T. P., & Wilkerson, A. K. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1160001 · Cited by 4
“This session follows the structure and content of a typical CBT-I introductory session.”
BackgroundInfluential
Sleep disturbance and anxiety symptoms among asymptomatic COVID-19 carriers in Shanghai, China: the mediating role of entrapment and defeat
Liu, Y., Ge, X., Zhang, J., Xu, L., Hu, F., Wang, S., Liu, J., Yang, X., Shi, D., & Cai, Y. (2023) · BMC Public Health · doi:10.1186/s12889-023-15803-8 · Cited by 5
“Sleep disturbance could increase the risk of anxiety through a shared and mutually reinforcing neurocircuitry involving dopamine, serotonin, and adenosine [41].”
Background

Authors: Chellappa, S. L., & Aeschbach, D.
Affiliations: University of Cologne (DE)
University of Bonn (DE)
Corresponding author: Chellappa, Sarah L.
ORCID: Chellappa, Sarah L.
Aeschbach, Daniel
Venue: Sleep Medicine Reviews
Publisher: Elsevier BV
Published: 2022-02
Volume: 61
Pages: 101583
ISSN: 1087-0792 (ISSN-L)
DOI: 10.1016/j.smrv.2021.101583
OpenAlex: W4200462974
Cited by: 509
References: 158
Citations by year: 2026: 111 · 2025: 170 · 2024: 135 · 2023: 71 · 2022: 21
FWCI: 9.43
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Sleep Medicine Reviews (publishedVersion)
PubMed (publishedVersion)
Kölner Universitäts PublikationsServer (Universität zu Köln) (publishedVersion)
elib (German Aerospace Center) (acceptedVersion)
ePrints Soton (University of Southampton) (submittedVersion)
Funders: Alexander von Humboldt Foundation
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: sleep, anxiety, insomnia, sleep deprivation, brain networks, arousal, cognitive behavioral therapy for insomnia, non-benzodiazepine hypnotics, antidepressants, lifestyle intervention, non-invasive brain stimulation, slow-wave sleep, sleep interventions
MeSH terms: Anxiety, Anxiety Disorders, Humans, Sleep Initiation and Maintenance Disorders, Sleep, Cognitive Behavioral Therapy

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sleep and anxiety: From mechanisms to interventions

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks