Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells

Idelson, Maria, Alper, Ruslana, Obolensky, Alexey, Ben-Shushan, Etti, Hemo, Itzhak, Yachimovich-Cohen, Nurit, Khaner, Hanita, Smith, Yoav +9 more·2009·Cell stem cell

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Items 301–400 of 484

  1. Bioprocesses for Cell Therapies
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  3. Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells
    Anna Brýmová, Francisco Javier Rodríguez-Jiménez, Annika Konrad, Yaroslav Nemesh, Muhammed Arshad Thottappali, Ana Artero‐Castro, Ruslan Nyshchuk, A. F. Kolesnikova, Brigitte Müller, Hana Studenovská et al. · 2025 · Advanced Science
  4. The promise of stem cells for age-related macular degeneration and other retinal degenerative diseases
    Marco A. Zarbin · 2012 · Drug Discovery Today Therapeutic Strategies
  5. The identification of small molecules that stimulate retinal pigment epithelial cells: potential novel therapeutic options for treating retinopathies
    Ana Artero‐Castro, Štěpán Popelka, Pavla Jendelová, Jan Motlík, Taras Ardan, Francisco Javier Rodriguez Jimenez, Slaven Erceg · 2019 · Expert Opinion on Drug Discovery
  6. Stem Cell Transplantation Therapy for Retinal Degenerative Diseases
    Fabin Han, Guo‐Tong Xu · 2020 · Advances in experimental medicine and biology
  7. Unstimulated, Serum-free Cultures of Retinal Pigment Epithelium Excrete Large Mounds of Drusen-like Deposits
    Xiaoyu Chen, Deepti Singh, Ron Afshari Adelman, Lawrence J. Rizzolo · 2020 · Current Eye Research
  8. Activin A improves retinal pigment epithelial cell survival on stiff but not soft substrates
    Corina White, Bryan Kwok, Ronke M. Olabisi · 2018 · Journal of Biomedical Materials Research Part A
  9. Effects of ECM protein-coated surfaces on the generation of retinal pigment epithelium cells differentiated from human pluripotent stem cells
    Zeyu Tian, Qian Liu, Hui-Yu Lin, Yu-Ru Zhu, Ling Ling, Tzu‐Cheng Sung, Ting Wang, Wanqi Li, Min Gao, Sitian Cheng et al. · 2024 · Regenerative Biomaterials
  10. RPE Polarity and Barrier Function
    Lawrence J. Rizzolo · 2020 · Springer eBooks
  11. TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status
    Inês Ramos Rego, Daniela Silvério, Maria Isabel Eufrásio, Sandra S. Pinhanços, Bruna Lopes da Costa, José Teixeira, Hugo Fernandes, Yang Kong, Yao Li, Stephen H. Tsang et al. · 2023 · Antioxidants
  12. Regeneration of the Retina Using Pluripotent Stem Cells: A Comprehensive Review
    Yash V Lath, Archana Ramkrishna Thool, Indrayani Jadhav · 2024 · Cureus
  13. Towards Stem/Progenitor Cell-Based Therapies for Retinal Degeneration
    Hui Liu, Shuaiyan Lu, Ming Chen, Na Gao, Yuhe Yang, Huijuan Hu, Qing Ren, Xiaoyu Liu, Hong‐Xu Chen, Qunyan Zhu et al. · 2024 · Stem Cell Reviews and Reports
  14. Pluripotent stem cells: A therapeutic source for age-related macular degeneration
    Subramanian Krishnakumar, Sowmya Parameswaran · 2017 · Indian Journal of Ophthalmology
  15. Screening and optimization of potential injection vehicles for storage of retinal pigment epithelial stem cell before transplantation
    Yangzi Isabel Tian, Richard Davis, Michael R. Zonca, Jeffrey H. Stern, Sally Temple, Yubing Xie · 2018 · Journal of Tissue Engineering and Regenerative Medicine
  16. Human Embryonic Stem Cells in Regenerative Medicine
    Odessa Yabut, Harold S. Bernstein · 2011 · Humana Press eBooks
  17. Embryonic Stem Cells as a Cell Source for Tissue Engineering
    Ali Khademhosseini, Jeffrey M. Karp, Sharon Gerecht, Lino Ferreira, Nasim Annabi, Dario Sirabella, Gordana Vunjak‐Novakovic, Róbert Langer · 2013 · Elsevier eBooks
  18. Nicotinamide: a novel treatment for age-related macular degeneration?
    Peter D. Westenskow · 2017 · Stem Cell Investigation
  19. AMD and Stem Cell-Based Therapies
    Joseph C. Giacalone, David H. Parkinson, Daniel A. Balikov, Rajesh C. Rao · 2023 · International Ophthalmology Clinics
  20. Challenges of cell therapies for retinal diseases
    Christelle Monville, Lise Morizur, Karim Ben M’Barek · 2022 · International review of neurobiology
  21. Transplantation Frontiers
    Vamsi K. Gullapalli, Mohamad A. Khodair, Hao Wang, Ilene K. Sugino, Steven A. Madreperla, Marco A. Zarbin · 2012 · Elsevier eBooks
  22. Steady Advance of Stem Cell Therapies: Report from the 2011 World Stem Cell Summit, Pasadena, California, October 3–5
    Melanie Swan · 2011 · Rejuvenation Research
  23. Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases
    Maria Dodina, Dzerassa Gurtsieva, Alexander V. Karabelsky, Ekaterina Minskaia · 2024 · Frontiers in Cell and Developmental Biology
  24. Integration of human stem cell-derived in vitro systems and mouse preclinical models identifies complex pathophysiologic mechanisms in retinal dystrophy
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  25. Evaluating role of bone marrow-derived stem cells in dry age-related macular degeneration using multifocal electroretinogram and fundus autofluorescence imaging
    Atul Kumar, Neha Midha, Sujata Mohanty, Annu Chohan, Tulika Seth, Varun Gogia, Shikha Gupta · 2017 · International Journal of Ophthalmology
  26. Stem Cells and Ocular Tissue Regeneration
    Yizhi Liu, Jing Wang, Yan Luo, Shuyi Chen, Michelle E. Lewallen, Ting Xie · 2013 · Asia-Pacific Journal of Ophthalmology
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    Jing-Xue Zhang, Ningli Wang, Qingjun Lu · 2015 · PubMed Central
  28. WITHDRAWN: Bioengineering approaches for modelling retinal pathologies of the outer blood-retinal barrier
    Blanca Molins, Marina Mesquida, Alfredo Adán · 2022 · Progress in Retinal and Eye Research · Retracted
  29. The Synthetic Extracellular Matrix as a Maestro of the In Vitro Stem Cell Niche: Orchestrating Fate and Function
    Subhajit Giri, Pratyush Rajesh · 2026 · Biomedicines
  30. Chordin-like 2 influences the differentiation fate of retinal pigment epithelium cells by dynamically regulating BMP pathway
    Duo Li, Xinyi Xie, Han Shen, Qinghuai Liu, Yong Yao · 2022 · International Journal of Ophthalmology
  31. Epithelial-Mesenchymal Transition: Molecular Mechanisms of Retinal Pigment Epithelial Cell Activation
    A. Kuznetsova · 2022 · Russian Journal of Developmental Biology
  32. The potential of stem cell-based therapy for retinal repair
    Kin‐Sang Cho, Honghua Yu, Lin Zhang Cheng · 2014 · Neural Regeneration Research
  33. Microenvironment-evoked cell lineage conversion: Shifting the focus from internal reprogramming to external forcing
    Ji Lin, Meirong Li, Dongdong Ti, Meixia Chen, Hao-jie Hao, Yali Zhao, Xiaobing Fu, Weidong Han · 2012 · Ageing Research Reviews
  34. Low level of activin A secreted by fibroblast feeder cells accelerates early stage differentiation of retinal pigment epithelial cells from human pluripotent stem cells
    Heidi Hongisto, Alexandra Mikhailova, Hanna Hiidenmaa, Tanja Ilmarinen, Heli Skottman · 2012 · Stem Cell Discovery
  35. Accelerated Three-Dimensional Neuroepithelium Formation from Human Embryonic Stem Cells and Its Use for Quantitative Differentiation to Human Retinal Pigment Epithelium
    Yu Zhu, Sven Schreiter, Elly Margaret Tanaka · 2013 · Methods in molecular biology
  36. Generation of Induced-Primary Retinal Pigment Epithelium from Human Retinal Organoids
    Miguel Flores‐Bellver, M. Valeria Canto-Soler · 2024 · Methods in molecular biology
  37. The eyeball’s connected to the brain ball
    Rajesh C. Rao, Jeffrey H. Stern, Sally Temple · 2021 · Cell stem cell
  38. Nuclear reprogramming to treat retinal degenerative diseases
    Fumitaka Osakada · 2011 · Inflammation and Regeneration
  39. The Germline/Soma Dichotomy: Implications for Aging and Degenerative Disease
    Michael D. West, François Binette, David LaRocca, Karen B. Chapman, Charles S. Irving, Hal Sternberg · 2016 · Regenerative Medicine
  40. Characterization of a spontaneously generated murine retinal pigmented epithelium cell line; a model for in vitro experiments
    Ehsan Ranaei Pirmardan, Zahra‐Soheila Soheili, Shahram Samiei, Hamid Ahmadieh, Seyed Javad Mowla, Razie Ezzati, Marzieh Naseri · 2016 · Experimental Cell Research
  41. Chapter 4 - Restoring Vision to the Blind: Stem Cells and Transplantation
    The Lasker IRRF Initiative for Innovation in Vision Science The Lasker IRRF Initiative for Innovation in Vision Science · 2014 · Translational Vision Science & Technology
  42. Tissue Engineering for Stem Cell Mediated Regenerative Medicine
    Janet Zoldan, Thomas P. Kraehenbuehl, Abigail K. R. Lytton‐Jean, Róbert Langer, Daniel G. Anderson · 2010
  43. Subretinal suspensions of hiPSC-derived retinal pigment epithelium cells form functional monolayers in NOD-SCID mice facilitating treatment of advanced retinal diseases
    Xiaojing Song, Guanjie Gao, Ke Ye, Ping Xu, Yuan Wang, Suai Zhang, Dandan Zheng, Jian Ge, Xiufeng Zhong · 2025 · Regenerative Therapy
  44. Development of a Manufacturing Process for Clinical Autologous hiPSC-Derived Retinal Pigment Epithelium
    Shekhar Jha, Fang Hua, Roba Dejene, Sarmila Sarkar, Ruchi Sharma, Kapil Bharti · 2025 · Advances in experimental medicine and biology
  45. Eyeing the Fountain of Youth
    Magali Saint‐Geniez, Mariana Aparecida Brunini Rosales · 2017 · Cell stem cell
  46. Low-oxygen and knock-out serum maintain stemness in human retinal progenitor cells
    Deepti Singh, Pierre C. Dromel, Michael J. Young · 2020 · Molecular Biology Reports
  47. Retinal Tissue Engineering: Regenerative and Drug Delivery Approaches
    Azadeh Izadyari Aghmiuni, Saeed Heidari Keshel, Ali Rahmani, Samad Nadri, Farshid Sefat, Alireza Lashay · 2022 · Current Stem Cell Research & Therapy
  48. Survival of Neural Progenitors Derived from Human Embryonic Stem Cells Following Subretinal Transplantation in Rodents
    Hamzah Aweidah, Chen Matsevich, Hanita Khaner, Masha Idelson, Ayala Ejzenberg, Benjamin E. Reubinoff, Eyal Banin, Alexey Obolensky · 2023 · Journal of Ocular Pharmacology and Therapeutics
  49. Stem cell therapy in retinal diseases: current evidence
    Leopoldo Rubinato, Enrico Redolfi De Zan, Valentina Sarao, Daniele Veritti, Paolo Lanzetta · 2023 · Expert Review of Ophthalmology
  50. Retinal therapy with induced pluripotent stem cells; leading the way to human clinical trials
    Anat Yanai, Pia McNab, Kevin Gregory-Evans · 2019 · Expert Review of Ophthalmology
  51. Human Pluripotent Stem Cells as In Vitro Models for Retinal Development and Disease
    Akshayalakshmi Sridhar, Kirstin B. Langer, Clarisse M. Fligor, Matthew R. Steinhart, Casey A. Miller, Kimberly T. Ho-A-Lim, Sarah K. Ohlemacher, Jason S. Meyer · 2018 · Fundamental biomedical technologies
  52. Emerging options for the management of age-related macular degeneration with stem cells
    Mooney, James LaMotte · 2010 · Stem Cells and Cloning Advances and Applications
  53. Guiding Differentiation of Stem Cells in Vivo by Tetracycline-Controlled Expression of Key Transcription Factors
    E. Kozlova, C. Berens · 2012 · Cell Transplantation
  54. Strategies of Regenerative Medicine
    David L. Stocum · 2012 · Elsevier eBooks
  55. Biomanufacturing Human Pluripotent Stem Cells for Therapeutic Applications
    Xiaojun Lance Lian, Sean P. Palecek · 2012 · Humana Press eBooks
  56. Derivation of Retinal Pigmented Epithelial Cells for the Treatment of Ocular Disease
    Dennis Clegg, Sherry T. Hikita, Qirui Hu, D. E. Buchholz, Teisha J. Rowland, Britney O. Pennington, Roxanne H. Croze, Lyndsay L. Leach, Marlene S. Tsie, Lisa R. Conti et al. · 2013 · Springer eBooks
  57. Generation of eye field/optic vesicle-like structures from human embryonic stem cells under two-dimensional and chemically defined conditions
    Maryam Parvini, Kazem Parivar, Fatemeh Safari, Mahdi Tondar · 2014 · In Vitro Cellular & Developmental Biology - Animal
  58. Generation of a BEST1 Pr-EGFP reporter human embryonic stem cell line via CRISPR/Cas9 editing
    Shuaiyan Lu, Ming Chen, Xiaoyu Liu, Jiahang Li, Hui Liu, Shasha Li · 2024 · Stem Cell Research
  59. Differentiation of Human Embryonic Stem Cells and Human Induced Pluripotent Stem Cells into Retinal Pigment Epithelium
    Heli Skottman · 2012 · Stem cells and cancer stem cells
  60. hPSC-derived RPE transplantation for the treatment of macular degeneration
    Qian Liu, Jun Liu, Akon Higuchi · 2023 · Progress in molecular biology and translational science
  61. Embryonic Stem Cell Therapy – From Bench to Bed
    E. Laura · 2013 · InTech eBooks
  62. In Vitro Histogenesis of Human Embryonic Stem Cells into Retina Components
    Maria A. Lagarkova, Alexander G. Shilov, Н. В. Губанова, M.A. Prokhorovich, С. Л. Киселев · 2012 · Bulletin of Experimental Biology and Medicine
  63. Embryonic stem cells and retinal regeneration
    Gorzata Woronkowicz, Piotr Skopiński · 2010
  64. Induced Pluripotent Stem Cell-Derived Autologous Cell Therapy for Age-Related Macular Degeneration
    V. Khristov, B. S. Jha, Aaron Rising, Yi-Chao Li, H. Qian, A. Maminishkis, J. Amaral, M. Campos, K. Bharti · 2017 · Springer eBooks
  65. “Disease in a Dish” Modeling of Retinal Diseases
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  66. Stem Cells and Cellular Therapy
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  68. Stem Cell and Gene Therapy for Inherited Retinal Diseases
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  69. The Potential of Stem Cells in Ocular Treatments
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  70. Comprehensive Analysis of Photoreceptor Outer Segments: Flow Cytometry Characterization and Stress-Driven Impact on Retinal Pigment Epithelium Phagocytosis
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  72. Understanding Retinal Development Can Inform Future Regenerative Therapies
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  73. Progress in human embryonic stem cell research and aging
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  81. Differentiation of Human Pluripotent Stem Cells into Retinal Cells
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  88. Photoreceptor transplantation into the mammalian retina
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  89. Age-related macular degeneration treatment in the era of molecular medicine
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  90. Activin A promotes human embryonic stem cells to directly differentiate into retinal pigment epithelium cells
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  91. Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cell Transplantation for Retinal Degeneration
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  92. Pluripotent stem cells and mitochondrial dysfunction
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  96. Cell Therapy for Neurodegenerative Disorders
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  99. Stem Cells and the Retina – Challenges for Regenerative Medicine
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