Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells

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Items 201–300 of 484

1. Application of stem cell-derived retinal pigmented epithelium in retinal degenerative diseases: present and future
   Mingyue Luo, Youxin Chen · 2018 · International Journal of Ophthalmology
2. Expression profiling of cell-intrinsic regulators in the process of differentiation of human iPSCs into retinal lineages
   Jen-Hua Chuang, Aliaksandr A. Yarmishyn, De‐Kuang Hwang, Chih‐Chien Hsu, Mong‐Lien Wang, Yi-Ping Yang, Ke‐Hung Chien, Shih‐Hwa Chiou, Chi‐Hsien Peng, Shih‐Jen Chen · 2018 · Stem Cell Research & Therapy
3. Subretinal transplantation of putative retinal pigment epithelial cells derived from human embryonic stem cells in rat retinal degeneration model
   Un Chul Park, Myung Soo Cho, Jung‐Hyun Park, Sang Jin Kim, Seung‐Yup Ku, Young Min Choi, Shin Yong Moon, Hyeong Gon Yu · 2011 · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine
4. A gene expression profile of the developing human retinal pigment epithelium.
   Zhongyu Zhang, Yan Zhang, Huizhen Xiao, Xiaolei Liang, Dawei Sun, Shaomin Peng · 2012 · Europe PMC (PubMed Central)
5. Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development
   Yamit Cohen‐Tayar, Hadar Cohen, Yulia Mitiagin, Zohar Abravanel, Carmit Levy, Masha Idelson, Benjamin E. Reubinoff, Shalev Itzkovitz, Shaul Raviv, Klaus H. Kaestner et al. · 2018 · Development
6. Differentiation of Pluripotent Stem Cells into Retinal Pigmented Epithelium
   Roxanne H. Croze, Dennis Clegg · 2014 · Developments in ophthalmology
7. A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases
   Janosch Peter Heller, Jessica C. F. Kwok, Elena Vecino, Keith R G Martin, James W. Fawcett · 2015 · Frontiers in Cellular Neuroscience
8. Rapid Differentiation of Multi-Zone Ocular Cells from Human Induced Pluripotent Stem Cells and Generation of Corneal Epithelial and Endothelial Cells
   Zongyi Li, Haoyun Duan, Wenjing Li, Xiaoli Hu, Yanni Jia, Can Zhao, Songmei Zhang, Qingjun Zhou, Weiyun Shi · 2019 · Stem Cells and Development
9. Preclinical safety studies of human embryonic stem cell-derived retinal pigment epithelial cells for the treatment of age-related macular degeneration
   Sandra Petrus-Reurer, Pankaj Kumar, Sara Padrell Sánchez, Monica Aronsson, Helder André, Hammurabi Bartuma, Álvaro Plaza Reyes, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner · 2020 · Stem Cells Translational Medicine
10. Efficient Delivery and Functional Expression of Transfected Modified mRNA in Human Embryonic Stem Cell-derived Retinal Pigmented Epithelial Cells
    Magnus L. Hansson, Sílvia Albert, Louisa González Somermeyer, Rubén Peco, Eva Mejía-Ramírez, Núria Montserrat, Juan Carlos Izpisúa Belmonte · 2015 · Journal of Biological Chemistry
11. The 3R principle: advancing clinical application of human pluripotent stem cells
    Michael D. O’Connor · 2013 · Stem Cell Research & Therapy
12. Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation
    Mária Szatmári-Tóth, Tanja Ilmarinen, Alexandra Mikhailova, Heli Skottman, Anu Kauppinen, Kai Kaarniranta, Endre Kristóf, Lyubomyr M. Lytvynchuk, Zoltán Veréb, László Fésüs et al. · 2019 · International Journal of Molecular Sciences
13. Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations
    Qingqing Zhao, Yang Kong, Alec Kittredge, Yao Li, Yin Shen, Yu Zhang, Stephen H. Tsang, Tingting Yang · 2021 · eLife
14. Where Are We with RPE Replacement Therapy? A Translational Review from the Ophthalmologist Perspective
    Raffaele Raimondi, Piero Zollet, Francesco Paolo De Rosa, Panagiotis Tsoutsanis, Matteo Stravalaci, Marianna Paulis, Antonio Inforzato, Mario Rosario Romano · 2022 · International Journal of Molecular Sciences
15. miR-410 Inhibition Induces RPE Differentiation of Amniotic Epithelial Stem Cells via Overexpression of OTX2 and RPE65
    Soon Won Choi, Jae-Jun Kim, Min–Soo Seo, Sang‐Bum Park, Tae‐Wook Kang, Jin Young Lee, Byung‐Chul Lee, Insung Kang, Tae–Hoon Shin, Hyung‐Sik Kim et al. · 2014 · Stem Cell Reviews and Reports
16. Transplantation of Retinal Progenitor Cells from Optic Cup-Like Structures Differentiated from Human Embryonic Stem Cells In Vitro and In Vivo Generation of Retinal Ganglion-Like Cells
    Songtao Wang, Li-li Chen, Peng Zhang, Xiaobing Wang, Yan Sun, Lixiang Ma, Qiong Liu, Guomin Zhou · 2018 · Stem Cells and Development
17. Cell Therapy for Retinal Degenerative Diseases: Progress and Prospects
    Kevin Yang Wu, Jaskarn K. Dhaliwal, Akash Sasitharan, Ananda Kalevar · 2024 · Pharmaceutics
18. Differentiation of Human Embryonic Stem Cells Using Size-Controlled Embryoid Bodies and Negative Cell Selection in the Production of Photoreceptor Precursor Cells
    Anat Yanai, Christopher Laver, Aaron W. Joe, Ishaq Ahmed viringipurampeer, Xia Wang, Cheryl Y. Gregory, Kevin Gregory-Evans · 2013 · Tissue Engineering Part C Methods
19. CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions
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20. Integrated Analysis of DNA Methylation and RNA Transcriptome during In Vitro Differentiation of Human Pluripotent Stem Cells into Retinal Pigment Epithelial Cells
    Zhenshan Liu, Rongfeng Jiang, Songtao Yuan, Na Wang, Yun Feng, Ganlu Hu, Xianmin Zhu, Kevin Y. Huang, Jieliang Ma, Guo‐Tong Xu et al. · 2014 · PLoS ONE
21. Derivation, characterization and retinal differentiation of induced pluripotent stem cells
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22. Retinal Stem Cells and Regeneration of Vision System
    Henry Ka-Fun Yip · 2013 · The Anatomical Record
23. Efficient Derivation of Retinal Pigment Epithelium Cells from Stem Cells
    Peter D. Westenskow, Zack A. Sedillo, Ashley Barnett, Martin Friedlander · 2015 · Journal of Visualized Experiments
24. EXPRESSION OF SIRT1 IN CHOROIDAL NEOVASCULAR MEMBRANES
    S. Maloney, E. Antecka, Tamara Granner, Bruno Franco Fernandes, Li‐Anne S. Lim, María Eugenia Orellana, Miguel N. Burnier · 2012 · Retina
25. Inhibition by miR-410 facilitates direct retinal pigment epithelium differentiation of umbilical cord blood-derived mesenchymal stem cells
    Choi, Soon Won, Kim, Jae-Jun, Seo, Min-Soo, Park, Sang-Bum, Shin, Tae-Hoon, Shin, Ji-Hee, Seo, Yoojin, Kim, Hyung-Sik, Kang, Kyung-Sun · 2017 · Journal of Veterinary Science
26. The advancement of human pluripotent stem cell-derived therapies into the clinic
    R. Thies, C. Murry · 2015 · Development
27. Metabolic–Epigenetic Axis in Pluripotent State Transitions
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28. Mesenchymal stem cell surgery, rescue and regeneration in retinitis pigmentosa: clinical and rehabilitative prognostic aspects
    Paolo Giuseppe Limoli, Celeste Limoli, Marco Ulises Morales, Enzo Maria Vingolo · 2020 · Restorative Neurology and Neuroscience
29. The New Era of Therapeutic Strategies for the Treatment of Retinitis Pigmentosa: A Narrative Review of Pathomolecular Mechanisms for the Development of Cell-Based Therapies
    Valentina Becherucci, Giacomo Maria Bacci, Elisa Marziali, Andrea Sodi, Franco Bambi, Roberto Caputo · 2023 · Biomedicines
30. PROGRESS TOWARD THE MAINTENANCE AND REPAIR OF DEGENERATING RETINAL CIRCUITRY
    Anthony Vugler · 2010 · Retina
31. The contribution of human/non-human animal chimeras to stem cell research
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32. MicroRNA-based system in stem cell reprogramming; differentiation/dedifferentiation
    Fatemeh Pourrajab, Mojtaba Babaei Zarch, Mohammad BaghiYazdi, Seyedhossein Hekmatimoghaddam, Mohamad Reza Zare‐Khormizi · 2014 · The International Journal of Biochemistry & Cell Biology
33. New medium used in the differentiation of human pluripotent stem cells to retinal cells is comparable to fetal human eye tissue
    Xiaobing Wang, Kai Xiong, Cong Lin, Lei Lv, Jing Chen, Chongchong Xu, Songtao Wang, Dandan Gu, Hua Zheng, Hurong Yu et al. · 2015 · Biomaterials
34. iPSC‐Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow‐Up Study
    Peter D. Westenskow, Felicitas Bucher, Stephen Bravo, Toshihide Kurihara, Daniel Feitelberg, Liliana P Paris, Edith Aguilar, Jonathan H. Lin, Martin Friedlander · 2016 · Stem Cells International
35. Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium
    Parul Choudhary, Alex Gutteridge, Emma Impey, R. Ian Storer, Robert M. Owen, Paul John Whiting, Magda Bictash, Caroline Benn · 2016 · Stem Cells Translational Medicine
36. Developing Cell-Based Therapies for RPE-Associated Degenerative Eye Diseases
    Karim Ben M’Barek, Walter Habeler, Florian Régent, Christelle Monville · 2019 · Advances in experimental medicine and biology
37. Antioxidant and Biological Properties of Mesenchymal Cells Used for Therapy in Retinitis Pigmentosa
    Paolo Giuseppe Limoli, Enzo Maria Vingolo, Celeste Limoli, Marcella Nebbioso · 2020 · Antioxidants
38. Cell-Based Therapies for Age-Related Macular Degeneration
    Samer Khateb, Shekhar Jha, Kapil Bharti, Eyal Banin · 2021 · Advances in experimental medicine and biology
39. Robust induction of retinal pigment epithelium cells from human induced pluripotent stem cells by inhibiting FGF/MAPK signaling
    Takao Kuroda, Satoshi Ando, Yuriko Takeno, Akiyoshi Kishino, Tōru Kimura · 2019 · Stem Cell Research
40. Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells
    Oriane Rubio, Tracy A. Hookway, Todd C. McDevitt · 2016 · Current Stem Cell Reports
41. Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration
    Peter D. Westenskow, Toshihide Kurihara, Martin Friedlander · 2014 · Advances in experimental medicine and biology
42. Enhanced Functional Integration of Human Photoreceptor Precursors into Human and Rodent Retina in an Ex Vivo Retinal Explant Model System
    Anat Yanai, Christopher Laver, Cheryl Y. Gregory, Ran R. Liu, Kevin Gregory-Evans · 2015 · Tissue Engineering Part A
43. Ethical issues in biomedical use of human embryonic stem cells (hESCs)
    D. Ghosh, N. Mehta, A. Patil, J. Sengupta · 2016 · Journal of Reproductive Health and Medicine
44. Restoring Vision Using Stem Cells and Transplantation
    Elisa Cuevas, Paresh A. Parmar, Jane C. Sowden · 2019 · Advances in experimental medicine and biology
45. Recent Advances towards the Clinical Application of Stem Cells for Retinal Regeneration
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46. Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation
    Junhua Wang, Peter D. Westenskow, Mingliang Fang, Martin Friedlander, Gary E. Siuzdak · 2016 · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
47. Cell and Gene Therapy
    Rajesh C. Rao, David N. Zacks · 2014 · Developments in ophthalmology
48. Retinal Pigment Epithelium Differentiation of Stem Cells: Current Status and Challenges
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49. Regenerative medicine in Huntington's disease: Current status on fetal grafts and prospects for the use of pluripotent stem cell
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50. Impedance Spectroscopy in Monitoring the Maturation of Stem Cell-Derived Retinal Pigment Epithelium
    Virpi Savolainen, Kati Juuti‐Uusitalo, Niina Onnela, Hanna Vaajasaari, Susanna Narkilahti, Riitta Suuronen, Heli Skottman, Jari Hyttinen · 2011 · Annals of Biomedical Engineering
51. Animal models for the evaluation of retinal stem cell therapies
    Biju B. Thomas, Deepthi S. Rajendran Nair, Mana Rahimian, Amr K. Hassan, Thuy-Linh Tran, Magdalene J. Seiler · 2025 · Progress in Retinal and Eye Research
52. Culturing human pluripotent stem cells for regenerative medicine
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53. Beneath the sword of Damocles: regenerative medicine and the shadow of immunogenicity.
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54. In vitro Differentiation of Human iPSC-derived Retinal Pigment Epithelium Cells (iPSC-RPE)
    Agnieszka D’Antonio‐Chronowska, Matteo D’Antonio, Kelly A. Frazer · 2019 · BIO-PROTOCOL
55. Yap1 is required for maintenance of adult RPE differentiation
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56. Lab generated retina: Realizing the dream
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57. Strategies for retinal cell generation from human pluripotent stem cells
    Lindsey Weed, Jason A. Mills · 2017 · Stem Cell Investigation
58. Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings
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59. Biotechnology and Biomaterial-Based Therapeutic Strategies for Age-Related Macular Degeneration. Part II: Cell and Tissue Engineering Therapies
    Nahla Jemni-Damer, Atocha Guedan-Duran, María Fuentes-Andion, Nora Serrano-Bengoechea, Nuria Alfageme-Lopez, Félix Armadá-Maresca, Gustavo V. Guinea, José Pérez‐Rigueiro, Francisco Javier Rojo, Daniel González‐Nieto et al. · 2020 · Frontiers in Bioengineering and Biotechnology
60. Scaffold free retinal pigment epithelium sheet engineering using modified alginate-RGD hydrogel
    Sareh Soroushzadeh, Fereshteh Karamali, Elahe Masaeli, Atefeh Atefi, Mohammad Hossein Nasr‐Esfahani · 2022 · Journal of Bioscience and Bioengineering
61. Clinical trials in retinal dystrophies
    Dean Eliott, SeannaR Grob, Avni P. Finn, ThanosD Papakostas · 2016 · Middle East African Journal of Ophthalmology
62. Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs
    Peng Li, Xiaofeng Sun, Zhizhong Ma, Yinan Liu, Ying Jin, Ruimin Ge, Limin Hao, Yanling Ma, Shuo Han, Haojie Sun et al. · 2016 · International Journal of Biological Sciences
63. Potential of Gene Editing and Induced Pluripotent Stem Cells (iPSCs) in Treatment of Retinal Diseases.
    Katherine Chuang, Fields Ma, Lucian V Del Priore · 2017 · PubMed Central
64. Advances in retinal stem cell biology.
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65. Efficient Production of Photoreceptor Precursor Cells from Human Embryonic Stem Cells
    Anat Yanai, Christopher Laver, Aaron W. Joe, Kevin Gregory-Evans · 2013 · Methods in molecular biology
66. Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations
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67. Human Amniotic Epithelial Stem Cell-Derived Retinal Pigment Epithelium Cells Repair Retinal Degeneration
    Jinying Li, Chen Qiu, Yang Wei, Weixin Yuan, Jia Liu, Wenyu Cui, Jiayi Zhou, Cong Qiu, Lihe Guo, Liquan Huang et al. · 2021 · Frontiers in Cell and Developmental Biology
68. Human Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium in Retinal Treatment: from Bench to Bedside
    Maryam Parvini, Leila Satarian, Kazem Parivar, Mohammad Javan, Mahdi Tondar, Sajjad Ahmad, Hossein Baharvand · 2014 · Molecular Neurobiology
69. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells
    Parul Choudhary, Benjamin T. Dodsworth, Ben S. Sidders, Alex Gutteridge, Christos Michaelides, Joshua K. Duckworth, Paul John Whiting, Caroline Benn · 2015 · PLoS ONE
70. Differentiation, Maintenance, and Analysis of Human Retinal Pigment Epithelium Cells: A Disease-in-a-dish Model for BEST1 Mutations
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71. The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration
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72. Transient Retention of Photoreceptor Outer Segments in Matrigel-Embedded Retinal Organoids
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73. Hepatocytic parental progenitor cells of rat small hepatocytes maintain self-renewal capability after long-term culture
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74. The ROCK Inhibitor Y-26732 Enhances the Survival and Proliferation of Human Embryonic Stem Cell-Derived Neural Progenitor Cells upon Dissociation
    Ruttachuk Rungsiwiwut, Chirawattana Manolertthewan, Pranee Numchaisrika, Vichuda Ahnonkitpanit, Pramuan Virutamasen, Mongkol Techakumphu, Kamthorn Pruksananonda · 2013 · Cells Tissues Organs
75. Human pluripotent stem cells for the modelling of retinal pigment epithelium homeostasis and disease: A review
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76. Magnetic Iron Oxide Nanoparticle Labeling of Photoreceptor Precursors for Magnetic Resonance Imaging
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77. iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function
    Kevin Eade, Brendan R. E. Ansell, Sarah Giles, Regis J. Fallon, Sarah R. Harkins-Perry, Takayuki Nagasaki, Simone Tzaridis, Martina Wallace, Elizabeth Anne Mills, Samaneh Farashi et al. · 2023 · Journal of Clinical Investigation
78. Possibilities for Using Pluripotent Stem Cells for Restoring Damaged Eye Retinal Pigment Epithelium
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79. Cell Biology of the Retinal Pigment Epithelium
    Gabriele Thumann, Guo‐Rui Dou, Yusheng Wang, David R. Hinton · 2012 · Elsevier eBooks
80. Embryonic stem cells as a cell source for tissue engineering
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81. Stem Cells for Retinal Repair
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82. Nicotinamide Promotes Formation of Retinal Organoids From Human Pluripotent Stem Cells via Enhanced Neural Cell Fate Commitment
    Florian Régent, Zachary A. Batz, Ryan A. Kelley, Linn M. Gieser, Anand Swaroop, Holly Y. Chen, Tiansen Li · 2022 · Frontiers in Cellular Neuroscience
83. Transcription factor overexpression drives reliable differentiation of retinal pigment epithelium from human induced pluripotent stem cells
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84. Derivation, culture and retinal pigment epithelial differentiation of human embryonic stem cells using human fibroblast feeder cells
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85. New concepts for reconstruction of retinal and pigment epithelial tissues
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86. Strategies for enrichment and selection of stem cell-derived tissue precursors
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87. Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level
    Florian Udry, Sarah Decembrini, David M. Gamm, Nicole Déglon, Corinne Kostic, Yvan Arsenijévic · 2020 · Scientific Reports
88. Tissue engineering approaches towards the regeneration of biomimetic scaffolds for age-related macular degeneration
    Shambhavi Bagewadi, Sowmya Parameswaran, Subramanian Krishnakumar, Swaminathan Sethuraman, Anuradha Subramanian · 2021 · Journal of Materials Chemistry B
89. Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy
    Yao Li, Richard R Yang, Yong-Shi Li, Chun-Wei Hsu, Laura A. Jenny, Yang Kong, Merry ZC Ruan, Janet R. Sparrow, Stephen H. Tsang · 2024 · JCI Insight
90. Enriched Cultures of Retinal Cells From BJNhem20 Human Embryonic Stem Cell Line of Indian Origin
    Indumathi Mariappan, Savitri Maddileti, Praveen Joseph Susaimanickam, Jamila H. Siamwala, Vasundhara Vauhini · 2015 · Investigative Ophthalmology & Visual Science
91. Sense and Serendipity Aid RPE Generation
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92. Eyes open to stem cells: safety trial may pave the way for cell therapy to treat retinal disease in patients
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93. Stem Cell Surgery and Growth Factors in Retinitis Pigmentosa Patients: Pilot Study After Literature Review
    Paolo Giuseppe Limoli, Enzo Maria Vingolo, Marco Ulises Morales, Celeste Limoli, Marcella Nebbioso · 2019 · Preprints.org
94. Stem cell-based therapies for retinal diseases: focus on clinical trials and future prospects
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95. Efficient and robust induction of retinal pigment epithelium cells by tankyrase inhibition regardless of the differentiation propensity of human induced pluripotent stem cells
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96. Challenges in Retinal Circuit Regeneration
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97. Regenerative Medicine: Solution in Sight
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98. Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
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99. Stem cell transplantation as a progressing treatment for retinitis pigmentosa
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100. Sorsby fundus dystrophy (SFD): A narrative review
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