p53-Mediated Hematopoietic Stem and Progenitor Cell Competition
Bondar, Tanya, Medzhitov, Ruslan·2010·Cell Stem Cell
Cited by (343)
Items 101–200 of 343
- Resilient and resourceful: Genome maintenance strategies in hematopoietic stem cellsSietske T. Bakker, Emmanuelle A. Passegue · 2013 · Experimental Hematology
- Two-signal requirement for growth-promoting function of Yap in hepatocytesSu, Tian, Bondar, Tanya, Zhou, Xu, Zhang, Cuiling, He, Hang, Medzhitov, Ruslan · 2015 · eLife
- Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulationJinzhi Lei, Simon A. Levin, Qing Hua Nie · 2014 · Proceedings of the National Academy of Sciences
- Hematopoietic stem and progenitor cell signaling in the nicheStephanie N. Hurwitz, Seul K Jung, Peter Kurre · 2020 · Leukemia
- Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damageGutierrez-Martinez, Paula, Hogdal, Leah, Nagai, Manavi, Kruta, Miriama, Singh, Rumani, Sarosiek, Kristopher, Nussenzweig, Andre, Beerman, Isabel, Letai, Anthony, Rossi, Derrick J. · 2018 · Nature Cell Biology
- Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphomaChang‐Lung Lee, Katherine D. Castle, Everett James Moding, Jordan M. Blum, Nerissa T. Williams, Lixia Luo, Yan Ma, Luke B. Borst, Yongbaek Kim, David G. Kirsch · 2015 · Nature Communications
- Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial CellsHirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Kato Mugihiko, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai et al. · 2018 · Cell Reports
- Clonal Hematopoiesis: From Mechanisms to Clinical InterventionThomas Köhnke, Ravindra Majeti · 2021 · Cancer Discovery
- Dissecting Social Cell Biology and Tumors Using Drosophila GeneticsJosé Carlos Pastor-Pareja, Tian Xu · 2013 · Annual Review of Genetics
- Cell competitionNicholas E. Baker · 2011 · Current Biology
- Chronic interleukin-1 exposure triggers selection for
<i>Cebpa</i>
-knockout multipotent hematopoietic progenitorsHiga, Kelly C., Goodspeed, Andrew, Chavez, James S., De Dominici, Marco, Danis, Etienne, Zaberezhnyy, Vadym, Rabe, Jennifer L., Tenen, Daniel G., Pietras, Eric M., DeGregori, James · 2021 · Journal of Experimental Medicine
- Flower-deficient mice have reduced susceptibility to skin papilloma formationEvgeniya Petrova, Jesús M. López-Gay, Christa Rhiner, Eduardo Moreno · 2012 · Disease Models & Mechanisms
- Cell competition in mouse NIH3T3 embryonic fibroblasts controlled by Tead activity and MycHiroshi Mamada, Takashi Sato, Mitsunori Ota, Hiroshi Sasaki · 2015 · Journal of Cell Science
- Regulation and function of p53: A perspective from Drosophila studiesMaria Ingaramo, Juan Sánchez, Andrés Dekanty · 2018 · Mechanisms of Development
- Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non-cell-autonomous processesAndrii I. Rozhok, Jennifer L. Salstrom, James V. DeGregori · 2014 · Aging
- Cell competition and tumor heterogeneityTaylor M. Parker, Vanessa Henriques, Antonio Lopez-beltran B, Harikrishna Nakshatri, Rajan Gogna · 2019 · Seminars in Cancer Biology
- Somatic Mutations in Cardiovascular DiseaseJonathan Brett Heimlich, Alexander G. Bick · 2022 · Circulation Research
- Mutant p53 in cell-cell interactionsSteven E. Pilley, Tristan A. Rodríguez, Karen H. Vousden · 2021 · Genes & Development
- Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivityWang, Yunyuan V., Leblanc, Mathias, Fox, Norma, Mao, Jian-Hua, Tinkum, Kelsey L., Krummel, Kurt, Engle, Dannielle, Piwnica-Worms, David, Piwnica-Worms, Helen, Balmain, Allan et al. · 2011 · Genes & Development
- TP 53 overexpression is an independent adverse prognostic factor in de novo myelodysplastic syndromes with fibrosisSanam Loghavi, Alyaa Al‐Ibraheemi, Zhuang Zuo, Guillermo Garcia‐Manero, Mariko Yabe, Sa A. Wang, Hagop M. Kantarjian, C. Cameron Yin, Roberto N. Miranda, Raja Luthra et al. · 2015 · British Journal of Haematology
- Cell Competition During Growth and RegenerationRajan Gogna, Kevin Shee, Eduardo Moreno · 2015 · Annual Review of Genetics
- Genetic and Genomic Landscape of Secondary and Therapy-Related Acute Myeloid LeukemiaAlexandra S. Higgins, Mithun Vinod Shah · 2020 · Genes
- The Role of the p53 Protein in Stem-Cell Biology and Epigenetic RegulationArnold J. Levine, Anna M. Puzio‐Kuter, Chang S. Chan, Pierre L. Hainaut · 2016 · Cold Spring Harbor Perspectives in Medicine
- Brain Regeneration in Drosophila Involves Comparison of Neuronal FitnessEduardo Moreno, Yuniel Fernández‐Marrero, Patricia Meyer, Christa Rhiner · 2015 · Current Biology
- Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical TranslationSamuele Ferrari, Valentina Vavassori, Daniele Canarutto, Aurélien Jacob, Maria Carmina Castiello, Attya Omer, Pietro Genovese · 2021 · Frontiers in Genome Editing
- Changing mutational and adaptive landscapes and the genesis of cancerL. Alexander Liggett, James V. DeGregori · 2017 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Clonal Hematopoiesis and Its Impact on Cardiovascular DiseaseSoichi Sano, Ying Wang, Kenneth Walsh · 2018 · Circulation Journal
- Myc Function in DrosophilaPaola Bellosta, Peter Gallant · 2010 · Genes & Cancer
- In vitro Culture of Naïve Human Bone Marrow Mesenchymal Stem Cells: A Stemness Based ApproachBidisha Pal, Bikul Das · 2017 · Frontiers in Cell and Developmental Biology
- Mechanisms involved in hematopoietic stem cell agingTakeshi Fujino, Shuhei Asada, Susumu Goyama, Toshio Kitamura · 2022 · Cellular and Molecular Life Sciences
- Expression and Role of p53 in the RetinaLinda Vuong, Shannon M. Conley, Muayyad R. Al‐Ubaidi · 2012 · Investigative Ophthalmology & Visual Science
- Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCTGerbrig Berger, Leonie I. Kroeze, Theresia N. Koorenhof‐Scheele, Aniek O. de Graaf, Kenichi Yoshida, Hiroo Ueno, Yuichi Shiraishi, Satoru Miyano, Eva van den Berg, Hein Schepers et al. · 2018 · Blood
- Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven mannerMeng Wang, Laura T. L. Brandt, Xiaonan Wang, Holly Russell, Emily Mitchell, Ashley N. Kamimae-Lanning, Jill M. Brown, Felix A. Dingler, Juan I. Garaycoechea, Tomoya Isobe et al. · 2023 · Molecular Cell
- Cancer and AgingDaneng Li, Nienke A. de Glas, Arti Hurria · 2015 · Clinics in Geriatric Medicine
- Cell competition: Winning out by losing notchMaria Pilar Alcolea, Philip H. Jones · 2014 · Cell Cycle
- Cell wars: regulation of cell survival and proliferation by cell competitionSilvia Vivarelli, Laura Wagstaff, Eugenia Piddini · 2012 · Essays in Biochemistry
- Imaging innate immune responses at tumour initiation: new insights from fish and fliesYi Feng, Paul B. Martin · 2015 · Nature reviews. Cancer
- BNIP3-mediated mitophagy boosts the competitive growth of Lenvatinib-resistant cells via energy metabolism reprogramming in HCCSikai Wang, Hongxia Cheng, Miaomiao Li, Dongmei Gao, Haoran Wu, Shanshan Zhang, Yilan Huang, Kun Guo · 2024 · Cell Death and Disease
- Therapeutic targeting of the p53 pathway in cancer stem cellsVarun V. Prabhu, Joshua E. Allen, Bo Hong, Shengliang Zhang, Hairong Cheng, Wafik S. El‐Deiry · 2012 · Expert Opinion on Therapeutic Targets
- Cell Competition in CarcinogenesisEsha Madan, António M. Palma, Vignesh Vudatha, Jose Gilberto Trevino, Kedar Nath Natarajan, Robert A. Winn, Kyoung‐Jae Won, Trevor A. Graham, Ronny Drapkin, Stuart A.C. McDonald et al. · 2022 · Cancer Research
- Darwin's multicellularity: from neurotrophic theories and cell competition to fitness fingerprintsEduardo Moreno, Christa Rhiner · 2014 · Current Opinion in Cell Biology
- Field Cancerization in the GI TractTrevor A. Graham, Stuart A.C. McDonald, Nicholas A Wright · 2011 · Future Oncology
- Bcl‐2 proteins in development, health, and disease of the hematopoietic systemMatthias Kollek, Alexandra Müller, Alexander Egle, Miriam Erlacher · 2016 · FEBS Journal
- A potential link between p53, cell competition and ribosomopathy in mammals and in DrosophilaNicholas E. Baker, Marianthi Kiparaki, Chaitali Khan · 2018 · Developmental Biology
- Stem Cell DNA Damage and Genome Mutation in the Context of Aging and Cancer InitiationLara Al Zouabi, Allison J. Bardin · 2020 · Cold Spring Harbor Perspectives in Biology
- The emerging functions of the p53-miRNA network in stem cell biologyLin, Chao-Po, Choi, Yong Jin, Hicks, Geoffrey G., He, Lin · 2012 · Cell Cycle
- Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesisCatherine Hogan, Mihoko Kajita, Kate Lawrenson, Yasuyuki Fujita · 2010 · The International Journal of Biochemistry & Cell Biology
- Tools and Concepts for Interrogating and Defining Cellular IdentityKara L. McKinley, David Castillo‐Azofeifa, Ophir D. Klein · 2020 · Cell stem cell
- Modeling Cutaneous Squamous Carcinoma Development in the MousePhillips Huang, Allan Balmain · 2014 · Cold Spring Harbor Perspectives in Medicine
- Cell competition-induced apical elimination of transformed cells, EDAC, orchestrates the cellular homeostasisShunsuke Kon, Yasuyuki Fujita · 2021 · Developmental Biology
- p53 enables metabolic fitness and self-renewal of nephron progenitor cellsYuwen Li, Jiao Liu, Wencheng Li, Aaron Clifford Brown, Melody Baddoo, Marilyn M. Li, Thomas J. Carroll, Leif H. Oxburgh, Yumei Feng, Zubaida R. Saifudeen · 2015 · Development
- Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cellsWeiwei Liu, Jingwei Jiang, Zeming Li, Yang Xiao, Siyi Zhou, Dehuan Wang, Yi Zou, Tiantian Liu, Ke Li, Huan Liang et al. · 2024 · Theranostics
- The Basally Expressed p53-Mediated Homeostatic FunctionIsha Nagpal, Zhi-Min Yuan · 2021 · Frontiers in Cell and Developmental Biology
- The Biology of Aging and Lymphoma: a Complex InterplayClémentine Sarkozy, Gilles A. Salles, Claire Falandry · 2015 · Current Oncology Reports
- Reactive oxygen species in BCR-ABL1-expressing cells – relevance to chronic myeloid leukemiaJoanna Antoszewska-Smith, Elżbieta Pawłowska, Janusz Błasiak · 2016 · Acta Biochimica Polonica
- The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testisShree Ram Singh, Ying Liu, Jiang‐Sha Zhao, Kevin Xiankun Zeng, Xianyu Steven Hou · 2016 · Nature Communications
- Asymmetric fliesVincent Debat, Frédérique Peronnet · 2013 · Fly
- Therapy-Related Myeloid Neoplasms: Complex Interactions among Cytotoxic Therapies, Genetic Factors, and Aberrant MicroenvironmentDeepak Singhal, Monika Kutyna, Christopher Norman Hahn, Mithun Vinod Shah, Devendra Hiwase · 2024 · Blood Cancer Discovery
- Dynamic stem cell selection safeguards the genomic integrity of the epidermisTomoki Kato, Nan Liu, Hironobu Morinaga, Kyosuke Asakawa, Taichi Muraguchi, Yuko Muroyama, Mariko Shimokawa, Hiroyuki Matsumura, Yuriko Nishimori, Li Jing Tan et al. · 2021 · Developmental Cell
- Aging and Clonal Behavior of Hematopoietic Stem CellsMasayuki Yamashita, Atsushi Iwama · 2022 · International Journal of Molecular Sciences
- TP53 Mutation Analysis in Clinical Practice: Lessons From Chronic Lymphocytic LeukemiaJitka Malčíková, Šárka Pavlová, Kateřina Staňo Kozubík, Šárka Pospı́šilová · 2014 · Human Mutation
- Stem Cell Ageing and ApoptosisStefania Fulle, Lucia Centurione, Rosa Mancinelli, Silvia Sancilio, Francesco A. Manzoli, Roberta Di Pietro · 2012 · Current Pharmaceutical Design
- BIK drives an aggressive breast cancer phenotype through sublethal apoptosis and predicts poor prognosis of ER-positive breast cancerVrajesh Pandya, John Maringa Githaka, Namrata Patel, Richard A. Veldhoen, Judith C. Hugh, Sambasivarao Damaraju, Todd P W McMullen, John Robert Mackey, Ing Swie Goping · 2020 · Cell Death and Disease
- Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53Shaoxiong Chen, Rui Gao, C Yao, Michihiro Kobayashi, Stephen Z. Liu, Mervin C. Yöder, Hal E. Broxmeyer, Reuben Kapur, H. Scott Boswell, Lindsey D. Mayo et al. · 2017 · Leukemia
- CDK19 regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells by suppressing p53-mediated transcription of p21Zihao Zhang, Yukai Lu, Yan Qi, Yang Xu, Song Wang, Fang Chen, Mingqiang Shen, Mo Chen, Naicheng Chen, Lijing Yang et al. · 2022 · Leukemia
- Bone marrow niches for hematopoietic stem cellsAna Luisa Pereira, Serena Galli, César Nombela‐Arrieta · 2024 · HemaSphere
- Tracing the origins of metastasisDon X. Nguyen · 2010 · The Journal of Pathology
- Non‐autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesisMasato Enomoto, John P. Vaughen, Tatsushi Igaki · 2015 · Cancer Science
- Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and AgingOleg N. Timofeev, L Koch, Constantin Niederau, Alina Tscherne, Jean Schneikert, Maria Klimovich, Sabrina Elmshäuser, Markus Alexander Zeitlinger, Marco Mernberger, Andrea Nist et al. · 2020 · Cancer Research
- A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibitionYahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea A. Harrington · 2021 · Aging Cell
- Stem Cells and DNA Damage: Persist or Perish?Andrew A. Lane, David T. Scadden · 2010 · Cell
- Ionizing radiation and hematopoietic malignancies: Altering the adaptive landscapeCourtney J. Fleenor, Andriy Marusyk, James V. DeGregori · 2010 · Cell Cycle
- Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemiaAndrii I. Rozhok, Jennifer L. Salstrom, James V. DeGregori · 2016 · Proceedings of the National Academy of Sciences
- Aging promotes neoplastic disease through effects on the tissue microenvironmentFabio Marongiu, Maria Paola Serra, Silvia Doratiotto, Marcella Sini, Maura Fanti, Erika Cadoni, Monica Serra, Ezio Laconi · 2016 · Aging
- Regulation of proliferation, cell competition, and cellular growth by theDrosophilaJAK-STAT pathwayTamara Zoranovic, Lydia Grmai, Erika A Bach · 2013 · JAK-STAT
- Cell competition and the regulative nature of early mammalian developmentJennifer Nichols, Ana Lima, Tristan A. Rodríguez · 2022 · Cell stem cell
- Distinct landscape and clinical implications of therapy-related clonal hematopoiesisKoichi Takahashi, Daisuke Nakada, Margaret A. Goodell · 2024 · Journal of Clinical Investigation
- Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell ProliferationXiaoli Li, Andrew F. Wilson, Wei Du, Qishen Pang · 2018 · Stem Cell Reports
- Apurinic/Apyrimidinic Endonuclease 2 Is Necessary for Normal B Cell Development and Recovery of Lymphoid Progenitors after Chemotherapeutic ChallengeJeroen E. J. Guikema, Rachel M. Gerstein, Erin K. Linehan, Erin K. Cloherty, Eric Evan‐Browning, Daisuke Tsuchimoto, Yusaku Nakabeppu, Carol E. Schrader · 2011 · The Journal of Immunology
- Engineering cell fitness: lessons for regenerative medicineNika Shakiba, Peter W. Zandstra · 2017 · Current Opinion in Biotechnology
- Loss of Nupr1 promotes engraftment by tuning the quiescence threshold of hematopoietic stem cells via regulation of the p53-checkpoint pathwayTongjie Wang, Chengxiang Xia, Qitong Weng, Kaitao Wang, Yong Dong, Sha Hao, Fang Dong, Xiaofei Liu, Lijuan Liu, Yang Geng et al. · 2020 · Haematologica
- Clonal Architecture and Evolutionary Dynamics in Acute Myeloid LeukemiasMatthieu Duchmann, Lucie Laplane, Raphaël Itzykson · 2021 · Cancers
- Drosophila Models of Cell Polarity and Cell Competition in TumourigenesisNatasha Fahey-Lozano, John E. La Marca, Marta Portela, Helena E. Richardson · 2019 · Advances in experimental medicine and biology
- Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic MusclesKrishnamoorthy Sreenivasan, Alessandro Ianni, Carsten T. Künne, Boris Strilic, S. Günther, Eusebio Perdiguero, Marcus Krüger, S. Spuler, S. Offermanns, Pablo Gómez-del Arco et al. · 2020 · Cell Reports
- Regulation of hematopoietic stem cell integrity through p53 and its related factorsMasayuki Yamashita, Eriko Nitta, Toshio Suda · 2015 · Annals of the New York Academy of Sciences
- Cell Competition Boosts Clonal Evolution and Hypoxic Selection in CancerEsha Madan, Maria Leonor Peixoto, Peter Michael Dimitrion, Timothy D. Eubank, Michail Yekelchyk, Sarmistha Talukdar, Paul B. Fisher, Qing‐Sheng Mi, Eduardo Moreno, Rajan Gogna · 2020 · Trends in Cell Biology
- Role of cell competition in ageingMariana Marques-Reis, Eduardo Moreno · 2021 · Developmental Biology
- SPARC-p53: The double agents of cancerDenise Camacho, Joana P. Jesus, António M. Palma, Sofia A. Martins, Alexandre Afonso, Maria Leonor Peixoto, Christopher James Pelham, Eduardo Moreno, Rajan Gogna · 2020 · Advances in cancer research
- Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibitionNabih Maslah, Emmanuelle Verger, Stéphane Giraudier, Mathias Chéa, Ronald Hoffman, John O Mascarenhas, Bruno Cassinat, Jean‐Jacques Kiladjian · 2022 · Blood Advances
- Spontaneous Cell Competition in Immortalized Mammalian Cell LinesAlfredo Penzo‐Méndez, Yi–Ju Chen, Jinyang Li, Eric S. Witze, Ben Z. Stanger · 2015 · PLoS ONE
- The p53/Adipose-Tissue/Cancer NexusKevin J. Zwezdaryk, Deborah E. Sullivan, Zubaida R. Saifudeen · 2018 · Frontiers in Endocrinology
- How to address second and therapy‐related acute myelogenous leukaemiaCaspian H. Oliai, Gary John Schiller · 2019 · British Journal of Haematology
- Cellular reprogramming in skin cancerIhn Young Song, Allan Balmain · 2014 · Seminars in Cancer Biology
- Stem cell competition driven by the Axin2-p53 axis controls brain size during murine developmentXuelian Sun, Zhenhua Chen, Xize Guo, Jingjing Wang, Mengmeng Ge, Samuel Zheng Hao Wong, Ting Wang, Si Li, Mingze Yao, Laura A. Johnston et al. · 2023 · Developmental Cell
- CHIP: a clonal odyssey of the bone marrow nicheWolfgang E. Schleicher, Bridget Hoag, Marco De Dominici, James V. DeGregori, Eric Martin Pietras · 2024 · Journal of Clinical Investigation
- Ionizing Radiation Leads to the Replacement and de novo Production of Colonic Lgr5 Stem CellsKensuke Otsuka, Nobuyuki Hamada, Junji Magae, Hideki Matsumoto, Yuko Hoshi, Toshiyasu Iwasaki · 2013 · Radiation Research
- Transcriptional versus metabolic control of cell fitness during cell competitionKaterina Lawlor, Salvador Pérez-Montero, Ana Lima, Tristan A. Rodríguez · 2019 · Seminars in Cancer Biology
- Network Pharmacology‐Based Investigation of the System‐Level Molecular Mechanisms of the Hematopoietic Activity of Samul‐Tang, a Traditional Korean Herbal FormulaHo-Sung Lee, In-Hee Lee, Sang‐In Park, Dae-Yeon Lee · 2020 · Evidence-based Complementary and Alternative Medicine
- Cell competition from development to neurodegenerationMaria Carolina RODRIGUES, Joana Couceiro, Eduardo Moreno · 2021 · Disease Models & Mechanisms
- Programmed cell death and tissue regeneration: a link that should be resolvedGelina S. Kopeina, Anastasia Yu. Efimenko, Tkachuk Va, Boris Zhivotovsky · 2025 · Physiological Reviews