Rejuvenation of Regeneration in the Aging Central Nervous System

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Items 301–400 of 648

1. Systemic milieu and age-related deterioration
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3. Age-dependent decline in remyelination capacity is mediated by apelin–APJ signaling
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4. Replenishing the Aged Brains: Targeting Oligodendrocytes and Myelination?
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5. Purinergic neurone-glia signalling in cognitive-related pathologies
   Péter Illés, Alexei Verkhratsky · 2015 · Neuropharmacology
6. Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination
   Francisco J. Rivera, Alerie Guzman de la Fuente, Chao Zhao, Maria Elena Silva, Ginez A. González, Roman Wodnar, Martina Feichtner, Simona Lange, Oihana Errea, Eleni Priglinger et al. · 2019 · Glia
7. Features, Fates, and Functions of Oligodendrocyte Precursor Cells
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8. Modeling motor neuron disease: the matter of time
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9. Aging insights from heterochronic parabiosis models
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10. The systemic milieu as a mediator of dietary influence on stem cell function during ageing
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11. Delayed Nerve Stimulation Promotes Axon-Protective Neurofilament Phosphorylation, Accelerates Immune Cell Clearance and Enhances Remyelination In Vivo in Focally Demyelinated Nerves
    Nikki A. McLean, Bogdan F. Gh. Popescu, Tessa Gordon, Douglas William Zochodne, Valerie M. K. Verge · 2014 · PLoS ONE
12. Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis
    Hampton, David W, Serio, Andrea, Pryce, Gareth, Al-Izki, Sarah, Franklin, Robin JM, Giovannoni, Gavin, Baker, David, Chandran, Siddharthan · 2013 · Acta Neuropathologica Communications
13. Double Roles of Macrophages in Human Neuroimmune Diseases and Their Animal Models
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14. Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative disease
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15. A Matter of State: Diversity in Oligodendrocyte Lineage Cells
    Yasmine Kamen, Helena Pivoňková, Kimberley Anne Evans, Ragnhildur Thóra Káradóttir · 2021 · The Neuroscientist
16. Multiple Sclerosis
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17. Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming
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18. Microglia Impede Oligodendrocyte Generation in Aged Brain
    Weimin Luan, Xiqian Qi, Feng Liang, Xiaotao Zhang, Ziyang Jin, Ligen Shi, Benyan Luo, Xuejiao Dai · 2021 · Journal of Inflammation Research
19. Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery
    Pauline E. M. van Schaik, Inge S. Zuhorn, Wia Baron · 2022 · International Journal of Molecular Sciences
20. Navigating oligodendrocyte precursor cell aging in brain health
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21. Astrocyte-derived clusterin disrupts glial physiology to obstruct remyelination in mouse models of demyelinating diseases
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22. IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
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23. Nutritional factors and aging in demyelinating diseases
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24. Role of Cell-Intrinsic and Environmental Age-Related Changes in Altered Maintenance of Murine T Cells in Lymphoid Organs
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25. Aging as a loss of morphostatic information: A developmental bioelectricity perspective
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26. Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis
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27. Accelerated aging-related transcriptome alterations in neurovascular unit cells in the brain of Alzheimer’s disease
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28. Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination
    Aida V. Garcia Corrales, Sanne G. S. Verberk, Mansour Haidar, Elien Grajchen, Jonas Dehairs, Sam Vanherle, Melanie Loix, Tine Weytjens, Pascal Gervois, Takashi Matsuzaka et al. · 2023 · Proceedings of the National Academy of Sciences
29. Impacts of systemic milieu on cerebrovascular and brain aging: insights from heterochronic parabiosis, blood exchange, and plasma transfer experiments
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30. In vivo assessment of behavioral recovery and circulatory exchange in the peritoneal parabiosis model
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31. The Effects of Parabiosis on Aging and Age-Related Diseases
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32. MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
    Masashi Fukuoka, Hiromi Fujita, Kosumo Numao, Yasuko Nakamura, Hideo Shimizu, Masayuki Sekiguchi, Hirohiko Hohjoh · 2021 · Communications Biology
33. A cord blood monocyte–derived cell therapy product accelerates brain remyelination
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34. The immune landscape of murine skeletal muscle regeneration and aging.
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35. Rejuvenation: It’s in Our Blood
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36. Aged Mice Repeatedly Injected with Plasma from Young Mice: A Survival Study
    Dmytro W. Shytikov, Olexiy Balva, Edouard H Debonneuil, Pavel Glukhovskiy, Iryna Pishel · 2014 · BioResearch open access
37. Young plasma attenuates age‐dependent liver ischemia reperfusion injury
    Anding Liu, Jiankun Yang, Qi Zhou Hu, Olaf Dirsch, Uta Dahmen, Cuntai Zhang, David A. Gewirtz, Haoshu Fang, Jian Sun · 2018 · The FASEB Journal
38. Beyond Clotting: A Role of Platelets in CNS Repair?
    Francisco J. Rivera, I. Kazanis, C. Ghevaert, L. Aigner · 2016 · Frontiers in Cellular Neuroscience
39. Impaired regeneration in aged nerves: Clearing out the old to make way for the new
    Jami L. Scheib, Ahmet Höke · 2016 · Experimental Neurology
40. A young testicular microenvironment protects Leydig cells against age‐related dysfunction in a mouse model of premature aging
    Michael K. Curley, Laura Milne, Sarah E. Smith, Anne J⊘rgensen, Hanne Winther Frederiksen, Patrick W. F. Hadoke, Paul K Potter, Lee B. Smith · 2018 · The FASEB Journal
41. Csf1 Deficiency Dysregulates Glial Responses to Demyelination and Disturbs CNS White Matter Remyelination
    Wylot, Bartosz, Mieczkowski, Jakub, Niedziolka, Sylwia, Kaminska, Bozena, Zawadzka, Malgorzata · 2019 · Cells
42. DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice
    G. J. Huang, Zhidan Li, Xuezhao Liu, Menglong Guan, Songlin Zhou, Xiaowen Zhong, Tao Zheng, Dazhuan Eric Xin, Xiaosong Gu, Dezhi Mu et al. · 2024 · Nature Neuroscience
43. Predictors of response to opicinumab in acute optic neuritis
    Diego Cadavid, Laura Joan Balcer, Steven L. Galetta, Orhan Aktaş, Tjalf Ziemssen, Ludo J. Vanopdenbosch, Letizia Leocani, Mark Steven Freedman, Gordon Terence Plant, Jana Lizrova Preiningerova et al. · 2018 · Annals of Clinical and Translational Neurology
44. VEGF promotes tendon regeneration of aged rats by inhibiting adipogenic differentiation of tendon stem/progenitor cells and promoting vascularization
    Fan Lai, Jingjing Wang, Hong Tang, Pan Huang, Juan Liu, Gang He, Mei Zhou, Xu Tao, Kanglai Tang · 2022 · The FASEB Journal
45. Progenitor cell-based treatment of glial disease
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46. Extracellular vesicle‐associated cholesterol supports the regenerative functions of macrophages in the brain
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47. Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide
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48. Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters
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49. Monocytes in central nervous system remyelination
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50. Impaired metabolism of oligodendrocyte progenitor cells and axons in demyelinated lesion and in the aged CNS
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51. Adipose tissue aging: An update on mechanisms and therapeutic strategies
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52. Susceptibility to acute cognitive dysfunction in aged mice is underpinned by reduced white matter integrity and microgliosis
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53. Remyelinating strategies in multiple sclerosis
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54. Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation
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55. Stepwise impairment of neural stem cell proliferation and neurogenesis concomitant with disruption of blood-brain barrier in recurrent ischemic stroke
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56. Comparative analysis of neuroinflammatory pathways in Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis: insights into similarities and distinctions
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57. How Necessary is the Vasculature in the Life of Neural Stem and Progenitor Cells? Evidence from Evolution, Development and the Adult Nervous System
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58. A Perspective on Roles Played by Immunosenescence in the Pathobiology of Alzheimer's Disease
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59. Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination
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60. Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway
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61. Distinct origins, gene expression and function of microglia and monocyte-derived macrophages in CNS myelin injury and regeneration
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62. FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms
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63. The effect of age on stem cell function and utility for therapy
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64. The Current Challenges for Drug Discovery in CNS Remyelination
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65. Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration
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66. Remyelination in animal models of multiple sclerosis: finding the elusive grail of regeneration
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67. Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit
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68. Remyelination: A Potential Therapeutic Strategy for Alzheimer’s Disease?
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69. The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke
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70. Remyelination in humans due to a retinoid‐X receptor agonist is age‐dependent
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71. The Impact of Aging on Multiple Sclerosis
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72. Current status of myelin replacement therapies in multiple sclerosis
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73. Inhibitory milieu at the multiple sclerosis lesion site and the challenges for remyelination
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74. Exosome Cargo in Neurodegenerative Diseases: Leveraging Their Intercellular Communication Capabilities for Biomarker Discovery and Therapeutic Delivery
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75. Dynamic Aging: Channeled Through Microenvironment
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76. The rejuvenating influence of young plasma on aged intestine
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77. Therapeutic Apheresis: Why?
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78. Immune control of brain physiology
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79. Live imaging of remyelination in the adult mouse corpus callosum
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80. The effect of young blood plasma administration on gut microbiota in middle-aged rats
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81. Anti‐ and pro‐inflammatory milieu differentially regulate differentiation and immune functions of oligodendrocyte progenitor cells
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82. Hyperbaric oxygen therapy: future prospects in regenerative therapy and anti-aging
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83. Overview of emerging therapies for demyelinating diseases
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84. Regenerative Medicines for Remyelination: From Aspiration to Reality
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85. Neurogenesis in the Adult Mammalian Brain: How Much Do We Need, How Much Do We Have?
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86. Mediation of Protection and Recovery From Experimental Autoimmune Encephalomyelitis by Macrophages Expressing the Human Voltage-Gated Sodium Channel NaV1.5
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87. Myelin and traumatic brain injury: The copper deficiency hypothesis
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88. New Trends in Aging Drug Discovery
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89. Neutrophils promote clearance of nuclear debris following acid-induced lung injury
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90. Niche science
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91. Aging and neoteny in the B lineage
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92. Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits
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93. CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance
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94. Heterogeneity in oligodendrocyte precursor cell proliferation is dynamic and driven by passive bioelectrical properties
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95. Stepchild or Prodigy? Neuroprotection in Multiple Sclerosis (MS) Research
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96. GDF11 administration does not extend lifespan in a mouse model of premature aging
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97. Why monkeys do not get multiple sclerosis (spontaneously)
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98. Acquired demyelination but not genetic developmental defects in myelination leads to brain tissue stiffness changes
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99. Role of circulating factors in cardiac aging
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100. Myelin Quantification in White Matter Pathology of Progressive Multiple Sclerosis Post-Mortem Brain Samples: A New Approach for Quantifying Remyelination
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