Neural Subtype Specification from Human Pluripotent Stem Cells
Cited by (287)
Items 201–287 of 287
- A roadmap for neurodevelopmental disease modeling for non-stem cell biologistsCarl Ernst · 2020 · Stem Cells Translational Medicine
- Spinal cord extracts from injured spinal cord impede differentiation of rat embryonic neural stem cells into neurons through regulating Notch signaling pathway.Xiaolan Feng, Ge Zhang, Daxiong Feng, Xufeng Jia, Qingzhong Zhou · 2019 · Europe PMC (PubMed Central)
- Comprehensive profiling of transcription factors for reprogramming human astrocytes to neuronal cells through endogenous CRISPR-based gene activationSamuel J. Reisman, Dahlia Halabi, Samantha E. Miller, Lingyun Song, Sara Geraghty, Nicholas Sangvai, Grayson Rice, Alexias Safi, Gregory E. Crawford, Charles A. Gersbach · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Functional recovery through the plastic adaptation of organoid grafts in cortical tissueJuraj Ondriš, J. Schwamborn, U. Olcese · 2025 · Cellular and Molecular Life Sciences
- Neurons in a Dish: A Review of In Vitro Cell Models for Studying NeurogenesisMariana Vassal, Ana Campos Cruz, Sandra Rebelo, Filipa Martins · 2026 · Journal of Neurochemistry
- A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytesJacob Knittel, Gayathri Rajaram Srinivasan, Carlye Frisch, Nicholas Brookhouser, Sreedevi Raman, Albert Essuman, David A. Brafman · 2022 · STAR Protocols
- Regenerating the Senses: Stem Cell‐Derived Sensory Neurons and Functional Genomics in Neurological DisordersPushpanathan Muthuirulan, Avanthika Nityanand, Anjali Pandit, Vaishnavi Gururajan · 2025 · Sensory Neuroscience
- Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptomsXing Jiang, Zhimin Lu, Qinglu Wang, Ying Luo, Jie Zhang · 2025 · World Journal of Stem Cells
- Dysregulation of glutamatergic and GABAergic neurons in Treatment-Resistant Depression: Insights from patient-derived neuronsZaira Tomasoni, Federica Bono, Giulia Sbrini, Adele Guglielmi, Veronica Mutti, Jessica Mingardi, Laura Musazzi, Alice Filippini, Sergio Ferraboli, Cristina Missale et al. · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Neural Tube Patterning: From a Minimal Model for Rostrocaudal Patterning Towards an Integrated 3D ModelMax Brambach, Ariane Ernst, Sara Nolbrant, Janelle Drouin‐Ouellet, Agnete Kirkeby, Malin Parmar, Victor Olariu · 2020 · iScience
- Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical developmentEmma LaNoce, Daniel Y. Zhang, Alan Garcia-Epelboim, Yijing Su, Yusha Y. Sun, Giana Alepa, Angelina R. Angelucci, Cagla Akay, Kelly L. Jordan‐Sciutto, Hongjun Song et al. · 2024 · Frontiers in Molecular Neuroscience
- Autophagy Dysfunction as a Phenotypic Readout in hiPSC-Derived Neuronal Cell Models of Neurodegenerative DiseasesCongxin Sun, Tatiana Rosado Rosenstock, Malkiel A. Cohen, Sovan Sarkar · 2021 · Methods in molecular biology
- Spinal interneurons and cell transplantationAshley Tucker, Miriam Aceves, Jessica C. Butts, Jennifer N. Dulin · 2022 · Elsevier eBooks
- Recent Advancements in Engineering Strategies for Manipulating Neural Stem Cell BehaviorBrian J. O’Grady, Ethan S. Lippmann · 2020 · Current Tissue Microenvironment Reports
- Neural induction of embryonic stem/induced pluripotent stem cellsAnindita Sarkar, Maria Carolina Marchetto, Fred H. Gage · 2020 · Elsevier eBooks
- Two parallel lineage-committed progenitors contribute to the developing brainCarolyn E. Dundes, Rayyan Trebonias Jokhai, Hadia S. Ahsan, Rachel S. Kang, Rachel E.A. Salomon, Arjun Rajan, Yoon Seok Kim, Liam J. Stanton, Christine L. Xu, Stephanie Do et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Skin irritation testing using human iPSCs derived 3D skin equivalent modelHyewon Shin, Se-Eun Kim, C‐Yoon Kim, Suemin Lee, Ji-Heon Lee, Jieun Baek, Gujin Chung, Min Woo Kim, Jeong-Seop Oh, Shinhye Park et al. · 2025 · PLoS ONE
- Induced pluripotent stem cells carrying novel APTX mutations presented defective neural differentiation with the accumulation of DNA single-strand breaksZirui Chen, Yihua Huang, Zhirong Yuan, Kaibiao Xu, Yuqing Guan, Luqin Wang, Yawei Jiang, Weiling Deng, Yue Pan, Jing Liu et al. · 2025 · Cell Death Discovery
- Advancements in differentiation of induced pluripotent stem cells into specialized neuronal subtypesSelena Setsu, Hideyuki Okano, Satoru Morimoto · 2025 · Neural Regeneration Research
- METTL3 and METTL14 determine human neural fate specificationsYanqi Zhang, Jitian Zhang, Huaisong Lin, Junwei Wang, Qianyu Chen, Tiancheng Zhou, Qi Xing, Guangjin Pan, Yongli Shan · 2025 · Nucleic Acids Research
- Update on the interaction of notch and Wnt/β-catenin signaling in neural stem cells and brain homeostasis during ischemic strokeMahsa Hasanzadeh‐Moghadam, Daryoush Mohammdnejad, Reza Rahbarghazi, Javad Mahmoudi, Ali Hassanzadeh, Vida Mafikandi, Hamid Taiefi Nasrabadi, Mohammad Karimipour · 2026 · Tissue and Cell
- Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case reportHuiping Li, Fang Yuan, Yaming Du, Tao Pan, Wanxin Wen, Shaoxue Li, Lixin Wang, Aili Lu · 2021 · Journal of Medical Case Reports
- Translational research in spinal cord injury – What is in the future?Nader Hejrati, William Brett McIntyre, Katarzyna Pieczonka, Sophie Ostmeier, Christopher S. Ahuja, Brian K. Kwon, Alexander Richard Vaccaro, F. Cumhur Öner, Michael George Fehlings · 2022 · Elsevier eBooks
- Role of the cytoskeleton and membrane trafficking in axon–dendrite morphogenesisKevin C. Flynn, Frank Bradke · 2020 · Elsevier eBooks
- Wrap it up: myelination of transplanted neurons for repairMaría Fernanda Martínez-Reza, Magdalena Götz · 2025 · Frontiers in Cellular Neuroscience
- Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal ModelYue Tian, Yi‐Chun Ou, Zi-Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing · 2026 · Advanced Science
- Stem cells as emerging regenerative approaches for post-traumatic stress disorder: Mechanisms and translational challengesChin-Yee Nicole Thong, Yeannie H. Y. Yap · 2026 · Brain Research
- An integrated sensing disease modeling platform for in situ monitoring of glutamate neurotransmitter using hiPSC-derived neurons and MNP@ZIF-8/ENZKeyang Feng, Da Wang, Yufan Zhang, Dini Zou, Xinyue Zhang, Chu Chu, Yan Liu, Min Xu, Wanying Zhu · 2026 · Sensors and Actuators B Chemical
- Rapid and Robust Generation of Human Cortical Interneurons from Induced Neural Stem CellsXinwei Zang, Yunqian Guan, Wanting Xing, Zhiguo Chen · 2026 · International Journal of Molecular Sciences
- Two parallel neural ectoderm progenitors contribute to the developing brainRayyan Trebonias Jokhai, Carolyn E. Dundes, Hadia S. Ahsan, Rachel S. Kang, Rachel E.A. Salomon, Arjun Rajan, Yoon Seok Kim, Liam James Stanton, Christine L. Xu, Stephanie Do et al. · 2026 · Nature Neuroscience
- Ultrastructural Organization of Ventral Mesencephalic Neurons Derived from Human Induced Pluripotent Stem CellsKristina A. Kutukova, Lidia E. Frumkina, Mikhail V. Ivanov, Ekaterina V. Novosadova, В. В. Симонова, Stanislav A. Antonov, Igor A. Grivennikov, Sergey Nikolaevich Illarioshkin, Л. Г. Хаспеков · 2020 · Human Physiology
- Expansion of Human Pluripotent Stem Cells in Stirred Tank BioreactorsMarites T. Woon, Puspa Raj Pandey, Inbar Friedrich Ben‐Nun · 2021 · Methods in molecular biology
- Harnessing the Power of Stem Cell Models to Study Shared Genetic Variants in Congenital Heart Diseases and Neurodevelopmental DisordersXuyao Chang, Mingxia Gu, Jason H. Tchieu · 2022 · Cells
- Real-time thiol detection in iPSC-derived neuron cultures using SemKur-IM, a novel fluorescent dithio probeRoxanne E. Alvarez, Jayson Kurfis, Michael L. Hendrickson, Daniel S. Sem · 2023 · SLAS DISCOVERY
- Anti-obesity compounds, Semaglutide and LiPR, and PrRP do not change the proportion of human and mouse POMC+ neuronsSara K. M. Jörgensen, May Surridge-Smith, Kimberley M. Jones, Lenka Maletı́nská, Nicholas D. Allen, David Petřík · 2025 · PLoS ONE
- Modeling Down Syndrome Neurodevelopment with Dosage CompensationJan T. Czerminski · 2019 · eScholarship@UMassChan
- Exploring the biological domain of the neural embryonic stem cell test (ESTn): Morphogenetic regulators, Hox genes and cell types, and their usefulness as biomarkers for embryotoxicity screeningVictoria C. de Leeuw, Jeroen L. A. Pennings, Ellen V.S. Hessel, Aldert H. Piersma · 2021 · Toxicology
- Cerebral Organoids in Developmental NeuroscienceAndrea Forero, Silvia Cappello · 2022 · Springer eBooks
- Deciphering the protein dynamics and molecular determinants of iPSC-derived neuronsSuzy Varderidou‐Minasian, Philipp Schätzle, Casper C. Hoogenraad, R. Jeroen Pasterkamp, Maarten A. F. Altelaar · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Modeling Neurodegenerative/Neurodevelopmental Disorders using Human-Derived Pluripotent Stem CellsKaivalya Shevade · 2023 · Preprints.org
- Sensorimotor Organoids for Neuromuscular DiseaseJoão D. Pereira, Anna‐Claire Devlin, Daniel M. DuBreuil, Yechiam Sapir, Eugene Berezovski, Vignesh Chander, Brian Waigner · 2019 · SSRN Electronic Journal
- Generation and characterisation of human cortical interneurons reporter stem cell linesCruz Santos, Maria Luisa Rodrı́guez de la Concepción · 2019 · ORCA Online Research @Cardiff (Cardiff University)
- From human pluripotent stem cells to cerebral cortical neuronsRoxana Deleanu · 2021 · Elsevier eBooks
- The Development and Application of a Human Stem Cell-Based Model of Chemotherapy-Induced NeuropathyAndrew R. Snavely · 2018 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
- Induced pluripotent stem cells for modeling schizophrenia pathogenesisPeiyan Ni, Sangmi Chung · 2021 · Elsevier eBooks
- PiggyBac vectors in pluripotent stem cell research and applicationsMaria Giovanna Garone, Alessandro Rosa · 2021 · Elsevier eBooks
- Use of human induced pluripotent stem cells (hiPSC)-derived neuronal models to study the neuropathogenesis of the protozoan parasite, Toxoplasma gondiiSandra K. Halonen · 2021 · Elsevier eBooks
- Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and findingsFernanda Majolo, Daniel Rodrigo Marinowic, Pâmella Nunes Azevedo, Guilherme Liberato da Silva, Denise Cantarelli Machado, Jaderson Costa DaCosta · 2021 · Elsevier eBooks
- Pluripotent stem cell–derived brain-region-specific organoidsPhuong Trang Nguyen, Hongjun Song, Guo‐li Ming · 2021 · Elsevier eBooks
- Modeling hereditary spastic paraplegias using induced pluripotent stem cellsYongchao Mou, Zhen‐Yu Chen, Xue-Jun Li · 2021 · Elsevier eBooks
- Induced pluripotent stem cell–derived neural stem cellsLars Roll, Andréas Faissner · 2021 · Elsevier eBooks
- Toward Construction of a Brain in a Dish: Cultured Neurons, Brain Organoids, and BeyondYoshiho Ikeuchi · 2021 · The Brain & Neural Networks
- Methodology of neuronal pluripotent stem cell of in vitro difference process as an alternative therapy of neurodegenerative diseaseWahyuni Wulansari, Fuad Gandhi Torizal, Annisa Khumaira, Ika Afifah Nugraheni · 2022 · JHeS (Journal of Health Studies)
- Applications of Neural Organoids in Neurodevelopment and Regenerative MedicineJing Gong, Jiahui Kang, Minghui Li, Xiao Liu, Jun Yang, Haiwei Xu · 2022 · Biomedical engineering
- Faculty Opinions recommendation of JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells.Vijay Kumar Tiwari, Arun Mariappan · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Quantitative mass spectrometry-based proteomics in the study of iPSC-derived neurons and disease modelingSouzanna Varderidou · 2022 · Utrecht University Repository (Utrecht University)
- Cerebral Organoids in Developmental NeuroscienceAndrea Forero, Silvia Cappello · 2022 · Springer eBooks
- Developing clinically translatable screens using iPSC-derived neural cellsSandra J. Engle, Patrick W. Faloon, Abigail Mariga, Robin J. Kleiman · 2022 · Elsevier eBooks
- Stem cell programming – prospects for perinatal medicineLea Jessica Berg, Oliver Brüstle · 2023 · Journal of Perinatal Medicine
- In Vitro Nervous Tissue Culture Methods: a Brief ReviewDavit Ghazaryan, Naira M. Ayvazyan · 2023 · “Katchar” Collection of Scientific Articles International Scientific-Educational Center NAS RA
- Analysis of autophagy deficiency and cytotoxicity in autophagy-deficient human embryonic stem cell-derived neuronsMiriam E. Korsgen, CongXin Sun, Elena Seranova, M. Zatyka, Dewi Astuti, Tetsushi Kataura, Timothy Barrett, V. Korolchuk, Sovan Sarkar · 2023 · STAR Protocols
- Translational control contribution to human neuronal gene expressionÉrico Moreto Lins · 2021
- Human amniotic epithelial stem cell-derived dopaminergic neuron-like cells ameliorate motor dysfunction in a rat model of Parkinson's diseaseTuoying Jiang, Jian‐An Huang, Bo Xu, Zhen Ge, Yi Li, Leiting Wei, Luyang Yu, Jinying Li · 2024 · Life Sciences
- Human Induced Pluripotent Stem Cell–Derived Neuronal Cell Cultures in Drug Discovery and DevelopmentOlaf H.-U. Schroeder, Luise Schultz, Anne‐Marie Knospe, Maria Winkler, Dieter G. Weiss, Konstantin Jügelt · 2024 · Springer eBooks
- Utilization of human stem cells to examine neurotoxic impacts on differentiationVictoria C. de Leeuw, Ellen V.S. Hessel · 2024 · Advances in neurotoxicology
- The long road to the development of stem cells as a model for central nervous system health and diseaseHyunjin Kim, Aaron B. Bowman · 2024 · Advances in neurotoxicology
- Deciphering the Pathophysiological Mechanisms Underpinning Myoclonus Dystonia Using Pluripotent Stem Cell-Derived Cellular ModelsZongze Li, Laura Abram, Kathryn J. Peall · 2024 · Cells
- Introduction to stem cell biology and its role in treating neurologic disordersMalin Parmar, Anselme L. Perrier · 2024 · Handbook of clinical neurology
- Human Induced Pluripotent Stem Cell–Derived Neuronal Cell Cultures in Drug Discovery and DevelopmentOlaf H.-U. Schroeder, Luise Schultz, Anne‐Marie Knospe, Maria Winkler, Dieter G. Weiss, Konstantin Jügelt · 2024 · Springer eBooks
- Anti-obesity compounds, Semaglutide and LiPR, do not change the proportion of human and mouse POMC+ neuronsSara K. M. Jörgensen, May Surridge-Smith, Kimberley M. Jones, Lenka Maletı́nská, Nicholas D. Allen, David Petřík · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Human induced pluripotent stem cell-derived astrocyte and neuron co-culture model for neuroinflammation modelingBoning Qiu, Massimiliano Caiazzo · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Characterization of Neural Stem Cells of the Human Embryonic Fetus Across Regions of the Central Nervous System and Through Standard Gestation Period AssessmentsYu Mi Park, Hyun Young Kim · 2025 · Developmental Neurobiology
- Neurological DisordersDheeraj Sharma, Shriyansh Srivastava · 2025 · Wiley eBooks
- Geometrical constraints dictate assembly and phenotype of human iPSC-derived motoneuronal spheroidsEleonora Mello, Stefano Sorrentino, Alessio Bucciarelli, Ermanno Cordelli, Elisa De Luca, Haakon B. Nygaard, Stefan Wendt, Alberto Rainer, Giuseppe Gigli, Lorenzo Moroni et al. · 2025 · Stem Cell Research & Therapy
- Neural Stem CellsGerd Kempermann · 2025 · Oxford University Press eBooks
- Application of brain organoids in Huntington's diseaseRoselin Gnanarajan, Nandita Ravichandran, Panimalar Abirami Karuppusamy, Deenathayalan Uvarajan, Arul Narayanasamy · 2025 · Elsevier eBooks
- Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward ProgrammingLingling Zhu, Wei‐Guang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan et al. · 2025 · Advanced Science
- The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem CellsZachary Jordan, Anukriti Singh, Seth Kattapong‐Graber, Sonal Goswami, Neville E. Sanjana, Emanuela Zuccaro, Feng Zhang, Kevin C. Eggan, Jenny Hsieh, Brian P. Hermann et al. · 2025 · Stem Cells and Development
- Additional file 1 of Chenodeoxycholic acid rescues axonal degeneration in induced pluripotent stem cell-derived neurons from spastic paraplegia type 5 and cerebrotendinous xanthomatosis patientsMou, Yongchao, Ghata Nandi, Sukhada Mukte, Eric Chai, Chen, Zhenyu, Jørgen E Nielsen, Troels T. Nielsen, Criscuolo, Chiara, Craig D. Blackstone, Matthew J. Fraidakis et al. · 2023 · Figshare
- Protocol for combining BMP, MEK, WNT inhibition and iNGN2 to enable rapid neuronal differentiation and regional patterning from hiPSCsCarina Habich, Astrid Doering, Justine D. Manos, Miroslav Cik, Peter Reinhardt · 2026 · STAR Protocols
- Cellular modelling of a new type of Pontocerebellar Hypoplasia caused by a defect in the multiple inositol-polyphosphate phosphatase 1 geneEkin Ucuncu · 2020 · theses.fr (ABES)
- Altered neuronal activity in the hippocampal CA3 region in an in vitro model of tauopathyAnia Goncalves · 2020 · theses.fr (ABES)
- A patient-specific induced pluripotent stem cell and neural stem cell resource for angelman syndrome with 15q11.2-q13 deletionSong Qu, Y J Wu, Pu Sun, Song Cui, Yanyan Wang · 2026 · Scientific Reports
- Decoding glioblastoma evolution and heterogeneity through mechanistic modeling: implications for clinical translationHaowu Jiang, Weidong Zhao, Hui Zhou, Rui Sun · 2026 · Journal of Experimental & Clinical Cancer Research
- Presynaptic mechanism of epileptiform activities in forward-programmed human excitatory neuronal networksJianbin Wen, Jiaqing Li, Michael Peitz, Oliver Bruestle · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Critical developmental windows amplify neurotoxicity in human dopaminergic neurons via hedgehog and cAMP pathway disruptionShichang Li, Miaomiao Zhao, Shuxian Zhang, Renjun Yang, Yang Zhang, Nuoya Yin, Magdalena J. Koziol, Francesco Faiola · 2026 · Journal of Environmental Sciences
- Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated ExcitabilityJin-Chul Ahn, Minseop Kim, Ju-Hee Kim, Seok‐Hyeon Kang, Da-In Lee, Huiwen Liu, Seoungyul Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong et al. · 2026 · Advanced Materials