In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity
Zhang, Kun, Zhang, Ludi, Liu, Wenming, Ma, Xiaolong, Cen, Jin, Sun, Zhen, Wang, Chenhua, Feng, Sisi +13 more·2018·Cell Stem Cell
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- Recent Advances in Regenerative Medicine of the Liver and Bile Duct System by Chemically Induced Liver Progenitor Cells (CLiPs) in Nagasaki ExperienceMasaaki Hidaka, Daisuke Miyamoto, Susumu Eguchi · 2024 · Springer eBooks
- Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functionsArif Ibrahim Ardisasmita, Indi P. Joore, N. Levy, Adam Myszczyszyn, Ary Marsee, Theo L. Sinnige, Jos P.N. Ruiter, Sacha Ferdinandusse, Oksana Y. Dudaryeva, E. Gruber et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
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- Additional file 3 of Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapyMa, Chen, Zhang, Ludi, He, Ting, Huiying Cao, Xiongzhao Ren, Ma, Chenhui, Yang, Jiale, Huang, Ruimin, Pan, Guoyu · 2021 · Figshare
- Additional file 1 of CD24+LCN2+ liver progenitor cells in ductular reaction contributed to macrophage inflammatory responses in chronic liver injuryHuang, Wei-Jian, Qiu, Bi-Jun, Qi, Xiao-Shu, Chen, Cai-Yang, Liu, Wen-Ming, Zhou, Shen-ao, Ding, Min, Lu, Feng-Feng, Zhao, Jie, Dan Tang et al. · 2023 · Figshare
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- Additional file 3 of Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liverRen, Jilong, Yu, Dawei, Wang, Jing, Xu, Kai, Xu, Yanan, Sun, Renren, An, Peipei, Li, Chongyang, Feng, Guihai, Zhang, Ying et al. · 2022 · Figshare
- Additional file 1 of Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liverRen, Jilong, Yu, Dawei, Wang, Jing, Xu, Kai, Xu, Yanan, Sun, Renren, An, Peipei, Li, Chongyang, Feng, Guihai, Zhang, Ying et al. · 2022 · Figshare
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- Additional file 2 of High-efficiency c-Myc-mediated induction of functional hepatoblasts from the human umbilical cord mesenchymal stem cellsDeng, Jie, Luo, Kai, Xu, Pengchao, Jiang, Qingyuan, Wang, Yuan, Yunqi Yao, Chen, Xiaolei, Fuyi Cheng, Dan Xie, Deng, Hongxin · 2021 · Figshare
- Additional file 2 of Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapyMa, Chen, Zhang, Ludi, He, Ting, Huiying Cao, Xiongzhao Ren, Ma, Chenhui, Yang, Jiale, Huang, Ruimin, Pan, Guoyu · 2021 · Figshare
- Additional file 4 of Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapyMa, Chen, Zhang, Ludi, He, Ting, Huiying Cao, Xiongzhao Ren, Ma, Chenhui, Yang, Jiale, Huang, Ruimin, Pan, Guoyu · 2021 · Figshare
- Additional file 1 of Integration of ATAC-Seq and RNA-Seq reveals FOSL2 drives human liver progenitor-like cell aging by regulating inflammatory factorsDing, Min, Huang, Weijian, Liu, Guifen, Bo Zhai, Yan, Hexin, Zhang, Yong · 2023 · Figshare
- Additional file 1 of Robust expansion and functional maturation of human hepatoblasts by chemical strategyTingcai Pan, Tao, Jiawang, Chen, Yan, Zhang, Jiaye, Anteneh Getachew, Yuanqi Zhuang, Wang, Ning, Xu, Yingying, Shenglin Tan, Fang, Ji et al. · 2021 · Figshare
- Additional file 1 of Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapyMa, Chen, Zhang, Ludi, He, Ting, Huiying Cao, Xiongzhao Ren, Ma, Chenhui, Yang, Jiale, Huang, Ruimin, Pan, Guoyu · 2021 · Figshare
- Developmental Characteristics of the Embryonic Liver Tissue and Long‐Term Culture of Primary Hepatocytes in DuckJie Wei, Jing Tang, Bo Zhang, Chenchen Du, Yunsheng Zhang, Ming Xie, Zhengkui Zhou, Shuisheng Hou · 2026 · Animal Research and One Health
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- A genome-wide gain-of-function screen identifies CDKN2C as HBV host factorCarla Eller · 2019 · theses.fr (ABES)
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- Precursor of chemically expanded hepatocytes (pre-cHep) with 1-million-fold expansion potential and liver repopulation capacityLinh Huynh, Yuichiro Higuchi, Cherie Tsz‐Yiu Law, Jakob Jeriha, Ines Battle, Rebecca Granskog, Shotaro Uehara, Fumihiko Kawamura, Victoria L. Gadd, Tak Yung Man et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Liver Tissue EngineeringKartik Mitra Venkat, Zhiyi Zhang, Kexiao Zheng, Vishnu Goutham Kota, Hwa Liang Leo, Lingyu Sun, Hanry Yu · 2026 · Elsevier eBooks
- Lentiviral SgRNA Delivery for CRISPR/Cas9 Editing in Cre-Dependent Cas9 Knock-in Primary Mouse HepatocytesLulu Zhang, Yi Zhang, Yijia Chi, Yong Ren, Qian Zhao, Dongxin Zhao · 2026 · Journal of Visualized Experiments
- A DPHV–liver module recapitulates AML infiltration and chemotherapy-induced hepatotoxicity with translational utilityBo Deng, Yue Ma, W Y Huang, Xiguang Xian, Yiyi Ding, Yifan Lu, Yi Yang, Wei Guo, Lina Mao, Xiaoli Wang et al. · 2026 · Science Advances
- Next-Generation Hepatocyte Expansion: Bridging Molecular Reprogramming with Multicellular Organoids for Clinical TranslationYiyang Zhou, Min Zeng, Gongbo Fu, Yi Gao · 2026 · Stem Cell Reviews and Reports
- Innovative models to explore hepatic involvement in Prader-Willi syndromeRomar Guintu Dabban, Graziano Grugni, Adele Bondesan, Benedetta Blarasin, Claudio Tiribelli, Cristina Bellarosa, Alessandro Sartorio · 2026 · Frontiers in Endocrinology
- Transient culture of adult human hepatocytes as organoids improves engineered liver engraftmentSarah H. Saxton, Inkyung Kang, Shannon Mitchell, Jeremy Lotto, A. Upadhyay, Chen-Hui Zou, C. Quirk, Tara N. McCray, Olivia Prado, Fredrik Johansson et al. · 2026 · Biomaterials
- Evaluating the translational feasibility and safety of IL-22 driven long-term hepatocyte expansionKatie Harrison, Jessica Nulty, Eirini Kyrana · 2026 · Journal of Hepatology
- Application of human liver cell models in drug development and toxicity studies: The role of membrane transportersEdit Szabó, Ágnes Telbisz, Zsuzsa Erdei, K Farkas, László Homolya, Balázs Sarkadi, Ágota Apáti · 2026 · Pharmacological Reviews
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