Multi-lineage human iPSC-derived platforms for disease modeling and drug discovery

Sharma, Arun, Sances, Samuel, Workman, Michael J., Svendsen, Clive N.·2020·Cell Stem Cell

Cites (266)

Items 201–265 of 265

  1. Astrocyte- neuron interaction as a mechanism responsible for generation of neural synchrony: a study based on modeling and experiments
    Amiri, Mahmood, Hosseinmardi, Narges, Bahrami, Fariba, Janahmadi, Mahyar · 2013 · Journal of Computational Neuroscience
  2. Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells
    Heemin Kang, Yu Ru V. Shih, Yongsung Hwang, Cai Wen, Vikram Rao, Timothy Seo, Shyni Varghese · 2014 · Acta Biomaterialia
  3. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    Yongchun Zhang, Ying Yang, Ming Zuo Jiang, Sarah X.L. Huang, Wanwei Zhang, Denise Al Alam, Soula Danopoulos, Munemasa Mori, Ya‐Wen Chen, Revathi Balasubramanian et al. · 2018 · Cell stem cell
  4. iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome
    Leigh Atchison, Nadia O. Abutaleb, Elizabeth Snyder-Mounts, Yantenew G. Gete, Alim Ladha, Thomas J. Ribar, Kan Cao, George A. Truskey · 2020 · Stem Cell Reports
  5. Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine
    Bradley W. Ellis, Aylin Acun, Uryan Isik Can, Pınar Zorlutuna · 2017 · Biomicrofluidics
  6. Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes
    Maria Demestre, Michael Orth, Karl J. Föhr, Kevin Achberger, Albert Christian Ludolph, Stefan Liebau, Tobias M. Boeckers · 2015 · Stem Cell Research
  7. Generating minicorneal organoids from human induced pluripotent stem cells
    Praveen Joseph Susaimanickam, Savitri Maddileti, Vinay Kumar, Sreedhar Rao Boyinpally, Ramavat Ravindar Naik, Milind N. Naik, G. Bhanuprakash Reddy, Veena Sangwan, Indumathi Mariappan · 2017 · Development
  8. Directed Differentiation of Human Induced Pluripotent Stem Cells Toward Bone and Cartilage: In Vitro Versus In Vivo Assays
    Matthew Phillips, Sergei A. Kuznetsov, Natasha Cherman, Kyeyoon Park, Kevin G. Chen, Britney N. McClendon, Rebecca S. Hamilton, Ronald D.G. McKay, Josh G. Chenoweth, Barbara S. Mallon et al. · 2014 · Stem Cells Translational Medicine
  9. Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
    Minjin Jeong, Molly O’Reilly, Nerissa K. Kirkwood, Jumana Yousuf Al-Aama, Majlinda Lako, Corné J. Kros, Lyle Armstrong · 2018 · Cell Death and Disease
  10. Drug-Induced Atrial Fibrillation
    Yaman Kaakeh, Brian R. Overholser, John C. Lopshire, James Edward Tisdale · 2012 · Drugs
  11. Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
    Ranran Zhang, Masaru Koido, Tomomi Tadokoro, Rie Ouchi, Tatsuya Matsuno, Yasuharu Ueno, Keisuke Sekine, Takanori Takebe, Hideki Taniguchi · 2018 · Stem Cell Reports
  12. Generating human antral and fundic gastric organoids from pluripotent stem cells
    Taylor R. Broda, K. McCracken, James M. Wells · 2018 · Nature Protocols
  13. Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology
    David E. Watson, Rosemarie Hunziker, John P. Wikswo · 2017 · Experimental Biology and Medicine
  14. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
    Ophelia K. Veraitch, Tetsuro Kobayashi, Yoichi Imaizumi, Wado Akamatsu, Takashi Sasaki, Shinya Yamanaka, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama · 2013 · Journal of Investigative Dermatology
  15. Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering
    Batchelder, Cynthia A., Martinez, Michele L., Tarantal, Alice F. · 2015 · PLOS ONE
  16. Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells
    Trott, Jamie, Tan, Ee Kim, Ong, Sheena, Titmarsh, Drew M., Denil, Simon L.I.J., Giam, Maybelline, Wong, Cheng Kit, Wang, Jiaxu, Shboul, Mohammad, Eio, Michelle et al. · 2017 · Stem Cell Reports
  17. Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells
    Patrick A. Schweizer, Fabrice F. Darche, Nina D. Ullrich, Pascal Geschwill, Boris Greber, Rasmus Rivinius, Claudia Seyler, Karin Müller‐Decker, Andreas Draguhn, Jochen Sven Utikal et al. · 2017 · Stem Cell Research & Therapy
  18. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium
    Nur Yucer, Marie Holzapfel, Tilley Jenkins Vogel, Lindsay Lenaeus, Loren Ornelas, Anna Ray Laury, Dhruv Sareen, Robert J. Barrett, Beth Y. Karlan, Clive N. Svendsen · 2017 · Scientific Reports
  19. CRISPR/Cas9‐Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells
    Arun Sharma, Christopher N. Toepfer, Tarsha L. Ward, Lauren K. Wasson, Radhika Agarwal, David A. Conner, Johnny H. Hu, Christine E. Seidman · 2018 · Current Protocols in Human Genetics
  20. Long-term flow through human intestinal organoids with the gut organoid flow chip (GOFlowChip)
    Barkan Sidar, Brittany R. Jenkins, Sha Huang, Jason R. Spence, Seth T. Walk, James N. Wilking · 2019 · Lab on a Chip
  21. Automatic Optimization of an in Silico Model of Human iPSC Derived Cardiomyocytes Recapitulating Calcium Handling Abnormalities
    Michelangelo Paci, Risto-Pekka Pölönen, Dario Cori, Kirsi Penttinen, Katriina Aalto‐Setälä, Stefano Severi, Jari Hyttinen · 2018 · Frontiers in Physiology
  22. Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
    Gi Bum Kim, David Rincon Fernandez Pacheco, David S. Saxon, Amy Yang, Sara Sabet, Marina Dutra‐Clarke, Rachelle Levy, Ashley Watkins, Hannah Park, Aslam Abbasi Akhtar et al. · 2019 · Cell
  23. Chondrogenic differentiation of human pluripotent stem cells in chondrocyte co-culture
    Chengjuan Qu, Katja A. Puttonen, Heli Lindeberg, Marika Ruponen, Outi Hovatta, Jari Koıstınaho, Mikko Juhani Lammi · 2013 · The International Journal of Biochemistry & Cell Biology
  24. Human induced pluripotent stem cell (hiPSC)-derived neurons respond to convulsant drugs when co-cultured with hiPSC-derived astrocytes
    Misawa Niki Ishii, Koji Yamamoto, Masanobu Shoji, Asano Asami, Yuji Kawamata · 2017 · Toxicology
  25. Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
    Ali Motazedian, Freya Bruveris, Santhosh V. R. Kumar, Jacqueline V. Schiesser, Tyrone Chen, Elizabeth Ng, Ann P. Chidgey, Christine Anne Wells, Andrew G. Elefanty, Edouard G. Stanley · 2020 · Nature Cell Biology
  26. Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor
    Yuting Tan, Lin Ye, Fei Xie, Ashley I. Beyer, Marcus O. Muench, Jiaming Wang, Chen Hui Zhu, Han Liu, Sai‐Juan Chen, Yuet Wai Kan · 2018 · Proceedings of the National Academy of Sciences
  27. Human induced pluripotent stem cell–derived lung progenitor and alveolar epithelial cells attenuate hyperoxia-induced lung injury
    Mehdi Shafa, Lavinia Ionescu, Arul Vadivel, Jennifer J.P. Collins, Liqun Xu, Shumei Zhong, Martin H. Kang, Genevieve de Caen, Manijeh Daneshmand, Jenny Shi et al. · 2017 · Cytotherapy
  28. PCL/PVA nanofibrous scaffold improve insulin-producing cells generation from human induced pluripotent stem cells
    Mohammad Foad Abazari, Fatemeh Soleimanifar, Maryam Nouri Aleagha, Sepehr Torabinejad, Navid Nasiri, Gholamreza Khamisipour, Javad Amini Mahabadi, Hossein Mahboudi, Seyed Ehsan Enderami, Ehsan Saburi et al. · 2018 · Gene
  29. Generation of insulin-producing cells from human induced pluripotent stem cells on PLLA/PVA nanofiber scaffold
    Seyed Ehsan Enderami, Mousa Kehtari, Mohammad Foad Abazari, Pegah Ghoraeian, Maryam Nouri Aleagha, Fatemeh Soleimanifar, Masoud Soleimani, Yousef Mortazavi, Samad Nadri, Hossein Mostafavi et al. · 2018 · Artificial Cells Nanomedicine and Biotechnology
  30. Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea
    Jianling Chen, Fanfan Hong, Cui Zhang, Liang Li, Cuicui Wang, Haosong Shi, Yong Fu, Jinfu Wang · 2018 · Stem Cell Research & Therapy
  31. Huntington’s Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support
    Veronica J. Garcia, David J. Rushton, Colton M. Tom, Nicholas D. Allen, Paul J. Kemp, Clive N. Svendsen, Virginia B. Mattis · 2019 · Frontiers in Neuroscience
  32. Human iPS Cell-Derived Insulin Producing Cells Form Vascularized Organoids under the Kidney Capsules of Diabetic Mice
    Sudhanshu P. Raikwar, Eun Mi Kim, William I. Sivitz, Chantal Allamargot, Daniel R. Thedens, Nicholas Zavazava · 2015 · PLoS ONE
  33. The NIH microphysiological systems program: developing in vitro tools for safety and efficacy in drug development
    Danilo A. Tagle · 2019 · Current Opinion in Pharmacology
  34. HiPSC-derived retinal ganglion cells grow dendritic arbors and functional axons on a tissue-engineered scaffold
    Kangjun Li, Xiufeng Zhong, Sijing Yang, Ziming Luo, Kang V. Li, Ying Liu, Song Cai, Huaiyu Gu, Shoutao Lu, Haijun Zhang et al. · 2017 · Acta Biomaterialia
  35. Culture of iPSCs Derived Pancreatic β-Like Cells In Vitro Using Decellularized Pancreatic Scaffolds: A Preliminary Trial
    Jian Wan, Yan Hong Huang, Pengcheng Zhou, Yibing Guo, Cen Wu, Shajun Zhu, Yao Wang, Lei Wang, Yuhua Lu, Zhiwei Wang · 2017 · BioMed Research International
  36. Bioengineered lungs generated from human i PSC s‐derived epithelial cells on native extracellular matrix
    Mahboobe Ghaedi, Andrew V. Le, Go Hatachi, Arkadi Beloiartsev, Kevin A. Rocco, Amogh Sivarapatna, Julio J. Mendez, Pavlina Baevova, Rachel Dyal, Katherine L. Leiby et al. · 2017 · Journal of Tissue Engineering and Regenerative Medicine
  37. Generation of Human iPSC–Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction
    Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Takanori Mori, Noriyuki Nakatsu, Kazuo Harada, Sumito Ito, Hiroshi Yamada et al. · 2019 · Cellular and Molecular Gastroenterology and Hepatology
  38. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
    Josowitz, Rebecca, Mulero-Navarro, Sonia, Rodriguez, Nelson A., Falce, Christine, Cohen, Ninette, Ullian, Erik M., Weiss, Lauren A., Rauen, Katherine A., Sobie, Eric A., Gelb, Bruce D. · 2016 · Stem Cell Reports
  39. Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System
    Cristiana Mattei, Rebecca Lim, Hannah R. Drury, Babak Nasr, Zihui Li, Melissa A. Tadros, Giovanna M. D’Abaco, Kathryn S. Stok, Bryony A. Nayagam, Mirella Dottori · 2019 · Frontiers in Cell and Developmental Biology
  40. Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
    Li‐Ping Liu, Yumei Li, Ningning Guo, Shu Li, Xiaolong Ma, Yixuan Zhang, Yimeng Gao, Jianling Huang, Dongxu Zheng, Lu-Yuan Wang et al. · 2019 · Cell Reports
  41. Elongation of Axon Extension for Human iPSC-Derived Retinal Ganglion Cells by a Nano-Imprinted Scaffold
    Tien‐Chun Yang, Jen-Hua Chuang, Waradee Buddhakosai, Wen-Ju Wu, Chen-Ju Lee, Wun-Syuan Chen, Yi-Ping Yang, Ming‐Chia Li, Chi‐Hsien Peng, Shih‐Jen Chen · 2017 · International Journal of Molecular Sciences
  42. Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas
    Hai-Ting Ma, K. Wert, D. Shvartsman, D. Melton, R. Jaenisch · 2018 · Proceedings of the National Academy of Sciences of the United States of America
  43. Humanized neuronal chimeric mouse brain generated by neonatally engrafted human iPSC-derived primitive neural progenitor cells
    Chen Chen, Woo-Yang Kim, Peng Jiang · 2016 · JCI Insight
  44. Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration
    Susumu Tajiri, Shuichiro Yamanaka, Toshinari Fujimoto, Kei Matsumoto, Atsuhiro Taguchi, Ryuichi Nishinakamura, Hirotaka James Okano, Takashi Yokoo · 2018 · Scientific Reports
  45. iPSC Bioprinting: Where are We at?
    Sara Romanazzo, Stephanie R. Nemec, Iman Roohani · 2019 · Materials
  46. Comparative characterization of decellularized renal scaffolds for tissue engineering
    Iris Fischer, Michael Westphal, Bella Rossbach, Nicole Bethke, Krithika Hariharan, Imran Ullah, Petra Reinke, Armin Kurtz, Harald Stachelscheid · 2017 · Biomedical Materials
  47. Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack
    Jorge Luis Espinoza, Mahmoud El‐Badry, Kazuhisa Chonabayashi, Yoshinori Yoshida, Takamasa Katagiri, Kenichi Harada, Noriharu Nakagawa, Yoshitaka Zaimoku, Tatsuya Imi, Hiroyuki Takamatsu et al. · 2018 · Blood Advances
  48. Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice
    Corinne Haller, Julie Piccand, F. De Franceschi, Y. Ohi, Anindita Bhoumik, C. Boss, U. de Marchi, Guillaume E. Jacot, S. Métairon, P. Descombes et al. · 2019 · Stem Cell Reports
  49. Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium
    Allison E. Songstad, Kristan S. Worthington, Kathleen R. Chirco, Joseph C. Giacalone, S. Scott Whitmore, Kristin R. Anfinson, Dalyz Ochoa, Cathryn M. Cranston, Megan J. Riker, Maurine Neiman et al. · 2017 · Stem Cells Translational Medicine
  50. Micro vapor bubble jet flow for safe and high-rate fluorescence-activated cell sorting
    Koen de Wijs, Chengxun Liu, Alexandra Dusa, Dries Vercruysse, Bivragh Majeed, Deniz Sabuncuoglu Tezcan, Kamil Blaszkiewicz, Josine Loo, Liesbet Lagae · 2017 · Lab on a Chip
  51. Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co‐express gamma and beta globins
    Cheng‐Tao Yang, Anna French, Pollyanna Agnes Goh, Alistair T. Pagnamenta, Sachith Mettananda, Jenny C. Taylor, Samantha J.L. Knight, Amit Chunilal Nathwani, David J. Roberts, Suzanne M. Watt et al. · 2014 · British Journal of Haematology
  52. Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery
    Valentina Benedetti, Valerio Brizi, Patrizia Guida, Susanna Tomasoni, Osele Ciampi, Elena Angeli, U. Valbusa, Ariela Benigni, Giuseppe Remuzzi, Christodoulos Xinaris · 2018 · EBioMedicine
  53. In vitro and in vivo imaging and tracking of intestinal organoids from human induced pluripotent stem cells
    Kwang Bo Jung, Hana Lee, Ye Seul Son, Ji Hye Lee, Hyun‐Soo Cho, Mi‐Ok Lee, Jung‐Hwa Oh, Jaemin Lee, Seokho Kim, Cho‐Rok Jung et al. · 2017 · The FASEB Journal
  54. Lift NIH restrictions on chimera research
    Arun Sharma, Vittorio Sebastiano, Christopher Thomas Scott, David Christopher Magnus, Naoko Koyano‐Nakagawa, Daniel J. Garry, Owen N. Witte, Hiromitsu Nakauchi, Joseph C. Wu, Irving L. Weissman et al. · 2015 · Science
  55. Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease
    John N. Mariani, Lisa Zou, Steven A. Goldman · 2019 · Methods in molecular biology
  56. Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
    Yena Kim, Ji Hyeon Ju · 2019 · Journal of Visualized Experiments
  57. Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice
    Hiroki Takeda, Makoto Hosoya, Masato Fujioka, Chika Saegusa, Tsubasa Saeki, Toru Miwa, Hideyuki Okano, Ryosei Minoda · 2018 · Scientific Reports
  58. Pancreatic differentiation of induced pluripotent stem cells in activin A-grafted gelatin-poly(lactide-co-glycolide) nanoparticle scaffolds with induction of LY294002 and retinoic acid
    Yung‐Chih Kuo, Yu‐Chuan Liu, Rajendiran Rajesh · 2017 · Materials Science and Engineering C
  59. Co-culture of human induced pluripotent stem cell-derived retinal pigment epithelial cells and endothelial cells on double collagen-coated honeycomb films
    Maria Teresa Calejo, Jaakko Saari, Hanna Vuorenpää, Elina Vuorimaa, Pasi J. Kallio, Katriina Aalto‐Setälä, Susanna Miettinen, Heli Skottman, Minna Kellomäki, Kati Juuti‐Uusitalo · 2019 · Acta Biomaterialia
  60. Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell‐Derived Neurons In Vitro
    Niliksha Gunewardene, Duncan E. Crombie, Mirella Dottori, Bryony A. Nayagam · 2016 · Stem Cells International
  61. Effects of Co-Culture Media on Hepatic Differentiation of hiPSC with or without HUVEC Co-Culture
    Nora Freyer, Selina Greuel, Fanny Knöspel, Nadja Strahl, Leila Amini, Frank Jacobs, Mario Monshouwer, Katrin Zeilinger · 2017 · International Journal of Molecular Sciences
  62. Establishment of a Human Blood‐Brain Barrier Co‐Culture Model Mimicking the Neurovascular Unit Using Induced Pluripotent Stem Cells
    Antje Appelt‐Menzel, Alevtina Cubukova, Marco Metzger · 2018 · Current Protocols in Stem Cell Biology
  63. Characterization of Neurodevelopmental Abnormalities in iPSC-Derived Striatal Cultures from Patients with Huntington’s Disease
    Pranav P. Mathkar, Divya Suresh, James Dunn, Colton M. Tom, Virginia B. Mattis · 2019 · Journal of Huntington s Disease
  64. TCM visualizes trajectories and cell populations from single cell data
    Wuming Gong, Il‐Youp Kwak, Naoko Koyano‐Nakagawa, Wei Pan, Daniel J. Garry · 2018 · Nature Communications
  65. A Co-culture Model for Determining the Target Specificity of the de novo Generated Retinal Ganglion Cells
    Pooja Teotia, Matthew J. Van Hook, Iqbal Ahmad · 2017 · BIO-PROTOCOL