Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: Preliminary results in Asian patients
Song, Won Kyung, Park, Kyung-Mi, Kim, Hyun-Ju, Lee, Jae Ho, Choi, Jinjung, Chong, So Young, Shim, Sung Han, Del Priore, Lucian V. +1 more·2015·Stem Cell Reports
Cited by (393)
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- Stem Cell Therapies for Intraocular Disease.Prabakar Kumar Rao · 2022 · PubMed Central
- Identification of age-associated proteins and functional alterations in human primary retinal pigment epithelium cellsXiuxiu Jin, Jingyang Liu, Weiping Wang, Jiangfeng Li, Guangming Liu, Ruiqi Qiu, Mingzhu Yang, Meng Liu, Lin Yang, Xiaofeng Du et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
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- Characterization of Bruch's Membrane Formation in Human Fetal Retina and De Novo Membrane Synthesis by hPSC-Derived Retinal Pigment EpitheliumEmily P. Lanning, Matthew James Branch, Philippa Harding, Miriam Margari, Alexander J. Smith, Robin R. Ali, Rachael A. Pearson · 2025 · Investigative Ophthalmology & Visual Science
- Visual Neurorestoration: An Expert Review of Current Strategies for Restoring Vision in HumansJonathon Cavaleri, Michelle P. Lin, Kevin Wu, Zachary D. Gilbert, Connie Y. Huang, Yu Tung Lo, Vahini Garimella, Jonathan Dallas, Robert Grady Briggs, Austin J. Borja et al. · 2025 · Brain Sciences
- Postmortem Retinal Structural and Metabolic Analysis After Human Embryonic Stem Cell–Derived Retinal Pigment Epithelium Transplantation in a Patient With Stargardt DiseaseNiranjana Kesavamoorthy, Maria Sibug Saber, Erin H. Su, Jason A. Junge, Narsing A. Rao, Hossein Ameri · 2025 · Journal of VitreoRetinal Diseases
- Advances in retinal pigment epithelium transplantation for age-related macular degeneration: bridging biology to therapeutic frontiersMayuri Bhargava, Karishma N. Mehta, Bhav Harshad Parikh, Zengping Liu, Xinyi Su · 2026 · Stem Cell Research & Therapy
- Methods for Growing Retinal Pigment Epithelial Cells: Current Protocols and Future RecommendationsAaron Fronk · 2021 · Digital Commons - USU (Utah State University)
- Latest Developments in the Field of Stem Cell Research and Regenerative Medicine Compiled from Publicly Available Information and Press Releases from Nonacademic Institutions 1 April–31 May 2017Duško Ilić, Sharon Yau · 2017 · Regenerative Medicine
- Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation DisordersKamal Uddin Zaidi · 2017 · Journal of Stem Cell Research & Therapeutics
- A New Wnt1-CRE Tomato Rosa Embryonic Stem Cell Line: A Tool for Studying Neural Crest Cell Integration CapacitySoledad Acuna‐Mendoza, Sabrina Martín, Sabine Kuchler‐Bopp, Sandy Ribes, Jérémy H. Thalgott, Catherine Chaussain, Sophie Creuzet, Hervé Lesot, Franck Lebrin, Anne Poliard · 2017 · Stem Cells and Development
- Pluripotent Stem Cell BanksBegoña Arán, Ángel Raya, Anna Veiga · 2018 · Springer eBooks
- Biomimetic Approaches for Targeted Nanomedicine: Current Status and Future PerspectivesJaya Agnihotri, Priyanka Maurya, Shobhna Singh, Shubhini Awasthi Saraf · 2018 · Current Drug Therapy
- Photoreceptor Cell Replacement Therapy from Stem CellsGilbert Bernier · 2018 · Fundamental biomedical technologies
- Retinal repair in tissue engineering perspectivesDeepthi S. Rajendran Nair, Biju B. Thomas · 2022 · Elsevier eBooks
- Stem Cells Application in Eye Regeneration and Restoration of VisionRanjeet Singh Mahla, Ananda Kishore Mukherjee, Sakina Amin, Ashwin Jainarayanan, Nithishwer Mouroug Anand, Ashwin M. Nandakumar, Abhinandan Deva Prasad · 2023 · Springer eBooks
- Stem Cell Therapy and Retinal RegenerationNikhlesh Kumar Singh · 2024 · Elsevier eBooks
- Stem Cells Application in Eye Regeneration and Restoration of VisionRanjeet Singh Mahla, Ananda Kishore Mukherjee, Sakina Amin, Ashwin Jainarayanan, Nithishwer Mouroug Anand, Ashwin M. Nandakumar, Abhinandan Deva Prasad · 2024 · Springer eBooks
- Stem cells and their applications in repairing the damaged nervous systemStephanie Michelle Willerth · 2017 · Elsevier eBooks
- Mechanisms and Clinical Applications of Stem Cell TherapyMuhibullah S. Tora, Kelly M. Poth, Nathan Hardcastle, Kaitlin P. Sandor, Casey Anthony, Long Di, Nicholas M. Boulis · 2019 · Elsevier eBooks
- In vitro differentiation of cGMP-grade retinal pigmented epithelium from human embryonic stem cellsFernando Henrique Lojudice, Rodrigo Brant, Francesco Innocenti, Carlos Eduardo da Silveira Franciozi, Priscila Cardoso Cristovam, Maurício Maia, Mari Cleide Sogayar, Rubens Belfort · 2019 · International Journal of Retina and Vitreous
- Point-of-Care Nanoplatforms for Glaucoma and Age-Related Macular Degeneration: Clinical Implications and Emerging ConceptsHoney Goel, Richu Singla, Ashok K. Tiwary · 2020 · Springer eBooks
- Types and Origin of Stem CellsLucíola S. Barcelos, Pollyana Ribeiro Castro, Elisabeth Tamara Strässler, Nicolle Kränkel · 2020 · Springer eBooks
- New Drugs in the Pipeline for the Management of AMDAna Ambrósio Marta, Bernardete Pessoa · 2021 · IntechOpen eBooks
- Nanoparticles as Cell Tracking Agents in Human Ocular Cell Transplantation TherapyDavid C Mundy, Jeffrey Louis Goldberg · 2021 · Current Ophthalmology Reports
- Trial Interventions in ABCA4- RetinopathyMajid Al Breiki · 2020
- Molecular profiling of retinal pigment epithelial cell differentiation for therapeutic useSandra Petrus-Reurer, Alex R. Lederer, Laura Baqué-Vidal, Iyadh Douagi, Belinda Pannagel, Monica Aronsson, Hammurabi Bartuma, Magdalena Wagner, Helder André, Erik Sundström et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Mitos y realidades del uso de las células troncales en la terapia oftalmológicaRosario Gulías-Cañizo, Federico Castro‐Muñozledo · 2016 · Revista Mexicana de Oftalmología
- Stem cells pass safety test in vision-loss trialHeidi K. Ledford · 2015 · Nature
- Human Embryonic Stem Cell Research vs. Alternative Stem Cell Research: Is there a compromise?Halle Herringshaw · 2016 · Carroll Collected (John Carroll University)
- Répartie à propos de l’article de Philippe LysyLaure Coulombel · 2016 · médecine/sciences
- ŠTARGARDTO GELTONOSIOS DĖMĖS DISTROFIJOS SKIRTINGOS FENOTIPINĖS IŠRAIŠKOSRasa Liutkevičienė, Brigita Glebauskienė, Virginija Ašmonienė, Arvydas Gelžinis, Loresa Kriaučiūnienė, Renata Vaičiulienė, Jurgis Trumpaitis, Reda Žemaitienė · 2016 · Medicinos teorija ir praktika
- Recent Innovations in Stem Cell Therapy for Retinal DiseaseAdnan Mallick, Ronni M. Lieberman · 2016 · Advances in Ophthalmology and Optometry
- Stem Cell Trials for Retinal Disease: An UpdateHenry J. Klassen · 2017 · Stem cells in clinical applications
- Stem Cell Therapy for Retinal Disease Treatment: An UpdateVamsi K. Gullapalli, Marco A. Zarbin · 2017 · Stem cells in clinical applications
- A Revised Hemodynamic Theory of Age-RelatedBradley D. Gelfand, Jayakrishna Ambati · 2016
- A systemically-delivered stem cell therapy for dry age related macular degenerationS. Louise Pay · 2017 · IUScholarWorks (Indiana University)
- Tecnologias celulares avançadas: desafios biotecnológicos e regulatóriosJosé Mauro Granjeiro, Isabella Fernandes Delgado, Norma Labarthe · 2018 · Vigilância Sanitária em Debate
- Hope or Hype: Stem Cells as Therapeutics in Retinal Degenerative DiseasesSowmya Parameswaran · 2018 · Springer eBooks
- Stem cell therapy and regenerative medicine in RPE degenerative disease: advances and challengesJulia Thiemi Takiuti, Vítor K. L. Takahashi, Mary Ben L. Apatoff, Stephen H. Tsang · 2018 · Expert Review of Ophthalmology
- Manufacturing of human mesenchymal stem cells: the analytical challengesEmma C. Neale-Edwards · 2018 · Loughborough University Institutional Repository (Loughborough University)
- Biofabrication of choroid-retina tissue construct for modelling of age-related macular degeneration diseaseEdgar Yong Sheng Tan · 2019
- Differentiation and Maturation Effect of All-trans Retinoic Acid on Cultured Fetal RPE and Stem Cell-Derived RPE Cells for Cell-Based TherapyTingyu Yan, Na Yang, Wei Hu, Xinxin Zhang, Xuedong Li, Youjin Wang, Jun Kong · 2021
- Induced pluripotent stem cells for treatment of heart failureShigeru Miyagawa, Yoshiki Sawa · 2021 · Elsevier eBooks
- Stem cells in degenerative retinal diseasesAli Devebacak · 2021 · European eye research
- Stem Cells: An Emerging Field for MedicineAlison Kraft, Frank Barry · 2017 · Royal Society of Chemistry eBooks
- Biological aspects of security cell culture in vitroI. N. Lyapun · 2021 · Molecular Genetics Microbiology and Virology (Russian)
- Development of a 48-Well Dynamic Suspension Culture System for Pancreatic Differentiation from Human Embryonic Stem CellsYizhe Song, Xiaoqian Chen, Decan Liang, Jing Liu, Jingqiu Li, Zhensheng Ou, Tingting Tang, Peiwen Xing, Leilei Guo, Shidu Zhang et al. · 2021 · Stem Cell Reviews and Reports
- Biological Aspects of Cell Culture Security In VitroI. N. Lyapun · 2021 · Molecular Genetics Microbiology and Virology
- 固相萃取-高效液相色谱-荧光检测法测定海水中的多环芳烃李先国, 阎国芳, 周晓, 虢新运, 王岩, 刘金燕 · 2009
- Stem Cell Therapies for Cardiac Disease: Which Cell Types Are the BestJiaqi Wen · 2021 · International Conference on Bioinformatics and Biomedical Science (ICBBS)
- HUMAN EMBRYONIC STEM CELL DERIVATIVE SUBRETINAL PIGMENT EPITHELIAL TRANSPLANTATION AS A TREATMENT FOR DRY-TYPE MACULARMuhammad Thifan Satyagraha, Andhwika Afif Fahrezi, Rafi Annisa Ulum, Gibran Chandra Syarif Hidayatullah · 2022 · JIMKI Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
- Advanced Therapy Medicinal Products for Eye Diseases: Goals and ChallengesYolanda Diebold, Laura García-Posadas · 2021 · MDPI eBooks
- Faculty Opinions recommendation of Ethical and Safety Issues of Stem Cell-Based Therapy.Neal L. Millar · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Differentiation and Maturation Effect of All-trans Retinoic Acid on Cultured Fetal RPE and Stem Cell-Derived RPE Cells for Cell-Based TherapyTingyu Yan, Na Yang, Wei Hu, Xinxin Zhang, Xuedong Li, Youjin Wang, Jun Kong · 2020 · Research Square
- Retinal degenerationErin A. Kimbrel, Robert Lanza · 2020 · Elsevier eBooks
- Clinical Trials of Stem Cell Therapies Using Biomaterials2019 · Royal Society of Chemistry eBooks
- Latest Developments in the Field of Stem cell Research and Regenerative Medicine Compiled from Publicly Available Information and Press Releases from Nonacademic Institutions 1 April–31 May 2015Duško Ilić · 2015 · Regenerative Medicine
- Bibliography2018 · Elsevier eBooks
- The Potential of Stem Cells in Ocular TreatmentsS. Amer Riazuddin, Shahid Y. Khan, Muhammad Ali · 2022 · Springer eBooks
- Different Applications of Stem Cells Therapy for Degenerative Retinal DiseasesAntonio Florido, Mauro Budini, Filippo Avogaro, Enzo Maria Vingolo · 2022 · Journal of Translational Medicine & Transplantation Research
- Stem cell-based organoid cultures as innovative approaches for ocular repair and regenerationIgor O. Nasonkin, Lawrence J. Rizzolo · 2023 · Elsevier eBooks
- Human stem cell-derived retinal pigment epithelial cells for retinal regeneration: differentiation and clinical translationHang Zhang, Zi‐Bing Jin · 2023 · Elsevier eBooks
- Analysis of the results of transplantation of the retinal pigment epithelium in the experimentMaria A. Lagarkova, Л. А. Катаргина, Natalya S. Izmailova, Pavel Andreevich Ilyukhin, A. E. Kharitonov, O. A. Utkina, N. V. Neroeva · 2023 · Genes and Cells
- Current design and advances of hydrogel for retinal tissue engineering and regenerative medicineJoo Hee Choi, Normin-Erdene Tumursukh, Wooyoup Kim, Jin-Sol Seo, Sooin Kim, Se Eun Kim, Jeong Eun Song, Gilson Khang · 2023 · Elsevier eBooks
- Generating Retinas through Guided Pluripotent Stem Cell Differentiation and Direct Somatic Cell ReprogrammingKe Kurt Zhang, Wenwen Cai, Leyi Hu, Shuyi Chen · 2023 · Current Stem Cell Research & Therapy
- Immune rejection: current understanding and new solutionsHanlu Chen · 2023 · Highlights in Science Engineering and Technology
- Introduction to Age-Related Macular DegenerationJeffrey Neill Weiss · 2024 · Springer eBooks
- Atrophic Macular Degeneration and Stem Cell Therapy: A Clinical ReviewSilvia Babighian, Maria Sole Zanella, Irene Gattazzo, Alessandro Galan, Caterina Gagliano, Fabiana D’Esposito, Marco Zeppieri · 2024 · Advances in experimental medicine and biology
- Mechanisms and Challenges of Stem Cell-Mediated NeuroregenerationAbraham Jacob Al-Ahmad · 2025 · Springer eBooks
- The Programme for Manufacture of hPSC‑Based Products for AMD and PDLei Wang, Yukai Wang, Da Li, Juan Ma, Yun Wei Sun, Xia Li, Haiying Wang, Shuaishuai Niu, Glyn Nigel Stacey, Tongbiao Zhao et al. · 2025 · Advances in experimental medicine and biology
- Long‐term predictive outcomes of stem cell therapy for degenerative retinal diseasesHai‐Long He, Xuan‐Yu Chen, Ming‐Xia Du, Yi‐Hui Li, Yi‐Han Wang, Zi‐Bing Jin · 2025 · Eye & ENT Research
- Additional file 1 of Cell therapy for retinal degenerative disorders: a systematic review and three-level meta-analysisAlireza Soltani Khaboushan, Ebadpour, Negar, Mohammad Mehdi Johari Moghadam, Zahra Rezaee, A.M. Kajbafzadeh, Masoumeh Majidi Zolbin · 2024 · Figshare
- Additional file 1 of Ex vivo cultivated retinal pigment epithelial cell transplantation for the treatment of rabbit corneal endothelial dysfunctionChunxiao Dong, Dulei Zou, Duan, Haoyun, Xiangyue Hu, Zhou, Qingjun, 史伟云, Li, Zongyi · 2023 · Figshare
- Additional file 1 of Changes in best-corrected visual acuity in patients with dry age-related macular degeneration after stem cell transplantation: systematic review and meta-analysisLi, Licheng, Yu, Yang, Lin, Shu, Hu, Jianmin · 2022 · Figshare
- Additional file 1 of Improving cell survival and engraftment in vivo via layer-by-layer nanocoating of hESC-derived RPE cellsLiyan Ru, Nan Wu, Wei, Keyu, Yuxiao Zeng, Li, Qiyou, Weng, Chuanhuang, Chunge Ren, Bangqi Ren, Huo, Da, Li, Yijian et al. · 2020 · Figshare
- Additional file 2 of Cell therapy for retinal degenerative disorders: a systematic review and three-level meta-analysisAlireza Soltani Khaboushan, Ebadpour, Negar, Mohammad Mehdi Johari Moghadam, Zahra Rezaee, A.M. Kajbafzadeh, Masoumeh Majidi Zolbin · 2024 · Figshare
- Additional file 2 of Ex vivo cultivated retinal pigment epithelial cell transplantation for the treatment of rabbit corneal endothelial dysfunctionChunxiao Dong, Dulei Zou, Duan, Haoyun, Xiangyue Hu, Zhou, Qingjun, 史伟云, Li, Zongyi · 2023 · Figshare
- Generation of a three-dimensional retinal-like structure using a laminin-111-modified alginate layerSamaneh Najafian, Mohammad Hossein Nasr Esfahani, Amirreza Haghighatnejad, Fereshteh Karamali · 2026 · Journal of Biomaterials Applications
- Développement d'un modèle cellulaire de la DMLA à partir de cellules de patients pour étudier la physiopathologie de la maladieAudrey Voisin · 2017 · theses.fr (ABES)
- Automatisation de la différenciation des cellules souches pluripotentes humaines en cellules de l’épithélium pigmentaire rétinien et modélisation des symptômes rétiniens associés à la mutation d’APCFlorian Régent · 2018
- Stargardt's Macular Dystrophy different phenotipical aspectsRasa Liutkevičienė, Brigita Glebauskienė, Virginija Ašmonienė, Arvydas Gelžinis, Loresa Kriaučiūnienė, Renata Vaičiulienė, Jurgis Trumpaitis, Reda Žemaitienė · 2015 · Lithuanian University of Health Sciences
- Free-standing chondroitin sulfate/collagen multilayered films as preliminary Bruch's membrane-mimetic platform for retinal pigment epithelial cell cultureLan Duo, Pengfei Cheng, Wenpei Jiang, Quankui Lin · 2026 · International Journal of Biological Macromolecules
- Direct Chemical Reprogramming of Human Fibroblasts into Retinal Progenitor-like Cells for Ocular DeliveryYueh-Chang Lee, Pei‐Lun Lai, Chien-Ying Lai, Fang-Ling Chang, Shang-Yen Wu, Po-Yu Lin, Chi‐Hsuan Chuang, Yu-Xin Chou, Z Chen, Yu-Cheng Wu et al. · 2026 · Journal of Functional Biomaterials
- Stem cells and pyroptosis in retinal injurySrijit Das, Halima AlBalushi · 2026 · Elsevier eBooks
- Update on the Management of ABCA4 Retinopathy (Stargardt Disease)Deepika C. Parameswarappa, Dhanashree Ratra, Goura Chattannavar, Srikanta Kumar Padhy · 2026 · Ophthalmology and Therapy
- Incorporation of low-oxidation graphene oxide into electrospun poly(ε-caprolactone) /gelatin scaffolds for human embryonic stem cell‐derived retinal pigment epithelium cell transplantationWei Wu, Yujia Cao, Qi Li, Shuyun Hu, Daniel Soo Lin Wong, Veluchamy A. Barathi, Lingam Gopal, Liqiang Wang, Jiajia Xue, Zengping Liu · 2026 · Biomaterials
- Stem Cell Therapy for Inherited Retinal Disorders: Rebuilding the RetinaAnupam Garg, Ishrat Ahmed · 2026 · American Journal of Ophthalmology
- A retinal pigment epithelium cell therapy for age-related macular degeneration: Current challenges and future directionsAudra M. A. Shadforth, Damien G. Harkin · 2026 · Elsevier eBooks
- The Biology and Cell Engineering of Retinal Pigment Epithelium Cell Transplantation: Developing a Living DrugSudipta Mahato, Elena Daniele, Colby F. Lewallen, Ruchi Sharma, Kapil Bharti · 2026 · Annual Review of Vision Science
- Stem Cell‐Based Strategies for Retinal Cell RestorationBehzad Safarpour Lima, Shima Sayanjali, Nir Shoham-Hazon · 2026 · Biotechnology Journal