Expanding the PP2A Interactome by Defining a B56-Specific SLiM
Wang, Xinru, Bajaj, Rakhi, Bollen, Mathieu, Peti, Wolfgang, Page, Rebecca·2016·Structure
Cited by (149)
Items 101–149 of 149
- Pathogenic PPP2R5D variants disrupt neuronal development and neurite outgrowth in patient-derived neurons that are reversed by allele-specific knockdownRandee E. Young, Michael V. Zuccaro, Charles A. LeDuc, Noélle D. Germain, Tae Hyun Kim, Patrick D. Sarmiere, Wendy K. Chung · 2025 · Human Genetics and Genomics Advances
- Decoding the language of PLK1 docking motifs and activation mechanismsArianna Esposito-Verza, Andrea Musacchio, Duccio Conti · 2025 · Trends in Cell Biology
- The phospho-dependent role of BRCA2 on the maintenance of chromosome integrityÅsa Ehlén, Gaetana Sessa, Sophie Zinn‐Justin, Aura Carreira · 2021 · Cell Cycle
- A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochoresLindsey A Allan, Andrea Corno, Juan Manuel Valverde, Rachel L. Toth, Tony Ly, Adrian Thomas Saurin · 2025 · Nature Communications
- PP2ARts1 antagonizes Rck2-mediated hyperosmotic stress signaling in yeastDavid Maria Hollenstein, Jiri Veis, Natalie Romanov, Gabriela Gérecová, Egon Ogris, Markus Hartl, Gustav Ammerer, Wolfgang Reiter · 2022 · Microbiological Research
- Biochemistry and Protein Interactions of the CYREN MicroproteinLina Xie, Marianne E. Bowman, Gordon V. Louie, Cheng Zhang, Maziar S. Ardejani, Xuemei Huang, Qian Chu, Cynthia J. Donaldson, Joan M. Vaughan, Huanqi Shan et al. · 2023 · Biochemistry
- Fuzziness in enzymatic catalysisSachin S. Katti, Tvesha Parikh, Rachel J. Godek, Rebecca Page, Wolfgang Peti · 2025 · Current Opinion in Structural Biology
- The phosphatase activity of the PPP2R5D-PP2A holoenzyme modulates liprin-α1 liquid-liquid phase separationAbigail Mayer, Rita Derua, Elijah Spahn, Iris Verbinnen, Yang Zhang, Michelle Guzman, Mark R. Swingle, Brian E. Wadzinski, Richard E. Honkanen, Veerle Janssens et al. · 2025 · Journal of Biological Chemistry
- Evolutionary Conservation of PP2A Antagonism and G2/M Cell Cycle Arrest in Maedi-Visna Virus VifAdeline M. Luperchio, S. Jönsson, Daniel J. Salamango · 2022 · Viruses
- The N‐terminal intrinsically disordered region of Ncb5or docks with the cytochrome b 5 core to form a helical motif that is of ancient originDavid R. Benson, Bin Deng, Maithri M. Kashipathy, S. Lovell, K.P. Battaile, Anne Cooper, Philip Gao, Aron W. Fenton, Hao Zhu · 2023 · Proteins Structure Function and Bioinformatics
- Houge-Janssens syndromeGunnar Houge, Sofia Douzgou, Tzung‐Chien Hsieh, Iris Verbinnen, Veerle Janssens · 2025 · European Journal of Human Genetics
- Lnc(ing) interferon production and actionGanes C. Sen, Bryan R.G. Williams · 2019 · Cell Research
- FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55⍺/PP2A phosphataseJason S. Wasserman, Bulat Faezov, Kishan R. Patel, Alison Kurimchak, Seren M. Palacio, Holly A. Fowle, Brennan C McEwan, Qifang Xu, Ziran Zhao, Lauren E. Cressey et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- PP2A-B56 regulates Mid1 protein levels for proper cytokinesis in fission yeastMadeline L. Chrupcala, James B. Moseley · 2025 · Molecular Biology of the Cell
- PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progressionJimena Druker, Hao Jiang, Dilem Shakir, Fraser Child, Vanesa Álvarez, Melpomeni Platani, Andrea Corno, Constance Alabert, Adrian Thomas Saurin, Jason R. Swedlow et al. · 2026 · eLife
- Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitorShasha Shi, Xueni Li, Christopher Alderman, Lars Wick, Wei Huang, North Foulon, Lingdi Zhang, John J. Rossi, Wenxin Hu, Shouqing Cui et al. · 2025 · Journal of Biological Chemistry
- The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b5 core to form a helical motif that is of ancient originHao Zhu, David R. Benson, Bin Deng, Maithri M. Kashipathy, S. Lovell, K.P. Battaile, Anne Cooper, Philip Gao, Aron W. Fenton · 2023
- Single-cell delineation of strain-specific HIV-1 Vif activities using dual reporter sensor cells and live cell imagingJorge F. Guerrero, Laraine L. Zimdars, James W. Bruce, Jordan T. Becker, Edward L. Evans, Soroosh Torabi, Rob Striker, Scott Michael Berry, Nathan M. Sherer · 2025 · Journal of Virology
- Combination of in vivo and in vitro phosphoproteomics determines the PP2A target repertoire on proteome scaleMelanie Brunner, Zehan Hu, Heidy Elkhaligy, Gloria Lampo, Carole Roubaty, Christine Vionnet, Devanarayanan Siva Sankar, Sean J. McIlwain, Stephanie Kaeser-Pebernard, Yongna Xing et al. · 2025 · Cell Reports Methods
- Dual-site phosphorylation of SLX4 stabilizes the SLX4–MUS81 interface to promote mitotic SMX assembly and genome protectionBrandon J. Payliss, Hwa Young Yun, Sarina Doshi, Alexander S. Lemak, Ying Wah Elizabeth Tse, Camila M. Aprosoff, Scott Houliston, C.H. Arrowsmith, Haley D.M. Wyatt · 2026 · Nucleic Acids Research
- Positive selection analysis highlights key positions in plant PP2A regulatory subunitsMatthew Aaron Booker, Alison DeLong · 2017 · Plant Signaling & Behavior
- On the Regulation of Mitosis by the Kinetochore, a Macromolecular Complex and Organising Hub of Eukaryotic OrganismsVíctor M. Bolaños-García · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
- Use of Mitotic Protein Kinase Inhibitors and Phospho-Specific Antibodies to Monitor Protein Phosphorylation During the Cell CycleIsha Nasa, Greg B. G. Moorhead, Arminja Nadine Kettenbach · 2021 · Methods in molecular biology
- BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytesLaura Bel Borja, Flavie Soubigou, Samuel J.P. Taylor, Conchita Fraguas Bringas, Jacqueline Budrewicz, Pablo Lara-González, Christopher G. Sorensen Turpin, Joshua N. Bembenek, Dhanya K. Cheerambathur, Federico Pelisch · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeastGalal Yahya, Yehui Wu, Karolina Peplowska, Jennifer M. Röhrl, Young‐Min Soh, Frank Bürmann, Stephan Gruber, Zuzana Štorchová · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firingFiona Jenkinson, Kang Wei Tan, Barbara Schöpf, Miguel Santos, Ivan Phanada, Philip Zegerman · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A PP4 foszfatáz kölcsönható partnereinek azonosítása és szubsztrátum-felismerő mechanizmusának feltárásaZoltán Kármán · 2021
- Faculty Opinions recommendation of Proteome-wide analysis of phospho-regulated PDZ domain interactions.M Madan Babu, Xiaohan Li · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.Hiroyuki Yamano, Meghna Kataria · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Fam72a is a Novel Cell-Cycle-Regulated Gene that Supports Proliferation and Antagonizes Apoptosis Through Reprogramming PP2A SubstratesYuan Fu, Xiaofan Jia, Jinwei Yuan, Qiujing Yu, Ting Wang · 2022 · SSRN Electronic Journal
- Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzymeCheng-Guo Wu, Vijaya Kumar Balakrishnan, Pankaj Singh Parihar, Kirill Konovolov, Yu‐Chia Chen, Ronald A. Merrill, Hui Alex Wei, Bridget O Carragher, Ramya Sundaresan, Qiang Cui et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- A PP4 foszfatáz és a Centrobin kapcsolata a DNS hibajavítás késői szakaszaibanZsuzsánna Réthi‐Nagy · 2023
- Potential Involvement of Protein Phosphatase PPP2CA on Protein Synthesis and Cell Cycle During SARS-CoV-2 Infection: A Meta-Analysis InvestigationLuca Paulino Otvos, Giulia I. M. Garrito, Gabriel Ernesto Jara, Paulo Sérgio Lopes de Oliveira, Luciana E. S. F. Machado · 2025 · Kinases and Phosphatases
- PP2A-B56α is a key determinant of cardiac protein phosphorylation and functional responses to β-adrenergic signallingAlican Güran, Yanlong Ji, Pan Fang, Kuan‐Ting Pan, Henning Urlaub, Metin Avkiran, Christof Lenz, Kate L. Weeks · 2025 · Journal of Molecular and Cellular Cardiology Plus
- Ultrasensitive bioluminescent reporters of protein kinase A based on luciferase activity modulated by phosphorylation (PKA LAMP)Yufang Kong, Stefan Strack · 2025 · Journal of Biological Chemistry
- PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progressionJimena Druker, Hao Jiang, Dilem Shakir, Fraser Child, Vanesa Álvarez, Melpomeni Platani, Andrea Corno, Constance Alabert, Adrian Thomas Saurin, Jason R. Swedlow et al. · 2025 · eLife
- PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progressionJimena Druker, Hao Jiang, Dilem Shakir, Fraser Child, Vanesa Álvarez, Melpomeni Platani, Andrea Corno, Constance Alabert, Adrian Thomas Saurin, Jason R. Swedlow et al. · 2025 · eLife
- Structural and biochemical studies of human PP2A(B55) holoenzyme and ENSA protein complexGang Tian, Xiang Zhang, Hongyue Li, Gang Sun, Lulu Xue, Yufeng Yang, Qiyu Mao, Yan Gao, Lei Sun, Guoliang Xu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progressionJimena Druker, Hao Jiang, Dilem Shakir, Fraser Child, Vanesa Álvarez, Melpomeni Platani, Andrea Corno, Constance Alabert, Adrian Thomas Saurin, Jason R. Swedlow et al. · 2026 · eLife
- The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate recruitmentVandewinkel, Bram, Torrekens, Sophie, Claes, Zander, Bollen, Mathieu, Henckaerts, Els · 2026 · PLOS Pathogens
- Plk1 mitotic phosphorylation in the N-terminal region of the BRCA2 protein : identification, characterization and role in protein interactionsManon Julien · 2021
- Contrôle de l’entrée en division méiotique par les enzymes PKA et PP2A, et leur substrat Arpp19Tom Lemonnier · 2019
- Coordination of the chromosome integrity functions of PLK1 : BRCA2 : PP2A throughout the cell cycleRady Chaaban · 2024
- HTLV-1 intasome recruits the PP2A-B56 holoenzyme and restricts its phosphatase activityJordan James Minnell, Emma K. Punch, Teresa Vanzo, Roghaiyeh Safari, Nora Cronin, P.G. Cherepanov, Goedele N. Maertens · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Liprin-α family proteins and their cellular functionsAbigail Mayer, Yang Zhang, Houhui Xia · 2026 · Journal of Biological Chemistry
- Direct Interaction of Arabidopsis SGO1 with PP2A B′ Subunits Revealed by Microscale ThermophoresisBehzad Heidari, Dugassa Nemie-Feyissa, Cathrine Lillo · 2026 · International Journal of Plant Biology
- Set mediates chromosome alignment and Cohesin cleavage independently of direct PP2A-B56-binding in oocyte meiosisLeonor Keating, Arianna Esposito-Verza, Warif El Yakoubi, Yulia Gryaznova, Safia El Jailani, Damien Cladière, Sandra A. Touati, Eulalie Buffin, Christophe Rachez, Varvara Sarli et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Progressive Loosening of a Dual Autoinhibitory Interface Activates PP2A-B56δMichael S. O’Connor, Cheng-Guo Wu, Yichong Lao, Yongna Xing, Xuhui Huang · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Activator mimicry by PP6 regulatory subunits directs Aurora A dephosphorylation in mitosisTomoaki Sobajima, Gege Yang, Josip Ahel, Elena Poser, Ulrike Grüneberg, Francis A. Barr · 2026 · The EMBO Journal