The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Cell-free synthetic biology: Engineering in an open world
Open accessAbstract
Cell-free synthetic biology emerges as a powerful and flexible enabling technology that can engineer biological parts and systems for life science applications without using living cells. It provides simpler and faster engineering solutions with an unprecedented freedom of design in an open environment than cell system. This review focuses on recent developments of cell-free synthetic biology on biological engineering fields at molecular and cellular levels, including protein engineering, metabolic engineering, and artificial cell engineering. In cell-free protein engineering, the direct control of reaction conditions in cell-free system allows for easy synthesis of complex proteins, toxic proteins, membrane proteins, and novel proteins with unnatural amino acids. Cell-free systems offer the ability to design metabolic pathways towards the production of desired products. Buildup of artificial cells based on cell-free systems will improve our understanding of life and use them for environmental and biomedical applications.
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Citations
Cites
Design and synthesis of a minimal bacterial genome
Hutchison, C. A., Chuang, R.-Y., Noskov, V. N., Assad-Garcia, N., Deerinck, T. J., Ellisman, M. H., Gill, J., Kannan, K., Karas, B. J., Ma, L., et al. (2016) · Science · doi:10.1126/science.aad6253 · Cited by 1,500 · cited 1×
“The top-down approach starts from a living organism and makes a cell with the minimum genome possible to live [49].”
BackgroundFive hard truths for synthetic biology
Kwok, R. (2010) · Nature · doi:10.1038/463288a · Cited by 442
Programmable on-chip DNA compartments as artificial cells
Karzbrun, E., Tayar, A. M., Noireaux, V., & Bar-Ziv, R. H. (2014) · Science · doi:10.1126/science.1255550 · Cited by 264
Multiple Post-translational Modifications Affect Heterologous Protein Synthesis
Tokmakov, A. A., Kurotani, A., Takagi, T., Toyama, M., Shirouzu, M., Fukami, Y., & Yokoyama, S. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.366351 · Cited by 88 · cited 1×
“Cost Modest to high discovery of novel biomolecules [12], flexible strategies for posttranslational modifications [13] and convenient chemical conjugation [14].”
Background
Cited by
Progress in biopharmaceutical development
Kesik‐Brodacka, M. (2018) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.1617 · Cited by 353
Ayoubi‐Joshaghani, M. H., Dianat‐Moghadam, H., Seidi, K., Jahanban‐Esfahalan, A., Zare, P., & Jahanban‐Esfahlan, R. (2020) · Biotechnology and Bioengineering · doi:10.1002/bit.27248 · Cited by 52
Pepe, M., Hesami, M., de la Cerda, K. A., Perreault, M. L., Hsiang, T., & Jones, A. M. P. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108247 · Cited by 36
(2022) · doi:10.1091/mbc.e22-07-0248 · Cited by 15
Metadata
- Authors
- Lu, Y.
- Venue
- Synthetic and Systems Biotechnology
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 2
- Issue
- 1
- Pages
- 23-27
- ISSN
- 2097-1206 (ISSN-L)
- 2405-805X
- OpenAlex
- W2593517473
- Cited by
- 167
- References
- 4
- FWCI
- 5.63
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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