The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Trends in DNA biosensors
Open accessAbstract
Biosensors have witnessed an escalating interest nowadays, both in the research and commercial fields. Deoxyribonucleic acid (DNA) biosensors (genosensors) have been exploited for their inherent physico-chemical stability and suitability to discriminate different organism strains. The main principle of detection among genosensors relies on specific DNA hybridization, directly on the surface of a physical transducer. This review covers the main DNA immobilization techniques reported so far, new micro- and nanotechnological platforms for biosensing and the transduction mechanisms in genosensors. Clinical applications, in particular, demand large-scale and decentralized DNA testing. New schemes for DNA diagnosis include DNA chips and microfluidics, which couples DNA detection with sample pretreatment under in vivo-like hybridization conditions. Higher sensitivity and specificity may arise from nanoengineered structures, like carbon nanotubes (CNTs) and DNA/protein conjugates. A new platform for universal DNA biosensing is also presented, and its implications for the future of molecular diagnosis are argued.
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Cited by
Electrochemistry of Nucleic Acids
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Recent advances in biosensor technology in assessment of early diabetes biomarkers
Salek-Maghsoudi, A., Vakhshiteh, F., Torabi, R., Hassani, S., Ganjali, M. R., Norouzi, P., Hosseini, M., & Abdollahi, M. (2018) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.07.047 · Cited by 174
Biofunctionalization of Multiplexed Silicon Photonic Biosensors
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Metadata
- Authors
- TELES, F., & FONSECA, L.
- Venue
- Talanta
- Publisher
- Elsevier BV
- Published
- 2008-12-15
- Volume
- 77
- Issue
- 2
- Pages
- 606-623
- ISSN
- 0039-9140 (ISSN-L)
- OpenAlex
- W2040498942
- Cited by
- 405
- References
- 84
- FWCI
- 10.92
- Type
- journal article
- Language
- en
- Open access
- green
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