The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Epigenetic transgenerational actions of environmental factors in disease etiology
Open accessAbstract
The ability of environmental factors to promote a phenotype or disease state not only in the individual exposed but also in subsequent progeny for multiple generations is termed transgenerational inheritance. The majority of environmental factors such as nutrition or toxicants such as endocrine disruptors do not promote genetic mutations or alterations in DNA sequence. In contrast, these factors have the capacity to alter the epigenome. Epimutations in the germ line that become permanently programmed can allow transmission of epigenetic transgenerational phenotypes. This review provides an overview of the epigenetics and biology of how environmental factors can promote transgenerational phenotypes and disease.
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Cites
Bird, A. (2007) · Nature · doi:10.1038/nature05913 · Cited by 3,011
The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
Kriaucionis, S., & Heintz, N. (2009) · Science · doi:10.1126/science.1169786 · Cited by 2,700
Environmental epigenomics and disease susceptibility
Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2045 · Cited by 2,492
Self-citationOberlander, T. F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., & Devlin, A. M. (2008) · Epigenetics · doi:10.4161/epi.3.2.6034 · Cited by 1,432
Dolinoy, D. C., Huang, D., & Jirtle, R. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703739104 · Cited by 1,369
Lasting epigenetic influence of early-life adversity on the BDNF gene
Roth, T. L., Lubin, F. D., Funk, A. J., & Sweatt, J. D. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.028 · Cited by 1,273
Ho, S.-M., Tang, W.-Y., Belmonte de Frausto, J., & Prins, G. S. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0516 · Cited by 796
Cited by
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Alegría-Torres, J. A., Baccarelli, A., & Bollati, V. (2011) · Epigenomics · doi:10.2217/epi.11.22 · Cited by 587
Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability
(2011) · Epigenetics · doi:10.4161/epi.6.7.16537 · Cited by 368
Skinner, M. K. (2015) · Genome Biology and Evolution · doi:10.1093/gbe/evv073 · Cited by 342
Self-citationGabory, A., Roseboom, T. J., Moore, T., Moore, L. G., & Junien, C. (2013) · Biology of Sex Differences · doi:10.1186/2042-6410-4-5 · Cited by 344
Metadata
- Authors
- Skinner, M. K., Manikkam, M., & Guerrero-Bosagna, C.
- Venue
- Trends in Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 2010-04
- Volume
- 21
- Issue
- 4
- Pages
- 214-222
- ISSN
- 1043-2760 (ISSN-L)
- OpenAlex
- W2071213636
- Cited by
- 712
- References
- 7
- FWCI
- 3.07
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
