The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Glycine transporters: essential regulators of neurotransmission
Open accessAbstract
Glycine has important neurotransmitter functions at inhibitory and excitatory synapses in the vertebrate central nervous system. The effective synaptic concentrations of glycine are regulated by glycine transporters (GlyTs), which mediate its reuptake into nerve terminals and adjacent glial cells. GlyTs are members of the Na(+)/Cl(-)-dependent transporter family, whose activities and subcellular distributions are regulated by phosphorylation and interactions with other proteins. The analysis of GlyT knockout mice has revealed distinct functions of individual GlyT subtypes in synaptic transmission and provided animal models for two hereditary human diseases, glycine encephalopathy and hyperekplexia. Selective GlyT inhibitors could be of therapeutic value in cognitive disorders, schizophrenia and pain.
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Cites
Structure and Mechanism of the Lactose Permease of Escherichia coli
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Structure of a glutamate transporter homologue from Pyrococcus horikoshii
Yernool, D., Boudker, O., Jin, Y., & Gouaux, E. (2004) · Nature · doi:10.1038/nature03018 · Cited by 783
Molecular Structure and Function of the Glycine Receptor Chloride Channel
Lynch, J. W. (2004) · Physiological Reviews · doi:10.1152/physrev.00042.2003 · Cited by 778
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits
Chatterton, J. E., Awobuluyi, M., Premkumar, L. S., Takahashi, H., Talantova, M., Shin, Y., Cui, J., Tu, S., Sevarino, K. A., Nakanishi, N., et al. (2002) · Nature · doi:10.1038/nature715 · Cited by 694
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GlyR α3: An Essential Target for Spinal PGE 2 -Mediated Inflammatory Pain Sensitization
Harvey, R. J., Depner, U. B., Wässle, H., Ahmadi, S., Heindl, C., Reinold, H., Smart, T. G., Harvey, K., Schütz, B., Abo-Salem, O. M., et al. (2004) · Science · doi:10.1126/science.1094925 · Cited by 598
Self-citationThe glycinergic inhibitory synapse
Legendre, P. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000899 · Cited by 541
Glycine transporters are differentially expressed among CNS cells
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Cited by
Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Glycine receptors: recent insights into their structural organization and functional diversity
Betz, H., & Laube, B. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03908.x · Cited by 288
Self-citationThe solute carrier 6 family of transporters
Bröer, S., & Gether, U. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01975.x · Cited by 269
Stratification of astrocytes in healthy and diseased brain
Verkhratsky, A., Zorec, R., & Parpura, V. (2017) · Brain Pathology · doi:10.1111/bpa.12537 · Cited by 236
Shao, J., Wei, Y., & Wei, X. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111540 · Cited by 58
Metadata
- Authors
- Eulenburg, V., Armsen, W., Betz, H., & Gomeza, J.
- Venue
- Trends in Biochemical Sciences
- Publisher
- Elsevier BV
- Published
- 2005-06
- Volume
- 30
- Issue
- 6
- Pages
- 325-333
- ISSN
- 0968-0004 (ISSN-L)
- OpenAlex
- W1999061814
- Cited by
- 327
- References
- 63
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- green
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- Eulenburg, V., Armsen, W., Betz, H., & Gomeza, J. (2005). Glycine transporters: essential regulators of neurotransmission. Trends in Biochemical Sciences. https://doi.org/10.1016/j.tibs.2005.04.004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
