O-GlcNAc signaling: a metabolic link between diabetes and cancer?

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Items 201–300 of 346

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2. Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice
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3. The post-translational modification O-GlcNAc is a sensor and regulator of metabolism
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4. O-GlcNAc modification is associated with insulin sensitivity in the whole blood of healthy young adult males
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5. Oral glucosamine increases expression of transforming growth factor β1 (TGFβ1) and connective tissue growth factor (CTGF) mRNA in rat cartilage and kidney: Implications for human efficacy and toxicity
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6. ROCK2 mediates osteosarcoma progression and TRAIL resistance by modulating O-GlcNAc transferase degradation.
   Xueqiang Deng, Xuan Yi, Da Huang, Peng Liu, Leifeng Chen, Yunyan Du, Liang Hao · 2020 · PubMed Central
7. Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome
   Heon Shin, Amy Leung, Kevin R Costello, Parijat Senapati, Hiroyuki Kato, Roger E. Moore, Michael Lee, Dimitri Lin, Xiaofang Tang, Patrick Pirrotte et al. · 2023 · eLife
8. The Early Metazoan Trichoplax adhaerens Possesses a Functional O-GlcNAc System
   Nithya Selvan, Daniel Mariappa, Henk van den Toorn, Albert J. R. Heck, Andrew T. Ferenbach, Daan M. F. van Aalten · 2015 · Journal of Biological Chemistry
9. Proteomic analysis of O-GlcNAcylated proteins in invasive ductal breast carcinomas with and without lymph node metastasis
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10. Silencing β-linked N-acetylglucosamine transferase induces apoptosis in human gastric cancer cells through PUMA and caspase-3 pathways
    Ti Wen, Kezuo Hou, Zhi Li, Lu Li, Hanjie Yu, Yunpeng Liu, Yangguang Li, Zhinan Yin · 2015 · Oncology Reports
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13. Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity
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14. O-GlcNAcylation, contractile protein modifications and calcium affinity in skeletal muscle
    Caroline Cieniewski‐Bernard, Matthias R. Lambert, Erwan Dupont, Valérie Montel, L. Stevens, Bruno Bastide · 2014 · Frontiers in Physiology
15. Mapping the UDP-N-acetylglucosamine regulatory site of human glucosamine-6P synthase by saturation-transfer difference NMR and site-directed mutagenesis
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16. Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression
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18. Disruption of O-GlcNAcylation Homeostasis Induced Ovarian Granulosa Cell Injury in Bovine
    Tengfei Wang, Zhi-Qiang Feng, Ya-Wen Sun, Shanjiang Zhao, Huiying Zou, Haisheng Hao, Weihua Du, Xueming Zhao, Huabin Zhu, Yunwei Pang · 2022 · International Journal of Molecular Sciences
19. O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology
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20. Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells
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21. Stable Isotope Labeling with Amino Acids (SILAC)-Based Proteomics of Primary Human Kidney Cells Reveals a Novel Link between Male Sex Hormones and Impaired Energy Metabolism in Diabetic Kidney Disease
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25. Phosphorylation versus O-GlcNAcylation: Computational Insights into the Differential Influences of the Two Competitive Post-Translational Modifications
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26. A widely compatible expression system for the production of highly O-GlcNAcylated recombinant protein in Escherichia coli
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28. O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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29. Sugar modification inhibits autophagosome–lysosome fusion
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30. Proteomic Approaches for Site-Specific O -Glcnacylation Analysis
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31. The effect of streptozotocin-induced hyperglycemia on N-and O-linked protein glycosylation in mouse ovary
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40. Uridine diphosphate release mechanism in O-N-acetylglucosamine (O-GlcNAc) transferase catalysis
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44. Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy
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45. Aralia elata (Miq) Seem Extract Decreases O -GlcNAc Transferase Expression and Retinal Cell Death in Diabetic Mice
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46. Interference of Arabidopsis N-Acetylglucosamine-1-P Uridylyltransferase Expression Impairs Protein N-Glycosylation and Induces ABA-Mediated Salt Sensitivity During Seed Germination and Early Seedling Development
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47. An ultrasensitive colorimetric strategy for protein O-GlcNAcylation detection via copper deposition-enabled nonenzymatic signal amplification
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48. Multiplexed Detection of O-GlcNAcome, Phosphoproteome, and Whole Proteome within the Same Gel
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49. O-GlcNAcylation: Crosstalk between Hemostasis, Inflammation, and Cancer
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50. Inhibition of O-GlcNAc transferase sensitizes prostate cancer cells to docetaxel
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51. Model-based in silico analysis of the PI3K/Akt pathway: the elucidation of cross-talk between diabetes and breast cancer
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55. Measuring O-GlcNAc cleavage by OGA and cell lysates on a peptide microarray
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56. Glycomics: An Overview of the Complex Glycocode
    Garima Gupta, Avadhesha Surolia · 2012 · Advances in experimental medicine and biology
57. Nutrient regulation of transcription and signalling by O-GlcNAcylation
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58. Downregulation of O-linked N-acetylglucosamine transferase by RNA interference decreases MMP9 expression in human esophageal cancer cells
    Zhe Qiao, Chengxue Dang, Bin Zhou, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Yuefeng Ma, Ranran Kong, Zhenchuan Ma · 2016 · Oncology Letters
59. Aralia elata inhibits neurodegeneration by downregulating O-GlcNAcylation of NF-κB in diabetic mice
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62. Site-Specific Stabilization and Destabilization of α Helical Peptides upon Phosphorylation and O-GlcNAcylation
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64. Skeletal Muscle O-GlcNAc Transferase Action on Global Metabolism Is Partially Mediated Through Interleukin-15
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