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The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

The tail of integrin activation

Open access
Anthis, Nicholas J., Campbell, Iain D.·2011·Trends in Biochemical Sciences

Abstract

Integrins are essential adhesion receptors found on the surfaces of all metazoan cells. As regulators of cell migration and extracellular matrix assembly, these membrane-spanning heterodimers are critical for embryonic development, tissue repair and immune responses. Signals transmitted by integrins from outside to inside the cell promote cell survival and proliferation, but integrin affinity for extracellular ligands can also be controlled by intracellular cues. This bidirectional signaling is mediated by the short cytoplasmic tails of the two integrin subunits. Recent structural and functional studies of various integrin fragments and complexes between the cytoplasmic tails and intracellular proteins, such as talin, have provided new insight into the signaling processes centered around the tails, particularly inside-out integrin activation.

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Crossref · 10.1016/j.tibs.2010.11.002

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Metadata

Authors
Anthis, N. J., & Campbell, I. D.
Venue
Trends in Biochemical Sciences
Publisher
Elsevier BV
Published
2011-04
Volume
36
Issue
4
Pages
191-198
ISSN
0968-0004 (ISSN-L)
OpenAlex
W2016715162
Cited by
181
References
7
FWCI
2.27
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The tail of integrin activation. https://app.cochat.ai/papers/10.1016/j.tibs.2010.11.002
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Anthis, N. J., & Campbell, I. D. (2011). The tail of integrin activation. Trends in Biochemical Sciences. https://doi.org/10.1016/j.tibs.2010.11.002

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.