A revival of bispecific antibodies

Kufer, Peter, Lutterbüse, Ralf, Baeuerle, Patrick A.·2004·Trends in Biotechnology
DOI 10.1016/j.tibtech.2004.03.006

Cited by (157)

Items 101–157 of 157

  1. Bispecific Antibodies
    Roland E. Kontermann · 2015 · Springer eBooks
  2. Bispecific Antibodies
    Dafne Müller, Roland E. Kontermann · 2007 · Wiley eBooks
  3. Smarter Drugs
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  4. DOWNSTREAM PROCESSING OF Fc FUSION PROTEINS, BISPECIFIC ANTIBODIES, AND ANTIBODY–DRUG CONJUGATES
    Abhinav A Shukla, Carnley Norman · 2017
  5. Bispecific Antibodies
    Dafne Müller, Roland E. Kontermann · 2014 · Wiley eBooks
  6. Generation of bispecific antibodies by structure-guided redesign of IgG constant regions
    Yordkhwan W. Iwasaki, Kannan Tharakaraman, Vidya Subramanian, Amnart Khongmanee, Andrew Hatas, Eduardo Fleischer, Troy T. Rurak, Patchara Ngok-ngam, Phanthakarn Tit-oon, Mathuros Ruchirawat et al. · 2023 · Frontiers in Immunology
  7. Application of platform process development approaches to the manufacturing of Mabcalin™ bispecifics
    Stefanie Wachter, Thibaut Angevin, Niket Bubna, Adelene Tan, Adam Cichy, David Brown, Leslie S. Wolfe, Ryan Sappington, Edward Lilla, Luke Berry et al. · 2023 · Journal of Biotechnology
  8. Engineering Multivalent and Multispecific Protein Therapeutics
    Cassie J. Liu, Jennifer R. Cochran · 2013 · Springer eBooks
  9. Isolation of highly selective IgNAR variable single-domains against a human therapeutic Fc scaffold and their application as tailor-made bioprocessing reagents
    Magdalena J. Buschhaus, Stefan Becker, A.J. Porter, Caroline Jane Barelle · 2019 · Protein Engineering Design and Selection
  10. Bispecific Antibodies from Hybrid Hybridoma
    Gerhard Moldenhauer · 2011 · Springer eBooks
  11. Bispecific Antibody Armed T Cells to Target Cancer Cells
    Archana B. Thakur, Lawrence G. Lum, Sandeep Mittal · 2017 · Methods in molecular biology
  12. The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers
    Eline van Diest, Mara J.T. Nicolasen, Lovro Kramer, Jiali Zheng, Patricia Hernández-López, Dennis X. Beringer, Jurgen H. E. Kuball · 2023 · Frontiers in Immunology
  13. Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors
    Christina M.P. Ray, Yang Hui-lin, Jamie B. Spangler, Feilim Mac Gabhann · 2024 · PLoS Computational Biology
  14. Expressing and functionally evaluating anticancer bispecific antibody fragments using cyanobacterium Synechocystis sp. PCC6803 for sustainable production
    Kasai, Gota, Shioya, Sayumi, Kobe, Miku, Kobayashi, Shunichi, Takamatsu, Shouhei, Makabe, Koki, Kumagai, Izumi, Sode, Koji, Asano, Ryutaro · 2025 · Biochemical Engineering Journal
  15. Landscape of T-cell engagers in solid tumors
    Esther Garcia-Lorenzo, Miriam Dorta, Bernard Doger, Manuel Pedregal, Victor Moreno · 2026 · The Oncologist
  16. Understanding the structure–property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions
    Bo Zhao, Yunlong Zhao, Stephanie M. Adaniya, Yue Jin Fu, Youmi Moon, Justin Heftel, Shuzhen Chen, Hui Xiao, Ning Li · 2023 · mAbs
  17. Cross‐linking disulfide bonds govern solution structures of diabodies
    Barbara A. Math, Franz Waibl, Leonida M. Lamp, Monica L. Fernández‐Quintero, Klaus Roman Liedl · 2023 · Proteins Structure Function and Bioinformatics
  18. Improvement in soluble expression levels of a diabody by exchanging expression vectors
    Fang Liu, Zhong Chen, Wen G. Jiang, Chunzheng Yang, Dongsheng Xiong, Zhenping Zhu · 2008 · Protein Expression and Purification
  19. The rise of bispecific antibodies for dual targeting, singular impact: technology and clinical advancements
    Abhijeet P. Pandey, Shrikant Wankhade, Aditya Murthy, Barbara Podobnik, Benjamin Sommer, Nora Eifler, Valerie Muller, Andreas Fisch · 2026 · International Immunopharmacology
  20. A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement
    Leili Jia, Yuanyong Xu, Chuanfu Zhang, Yong Wang, Huihui Chong, Shaofu Qiu, Ligui Wang, Yanwei Zhong, Weijing Liu, Yansong Sun et al. · 2010 · Virology Journal
  21. Monoclonal Antibodies in Paediatric Acute Lymphoblastic Leukemia
    Arend von Stackelberg · 2011 · Springer eBooks
  22. Chapter 4: Production Strategies and Challenges with IgG-Based Bispecific Ab Formats
    Chen Gu, Diego A. Ellerman · 2020 · AAPS advances in the pharmaceutical sciences series
  23. Bispecific T Cell Engager for Cancer Therapy
    Patrick A. Baeuerle, Gerhard Zugmaier, Dominik Rüttinger · 2011 · Springer eBooks
  24. Resurgence of Bispecific Antibodies
    Patrick A. Baeuerle, Tobias Raum · 2013
  25. Chemical and Genetic Modification
    Monika Farys, Claire Ginn, George O. Badescu, Karolina Peciak, Estera Pawlisz, Hanieh Khalili, Steve Brocchini · 2013 · Wiley eBooks
  26. Bispecific Antibodies
    Roland E. Kontermann · 2017 · Springer eBooks
  27. Bispecific Antibodies
    Roland E. Kontermann · 2011 · Springer eBooks
  28. Fine-tuning affinity and spacer design enhances T cell potency in DLL3 and BCMA CAR T cells
    Nicholas Mazzanti, Ninkka Tamot, Andrea Francese, Jinquan Luo, M. Jack Borrok, Julie Rossillo, Joseph R. Plummer, Gauri Anand Patwardhan, Chi Shing Sum, Michael O. Ports et al. · 2025 · mAbs
  29. Candidate Biomarkers for Targeting in Type 1 Diabetes; A Bioinformatic Analysis of Pancreatic Cell Surface Antigens.
    Hamed Dabiri, Mahdi Habibi‐Anbouhi, Vahab Ziaei, Zahra Moghadasi, Majid Sadeghizadeh, Ensiyeh Hajizadeh‐Saffar · 2024 · PubMed Central
  30. Fast and Simple Qualitative/Semi‐Quantitative Analysis of Monoclonal Antibody Mixtures Using Liquid Chromatography–Electrospray Triple Time‐of‐Flight Mass Spectrometry
    Jin‐Ju Byeon, Min‐Ho Park, Seok‐Ho Shin, Young Geun Shin · 2018 · Bulletin of the Korean Chemical Society
  31. Antikörper – neue Krebsmedikamente. Gezielt wirksame Biomedizin
    Max Hasmann, Christian Klein, Georg‐Burkhard Kresse · 2009 · Chemie in unserer Zeit
  32. Multiple antibody and multi-specificity approaches
    2012 · Elsevier eBooks
  33. Tailoring Plasmid Design Based on Chain Expression in Cell Line Development for Enhanced Monoclonal and Bispecific Antibody Production
    Shenghai Liu, Qianqian Chen, Lujia Peng, Hongli Li, Bin Zhao, Mengxiao Wu, Yanshen Kang, Ting Hu, Xuefeng Guo, Yanjing Cao et al. · 2025 · Biotechnology Journal
  34. Protein Therapeutics in Oncology
    Michael J. Corbley · 2011 · Springer eBooks
  35. Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV
    Sarah B. Lloyd, Keith P. Niven, Ben R. Kiefel, David C. Montefiori, Arnold Reynaldi, Miles P. Davenport, Stephen John Kent, Wendy R. Winnall · 2017 · Human Vaccines & Immunotherapeutics
  36. Antibody-drug discovery
    Benjamin E. Blass · 2021 · Elsevier eBooks
  37. Targeted delivery of radioisotope or chemotherapeutic loaded prodrug-polymers after pretargeting tumors with bispecific antibody complex
    Keyur S. Gada · 2011
  38. Discovery of New Medicines
    Anand S. Dutta · 2005 · Wiley eBooks
  39. References
    2012 · Elsevier eBooks
  40. Antibody Synthesis in Vitro
    Paz Martínez, Antoni Iborra · 2006 · Encyclopedia of Life Sciences
  41. Bispecific antibodies
    Roland E. Kontermann · 2008 · Springer eBooks
  42. Einfluss des Lym-2 Antigens auf die zytotoxische Aktivität natürlicher Killerzellen gegenüber Leukämien der B-Zellreihe
    Imke Sütterlin · 2010
  43. Thirty Years of Monoclonal Antibodies: A Long Way to Pharmaceutical and Commercial Success
    Uwe Gottschalk, Kirsten Mundt · 2005
  44. Therapeutic Monoclonal Antibodies: Current Perspectives and Applications for the Treatment of Head and Neck Cancer
    Stanislas Blein, Sam Hou · 2011 · International Journal of Head and Neck Surgery
  45. Anticorps bispécifiques : quel avenir ?
    André Pèlegrin, Bruno Robert · 2009 · médecine/sciences
  46. Antibody Synthesis In Vitro
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  47. Redirected T cell activity by high affinity TCR-ANTI-CD3 bispecific candidate therapeutics
    Katherine J. Adams · 2013 · ORCA Online Research @Cardiff (Cardiff University)
  48. Prevalence of possible immune resistance mechanisms of acute leukemias within the context of vaccination strategies using the Wilms tumor gene-1 (WT1)
    Stather, David · 2012 · edoc Publication server (Humboldt University of Berlin)
  49. REVUES Anticorps : quel avenir ?
    André Pèlegrin, Bruno Robert · 2009
  50. Reduction of the cardiotoxicity of Doxorubicin: Demonstration by in vivo imaging with Bispecific antibody/radiolabeled negatively charged polymers
    Rajiv Panwar · 2012
  51. Development of novel bioconjugation strategies for creating cancer-targeting nanomaterials
    Andri Wardiana · 2020 · The University of Queensland
  52. Augmenting therapeutic protein production in CHO cells: A proline‐based selection strategy for enhanced productivity and product quality
    Bin Zhao, Boya Zhang, Yanshen Kang, Shenghai Liu, Zhangying Jia, Chenlin Lu, Yajing Cao, April Xu, Kyu‐Sung Lee, Zheng Zhang et al. · 2025 · Biotechnology Progress
  53. Biological Treatments (Antibodies)
    William A. Paradise, James A. Radosevich · 2013 · Springer eBooks
  54. Antibody-Redirected T-Cell Immunotherapy for Brain Tumors
    Bryan D. Choi · 2014 · DukeSpace (Duke University)
  55. Design and Evaluation of Domain-Rearranged Bispecific Antibody Fragments for Functional Optimization
    Ryutaro Asano · 2026 · Methods in molecular biology
  56. DOWNSTREAM PROCESSING OF Fc FUSION PROTEINS, BISPECIFIC ANTIBODIES, AND ANTIBODY–DRUG CONJUGATES
    Abhinav A Shukla, Carly M. Catella · 2026
  57. Recent immunoglobulin G1 engineering strategies to modulate immune effector functions for therapeutics
    Alexander R. Davis, Adam W. Barb · 2026 · Glycobiology