The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification
Open accessAbstract
Biocatalysis has widened its scope and relevance since new molecular tools, including improved expression systems for proteins, protein and metabolic engineering, and rational techniques for immobilization, have become available. However, applications are still sometimes hampered by low productivity and difficulties in scaling up. A practical and reasonable step to improve the performances of biocatalysts (including both enzymes and whole-cell systems) is to use them in flow reactors. This review describes the state of the art on the design and use of biocatalysis in flow reactors. The encouraging successes of this enabling technology are critically discussed, highlighting new opportunities, problems to be solved and technological advances.
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Citations
Cites
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On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
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Taming hazardous chemistry by continuous flow technology
Movsisyan, M., Delbeke, E. I. P., Berton, J. K. E. T., Battilocchio, C., Ley, S. V., & Stevens, C. V. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00902b · Cited by 692
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Cited by
Extending the application of biocatalysis to meet the challenges of drug development
Devine, P. N., Howard, R. M., Kumar, R., Thompson, M. P., Truppo, M. D., & Turner, N. J. (2018) · Nature Reviews Chemistry · doi:10.1038/s41570-018-0055-1 · Cited by 426
Britton, J., Majumdar, S., & Weiss, G. A. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00906b · Cited by 389
Biocatalysis with Laccases: An Updated Overview
Bassanini, I., Ferrandi, E. E., Riva, S., & Monti, D. (2020) · Catalysts · doi:10.3390/catal11010026 · Cited by 139
Wang, D., Zhang, H., Wang, Y., Pinelo, M., Mazzei, R., Fan, R., Wan, Y., & Luo, J. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.160844 · Cited by 19
Metadata
- Authors
- Tamborini, L., Fernandes, P., Paradisi, F., & Molinari, F.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 36
- Issue
- 1
- Pages
- 73-88
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2765697954
- Cited by
- 328
- References
- 51
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Tamborini, L., Fernandes, P., Paradisi, F., & Molinari, F. (2018). Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2017.09.005
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
