The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Combining Environmental and Economic Performance for Bioprocess Optimization
Open accessAbstract
Biochemical production faces economic and environmental challenges that need to be overcome to enable a viable and sustainable bioeconomy. We propose an assessment framework that consistently combines environmental and economic indicators to support optimized biochemical production at early development stages. We define internally consistent system boundaries and a comprehensive set of quantitative indicators from life cycle assessment (LCA) and techno-economic assessment (TEA) to combine environmental and economic performance in a single score. Our framework enables the identification of trade-offs across environmental and economic aspects over the entire biochemical life cycle. This approach provides input for the optimization of future biochemicals in terms of overall sustainability, to overcome prevailing obstacles in the development of biochemical production processes.
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“Advances in technology, scale, and feedstock availability can all assist in reducing production costs and increasing competitiveness [120].”
From Biofuel production: exploring renewable energy solutions for a greener future (2024) · cites this paper as [120]
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Lignin Valorization: Improving Lignin Processing in the Biorefinery
Ragauskas, A. J., Beckham, G. T., Biddy, M. J., Chandra, R. P., Chen, F., Davis, M. F., Davison, B. H., Dixon, R. A., Gilna, P., Keller, M., et al. (2014) · Science · doi:10.1126/science.1246843 · Cited by 4,250
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Sustainability assessments of bio-based polymers
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One decade of multi-objective calibration approaches in hydrological modelling: a review
Efstratiadis, A., & Koutsoyiannis, D. (2010) · Hydrological Sciences Journal · doi:10.1080/02626660903526292 · Cited by 524
Potentials of macroalgae as feedstocks for biorefinery
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Opportunities, recent trends and challenges of integrated biorefinery: Part I
Maity, S. K. (2014) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2014.11.092 · Cited by 468
Analyzing the design and management of biomass-to-biorefinery supply chain
Ekşioğlu, S. D., Acharya, A., Leightley, L. E., & Arora, S. (2009) · Computers & Industrial Engineering · doi:10.1016/j.cie.2009.07.003 · Cited by 428
Cost benefit analysis and environmental policy
Pearce, D. (1998) · Oxford Review of Economic Policy · doi:10.1093/oxrep/14.4.84 · Cited by 379
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Lin, S., Hizaddin, H. F., & Abidin, M. I. I. Z. (2026) · Process Safety and Environmental Protection · doi:10.1016/j.cherd.2026.06.036
Pranowo, D., Azharani, T. R., Sukardi, Setyawan, H. Y., & Jung, Y. H. (2026) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2026.07.014
Theodosiou, E., Itzenhäuser, M. A., Linke, T., Stauder, R., & Schmid, A. (2026) · Biocatalysis and Biotransformation · doi:10.1080/10242422.2026.2710089
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Sánchez, D., de Arriba, P. R., Florenciano, A. L., Schifflechner, C., & McBay, D. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40590-7.00007-0
Flores, B. C., Vargas, J. C. J., Aleman-Gonzales, L., Panca, P. H., Paredes-Quispe, J. R., Vilca, E. M., & Torres-Cruz, E. (2026) · Journal Of Biochemical Technology · doi:10.51847/mlfk6ryuap
Kumar, P., Kumar, S., Prabhakar, P., Verma, D. K., Utama, G. L., González, M. L. C., & Aguilar, C. N. (2026) · World sustainability series · doi:10.1007/978-3-032-26142-7_4
Metadata
- Authors
- Ögmundarson, Ó., Sukumara, S., Herrgård, M. J., & Fantke, P.
- Affiliations
- Novo Nordisk Foundation (DK)
- Technical University of Denmark (DK)
- Corresponding author
- Ögmundarson, Ólafur
- Fantke, Peter
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 38
- Issue
- 11
- Pages
- 1203-1214
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W3024228537
- Cited by
- 110
- References
- 78
- Citations by year
- 2026: 17 · 2025: 20 · 2024: 18 · 2023: 19 · 2022: 18 · 2021: 11 · 2020: 7
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Trends in biotechnology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion, other-oa)
- Funders
- Novo Nordisk Fonden (NNF10CC1016517)
- Topics
- Physical Sciences › Environmental Science › Environmental Engineering › Environmental Impact and Sustainability
- Life Sciences › Agricultural and Biological Sciences › General Agricultural and Biological Sciences › Bioeconomy and Sustainability Development
- Physical Sciences › Environmental Science › Environmental Chemistry › Chemistry and Chemical Engineering
- Keywords
- bioprocess optimization, biochemical production, bioeconomy, sustainability assessment, life cycle assessment, techno-economic analysis, system boundaries, economic-environmental trade-off, early developmental stages, sustainability score
- MeSH terms
- Sustainable Development, Biochemical Phenomena, Biochemistry, Chemical Industry, Economics, Environment, Humans
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