The DOI matches its Crossref record; 175 of the 175 references it cites were found in a registry or an index.
Nuclear Long Noncoding RNAs: Key Regulators of Gene Expression
Open accessAbstract
A significant portion of the human genome encodes genes that transcribe long non-protein coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched on the chromatin or localized to specific sub-nuclear compartments. Nuclear lncRNAs participate in several biological processes, including chromatin organization, transcriptional and post-transcriptional gene expression, and also act as structural scaffolds of nuclear domains. Here, we highlight recent studies demonstrating the role of lncRNAs in regulating gene expression and nuclear organization in mammalian cells. In addition, we update current knowledge about the involvement of the most abundant and conserved lncRNA, MALAT1, in gene expression control.
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2 retracted
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Metadata
- Authors
- Sun, Q., Hao, Q., & Prasanth, K. V.
- Venue
- Trends in Genetics
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 34
- Issue
- 2
- Pages
- 142-157
- ISSN
- 0168-9525 (ISSN-L)
- OpenAlex
- W2774855547
- Cited by
- 565
- References
- 175
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- green
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