Innate immune detection of microbial nucleic acids
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IFI16 regulates cell proliferation and transcription through different interactions with p53 and STAT3.
“It regulates cell proliferation and transcription through different interactions with p53 and STAT3.”
From Transcriptomic analysis of purified human cortical microglia reveals age-associated changes (2017) · cites this paper as [44]
IFI16 (p204) is associated with viral infection and the response to cytosolic double-stranded DNA.
“IFI16 (p204) is associated with viral infection and the response to cytosolic double-stranded DNA 44 .”
From Transcriptomic analysis of purified human cortical microglia reveals age-associated changes (2017) · cites this paper as [44]
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Cites
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A Toll-like receptor recognizes bacterial DNA
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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E., & Fitzgerald, K. A. (2009) · Nature · doi:10.1038/nature07725 · Cited by 2,627 · see citing works
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5’-phosphates
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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., & Alnemri, E. S. (2009) · Nature · doi:10.1038/nature07710 · Cited by 1,831 · see citing works
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
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TLR13 Recognizes Bacterial 23 <i>S</i> rRNA Devoid of Erythromycin Resistance–Forming Modification
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Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN
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Control of adaptive immunity by the innate immune system
Iwasaki, A., & Medzhitov, R. (2015) · Nature Immunology · doi:10.1038/ni.3123 · Cited by 2,160 · see citing works
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
Galatro, T. F., Holtman, I. R., Lerario, A. M., Vainchtein, I. D., Brouwer, N., Sola, P. R., Veras, M. M., Pereira, T. F., Leite, R. E. P., Möller, T., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4597 · Cited by 741 · see citing works
Matsumoto, M., Tatematsu, M., Nishikawa, F., Azuma, M., Ishii, N., Morii-Sakai, A., Shime, H., & Seya, T. (2015) · Nature Communications · doi:10.1038/ncomms7280 · Cited by 130 · see citing works
Bode, C., Fox, M., Tewary, P., Steinhagen, A., Ellerkmann, R. K., Klinman, D., Baumgarten, G., Hornung, V., & Steinhagen, F. (2016) · European Journal of Immunology · doi:10.1002/eji.201546113 · Cited by 79 · see citing works
- Authors
- Gürtler, C., & Bowie, A. G.
- Venue
- Trends in Microbiology
- Publisher
- Elsevier BV
- Published
- 2013-08
- Volume
- 21
- Issue
- 8
- Pages
- 413-420
- ISSN
- 0966-842X
- PMC
- PMC3735846
- Cited by
- 236
- References
- 12
- Language
- en
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