The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Towards Understanding MCR-like Colistin Resistance
Abstract
Antibiotic resistance has become a global public health priority. Polymyxins, a family of cationic polypeptide antibiotics, act as a final line of refuge against severe infections by Gram-negative pathogens with pan-drug resistance. Unfortunately, this last-resort antibiotic has been challenged by the emergence and global spread of mobilized colistin resistance determinants (mcr). Given the fact that it has triggered extensive concerns worldwide, we present here an updated view of MCR-like colistin resistance. These studies provide a basic framework for understanding the molecular epidemiology and resistance mechanism of MCR-like genes. However, further large-scale epidemiology and functional studies are urgently needed to better understand the biology of this clinically important antibiotic resistance.
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Citations
Cites
Kluyvera ascorbata Strain from Hospital Sewage Carrying the mcr-1 Colistin Resistance Gene
Zhao, F., & Zong, Z. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01165-16 · Cited by 53
Cited by
Distribution of antibiotic resistance genes in the environment
Zhuang, M., Achmon, Y., Cao, Y., Liang, X., Chen, L., Wang, H., Siame, B. A., & Leung, K. Y. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117402 · Cited by 422
Metadata
- Authors
- Sun, J., Zhang, H., Liu, Y.-H., & Feng, Y.
- Venue
- Trends in Microbiology
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 26
- Issue
- 9
- Pages
- 794-808
- ISSN
- 0966-842X (ISSN-L)
- OpenAlex
- W2789500779
- Cited by
- 446
- References
- 1
- FWCI
- 6.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sun, J., Zhang, H., Liu, Y.-H., & Feng, Y. (2018). Towards Understanding MCR-like Colistin Resistance. Trends in Microbiology. https://doi.org/10.1016/j.tim.2018.02.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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