Cytoprotective protein C pathways and implications for stroke and neurological disorders

Zlokovic, Berislav V., Griffin, John H.·2011·Trends in Neurosciences
DOI 10.1016/j.tins.2011.01.005

Cited by (128)

Items 101–128 of 128

  1. Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway
    Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li · 2021 · Experimental and Therapeutic Medicine · Retracted
  2. The effects of thrombomodulin and activated protein C on the pathogenesis of multiple sclerosis
    Ece Balkuv, Asuman Orhan Varoğlu, Nihal Işık, Banu İşbilen Başok, Saadettin Dürüyen, Recep Başaran, Abdülkadir Koçer · 2016 · Multiple Sclerosis and Related Disorders
  3. Biology of Coagulation and Coagulopathy in Neurologic Surgery
    Ammon M. Fager, Maureane Hoffman · 2018 · Neurosurgery Clinics of North America
  4. Neuroprotective Effects of Noncanonical PAR1 Agonists on Cultured Neurons in Excitotoxicity
    Irina Babkina, Irina G. Savinkova, Tatiana Molchanova, Maria V. Sidorova, Alexander M. Surin, Л. Р. Горбачева · 2024 · International Journal of Molecular Sciences
  5. Neuroprotection and vasculoprotection using genetically targeted protease-ligands
    Padmesh S. Rajput, Jessica A. Lamb, José A. Fernández, Jilin Bai, Benedict Pereira, I-Farn Lei, Jennifer Leung, John H. Griffin, Patrick D. Lyden · 2019 · Brain Research
  6. 3K3A-Activated Protein C Inhibits Choroidal Neovascularization Growth and Leakage and Reduces NLRP3 Inflammasome, IL-1β, and Inflammatory Cell Accumulation in the Retina
    Yehonatan Weinberger, Ivan Budnik, Yael Nisgav, Dahlia Palevski, Gil Ben-David, José A. Fernández, Shany Nivinsky Margalit, Sarina Levy‐Mendelovich, Gili Kenet, Dov Weinberger et al. · 2023 · International Journal of Molecular Sciences
  7. Antibody SPC-54 provides acute in vivo blockage of the murine protein C system
    Laurent Burnier, José A. Fernández, John H. Griffin · 2013 · Blood Cells Molecules and Diseases
  8. Influence of the 3K3A‐activated protein C variant on the plasma clot lysis activity of t‐PA and of t‐PA on the variant's anticoagulant activity
    Laurent O. Mosnier, José A. Fernández, Thomas P. Davis, Berislav V. Zloković, John H. Griffin · 2013 · Journal of Thrombosis and Haemostasis
  9. Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells
    Mukesh K. Sriwastva, Remesh Kunjunni, Mutahar Andrabi, Kameshwar Prasad, Renu Saxena, Vivekanandhan Subbiah · 2020 · Brain Sciences
  10. Activation-resistant homozygous protein C R229W mutation causing familial perinatal intracranial hemorrhage and delayed onset of thrombosis
    Abdulrahman S. Alsultan, Andrew J. Gale, Kadijah Kurban, Mohammed Khalifah, Fahad B. AlBadr, John H. Griffin · 2016 · Thrombosis Research
  11. Activated protein C ameliorates diabetes-induced atherosclerosis by sustaining macrophage efferocytosis
    Saira Ambreen, Amna Arif, Saikal Shamkeeva, Ahmed Elwakiel, Surinder Pal, Shihai Jiang, Muhammad Asad Farhan, Zuhir Halloul, John H. Griffin, Berend Heinrich Isermann et al. · 2025 · Cardiovascular Diabetology
  12. Evaluation of 3K3A-Activated Protein C to Treat Neonatal Hypoxic Ischemic Brain Injury in the Spiny Mouse
    Stacey J. Ellery, Madeleine G. Goss, Nadine Brew, Hayley Dickinson, Nadia Hale, Domenic A. LaRosa, David W. Walker, Flora Y. Wong · 2018 · Neurotherapeutics
  13. Protective effects of activated protein C on neurovascular unit in a rat model of intrauterine infection-induced neonatal white matter injury
    Shengjuan Jin, Yan Liu, Shihua Deng, Tulian Lin, Abid Rashid, Lihong Liao, Qin Ning, Xiaoping Luo · 2015 · Journal of Huazhong University of Science and Technology [Medical Sciences]
  14. Peptides analogous to tethered ligands liberated by activated protein C exert neuroprotective effects in glutamate-induced excitotoxicity
    Irina G. Savinkova, Л. Р. Горбачева, Zhanna D. Bespalova, Vsevolod G. Pinelis, Svetlana M. Strukova · 2014 · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology
  15. New PAR1 Agonist Peptide Demonstrates Protective Action in a Mouse Model of Photothrombosis-Induced Brain Ischemia
    Maksim Galkov, Ekaterina V. Kiseleva, Mikhail V. Gulyaev, Maria V. Sidorova, Л. Р. Горбачева · 2020 · Frontiers in Neuroscience
  16. Intractome Curation and Analysis for Stroke and Spinal Cord Injury Using Semiautomatic Annotations
    Mohamed Sabra, Ali Mostafa Alawieh, Fadi A. Zaraket · 2018 · Elsevier eBooks
  17. PKCε inhibition prevents ischemia‑induced dendritic spine impairment in cultured primary neurons
    Chenjie Ge, Xuefeng Wang, Yun-Hong Wang, Lilei Lei, Guohua Song, Mincai Qian, Shiliang Wang · 2023 · Experimental and Therapeutic Medicine
  18. Anti-Inflammatory Actions of the Anticoagulant, Activated Protein C
    Christopher D. John, Meilang Xue · 2011 · InTech eBooks
  19. Gain in translation: heme oxygenase‐1 induced by activated protein C promotes thrombus resolution
    Hiroshi Deguchi, Darlene J. Elias, John H. Griffin · 2013 · Journal of Thrombosis and Haemostasis
  20. Glial Support of Blood–Brain Barrier Integrity: Molecular Targets for Novel Therapeutic Strategies in Stroke
    Patrick T. Ronaldson, Thomas P. Davis · 2016 · Springer series in translational stroke research
  21. Paying Homage to Microvessel Remodeling and Small Vessel Disease in Neurodegeneration: Implications for the Development of Late-Onset Alzheimer’s Disease
    Melvin Ray Hayden · 2024 · Journal of Vascular Diseases
  22. Bidirectional Pathologic Effects of Thrombin
    Chiaki Hidai · 2018 · Anatomy & Physiology
  23. Effects of anti-inflammatory treatments on stroke outcome in animal models
    Ivo ACW Tiebosch · 2012 · Utrecht University Repository (Utrecht University)
  24. Downregulation of the clotting cascade by the protein C
    Fabian Stavenuiter · 2013
  25. Low-Dose Activated Protein C Suppresses the Development of Cerebral Infarction and Neurological Deficits in Mice
    Keiko Yamato, Yukako Nakajo, Hitomi Yamamoto‐Imoto, Koichi Kokame, Toshiyuki Miyata, JUN C. TAKAHASHI, Hiroharu Kataoka, Hiroji Yanamoto · 2020 · Neurosurgery Practice
  26. APC Overexpression Suppresses the Pyroptosis of Subarachnoid Hemorrhage Model Cells through Regulating NLRP3 Inflammasome Pathway
    Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li · 2021 · Research Square
  27. E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis
    Norah G. Verbout, Weiping Su, Peter T. Pham, Kelley R. Jordan, Tia C. L. Kohs, Erik I. Tucker, Owen J. T. McCarty, Larry S. Sherman · 2023 · Research Square
  28. Advances in the biological functions and clinical applications of protein C
    Yi-Shu XU, Arial Yi ZENG · 2026 · Shengming kexue