The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.
The Parabrachial Nucleus: CGRP Neurons Function as a General Alarm
Open accessAbstract
The parabrachial nucleus (PBN), which is located in the pons and dissected by one of the major cerebellar output tracks, is known to relay sensory information (visceral malaise, taste, temperature, pain, itch) to forebrain structures including the thalamus, hypothalamus and extended amygdala. The availability of mouse lines expressing Cre-recombinase selectively in subsets of PBN neurons and of Cre-dependent viruses that allow circuit mapping and manipulation of neuron function is beginning to reveal the connectivity and functions of PBN’s component neurons. This review focuses on the PBN neurons that express calcitonin gene-related protein (CGRPPBN) that play a major role in regulating appetite and transmitting real or potential threat signals to the extended amygdala. The functions of other specific PBN neuronal populations are also discussed. This review aims to encourage investigation of the numerous unanswered questions that are becoming accessible.
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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
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Self-citationProduction of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
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RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
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From circuits to behaviour in the amygdala
Janak, P. H., & Tye, K. M. (2015) · Nature · doi:10.1038/nature14188 · Cited by 2,011
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 3-Year Outcomes
Schauer, P. R., Bhatt, D. L., Kirwan, J. P., Wolski, K., Brethauer, S. A., Navaneethan, S. D., Aminian, A., Pothier, C. E., Kim, E. S. H., Nissen, S. E., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1401329 · Cited by 1,901
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GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
Patel, S., Alvarez-Guaita, A., Melvin, A., Rimmington, D., Dattilo, A., Miedzybrodzka, E. L., Cimino, I., Maurin, A.-C., Roberts, G. P., Meek, C. L., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2018.12.016 · Cited by 509
CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond
Russo, A. F., & Hay, D. L. (2023) · Physiological Reviews · doi:10.1152/physrev.00059.2021 · Cited by 382
Area postrema cell types that mediate nausea-associated behaviors
Zhang, C., Kaye, J. A., Cai, Z., Wang, Y., Prescott, S. L., & Liberles, S. D. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.010 · Cited by 263
GDF15: a hormone conveying somatic distress to the brain
Lockhart, S. M., Saudek, V., & O’Rahilly, S. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa007 · Cited by 256
The physiological control of eating: signals, neurons, and networks
Watts, A. G., Kanoski, S. E., Sanchez-Watts, G., & Langhans, W. (2022) · Physiological Reviews · doi:10.1152/physrev.00028.2020 · Cited by 168
Metadata
- Authors
- Palmiter, R. D.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 41
- Issue
- 5
- Pages
- 280-293
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W2800979197
- Cited by
- 431
- References
- 138
- FWCI
- 4.21
- Type
- journal article
- Language
- en
- Open access
- bronze
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