The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
Artemisinins: their growing importance in medicine
Open accessAbstract
Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well established for the treatment of malaria, including highly drug-resistant strains. Their efficacy also extends to phylogenetically unrelated parasitic infections such as schistosomiasis. More recently, they have also shown potent and broad anticancer properties in cell lines and animal models. In this review, we discuss recent advances in defining the role of artemisinins in medicine, with particular focus on their controversial mechanisms of action. This safe and cheap drug class that saves lives at risk from malaria can also have important potential in oncology.
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Cites
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Cited by
Artemisinins: Pharmacological actions beyond anti-malarial
Ho, W. E., Peh, H. Y., Chan, T. K., & Wong, W. S. F. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.12.001 · Cited by 481
Discovery, mechanisms of action and combination therapy of artemisinin
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Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis
Ivanescu, B., Miron, A., & Corciova, A. (2015) · Journal of Analytical Methods in Chemistry · doi:10.1155/2015/247685 · Cited by 201
“Several in vitro studies showed that artemisinin has antiviral effect on hepatitis B and C viruses [92, 93], a range of human herpes viruses (human cytomegalovirus, herpes simplex virus type 1, and EpsteinBarr virus) [94–96], influenza virus A [97], and a bovine viral diarrhea virus [98] in the low micromolar range.”
BackgroundInhibitors of Mycobacterium tuberculosis DosRST signaling and persistence
Zheng, H., Colvin, C. J., Johnson, B. K., Kirchhoff, P. D., Wilson, M., Jorgensen-Muga, K., Larsen, S. D., & Abramovitch, R. B. (2017) · Nature Chemical Biology · doi:10.1038/nchembio.2259 · Cited by 169
Nanotechnology for delivery of natural therapeutic substances: a review
Saka, R., & Chella, N. (2021) · Environmental Chemistry Letters · doi:10.1007/s10311-020-01103-9 · Cited by 74
Metadata
- Authors
- Krishna, S., Bustamante, L., Haynes, R. K., & Staines, H. M.
- Venue
- Trends in Pharmacological Sciences
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 29
- Issue
- 10
- Pages
- 520-527
- ISSN
- 0165-6147 (ISSN-L)
- OpenAlex
- W2051905139
- Cited by
- 388
- References
- 92
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
