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Cited by 276

The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.

Amphetamines, new psychoactive drugs and the monoamine transporter cycle

Open access
Sitte, Harald H., Freissmuth, Michael·2015·Trends in Pharmacological Sciences
DOI 10.1016/j.tips.2014.11.006
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Abstract

In monoaminergic neurons, the vesicular transporters and the plasma membrane transporters operate in a relay. Amphetamine and its congeners target this relay to elicit their actions: most amphetamines are substrates, which pervert the relay to elicit efflux of monoamines into the synaptic cleft. However, some amphetamines act as transporter inhibitors. Both compound classes elicit profound psychostimulant effects, which render them liable to recreational abuse. Currently, a surge of new psychoactive substances occurs on a global scale. Chemists bypass drug bans by ingenuous structural variations, resulting in a rich pharmacology. A credible transport model must account for their distinct mode of action and link this to subtle differences in activity and undesired, potentially deleterious effects.

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Crossref · 10.1016/j.tips.2014.11.006

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Metadata

Authors
Sitte, H. H., & Freissmuth, M.
Venue
Trends in Pharmacological Sciences
Publisher
Elsevier BV
Published
2015-01
Volume
36
Issue
1
Pages
41-50
ISSN
0165-6147 (ISSN-L)
DOI
10.1016/j.tips.2014.11.006
OpenAlex
W2059248417
Cited by
276
References
92
FWCI
1.86
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Amphetamines, new psychoactive drugs and the monoamine transporter cycle. https://app.cochat.ai/papers/10.1016/j.tips.2014.11.006
The paper
Sitte, H. H., & Freissmuth, M. (2015). Amphetamines, new psychoactive drugs and the monoamine transporter cycle. Trends in Pharmacological Sciences. https://doi.org/10.1016/j.tips.2014.11.006

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.