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Cited by 330

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The CBL–CIPK Calcium Signaling Network: Unified Paradigm from 20 Years of Discoveries

Tang, Ren-Jie, Wang, Chao, Li, Kunlun, Luan, Sheng·2020·Trends in Plant Science

Abstract

Calcium (Ca2+) serves as an essential nutrient as well as a signaling agent in all eukaryotes. In plants, calcineurin B-like proteins (CBLs) are a unique group of Ca2+ sensors that decode Ca2+ signals by activating a family of plant-specific protein kinases known as CBL-interacting protein kinases (CIPKs). Interactions between CBLs and CIPKs constitute a signaling network that enables information integration and physiological coordination in response to a variety of extracellular cues such as nutrient deprivation and abiotic stresses. Studies in the past two decades have established a unified paradigm that illustrates the functions of CBL-CIPK complexes in controlling membrane transport through targeting transporters and channels in the plasma membrane and tonoplast.

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Metadata

Authors
Tang, R.-J., Wang, C., Li, K., & Luan, S.
Venue
Trends in Plant Science
Publisher
Elsevier BV
Published
2020-06
Volume
25
Issue
6
Pages
604-617
ISSN
1360-1385 (ISSN-L)
OpenAlex
W3012169111
Cited by
330
References
2
FWCI
5.36
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The CBL–CIPK Calcium Signaling Network: Unified Paradigm from 20 Years of Discoveries. https://app.cochat.ai/papers/10.1016/j.tplants.2020.01.009
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Tang, R.-J., Wang, C., Li, K., & Luan, S. (2020). The CBL–CIPK Calcium Signaling Network: Unified Paradigm from 20 Years of Discoveries. Trends in Plant Science. https://doi.org/10.1016/j.tplants.2020.01.009

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