Smartphone-based biosensors: A critical review and perspectives

Simple Telemedicine for Developing Regions: Camera Phones and Paper-Based Microfluidic Devices for Real-Time, Off-Site Diagnosis

Martinez, A. W., Phillips, S. T., Carrilho, E., Thomas, S. W., Sindi, H., & Whitesides, G. M. (2008) · Analytical Chemistry · doi:10.1021/ac800112r · Cited by 1,445

Mobile Phone Based Clinical Microscopy for Global Health Applications

Breslauer, D. N., Maamari, R. N., Switz, N. A., Lam, W. A., & Fletcher, D. A. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006320 · Cited by 694

Point-of-care colorimetric detection with a smartphone

Shen, L., Hagen, J. A., & Papautsky, I. (2012) · Lab on a Chip · doi:10.1039/c2lc40741h · Cited by 610

Electrogenerated Chemiluminescence Detection in Paper-Based Microfluidic Sensors

Delaney, J. L., Hogan, C. F., Tian, J., & Shen, W. (2011) · Analytical Chemistry · doi:10.1021/ac102392t · Cited by 592

Detection of Mercury(II) Ions Using Colorimetric Gold Nanoparticles on Paper-Based Analytical Devices

Chen, G., Chen, W., Yen, Y.-C., Wang, C., Chang, H., & Chen, C. (2014) · Analytical Chemistry · doi:10.1021/ac5008688 · Cited by 514

Lensfree microscopy on a cellphone

Tseng, D. K., Mudanyali, O., Oztoprak, C., Isikman, S. O., Şencan, İ., Yaglidere, O., & Özcan, A. (2010) · Lab on a Chip · doi:10.1039/c003477k · Cited by 480

Integrated rapid-diagnostic-test reader platform on a cellphone

Mudanyali, O., Dimitrov, S., Sikora, U., Padmanabhan, S., Navruz, I., & Ozcan, A. (2012) · Lab on a Chip · doi:10.1039/c2lc40235a · Cited by 426

Detection and Spatial Mapping of Mercury Contamination in Water Samples Using a Smart-Phone

Wei, Q., Nagi, R., Sadeghi, K., Feng, S. W., Yan, E., Ki, S. J., Caire, R., Tseng, D. K., & Özcan, A. (2014) · ACS Nano · doi:10.1021/nn406571t · Cited by 416

Optofluidic Fluorescent Imaging Cytometry on a Cell Phone

Zhu, H., Mavandadi, S., Coskun, A. F., Yaglidere, O., & Özcan, A. (2011) · Analytical Chemistry · doi:10.1021/ac201587a · Cited by 404

A simple and compact smartphone accessory for quantitative chemiluminescence-based lateral flow immunoassay for salivary cortisol detection

Zangheri, M., Cevenini, L., Anfossi, L., Baggiani, C., Simoni, P., Di Nardo, F., & Roda, A. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.08.048 · Cited by 373

Smartphone based health accessory for colorimetric detection of biomarkers in sweat and saliva

Oncescu, V., O’Dell, D., & Erickson, D. (2013) · Lab on a Chip · doi:10.1039/c3lc50431j · Cited by 362

Cost-effective and compact wide-field fluorescent imaging on a cell-phone

Zhu, H., Yaglidere, O., Su, T., Tseng, D. K., & Özcan, A. (2010) · Lab on a Chip · doi:10.1039/c0lc00358a · Cited by 330

Label-free biodetection using a smartphone

Gallegos, D., Long, K. D., Yu, H., Clark, P. P., Lin, Y., George, S., Nath, P., & Cunningham, B. T. (2013) · Lab on a Chip · doi:10.1039/c3lc40991k · Cited by 311

Cellphone-based devices for bioanalytical sciences

Vashist, S. K., Mudanyali, O., Schneider, E. M., Zengerle, R., & Özcan, A. (2013) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-013-7473-1 · Cited by 302

Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array

Bishara, W., Sikora, U., Mudanyali, O., Su, T., Yaglidere, O., Luckhart, S., & Özcan, A. (2011) · Lab on a Chip · doi:10.1039/c0lc00684j · Cited by 286

A personalized food allergen testing platform on a cellphone

Coskun, A. F., Wong, J., Khodadadi, D., Nagi, R., Tey, A., & Özcan, A. (2012) · Lab on a Chip · doi:10.1039/c2lc41152k · Cited by 280

Cholesterol testing on a smartphone

Oncescu, V., Mancuso, M., & Erickson, D. (2013) · Lab on a Chip · doi:10.1039/c3lc51194d · Cited by 279

Rapid electrochemical detection on a mobile phone

Lillehoj, P. B., Huang, M.-C., Truong, N., & Ho, C. (2013) · Lab on a Chip · doi:10.1039/c3lc50306b · Cited by 261

Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management

Vashist, S. K., Schneider, E. M., & Luong, J. H. T. (2014) · Diagnostics · doi:10.3390/diagnostics4030104 · Cited by 247

Portable smartphone quantitation of prostate specific antigen (PSA) in a fluoropolymer microfluidic device

Barbosa, A. I., Gehlot, P., Sidapra, K., Edwards, A. D., & Reis, N. M. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.03.006 · Cited by 227

Integrating Biochemiluminescence Detection on Smartphones: Mobile Chemistry Platform for Point-of-Need Analysis

Roda, A., Michelini, E., Cevenini, L., Calabria, D., Calabretta, M. M., & Simoni, P. (2014) · Analytical Chemistry · doi:10.1021/ac502137s · Cited by 222

Advances in Smartphone-Based Point-of-Care Diagnostics

Xu, X., Akay, A. R., Wei, H., Wang, S., Pingguan‐Murphy, B., Erlandsson, B.-E., Li, X., Lee, W. G., Hu, J., Wang, L., et al. (2015) · Proceedings of the IEEE · doi:10.1109/jproc.2014.2378776 · Cited by 219

Albumin testing in urine using a smart-phone

Coskun, A. F., Nagi, R., Sadeghi, K., Phillips, S. W., & Özcan, A. (2013) · Lab on a Chip · doi:10.1039/c3lc50785h · Cited by 211

A 3D-printed device for a smartphone-based chemiluminescence biosensor for lactate in oral fluid and sweat

Roda, A., Guardigli, M., Calabria, D., Calabretta, M. M., Cevenini, L., & Michelini, E. (2014) · The Analyst · doi:10.1039/c4an01612b · Cited by 206

Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications

Branchini, B. R., Ablamsky, D. M., Murtiashaw, M. H., Uzasci, L., Fraga, H., & Southworth, T. L. (2006) · Analytical Biochemistry · doi:10.1016/j.ab.2006.10.043 · Cited by 188

Gene-Z: a device for point of care genetic testing using a smartphone

Stedtfeld, R. D., Tourlousse, D. M., Seyrig, G., Stedtfeld, T. M., Kronlein, M. R., Price, S., Ahmad, F. J., Gülari, E., Tiedje, J. M., & Hashsham, S. A. (2012) · Lab on a Chip · doi:10.1039/c2lc21226a · Cited by 187

A smartphone platform for the quantification of vitamin D levels

Lee, S., Oncescu, V., Mancuso, M., Mehta, S., & Erickson, D. (2014) · Lab on a Chip · doi:10.1039/c3lc51375k · Cited by 185

Smartphone technology can be transformative to the deployment of lab-on-chip diagnostics

Erickson, D., O’Dell, D., Jiang, L., Oncescu, V., Gümüş, A., Lee, S., Mancuso, M., & Mehta, S. (2014) · Lab on a Chip · doi:10.1039/c4lc00142g · Cited by 183

Bacterial detection: From microscope to smartphone

Gopinath, S. C. B., Tang, T., Chen, Y., Citartan, M., & Lakshmipriya, T. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.04.014 · Cited by 167

IMIA Yearbook of Medical Informatics 2013

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Mobile cell-phones (M-phones) in telemicroscopy: increasing connectivity of isolated laboratories

Bellina, L., & Missoni, E. (2009) · Diagnostic Pathology · doi:10.1186/1746-1596-4-19 · Cited by 129

Disposable lateral flow-through strip for smartphone-camera to quantitatively detect alkaline phosphatase activity in milk

Yu, L. D., Shi, Z., Fang, C., Zhang, Y., Liu, Y., & Li, C. M. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.02.035 · Cited by 127

Mobile-platform based colorimeter for monitoring chlorine concentration in water

Sumriddetchkajorn, S., Chaitavon, K., & Intaravanne, Y. (2013) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2013.10.024 · Cited by 122

Using the iPhone as a device for a rapid quantitative analysis of trinitrotoluene in soil

Choodum, A., Kanatharana, P., Wongniramaikul, W., & Daéid, N. N. (2013) · Talanta · doi:10.1016/j.talanta.2013.04.037 · Cited by 117

Performance Improvement of the One-Dot Lateral Flow Immunoassay for Aflatoxin B1 by Using a Smartphone-Based Reading System

Lee, S., Kim, G., & Moon, J.-H. (2013) · Sensors · doi:10.3390/s130405109 · Cited by 114

Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array

Navruz, İ., Coskun, A. F., Wong, J., Mohammad, S., Tseng, D. K., Nagi, R., Phillips, S. W., & Özcan, A. (2013) · Lab on a Chip · doi:10.1039/c3lc50589h · Cited by 112

Smartphone-interfaced 3D printed toxicity biosensor integrating bioluminescent “sentinel cells”

Cevenini, L., Calabretta, M. M., Tarantino, G., Michelini, E., & Roda, A. (2015) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2015.11.017 · Cited by 110

Smartphone based bacterial detection using biofunctionalized fluorescent nanoparticles

Rajendran, V. K., Bakthavathsalam, P., & Ali, B. M. J. (2014) · Microchimica Acta · doi:10.1007/s00604-014-1242-5 · Cited by 102

Real-time measurement of human salivary cortisol for the assessment of psychological stress using a smartphone

Choi, S., Kim, S., Yang, J.-S., Lee, J., Joo, C., & Jung, H. (2014) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2014.08.001 · Cited by 93

Mobile phone-based electrochemiluminescence sensing exploiting the ‘USB On-The-Go’ protocol

Doeven, E. H., Barbante, G. J., Harsant, A. J., Donnelly, P. S., Connell, T. U., Hogan, C. F., & Francis, P. S. (2015) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2015.04.087 · Cited by 84

Development of a quantitative rapid diagnostic test for multibacillary leprosy using smart phone technology

Cardoso, L. P. V., Dias, R. F., Freitas, A. A., Hungria, E. M., Oliveira, R. M., Collovati, M., Reed, S. G., Duthie, M. S., & Stefani, M. M. A. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-497 · Cited by 84

Graphene-based rapid and highly-sensitive immunoassay for C-reactive protein using a smartphone-based colorimetric reader

Vashist, S. K., Schneider, E. M., Zengerle, R., von Stetten, F., & Luong, J. H. T. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.11.017 · Cited by 81

Bioengineered bioluminescent magnetotactic bacteria as a powerful tool for chip-based whole-cell biosensors

Roda, A., Cevenini, L., Borg, S., Michelini, E., Calabretta, M. M., & Schüler, D. (2013) · Lab on a Chip · doi:10.1039/c3lc50868d · Cited by 77

Surface Plasmon Resonance Chemical Sensing on Cell Phones

Preechaburana, P., Gonzalez, M. C., Suska, A., & Filippini, D. (2012) · Angewandte Chemie · doi:10.1002/ange.201206804 · Cited by 54

DNA detection using commercial mobile phones

Lee, D., Chou, W. P., Yeh, S.-H., Chen, P., & Chen, P. H. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2011.04.036 · Cited by 53

Development of a sensitive enzyme immunoassay for plasma and salivary steroids

Roda, A., Girotti, S., Lodi, S., & Preti, S. C. (1984) · Talanta · doi:10.1016/0039-9140(84)80218-0 · Cited by 34

Dioxetane-Doped Silica Nanoparticles as Ultrasensitive Reagentless Thermochemiluminescent Labels for Bioanalytics

Roda, A., Fusco, M. D., Quintavalla, A., Guardigli, M., Mirasoli, M., Lombardo, M., & Trombini, C. (2012) · Analytical Chemistry · doi:10.1021/ac302306u · Cited by 28

Cell Phones in Telehealth and Otolaryngology

Kenyon, J., Poropatich, R. K., & Holtel, M. R. (2011) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2011.08.013 · Cited by 16

The Optoelectronic Nose: Colorimetric and Fluorometric Sensor Arrays

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Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

Dincer, C., Bruch, R. C., Costa‐Rama, E., Fernández-Abedul, M. T., Merkoçi, A., Manz, A., Urban, G. A., & Güder, F. (2019) · Advanced Materials · doi:10.1002/adma.201806739 · Cited by 996

Point-of-care diagnostics for infectious diseases: From methods to devices

Wang, C., Liu, M., Wang, Z., Song, L., Deng, Y., & He, N. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101092 · Cited by 642

Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays

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Portable Spectroscopy

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Handbook of enzymatic methods of analysis

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Smartphone-Based Biosensors for Bioanalytics

Roda, A., Calabretta, M. M., Calabria, D., Caliceti, C., Cevenini, L., Lopreside, A., & Zangheri, M. (2017) · Comprehensive analytical chemistry · doi:10.1016/bs.coac.2017.05.007 · Cited by 17

Recent advancements of smartphone-based sensing technology for diagnosis, food safety analysis, and environmental monitoring

Upadhyay, S., Kumar, A., Srivastava, M., Srivastava, A., Dwivedi, A., Singh, R. K., & Srivastava, S. (2024) · Talanta · doi:10.1016/j.talanta.2024.126080 · Cited by 106

Smartphone-based analytical biosensors

Huang, X., Xu, D., Chen, J., Liu, J., Li, Y., Song, J. Y., Ma, X., & Guo, J. (2018) · The Analyst · doi:10.1039/c8an01269e · Cited by 308

Smartphone-based chemical sensors and biosensors for biomedical applications

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