The DOI matches its Crossref record; 66 of the 69 references it cites were found in a registry or an index.
Impact of ultrasound and conventional extraction techniques on bioactive compounds and biological activities of blue butterfly pea flower (Clitoria ternatea L.)
Open accessAbstract
The present study was conducted to evaluate the influence of ultrasound on bioactive compounds and biological activities of blue butterfly pea flower (Clitoria ternatea L.). For this purpose, optimized conditions (temperature 50 °C, time 150 min, solid to liquid ratio 1 g:15 ml, 70% amplitude and 240 W, 20 kHz frequency, 3 s on and 3 s off) of ultrasound (US) and conventional extraction (AGE: Agitation, water bath for 150 min, 50 °C at 150 rmp) were used. The results showed significant (p < 0.05) effect of US and AGE on total phenolics (TPCs), flavonoids (TFCs) and antioxidant activities (DPPH, ABTS, FRAP, reducing activity, Cu2+ and H2O2) of butterfly pea flower extract (BPFE). The results showed an increased trend in yield, TPCs, TFCs and antioxidant activities of US treated BPFE with comparison to AGE. However, insignificant (p > 0.05) effect of US and AGE over TFlaCs and PACs were observed. Moreover, the results of Fourier-transform infrared spectroscopy (FTIR) showed little changes in spectrum and US does not affect the functional group of bioactive compounds structure. Additionally, extracts (500–2000 µg/ml) protect pBR322 plasmid DNA damage induced by (1 mM H2O2 and 1 mM FeSO4), plasma oxidation (induced by 250 µM CuCl2) and inhibit erythrocyte hemolysis (induced by 200 mM AAPH, 34.6 to 66.73%). Sonication can be applied successfully for the extraction of bioactive compounds from plant materials with high biological activities.
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“Several studies have indicated that employing suitable ultrasonic conditions can not only enhance the content of phenolic compounds but also improve their antioxidant activity [38], [39].”
From A comprehensive review of ultrasonic assisted extraction (UAE) for bioactive components: Principles, advantages, equipment, and combined technologies (2023) · cites this paper as [38]
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Shen, L., Pang, S., Zhong, M., Sun, Y., Qayum, A., Liu, Y., Rashid, A., Xu, B., Liang, Q., Ma, H., et al. (2023) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2023.106646 · Cited by 892
“Several studies have indicated that employing suitable ultrasonic conditions can not only enhance the content of phenolic compounds but also improve their antioxidant activity [38,39].”
BackgroundFu, X., Belwal, T., Cravotto, G., & Luo, Z. (2019) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2019.104726 · Cited by 316
Combination of emerging technologies for the extraction of bioactive compounds
Wen, L., Zhang, Z., Sun, D., Saravana, P. S., & Tiwari, B. K. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1602823 · Cited by 313
“Conventional and novel extraction technologies have be applied for the extraction of bioactive compounds from various natural sources (Pimentel-Moral et al. 2018; Mehmood et al. 2019; Moreira et al. 2019; Peanparkdee and Iwamoto 2019; Sharayei et al. 2019).”
BackgroundRifna, E. J., Misra, N. N., & Dwivedi, M. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1952923 · Cited by 275
“In present times, few works have studied the pooling of enzyme-assisted and ultrasound-assisted extraction techniques, generally termed as ultrasound assisted enzymatic extraction (UAEE) for leaching out of phytochemicals (Mehmood et al. 2019).”
BackgroundFu, X., Wang, D., Belwal, T., Xu, Y., Li, L., & Luo, Z. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.129577 · Cited by 226
Metadata
- Authors
- Mehmood, A., Ishaq, M., Zhao, L., Yaqoob, S., Safdar, B., Nadeem, M., Munir, M., & Wang, C.
- Affiliations
- Beijing Technology and Business University (CN)
- Jilin Agricultural University (CN)
- University of Sargodha (PK)
- Corresponding author
- Zhao, Lei
- Munir, Masooma
- Wang, Chengtao
- ORCID
- Venue
- Ultrasonics Sonochemistry
- Publisher
- Elsevier BV
- Published
- 2019-03
- Volume
- 51
- Pages
- 12-19
- ISSN
- 1350-4177 (ISSN-L)
- OpenAlex
- W2896976712
- Cited by
- 184
- References
- 69
- Citations by year
- 2026: 17 · 2025: 18 · 2024: 37 · 2023: 37 · 2022: 24 · 2021: 20 · 2020: 19 · 2019: 11
- FWCI
- 8.77
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Ultrasonics Sonochemistry (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- Funders
- National key research and development program (2018YFD0400403, 2016YFD0400802)
- National Natural Science Foundation of China (31571801)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Physical Sciences › Physics and Astronomy › Acoustics and Ultrasonics › Ultrasound and Cavitation Phenomena
- Keywords
- ultrasound-assisted extraction, Clitoria ternatea, butterfly pea flower, bioactive compounds, total phenolic content, flavonoids, antioxidant activity, free radical scavenging, DNA protection, extraction optimization, plant extracts
- MeSH terms
- Ultrasonic Waves, Animals, Antioxidants, Erythrocytes, Chemical Fractionation, Hemolysis, Oxidation-Reduction, Phenols, Plant Extracts, Temperature, Xanthine Oxidase, Clitoria, Proanthocyanidins
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