Adherence to a low-fat diet in men with prostate cancer
Abstract
Objectives To evaluate, in a feasibility study, the adherence to a low-fat diet by men with prostate cancer. Evidence is growing that a low-fat diet affects the development and course of prostate cancer. To design preventive and therapeutic interventions, it is important to know whether men will adhere to these nutritional recommendations, particularly when motivated by the diagnosis of prostate cancer.Methods Men with elevated prostate-specific antigen levels, most of whom were recently treated for prostate cancer, were randomized to one of four dietary regimens for which they received nutritional counseling: a low-fat diet (15% fat or less) with supplements (vitamin E and selenium), a low-fat diet (15% fat or less) without the supplements, the supplements alone, and a control group. Adherence was evaluated by the change in weight, fat intake, free fatty acids, cholesterol, high-density and low-density lipoproteins, and triglycerides during a 12-month period.Results The mean age of the 48 participants was 66 years. For those counseled about a low-fat diet, the mean change in the percentage of energy (kilocalories) in the diet from fat was greater after 3 months (-8.6% versus +2.1%, P <0.001) and 12 months (-9.8% versus -1.6%, P = 0.001). Three months after starting the intervention, those randomized to low-fat dietary counseling had lost 2 kg, on average, compared with 0.8 kg lost by those who did not receive this counseling (P = 0.09). At 12 months, those receiving low-fat counseling had lost 2.8 kg, on average, compared with 0.5 kg gained among the other groups (P = 0.02).Conclusions With appropriate counseling, men with prostate cancer can adhere to a low-fat dietary intervention for a 12-month period.
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Dietary counseling was attributed to the success of individuals with other conditions on low-fat diets (<15% fat).
“Dietary counseling was attributed to the success of individuals with other conditions on low-fat diets (,15% fat), and dietary counseling enabled patients to better adhere to the low-fat dietary regimen.64”
From Familial chylomicronemia syndrome: Bringing to life dietary recommendations throughout the life span (2018) · cites this paper as [64]
Dietary counseling enabled patients to better adhere to the low-fat dietary regimen.
“Dietary counseling was attributed to the success of individuals with other conditions on low-fat diets (,15% fat), and dietary counseling enabled patients to better adhere to the low-fat dietary regimen.64”
From Familial chylomicronemia syndrome: Bringing to life dietary recommendations throughout the life span (2018) · cites this paper as [64]
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- Authors
- Link, L. B., Thompson, S. M., Bosland, M. C., & Lumey, L. H.
- Affiliations
- Columbia University (US)
- Institute for Cancer Prevention (US)
- New York University (US)
- Corresponding author
- Lumey, L.H.
- Venue
- Urology
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 64
- Issue
- 5
- Pages
- 970-975
- ISSN
- 0090-4295 (ISSN-L)
- OpenAlex
- W2065255672
- Cited by
- 15
- References
- 27
- Citations by year
- 2026: 1 · 2025: 1 · 2022: 1 · 2021: 1 · 2018: 2 · 2014: 2 · 2012: 1
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Urology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Lipids, and Metabolism
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Keywords
- prostate cancer, low-fat diet, dietary adherence, nutrition counseling, vitamin E, selenium supplements, weight loss, dietary fat intake, lipid profile, prostate-specific antigen, dietary intervention
- MeSH terms
- Aged, Body Weight, Cholesterol, Dietary Fats, Feasibility Studies, Humans, Male, Nutritional Requirements, Patient Compliance, Prostatic Neoplasms, Time Factors, United States, Prostate-Specific Antigen, Diet, Fat-Restricted, Dietary Supplements
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