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L-type Amino Acid Transporter 1 (SLC7A5)-Mediated Transport of Pregabalin at the Rat Blood-Spinal Cord Barrier and its Sensitivity to Plasma Branched-Chain Amino Acids

Akashi, Tomoya, Noguchi, Saki, Takahashi, Yu, Nishimura, Tomohiro, Tomi, Masatoshi·2023·Journal of Pharmaceutical Sciences
DOI 10.1016/j.xphs.2022.12.028
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  1. Colloca, 2017, Neuropathic pain, Nat Rev Dis Primers, 3, 1, 10.1038/nrdp.2017.2 · DOI
  2. Murphy, 2020, Peripheral neuropathic pain, NeuroRehabilitation, 47, 265
  3. Field, 2006, Identification of the α2-δ-1 subunit of voltage-calcium calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin, Proc Natl Acad Sci U S A, 103, 17537, 10.1073/pnas.0409066103 · DOI
  4. Chincholkar, 2018, Analgesic mechanisms of gabapentinoids and effects in experimental pain models: a narrative review, Br J Anaesth, 120, 1315, 10.1016/j.bja.2018.02.066 · DOI
  5. Vongveeranonchai, 2014, Evaluation of a patient with spinal cord infarction after a hypotensive episode, Stroke, 45, e203, 10.1161/STROKEAHA.114.006490 · DOI
  6. Uchida, 2020, Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and the blood-spinal cord barrier in humans and rats, Mol Pharm, 17, 2006, 10.1021/acs.molpharmaceut.0c00178 · DOI
  7. Uchida, 2019, Involvement of claudin-11 in disruption of blood-brain, -spinal cord, and -arachnoid barriers in multiple sclerosis, Mol Neurobiol, 56, 2039, 10.1007/s12035-018-1207-5 · DOI
  8. Benet, 2011, BDDCS Applied to over 900 drugs, AAPS J, 13, 519, 10.1208/s12248-011-9290-9 · DOI
  9. Su, 2005, Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells, J Pharmacol Exp Ther, 313, 1406, 10.1124/jpet.104.082255 · DOI
  10. Takahashi, 2018, Transport of pregabalin via L-type amino acid transporter 1 (SLC7A5) in human brain capillary endothelial cell line, Pharm Res, 35, 10.1007/s11095-018-2532-0 · DOI
  11. Toyooka, 2008, Up-regulation of L type amino acid transporter 1 after spinal cord injury in rats, Acta Neurochir Suppl (Wien), 385, 10.1007/978-3-211-85578-2_74 · DOI
  12. Lamhonwah, 2008, Expression patterns of the organic cation/carnitine transporter family in adult murine brain, Brain Dev, 30, 31, 10.1016/j.braindev.2007.05.005 · DOI
  13. Watson, 2013, Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier, BMC Neurosci, 14, 1, 10.1186/1471-2202-14-59 · DOI
  14. Noguchi, 2021, Substrate recognition of renally eliminated angiotensin II receptor blockers by organic anion transporter 4, Drug Metab Pharmacokinet, 36, 10.1016/j.dmpk.2020.10.002 · DOI
  15. Dhanikula, 2016, Evaluation of P-glycoprotein expression in pain relevant tissues: understanding translation of efflux from preclinical species to human, ADMET DMPK, 4, 261, 10.5599/admet.4.3.305 · DOI
  16. Oda, 2010, l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth, Cancer Sci, 101, 173, 10.1111/j.1349-7006.2009.01386.x · DOI
  17. Yanagida, 2001, Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines, Biochim Biophys Acta Biomembr, 1514, 291, 10.1016/S0005-2736(01)00384-4 · DOI · Paper page
  18. del Amo, 2008, Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2, Eur J Pharm Sci, 35, 161, 10.1016/j.ejps.2008.06.015 · DOI
  19. Berry, 2005, Analysis of pregabalin at therapeutic concentrations in human plasma/serum by reversed-phase HPLC, Ther Drug Monit, 27, 451, 10.1097/01.ftd.0000158874.54100.1a · DOI
  20. Takahashi, 2018, Transport of pregabalin via L-type amino acid transporter 1 (SLC7A5) in human brain capillary endothelial cell line, Pharm Res, 35, 246, 10.1007/s11095-018-2532-0 · DOI
  21. Blasberg, 1983, Transport of α-aminoisobutyric acid across brain capillary and cellular membranes, J Cereb Blood Flow Metab, 3, 8, 10.1038/jcbfm.1983.2 · DOI
  22. Otsuki, 2017, Prostate cancer cells in different androgen receptor status employ different leucine transporters, Prostate, 77, 222, 10.1002/pros.23263 · DOI
  23. Blum, 2021, Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons, Nat Neurosci, 24, 572, 10.1038/s41593-020-00795-0 · DOI · Paper page
  24. Fukushima, 2007, Oral branched-chain amino acid supplementation improves the oxidized/reduced albumin ratio in patients with liver cirrhosis, Hepatol Res, 37, 765, 10.1111/j.1872-034X.2007.00123.x · DOI
  25. Zhang, 2011, Effects of branched-chain amino acid supplementation on plasma concentrations of free amino acids, insulin, and energy substrates in young men, J Nutr Sci Vitaminol (Tokyo), 57, 114, 10.3177/jnsv.57.114 · DOI
  26. Adibi, 1973, Protein digestion in human intestine as reflected in luminal, mucosal, and plasma amino acid concentrations after meals, Journal of Clinical Investigation, 52, 1586, 10.1172/JCI107335 · DOI
  27. Kadota, 2012, Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats, J Parenter Enter Nutr, 36, 337, 10.1177/0148607111414578 · DOI
  28. Knapik-Czajka, 2009, Adverse effect of fenofibrate on branched-chain α-ketoacid dehydrogenase complex in rat's liver, Toxicology, 266, 1, 10.1016/j.tox.2009.10.002 · DOI
  29. Cucca, 2015, Amino acid supplementation in l-dopa treated Parkinson's disease patients, Clin Nutr, 34, 1189, 10.1016/j.clnu.2014.12.007 · DOI
  30. Leenders, 1986, Inhibition ofL-{18F}fluorodopa uptake into human brain by amino acids demonstrated by positron emission tomography, Ann Neurol, 20, 258, 10.1002/ana.410200212 · DOI
  31. Dickens, 2013, Transport of gabapentin by LAT1 (SLC7A5), Biochem Pharmacol, 85, 1672, 10.1016/j.bcp.2013.03.022 · DOI

Cited by

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Metadata

Authors
Akashi, T., Noguchi, S., Takahashi, Y., Nishimura, T., & Tomi, M.
ORCID
Venue
Journal of Pharmaceutical Sciences
Publisher
Elsevier BV
Published
2023-04
Volume
112
Issue
4
Pages
1137-1144
ISSN
0022-3549
DOI
10.1016/j.xphs.2022.12.028
Cited by
8
References
3
Language
en
Licence
Funders
Japan Society for the Promotion of Science (18H03183, 21H02651, 22K20723)

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