The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The structure of the nervous system of the nematode Caenorhabditis elegans
White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1986) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1986.0056 · Cited by 5,589
The Aryl Hydrocarbon Receptor Complex
Hankinson, O. (1995) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.35.040195.001515 · Cited by 1,649 · cited 1×
“The AHR–ARNT complex binds to specific DNA sequences to regulate the expression of target genes (Hankinson, 1995).”
BackgroundAH RECEPTOR SIGNALING PATHWAYS
Schmidt, J. V., & Bradfield, C. A. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.55 · Cited by 899
Lahvis, G. P., Lindell, S. L., Thomas, R. S., McCuskey, R. S., Murphy, C., Glover, E., Bentz, M., Southard, J., & Bradfield, C. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.190256997 · Cited by 377
Probst, M. R., Reisz-Porszasz, S., Agbunag, R. V., Ong, M. S., & Hankinson, O. (1993) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13218-5 · Cited by 214
Research works printed but not linked: 62
- Abbott, 1995, Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo, Dev. Dyn., 204, 133, 10.1002/aja.1002040204 · DOI · Paper page
- Altun-Gultekin, 2001, A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans, Development, 128, 1951, 10.1242/dev.128.11.1951 · DOI · Paper page
- Benedict, 2000, Physiological role of the aryl hydrocarbon receptor in mouse ovary development, Toxicol. Sci., 56, 382, 10.1093/toxsci/56.2.382 · DOI · Paper page
- Brenner, 1974, The genetics of Caenorhabditis elegans, Genetics, 77, 71, 10.1093/genetics/77.1.71 · DOI · Paper page
- Butler, 2001, An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding, Gene, 278, 223, 10.1016/S0378-1119(01)00724-7 · DOI · Paper page
- Carver, 1997, Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo, J. Biol. Chem., 272, 11452, 10.1074/jbc.272.17.11452 · DOI · Paper page
- Coates, 2002, Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans, Nature, 419, 925, 10.1038/nature01170 · DOI · Paper page
- Colavita, 1998, Pioneer axon guidance by UNC-129, a C. elegans TGF-beta, Science, 281, 706, 10.1126/science.281.5377.706 · DOI · Paper page
- Crews, 1999, Remembrance of things PAS: regulation of development by bHLH-PAS proteins, Curr. Opin. Genet. Dev., 9, 580, 10.1016/S0959-437X(99)00003-9 · DOI · Paper page
- de Bono, 1998, Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans, Cell, 94, 679, 10.1016/S0092-8674(00)81609-8 · DOI · Paper page
- de Bono, 2002, Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli, Nature, 419, 899, 10.1038/nature01169 · DOI · Paper page
- Denis, 1988, Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor, Biochem. Biophys. Res. Commun., 155, 801, 10.1016/S0006-291X(88)80566-7 · DOI · Paper page
- Dong, 2002, 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the zebrafish embryo: local circulation failure in the dorsal midbrain is associated with increased apoptosis, Toxicol. Sci., 69, 191, 10.1093/toxsci/69.1.191 · DOI · Paper page
- Duggan, 1998, Regulation of touch receptor differentiation by the Caenorhabditis elegans mec-3 and unc-86 genes, Development, 125, 4107, 10.1242/dev.125.20.4107 · DOI
- Duncan, 1998, Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor, Genes Dev., 12, 1290, 10.1101/gad.12.9.1290 · DOI · Paper page
- Emmons, 1999, The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila, Development, 126, 3937, 10.1242/dev.126.17.3937 · DOI
- Fernandez-Salguero, 1995, Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor, Science, 268, 722, 10.1126/science.7732381 · DOI · Paper page
- Finney, 1990, The unc-86 gene product couples cell lineage and cell identity in C. elegans, Cell, 63, 895, 10.1016/0092-8674(90)90493-X · DOI · Paper page
- Gu, 2000, The PAS superfamily: sensors of environmental and developmental signals, Annu. Rev. Pharmacol. Toxicol., 40, 519, 10.1146/annurev.pharmtox.40.1.519 · DOI · Paper page
- Hallam, 2000, The C. elegans NeuroD homolog cnd-1 functions in multiple aspects of motor neuron fate specification, Development, 127, 4239, 10.1242/dev.127.19.4239 · DOI
- Hao, 2001, C. elegans slit acts in midline, dorsal–ventral, and anterior–posterior guidance via the SAX-3/Robo receptor, Neuron, 32, 25, 10.1016/S0896-6273(01)00448-2 · DOI · Paper page
- Hays, 2002, Evidence that GABAergic neurons in the preoptic area of the rat brain are targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin during development, Environ. Health Perspect., 110, 369, 10.1289/ehp.02110s3369 · DOI
- Henshel, 1997, Brain asymmetry as a potential biomarker for developmental TCDD intoxication: a dose–response study, Environ. Health Perspect., 105, 718, 10.1289/ehp.97105718 · DOI
- Hodgkin, 1997, Natural variation and copulatory plug formation in Caenorhabditis elegans, Genetics, 146, 149, 10.1093/genetics/146.1.149 · DOI · Paper page
- Huang, 2002, MAX-1, a novel PH/MyTH4/FERM domain cytoplasmic protein implicated in netrin-mediated axon repulsion, Neuron, 34, 563, 10.1016/S0896-6273(02)00672-4 · DOI
- Huang, 2004, The AHR-1 aryl hydrocarbon receptor and its co-factor the AHA-1 aryl hydrocarbon receptor nuclear translocator specify GABAergic neuron cell fate in C. elegans, Development, 131, 819, 10.1242/dev.00959 · DOI
- Jain, 1998, Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse, Mech. Dev., 73, 117, 10.1016/S0925-4773(98)00038-0 · DOI · Paper page
- Jansen, 1997, Reverse genetics by chemical mutagenesis in Caenorhabditis elegans, Nat. Genet., 17, 119, 10.1038/ng0997-119 · DOI · Paper page
- Jiang, 2001, The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia, Proc. Natl. Acad. Sci. U. S. A., 98, 7916, 10.1073/pnas.141234698 · DOI · Paper page
- Jurata, 2000, Transcriptional mechanisms in the development of motor control, Curr. Opin. Neurobiol., 10, 72, 10.1016/S0959-4388(99)00053-7 · DOI
- Kim, 1999, SDQR migrations in Caenorhabditis elegans are controlled by multiple guidance cues and changing responses to netrin UNC-6, Development, 126, 3881, 10.1242/dev.126.17.3881 · doi:10.1242/dev.126.17.3881
- Ma, 1997, A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin, J. Biol. Chem., 272, 8878, 10.1074/jbc.272.14.8878 · DOI · Paper page
- Matikainen, 2001, Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals, Nat. Genet., 28, 355, 10.1038/ng575 · DOI · Paper page
- Mello, 1991, Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences, EMBO J., 10, 3959, 10.1002/j.1460-2075.1991.tb04966.x · DOI · Paper page
- Meyer, 2000, Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2, Cell Stress Chaperones, 5, 243, 10.1379/1466-1268(2000)005<0243:AHARLA>2.0.CO;2 · DOI
- Mimura, 1997, Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor, Genes Cells, 2, 645, 10.1046/j.1365-2443.1997.1490345.x · DOI · Paper page
- Patandin, 1999, Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 months of age, J. Pediatr., 134, 33, 10.1016/S0022-3476(99)70369-0 · DOI · Paper page
- Perdew, 1988, Association of the Ah receptor with the 90-kDa heat shock protein, J. Biol. Chem., 263, 13802, 10.1016/S0021-9258(18)68314-0 · DOI · Paper page
- Petersen, 2000, Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem, J. Comp. Neurol., 427, 428, 10.1002/1096-9861(20001120)427:3<428::AID-CNE9>3.0.CO;2-P · DOI
- Peterson, 1993, Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons, Crit. Rev. Toxicol., 23, 283, 10.3109/10408449309105013 · DOI · Paper page
- Powell-Coffman, 1998, Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator, Proc. Natl. Acad. Sci. U. S. A., 95, 2844, 10.1073/pnas.95.6.2844 · DOI · Paper page
- Reyes, 1992, Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor, Science, 256, 1193, 10.1126/science.256.5060.1193 · DOI · Paper page
- Rohrig, 2000, Protein interaction surface of the POU transcription factor UNC-86 selectively used in touch neurons, EMBO J., 19, 3694, 10.1093/emboj/19.14.3694 · doi:10.1093/emboj/19.14.3694
- Sarafi-Reinach, 2001, The lin-11 LIM homeobox gene specifies olfactory and chemosensory neuron fates in C. elegans, Development, 128, 3269, 10.1242/dev.128.17.3269 · DOI
- Schantz, 1989, Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), Neurotoxicol. Teratol., 11, 13, 10.1016/0892-0362(89)90080-9 · DOI · Paper page
- Schmidt, 1996, Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development, Proc. Natl. Acad. Sci. U. S. A., 93, 6731, 10.1073/pnas.93.13.6731 · DOI · Paper page
- Shimizu, 2000, Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor, Proc. Natl. Acad. Sci. U. S. A., 97, 779, 10.1073/pnas.97.2.779 · DOI · Paper page
- Shirasaki, 2002, Transcriptional codes and the control of neuronal identity, Annu. Rev. Neurosci., 25, 251, 10.1146/annurev.neuro.25.112701.142916 · DOI · Paper page
- Song, 2002, A ligand for the aryl hydrocarbon receptor isolated from lung, Proc. Natl. Acad. Sci. U. S. A., 99, 14694, 10.1073/pnas.232562899 · DOI · Paper page
- Sulston, 1977, Post-embryonic cell lineages of the nematode, Caenorhabditis elegans, Dev. Biol., 56, 110, 10.1016/0012-1606(77)90158-0 · DOI · Paper page
- Tam, 2000, Voltage-gated calcium channels direct neuronal migration in Caenorhabditis elegans, Dev. Biol., 226, 104, 10.1006/dbio.2000.9854 · DOI
- Vorderstrasse, 2001, Aryl hydrocarbon receptor-deficient mice generate normal immune responses to model antigens and are resistant to TCDD-induced immune suppression, Toxicol. Appl. Pharmacol., 171, 157, 10.1006/taap.2000.9122 · DOI · Paper page
- Ward, 1998, Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis, Development, 125, 1599, 10.1242/dev.125.9.1599 · doi:10.1242/dev.125.9.1599
- Way, 1988, mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans, Cell, 54, 5, 10.1016/0092-8674(88)90174-2 · DOI · Paper page
- Weinshenker, 1999, Block of an ether-a-go-go-like K(+) channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans, J. Neurosci., 19, 9831, 10.1523/JNEUROSCI.19-22-09831.1999 · doi:10.1523/jneurosci.19-22-09831.1999
- Whitlock, 1999, Induction of cytochrome P4501A1, Annu. Rev. Pharmacol. Toxicol., 39, 103, 10.1146/annurev.pharmtox.39.1.103 · DOI · Paper page
- Wu, 2001, Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans, Genes Dev., 15, 789, 10.1101/gad.857401 · DOI
- Xue, 1993, Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3, Science, 261, 1324, 10.1126/science.8103239 · DOI · Paper page
- Yu, 1997, Guanylyl cyclase expression in specific sensory neurons: a new family of chemosensory receptors, Proc. Natl. Acad. Sci. U. S. A., 94, 3384, 10.1073/pnas.94.7.3384 · DOI · Paper page
- Yu, 2002, Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function, Nat. Neurosci., 5, 1147, 10.1038/nn956 · DOI
- Zallen, 1998, The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans, Cell, 92, 217, 10.1016/S0092-8674(00)80916-2 · DOI · Paper page
- Zhang, 2002, Identification of genes expressed in C. elegans touch receptor neurons, Nature, 418, 331, 10.1038/nature00891 · DOI · Paper page
Cited by
The Genome of the Sea Urchin Strongylocentrotus purpuratus
Sodergren, E., Weinstock, G. M., Davidson, E. H., Cameron, R. A., Gibbs, R. A., Angerer, R. C., Angerer, L. M., Arnone, M. I., Burgess, D. R., Burke, R. D., et al. (2006) · Science · doi:10.1126/science.1133609 · Cited by 1,132
The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor
Nguyen, L. P., & Bradfield, C. A. (2008) · Chemical Research in Toxicology · doi:10.1021/tx7001965 · Cited by 709
The aryl hydrocarbon receptor, more than a xenobiotic‐interacting protein
Barouki, R., Coumoul, X., & Fernandez-Salguero, P. M. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.03.046 · Cited by 398
A cellular and regulatory map of the cholinergic nervous system of C. elegans
Pereira, L., Kratsios, P., Serrano-Saiz, E., Sheftel, H., Mayo, A. E., Hall, D. H., White, J. G., LeBoeuf, B., Garcia, L. R., Alon, U., et al. (2015) · eLife · doi:10.7554/elife.12432 · Cited by 365
Goldstone, J. V., Hamdoun, A., Cole, B. J., Howard-Ashby, M., Nebert, D. W., Scally, M., Dean, M., Epel, D., Hahn, M. E., & Stegeman, J. J. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.08.066 · Cited by 280
Metadata
- Authors
- Qin, H., & Powell-Coffman, J. A.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2004-06
- Volume
- 270
- Issue
- 1
- Pages
- 64-75
- ISSN
- 0012-1606 (ISSN-L)
- OpenAlex
- W2090922420
- Cited by
- 178
- References
- 5
- FWCI
- 2.19
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 3369 d)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development. https://app.cochat.ai/papers/10.1016/j.ydbio.2004.02.004
- The paper
- Qin, H., & Powell-Coffman, J. A. (2004). The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development. Developmental Biology. https://doi.org/10.1016/j.ydbio.2004.02.004
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.