The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Oocyte control of metabolic cooperativity between oocytes and companion granulosa cells: energy metabolism
Open accessAbstract
Intercellular communication between oocytes and granulosa cells is essential for normal follicular differentiation and oocyte development. Subtraction hybridization was used to identify genes more highly expressed in cumulus cells than in mural granulosa cells of mouse antral follicles. This screen identified six genes involved in glycolysis: Eno1, Pkm2, Tpi, Aldoa, Ldh1, and Pfkp. When oocytes were microsurgically removed from cumulus cell-oocyte complexes, the isolated cumulus cells exhibited decreased expression levels of genes encoding glycolytic enzymes, glycolysis and activity of the tricarboxylic acid (TCA) cycle. These decreases were prevented by culturing the cumulus cells with paracrine factors secreted by fully grown oocytes. Paracrine factors from fully grown oocytes exhibited greater ability than those from growing oocytes to promote expression of genes encoding glycolytic enzymes and glycolysis in the granulosa cells of preantral follicles. However, neither fully grown nor growing oocytes secreted paracrine factors affecting activity of the TCA cycle. These results indicate that oocytes regulate glycolysis and the TCA cycle in granulosa cells in a manner specific to the population of granulosa cells and to the stage of growth and development of the oocyte. Oocytes control glycolysis in granulosa cells by regulating expression levels of genes encoding glycolytic enzymes. Therefore, mouse oocytes control the intercellular metabolic cooperativity between cumulus cells and oocytes needed for energy production by granulosa cells and required for oocyte and follicular development.
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Cites
Oocyte control of ovarian follicular development and function in mammals
Eppig, J. J. (2001) · Reproduction · doi:10.1530/rep.0.1220829 · Cited by 1,021
Self-citationIntercellular Communication in the Mammalian Ovary: Oocytes Carry the Conversation
Matzuk, M. M., Burns, K. H., Viveiros, M. M., & Eppig, J. J. (2002) · Science · doi:10.1126/science.1071965 · Cited by 949
Self-citationThe pattern of energy metabolism in the mouse oöcyte and zygote.
Biggers, J. D., Whittingham, D. G., & Donahue, R. P. (1967) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.58.2.560 · Cited by 697
Paracrine Actions Of Growth Differentiation Factor-9 in the Mammalian Ovary
Elvin, J. A., Clark, A. T., Wang, P., Wolfman, N. M., & Matzuk, M. M. (1999) · Molecular Endocrinology · doi:10.1210/me.13.6.1035 · Cited by 651
Eppig, J. J., & Schroeder, A. C. (1989) · Biology of Reproduction · doi:10.1095/biolreprod41.2.268 · Cited by 603
Self-citationGrowth factors can influence cell growth and survival through effects on glucose metabolism
Vander Heiden, M. G., Plas, D. R., Rathmell, J. C., Fox, C. J., Harris, M. H., & Thompson, C. B. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5899-5912.2001 · Cited by 536
Interactions between Somatic Cells and Germ Cells Throughout Mammalian Oogenesis1
Buccione, R., Schroeder, A. C., & Eppig, J. J. (1990) · Biology of Reproduction · doi:10.1095/biolreprod43.4.543 · Cited by 505
Self-citationNutrient Requirements for the Culture of Preimplantation Embryos in Vitro
Whitten, W. K. (1971) · Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, Venice, April 20 to 23, 1970 · doi:10.1016/b978-0-08-017571-3.50013-9 · Cited by 503
The mammalian oocyte orchestrates the rate of ovarian follicular development
Eppig, J. J., Wigglesworth, K., & Pendola, F. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052658699 · Cited by 499
Self-citationIntercommunication between mammalian oocytes and companion somatic cells
Eppig, J. J. (1991) · BioEssays · doi:10.1002/bies.950131105 · Cited by 456
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Cited by
Physical properties of alginate hydrogels and their effects on in vitro follicle development
West, E. R., Xu, M., Woodruff, T. K., & Shea, L. D. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.001 · Cited by 371
Richani, D., Dunning, K. R., Thompson, J. G., & Gilchrist, R. B. (2021) · Human Reproduction Update · doi:10.1093/humupd/dmaa043 · Cited by 346
Regulation of folliculogenesis and the determination of ovulation rate in ruminants
Scaramuzzi, R. J., Baird, D. T., Campbell, B. K., Driancourt, M.-A., Dupont, J., Fortune, J. E., Gilchrist, R. B., Martin, G. B., McNatty, K. P., McNeilly, A. S., et al. (2011) · Reproduction, Fertility and Development · doi:10.1071/rd09161 · Cited by 310
PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update
Makker, A., Goel, M. M., & Mahdi, A. A. (2014) · Journal of Molecular Endocrinology · doi:10.1530/jme-14-0220 · Cited by 214
Jiang, C., Diao, F., Sang, Y.-J., Xu, N., Zhu, R.-L., Wang, X.-X., Chen, Z., Tao, W.-W., Yao, B., Sun, H.-X., et al. (2017) · PLOS Genetics · doi:10.1371/journal.pgen.1006535 · Cited by 39
Metadata
- Authors
- Sugiura, K., Pendola, F. L., & Eppig, J. J.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 279
- Issue
- 1
- Pages
- 20-30
- ISSN
- 0012-1606 (ISSN-L)
- OpenAlex
- W2076853816
- Cited by
- 391
- References
- 17
- FWCI
- 7.02
- Type
- journal article
- Language
- en
- Open access
- bronze
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