MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation
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miR-302 regulates neural progenitor proliferation, differentiation timing, and survival during neurulation; knockout results in early embryonic lethality and open neural tube defects.
“For example, miR-302, which we have found to be highly enriched in exosomes, has been shown to regulate neural progenitor proliferation, differentiation timing, and survival during neurulation, and knockout or miR-302 results in early embryonic lethality and open neural tube defects [28].”
From Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes (2017) · cites this paper as [28]
The Abstract reports that deletion of the miR-302/367 cluster caused early embryonic lethality and open neural tube defects, with altered neural progenitor proliferation, differentiation, and survival. The Discussion clarifies that this study deleted both miR-302 and miR-367, so its knockout and cell-survival findings cannot be attributed to miR-302 alone. (LLM, conf=0.88)
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Cites
Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability
Miska, E. A., Alvarez-Saavedra, E., Abbott, A. L., Lau, N. C., Hellman, A. B., McGonagle, S. M., Bartel, D. P., Ambros, V. R., & Horvitz, H. R. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030215 · Cited by 484 · cited 2× · see citing works
“elegans miRNAs are not essential for development and viability (AlvarezSaavedra and Horvitz, 2010; Miska et al., 2007).”
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Research works printed but not linked: 48
- Alvarez-Saavedra E Horvitz HR 2010 Many families of C. elegans microRNAs are not essential for development or viability Curr Biol 20 367 373 20096582 PMC2844791
- Bachler M Neubüser A 2001 Expression of members of the Fgf family and their receptors during midfacial development Mech Dev 100 313 316 11165488
- Bartel DP 2009 MicroRNAs: target recognition and regulatory functions Cell 136 215 233 19167326 PMC3794896
- Bernstein E Kim SY Carmell MA Murchison EP Alcorn H Li MZ Mills AA Elledge SJ Anderson KV Hannon GJ 2003 Dicer is essential for mouse development Nat Genet 35 215 217 14528307
- Borello U Cobos I Long JE McWhirter JR Murre C Rubenstein JLR 2008 FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development Neural Dev 3 17 18625063 PMC2492847
- Briscoe J Pierani A Jessell TM Ericson J 2000 A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube Cell 101 435 445 10830170
- Card DAG Hebbar PB Li L Trotter KW Komatsu Y Mishina Y Archer TK 2008 Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells Mol Cell Biol 28 6426 6438 18710938 PMC2577422
- Chang HM Martinez NJ Thornton JE Hagan JP Nguyen KD Gregory RI 2012 Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation Nat Commun 3 923 22735451 PMC3518406
- Chen J Lai F Niswander L 2012 The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling Genes & Development 26 803 815 22508726 PMC3337455
- Copp AJ 1995 Death before birth: clues from gene knockouts and mutations Trends Genet 11 87 93 7732578
- Copp AJ 2005 Neurulation in the cranial region--normal and abnormal J Anat 207 623 635 16313396 PMC1571567
- Crossley PH Martin GR 1995 The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo Development 121 439 451 7768185
- Ebert MS Sharp PA 2012 Roles for microRNAs in conferring robustness to biological processes Cell 149 515 524 22541426 PMC3351105
- Fox DT Peifer M 2007 Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila Development 134 567 578 17202187
- Greene NDE Copp AJ 2014 Neural tube defects Annu Rev Neurosci 37 221 242 25032496 PMC4486472
- Guo H Ingolia NT Weissman JS Bartel DP 2010 Mammalian microRNAs predominantly act to decrease target mRNA levels Nature 466 835 840 20703300 PMC2990499
- Haigo SL Hildebrand JD Harland RM Wallingford JB 2003 Shroom induces apical constriction and is required for hingepoint formation during neural tube closure Curr Biol 13 2125 2137 14680628
- Harris MJ Juriloff DM 2010 An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure Birth Defects Res Part A Clin Mol Teratol 88 653 669 20740593
- Ishibashi M Ang SL Shiota K Nakanishi S Kageyama R Guillemot F 1995 Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects Genes & Development 9 3136 3148 8543157
- Jamshidi-Adegani F Langroudi L Shafiee A Mohammadi-Sangcheshmeh A Ardeshirylajimi A Barzegar M Azadmanesh K Naderi M Arefian E Soleimani M 2014 Mir-302 cluster exhibits tumor suppressor properties on human unrestricted somatic stem cells Tumour Biol 35 6657 6664 24705778
- Jessell TM Dodd J 1990 Floor plate-derived signals and the control of neural cell pattern in vertebrates Harvey Lect 86 87 128 2152141
- Kim TH Goodman J Anderson KV Niswander L 2007 Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression Dev Cell 13 87 102 17609112
- Kuan CY Roth KA Flavell RA Rakic P 2000 Mechanisms of programmed cell death in the developing brain Trends in Neurosciences 23 291 297 10856938
- Lange C Huttner WB Calegari F 2009 Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors Cell Stem Cell 5 320 331 19733543
- Lardelli M Williams R Mitsiadis T Lendahl U 1996 Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development Mech Dev 59 177 190 8951795
- Leung AKL Sharp PA 2010 MicroRNA functions in stress responses Molecular Cell 40 205 215 20965416 PMC2996264
- Massagué J 2004 G1 cell-cycle control and cancer Nature 432 298 306 15549091
- Massarwa R Ray HJ Niswander L 2014 Morphogenetic movements in the neural plate and neural tube: mouse Wiley Interdiscip Rev Dev Biol 3 59 68 24902834
- Mendell JT Olson EN 2012 MicroRNAs in stress signaling and human disease Cell 148 1172 1187 22424228 PMC3308137
- Morita S Horii T Kimura M Goto Y Ochiya T Hatada I 2007 One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation Genomics 89 687 696 17418524
- Murdoch JN Copp AJ 2010 The relationship between sonic Hedgehog signaling, cilia, and neural tube defects Birth Defects Res Part A Clin Mol Teratol 88 633 652 20544799 PMC3635124
- Parchem RJ Moore N Fish JL Parchem JG Braga TT Shenoy A Oldham MC Rubenstein JLR Schneider RA Blelloch R 2015 miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability Cell Rep 12 760 773 26212322 PMC4741278
- Parchem RJ Ye J Judson RL LaRussa MF Krishnakumar R Blelloch A Oldham MC Blelloch R 2014 Two miRNA clusters reveal alternative paths in late-stage reprogramming Cell Stem Cell 14 617 631 24630794 PMC4305531
- Park CY Choi YS McManus MT 2010 Analysis of microRNA knockouts in mice Hum Mol Genet 19 R169 75 20805106 PMC2981466
- Pernaute B Spruce T Smith KM Sánchez-Nieto JM Manzanares M Cobb B Rodríguez TA 2014 MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM Genes & Development 28 1873 1878 25184675 PMC4197944
- Pfaff SL Mendelsohn M Stewart CL Edlund T Jessell TM 1996 Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation Cell 84 309 320 8565076
- Roffers-Agarwal J Xanthos JB Kragtorp KA Miller JR 2008 Enabled (Xena) regulates neural plate morphogenesis, apical constriction, and cellular adhesion required for neural tube closure in Xenopus Developmental Biology 314 393 403 18201691 PMC2266839
- Rosa A Spagnoli FM Brivanlou AH 2009 The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection Dev Cell 16 517 527 19386261
- Varga BV Hádinger N Gócza E Dulberg V Demeter K Madarász E Herberth B 2008 Generation of diverse neuronal subtypes in cloned populations of stem-like cells BMC Dev Biol 8 89 18808670 PMC2556672
- Vidigal JA Ventura A 2015 The biological functions of miRNAs: lessons from in vivo studies Trends Cell Biol 25 137 147 25484347 PMC4344861
- Wallingford JB 2012 Planar cell polarity and the developmental control of cell behavior in vertebrate embryos Annu Rev Cell Dev Biol 28 627 653 22905955
- Wang L Yao J Shi X Hu L Li Z Song T Huang C 2013 MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells BMC Cancer 13 448 24083596 PMC3850949
- Wang Y Baskerville S Shenoy A Babiarz JE Baehner L Blelloch R 2008 Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation Nat Genet 40 1478 1483 18978791 PMC2630798
- Wang Y Medvid R Melton C Jaenisch R Blelloch R 2007 DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal Nat Genet 39 380 385 17259983 PMC3008549
- Wilde JJ Petersen JR Niswander L 2014 Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure Annu Rev Genet 48 141007180313005 PMC4649936 25292356
- Yan G-J Yu F Wang B Zhou H-J Ge Q-Y Su J Hu Y-L Sun H-X Ding L-J 2014 MicroRNA miR-302 inhibits the tumorigenicity of endometrial cancer cells by suppression of Cyclin D1 and CDK1 Cancer Lett 345 39 47 24333727
- Yang M Yang SL Herrlinger S Liang C Dzieciatkowska M Hansen KC Desai R Nagy A Niswander L Moss EG 2015 Lin28 promotes the proliferative capacity of neural progenitor cells in brain development Development 142 1616 1627 25922525 PMC4419280
- Zhong W Jiang MM Schonemann MD Meneses JJ Pedersen RA Jan LY Jan YN 2000 Mouse numb is an essential gene involved in cortical neurogenesis Proc Natl Acad Sci USA 97 6844 6849 10841580 PMC18761
Cited by
Sorted by citations
Jovičić, A., & Gitler, A. D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0171418 · Cited by 86 · see citing works
- Authors
- Yang, S.-L., Yang, M., Herrlinger, S., Liang, C., Lai, F., & Chen, J.-F.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 408
- Issue
- 1
- Pages
- 140-150
- ISSN
- 0012-1606
- PMC
- PMC4688151
- Cited by
- 42
- References
- 1
- Language
- en
- Licence
- Funders
- NICHD (5R00HD073269)
- University of Georgia start up fund
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