Role of the hypothalamic–pituitary–adrenal axis in developmental programming of health and disease

Prenatal Excess Glucocorticoid Exposure and Adult Affective Disorders: A Role for Serotonergic and Catecholamine Pathways

Wyrwoll, C. S., & Holmes, M. C. (2011) · Neuroendocrinology · doi:10.1159/000331345 · Cited by 118

Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3

Kang, K. A., Zhang, R., Kim, G., Bae, S. C., & Hyun, J. W. (2012) · Tumor Biology · doi:10.1007/s13277-012-0322-6 · Cited by 117

Corticotropin-releasing hormone during pregnancy is associated with infant temperament

Davis, E. P., Glynn, L. M., Dunkel Schetter, C., Hobel, C., Chicz-Demet, A., & Sandman, C. A. (2005) · Developmental Neuroscience · doi:10.1159/000086709 · Cited by 116

Early postnatal leptin blockage leads to a long-term leptin resistance and susceptibility to diet-induced obesity in rats

Attig, L., Solomon, G., Férézou, J., Abdennebi‐Najar, L., Taouis, M., Gertler, A., & Djiane, J. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.39 · Cited by 115

Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis

Stewart, P. M. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.80.3.885 · Cited by 115

Prenatal exposure to dexamethasone alters hippocampal drive on hypothalamic-pituitary-adrenal axis activity in adult male rats

Shoener, J. A., Baig, R., & Page, K. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00757.2004 · Cited by 113

Long-term effects of intrauterine growth restriction on cardiac metabolism and susceptibility to ischaemia/reperfusion

Rueda‐Clausen, C. F., Morton, J. S., Lopaschuk, G. D., & Davidge, S. T. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq363 · Cited by 113

Prenatal stress induces body weight deficit and behavioural alterations in rats: the effect of diazepam

Drago, F., Leo, F., & Giardina, L. (1999) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(98)00032-7 · Cited by 111

Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A

Burgueño, A. L., Cabrerizo, R., Mansilla, N. G., Sookoian, S. C., & Pirola, C. J. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.12.008 · Cited by 110

Fetal Programming of Adipose Tissue: Effects of Intrauterine Growth Restriction and Maternal Obesity/High-Fat Diet

Desai, M., & Ross, M. (2011) · Seminars in Reproductive Medicine · doi:10.1055/s-0031-1275517 · Cited by 109

Oxygen Regulation of Placental 11β-Hydroxysteroid Dehydrogenase 2: Physiological and Pathological Implications

Alfaidy, N., Gupta, S., Demarco, C., Caniggia, I., & Challis, J. R. G. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020310 · Cited by 109

Prenatal programming of adult blood pressure: role of maternal corticosteroids

Woods, L. L., & Weeks, D. A. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00455.2004 · Cited by 108

Prenatal Stress Diminishes the Cytokine Response of Leukocytes to Endotoxin Stimulation in Juvenile Rhesus Monkeys

Coe, C. L., Kramer, M., Kirschbaum, C., Netter, P., & Fuchs, E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8233 · Cited by 108

Preterm newborn lamb renal and cardiovascular responses after fetal or maternal antenatal betamethasone

Berry, L. M., Polk, D. H., Ikegami, M., Jobe, A. H., Padbury, J. F., & Ervin, M. G. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.6.r1972 · Cited by 108

Zinc restriction during different periods of life: Influence in renal and cardiovascular diseases

Tomat, A. L., Costa, M. A., & Arranz, C. T. (2010) · Nutrition · doi:10.1016/j.nut.2010.09.010 · Cited by 105

Abnormal aortic fatty acid composition and small artery function in offspring of rats fed a high fat diet in pregnancy

Ghosh, P., Bitsanis, D., Ghebremeskel, K., Crawford, M. A., & Poston, L. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00815.x · Cited by 105

Highly individual methylation patterns of alternative glucocorticoid receptor promoters suggest individualized epigenetic regulatory mechanisms

Turner, J. D., Pelascini, L. P. L., Macedo, J. A., & Muller, C. P. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn897 · Cited by 104

Low Birth Weight Infants and the Developmental Programming of Hypertension: A Focus on Vascular Factors

Ligi, I., Grandvuillemin, I., Andrés, V., Dignat‐George, F., & Siméoni, U. (2010) · Seminars in Perinatology · doi:10.1053/j.semperi.2010.02.002 · Cited by 103

Review: Leptin gene expression in the placenta – Regulation of a key hormone in trophoblast proliferation and survival

Maymó, J. L., Pérez‐Pérez, A., Gambino, Y. P., Calvo, J. C., Sánchez‐Margalet, V., & Varone, C. L. (2011) · Placenta · doi:10.1016/j.placenta.2011.01.004 · Cited by 102

Detrimental effects of glucocorticoids on neuronal migration during brain development

Fukumoto, K., Morita, T., Mayanagi, T., Tanokashira, D., Yoshida, T., Sakai, A., & Sobue, K. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.60 · Cited by 102

Potentiation of Glucocorticoid Activity in Hypoxia through Induction of the Glucocorticoid Receptor

Leonard, M. O., Godson, C., Brady, H. R., & Taylor, C. T. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.4.2250 · Cited by 100

Tissue specific glucocorticoid receptor expression, a role for alternative first exon usage?

Turner, J. D., Schote, A. B., Macedo, J. A., Pelascini, L. P. L., & Muller, C. P. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.07.005 · Cited by 99

Dynamic changes in glucocorticoid and mineralocorticoid receptor mRNA in the developing guinea pig brain

Matthews, S. G. (1998) · Developmental Brain Research · doi:10.1016/s0165-3806(98)00008-x · Cited by 99

Developmental Programming of Renal Glucocorticoid Sensitivity and the Renin-Angiotensin System

Wyrwoll, C. S., Mark, P. J., & Waddell, B. J. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.091603 · Cited by 99

Multidrug Resistance Phosphoglycoprotein (ABCB1) in the Mouse Placenta: Fetal Protection1

Kalabis, G. M., Kostaki, A., Andrews, M. H., Sophie Petropoulos, A., Gibb, W., & Matthews, S. G. (2005) · Biology of Reproduction · doi:10.1095/biolreprod.105.042242 · Cited by 99

Inhibition of placental 11β-hydroxysteroid dehydrogenase type 2 by catecholamines via α-adrenergic signaling

Sarkar, S., Tsai, S., Nguyen, T. T., Plevyak, M. P., Padbury, J. F., & Rubin, L. P. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.281.6.r1966 · Cited by 99

Pharmacologic Enhancement of Fetal Lung Maturation

Ward, R. M. (1994) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30330-0 · Cited by 98

Ontogeny of hippocampal corticosteroid receptors: Effects of antenatal glucocorticoids in human and mouse

Noorlander, C. W., Graan, P. N. E. D., Middeldorp, J., van Beers, J. J. B. C., & Visser, G. H. A. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21162 · Cited by 98

Relation of Immediate Postnatal Growth With Obesity and Related Metabolic Risk Factors in Adulthood: The Northern Finland Birth Cohort 1966 Study

Tzoulaki, I., Sovio, U., Pillas, D., Hartikainen, A., Pouta, A. M., Laitinen, J. H., Tammelin, T., Järvelin, M., & Elliott, P. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq027 · Cited by 98

Positive regulation of the glucocorticoid receptor in human T-cells sensitive to the cytolytic effects of glucocorticoids.

Eisen, L. P., Elsasser, M. S., & Harmon, J. M. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)37890-6 · Cited by 97

Antenatal glucocorticoids and growth: single versus multiple doses in animal and human studies

Newnham, J. P., & Moss, T. J. M. (2001) · Seminars in Neonatology · doi:10.1053/siny.2001.0064 · Cited by 97

Prenatal dexamethasone programs expression of genes in liver and adipose tissue and increased hepatic lipid accumulation but not obesity on a high-fat diet

Drake, A. J., Raubenheimer, P. J., Kerrigan, D., McInnes, K. J., Seckl, J. R., & Walker, B. R. (2010) · Endocrinology · doi:10.1210/en.2009-1088 · Cited by 97

Effects into adulthood of single or repeated antenatal corticosteroids in sheep

Moss, T. J. M., Doherty, D. A., Nitsos, I., Sloboda, D. M., Harding, R., & Newnham, J. P. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.06.065 · Cited by 95

Stress experienced in utero reduces sexual dichotomies in neurogenesis, microenvironment, and cell death in the adult rat hippocampus

Mandyam, C. D., Crawford, E. F., Eisch, A. J., RIVIER, C. L., & Richardson, H. N. (2008) · Developmental Neurobiology · doi:10.1002/dneu.20600 · Cited by 93

Identification, tissue expression, and glucocorticoid responsiveness of alternative first exons of the human glucocorticoid receptor

Presul, E., Schmidt, S. U., Kofler, R., & Helmberg, A. (2007) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.02183 · Cited by 93

Hypoxia-derived oxidative stress mediates epigenetic repression of PKCɛ gene in foetal rat hearts

Patterson, A. J., Xiao, D., Xiong, F., Dixon, B., & Zhang, L. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr322 · Cited by 93

Differential timing for programming of glucose homoeostasis, sensitivity to insulin and blood pressure by in utero exposure to dexamethasone in sheep

Gatford, K. L., Wintour, E. M., Blasio, M. J. D., Owens, J. A., & Dodic, M. (2000) · Clinical Science · doi:10.1042/cs0980553 · Cited by 88

Prenatal Development of Glucocorticoid Receptor Gene Expression and Immunoreactivity in the Rat Brain and Pituitary Gland: A Combined in situ Hybridization and Immunocytochemical Analysis

Cintra, A., Solfrini, V., Bunnemann, B., Okret, S., Bortolotti, F., Gustafsson, J.-Å., & Fuxé, K. (2008) · Neuroendocrinology · doi:10.1159/000126480 · Cited by 88

Psychosocial maternal stress during pregnancy affects serum corticosterone, blood immune parameters and anxiety behaviour in adult male rat offspring

Götz, A. A., & Stefanski, V. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.09.014 · Cited by 87

Repeated prenatal corticosteroid administration delays astrocyte and capillary tight junction maturation in fetal sheep

Huang, W.-L., Harper, C., Evans, S., Newnham, J., & Dunlop, S. (2001) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(01)00035-1 · Cited by 85

Leptin Receptor Expression in the Rat Placenta: Changes in Ob-Ra, Ob-Rb, and Ob-Re with Gestational Age and Suppression by Glucocorticoids1

Smith, J. T., & Waddell, B. J. (2002) · Biology of Reproduction · doi:10.1095/biolreprod67.4.1204 · Cited by 85

Body Size at Birth Predicts Hypothalamic-Pituitary-Adrenal Axis Response to Psychosocial Stress at Age 60 to 70 Years

Kajantie, E., Feldt, K., Räikkönen, K., Phillips, D. I. W., Osmond, C., Heinonen, K., Pesonen, A., Andersson, S., Barker, D. J. P., & Eriksson, J. G. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1539 · Cited by 82

Course of placental 11beta-hydroxysteroid dehydrogenase type 2 and 15-hydroxyprostaglandin dehydrogenase mRNA expression during human gestation

Schoof, E., Girstl, M., Frobenius, W., Kirschbaum, M., Repp, R., Knerr, I., Rascher, W., & Dötsch, J. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1450187 · Cited by 81

Prodeath or prosurvival: Two facets of hypoxia inducible factor-1 in perinatal brain injury

Chen, W., Ostrowski, R. P., Obenaus, A., & Zhang, J. H. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.10.016 · Cited by 80

Glucocorticoid-Induced Fetal Programming Alters the Functional Complement of Angiotensin Receptor Subtypes Within the Kidney

Gwathmey, T. M., Shaltout, H. A., Rose, J. C., Diz, D. I., & Chappell, M. C. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.164970 · Cited by 80

Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats

Tong, W., Qin, X. Y., Li, Y., & Zhang, L. (2011) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00356.2011 · Cited by 79

Characterization of the Human Glucocorticoid Receptor Promoter

Nobukuni, Y., Smith, C. L., Hager, G. L., & Detera‐Wadleigh, S. D. (1995) · Biochemistry · doi:10.1021/bi00025a028 · Cited by 78

Brain Injury Caused by Chronic Fetal Hypoxemia Is Mediated by Inflammatory Cascade Activation

Guo, R., Hou, W., Dong, Y., Yu, Z., Stites, J., & Weiner, C. P. (2010) · Reproductive Sciences · doi:10.1177/1933719110364061 · Cited by 78

Mechanisms Underlying the Programming of Small Artery Dysfunction: Review of the Model Using Low Protein Diet in Pregnancy in the Rat

Brawley, L., Poston, L., & Hanson, M. A. (2003) · Archives of Physiology and Biochemistry · doi:10.1076/apab.111.1.23.15138 · Cited by 78

Fetal programming of atherosclerosis: Possible role of the mitochondria

Leduc, L., Levy, E. H., Bouity-Voubou, M., & DELVIN, E. E. (2010) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2009.12.005 · Cited by 76

Prenatal stress alters immune function in the offspring of rats

Klein, S. L., & Rager, D. R. (1995) · Developmental Psychobiology · doi:10.1002/dev.420280603 · Cited by 76

Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring

Camm, E. J., Martin‐Gronert, M. S., Wright, N., Hansell, J. A., Ozanne, S. E., & Giussani, D. A. (2010) · The FASEB Journal · doi:10.1096/fj.10-158188 · Cited by 75

Indices of oxidative stress in pregnancy with fetal growth restriction

Karowicz-Bilińska, A., Kędziora–Kornatowska, K., & Bartosz, G. (2007) · Free Radical Research · doi:10.1080/10715760701291647 · Cited by 75

Biomarkers of Oxidative Stress and Antioxidant Status in Children Born Small for Gestational Age: Evidence of Lipid Peroxidation

Franco, M. C. P., Kawamoto, E. M., Gorjão, R., Rastelli, V. M. F., Curi, R., Scavone, C., Sawaya, A. L., Fortes, Z. B., & Sesso, R. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180986d04 · Cited by 75

Effect of maternal low-protein diet and taurine on the vulnerability of adult Wistar rat islets to cytokines

Reusens, B., Goosse, K., Kalbe, L., Ahn, M., Tamarit‐Rodriguez, J., Remacle, C., Merezak, S., & Renard, A. (2004) · Diabetologia · doi:10.1007/s00125-004-1357-z · Cited by 72

Examination of Glucocorticoid Receptor α-Mediated Transcriptional Regulation of P-glycoprotein, CYP3A4, and CYP2C9 Genes in Placental Trophoblast Cell Lines

Pávek, P., Červený, L., Svecova, L., Brysch, M., Libra, A., Vrzal, R., Nachtigal, P., Štaud, F., Jitka Ulrichová, A., Fendrich, Z., et al. (2007) · Placenta · doi:10.1016/j.placenta.2007.05.001 · Cited by 71

Effects of maternal stress on anxiety levels, macrophage activity, and Ehrlich tumor growth

Neto, J. P., Massoco, C. D. O., & Fávare, R. C. (2001) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(01)00164-7 · Cited by 71

Norepinephrine causes epigenetic repression of PKCε gene in rodent hearts by activating Nox1‐dependent reactive oxygen species production

Xiong, F., Xiao, D., & Zhang, L. (2012) · The FASEB Journal · doi:10.1096/fj.11-199422 · Cited by 71

Foetal hypoxia increases cardiac AT2R expression and subsequent vulnerability to adult ischaemic injury

Qin, X. Y., Dasgupta, C., Chen, M., & Zhang, L. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq303 · Cited by 71

Emergence of insulin resistance in juvenile baboon offspring of mothers exposed to moderate maternal nutrient reduction

Choi, J., Li, C., McDonald, T. J., Comuzzie, A. G., Mattern, V. L., & Nathanielsz, P. W. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00051.2011 · Cited by 71

Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

Nyirenda, M., Carter, R., Tang, J. I.-S., de Vries, A., Schlumbohm, C., Hillier, S. G., Streit, F., Oellerich, M., Armstrong, V. W., Fuchs, E., et al. (2009) · Diabetes · doi:10.2337/db09-0873 · Cited by 70

Variation in placental type 2 11β-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight

Rogerson, F. M., Kayes, K. M., & White, P. C. (1997) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(97)04027-6 · Cited by 69

Flow-mediated vasodilation is impaired in adult rat offspring exposed to prenatal hypoxia

Morton, J. S., Rueda‐Clausen, C. F., & Davidge, S. T. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01174.2010 · Cited by 69

Programmed hypertension: kidney, brain or both?

Dodic, M., Moritz, K. M., Koukoulas, I., & Wintour, E. M. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00693-8 · Cited by 67

Leptin and its role in pregnancy and fetal development‒an overview

Reitman, M. L., Bi, S., Marcus‐Samuels, B., & Gavrilova, O. (2001) · Biochemical Society Transactions · doi:10.1042/0300-5127:0290068 · Cited by 67

The effect of tobacco exposure on the fetal hypothalamic-pituitary-adrenal axis

McDonald, S., Walker, M., Perkins, S., Beyene, J., Murphy, K., Gibb, W., & Ohlsson, A. (2006) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01089.x · Cited by 66

The human glucocorticoid receptor promoter upstream sequences contain binding sites for the ubiquitous transcription factor, Yin Yang 1

Breslin, M. B., & Vedeckis, W. V. (1998) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00138-1 · Cited by 65

A Protein-Restricted Diet during Pregnancy Alters in Vitro Insulin Secretion from Islets of Fetal Wistar Rats

Cherif, H., Reusens, B., Dahri, S., & Remacle, C. (2001) · Journal of Nutrition · doi:10.1093/jn/131.5.1555 · Cited by 65

Quantification and Glucocorticoid Regulation of Glucocorticoid Receptor Transcripts in Two Human Leukemic Cell Lines

Pedersen, K. B., & Vedeckis, W. V. (2003) · Biochemistry · doi:10.1021/bi034651u · Cited by 64

Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic‐pituitary‐adrenal axis and blood pressure adaptions to high‐fat diet

Michailidou, Z., Carter, R. N., Marshall, E., Sutherland, H. G. E., Brownstein, D. G., Owen, E., Cockett, K., Kelly, V., Ramage, L., Al‐Dujaili, E. A. S., et al. (2008) · The FASEB Journal · doi:10.1096/fj.08-111914 · Cited by 62

Early adversity and serotonin transporter genotype interact with hippocampal glucocorticoid receptor mRNA expression, corticosterone, and behavior in adult male rats

Belay, H., Burton, C. L., Lovic, V., Meaney, M. J., Sokolowski, M., & Fleming, A. S. (2011) · Behavioral Neuroscience · doi:10.1037/a0022891 · Cited by 61

The 11-ketosteroid 11-ketodexamethasone is a glucocorticoid receptor agonist

Rebuffat, A., Tam, S., Nawrocki, A. R., Baker, M. E., Frey, B. M., Frey, F. J., & Odermatt, A. (2004) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2003.11.027 · Cited by 60

Reactive oxygen species downregulate catalase expression via methylation of a CpG Island in the Oct-1 promoter

Quan, X., Lim, S., & Jung, G. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.09.035 · Cited by 60

Foetal nicotine exposure causes PKCε gene repression by promoter methylation in rat hearts

Lawrence, J., Chen, M., Xiong, F., Xiao, D., Zhang, H., Buchholz, J. N., & Zhang, L. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq270 · Cited by 60

Increased Oxidative Stress in Prepubertal Children Born Small for Gestational Age

Mohn, A., Chiavaroli, V., Cerruto, M., Blasetti, A., Giannini, C., Bucciarelli, T., & Chiarelli, F. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1344 · Cited by 59

Hypothalamic–pituitary–adrenal axis activity in adults who were prenatally exposed to the Dutch famine

de Rooij, S. R., Painter, R. C., Phillips, D. I. W., Osmond, C., Michels, R. P. J., Bossuyt, P. M., Bleker, O. P., & Roseboom, T. J. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02193 · Cited by 59

Maternal sensitivity moderates the impact of prenatal anxiety disorder on infant responses to the still-face procedure

Grant, K., McMahon, C. A., Reilly, N. M., & Austin, M. (2010) · Infant Behavior and Development · doi:10.1016/j.infbeh.2010.05.001 · Cited by 58

Dexamethasone Enhances Oxidative Stress-Induced Cell Death in Murine Neural Stem Cells

Mutsaers, H. A. M., & Tofighi, R. (2012) · Neurotoxicity Research · doi:10.1007/s12640-012-9308-9 · Cited by 57

Effect of Prenatal Stress on the Hormonal Response to Acute and Chronic Stress and on Immune Parameters in the Offspring

Llorente, E., Brito, M. L., Machado, P., & González, M. C. (2002) · Journal of Physiology and Biochemistry · doi:10.1007/bf03179851 · Cited by 56

Characterization of promoter 1B in the human glucocorticoid receptor gene

Nunez, B. S., & Vedeckis, W. V. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00676-1 · Cited by 56

Cortisol responses to psychological stress in adults after prenatal exposure to the Dutch famine

de Rooij, S. R., Painter, R. C., Phillips, D. I. W., Osmond, C., Tanck, M. W. T., Bossuyt, P. M., & Roseboom, T. J. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.09.007 · Cited by 56

Behavioral insights from mouse models of forebrain- and amygdala-specific glucocorticoid receptor genetic disruption

Arnett, M. G., Kolber, B. J., Boyle, M. P., & Muglia, L. J. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.11.011 · Cited by 53

Birthsize, gestational age and adrenal function in adult life: studies of dexamethasone suppression and ACTH1-24 stimulation

Kajantie, E., Eriksson, J., Barker, D., Forsén, T., Osmond, C., Wood, P., Andersson, S., Dunkel, L., & Phillips, D. I. W. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1490569 · Cited by 53

Developmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation

Rodriguez‐Trejo, A., Ortiz‐López, M. G., Zambrano, E., Granados‐Silvestre, M. D. L. Á., Méndez, C., Blondeau, B., Bréant, B., Nathanielsz, P. W., & Menjívar, M. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00619.2011 · Cited by 53

Glucocorticoid Receptor Gene Expression in the Embryonic Rat Brain

Kitraki, E., Alexis, Μ. N., Papalopoulou, M. A., & Stylianopoulou, F. (2008) · Neuroendocrinology · doi:10.1159/000126971 · Cited by 52

Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood

LANGDOWN, M. L., Holness, M. J., & Sugden, M. C. (2001) · Journal of Endocrinology · doi:10.1677/joe.0.1690011 · Cited by 51

The glucocorticoid receptor gene exon 1-F promoter is not methylated at the NGFI-A binding site in human hippocampus

Moser, D., Molitor, A. M., Kumsta, R., Tatschner, T., Riederer, P. F., & Meyer, J. (2007) · The World Journal of Biological Psychiatry · doi:10.1080/15622970701429862 · Cited by 50

Effects of prenatal maternal stress on the pituitary adrenocortical reactivity in guinea-pig pups.

Cadet, R., Pradier, P., Dalle, M., & Delost, P. (1986) · PubMed · Cited by 50

Demonstration of the intracellular localization and up-regulation of glucocorticoid receptor by in situ hybridization and immunocytochemistry.

Antakly, T., Thompson, E. B., & O'Donnell, D. (1989) · PubMed · Cited by 49

Leptin and its role in pregnancy and fetal development — an overview

Reitman, M. L., Bi, S., Marcus‐Samuels, B., & Gavrilova, O. (2001) · Biochemical Society Transactions · doi:10.1042/bst0290068 · Cited by 48

Maternal glucocorticoid deficit affects hypothalamic–pituitary–adrenal function and behavior of rat offspring

Wilcoxon, J. S., & Redei, E. E. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.11.006 · Cited by 47

Dexamethasone pre-treatment protects brain against hypoxic-ischemic injury partially through up-regulation of vascular endothelial growth factor A in neonatal rats

Feng, Y., Rhodes, P. G., & Bhatt, A. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.01.050 · Cited by 47

Postnatal ontogeny of hippocampal expression of the mineralocorticoid and glucocorticoid receptors in the common marmoset monkey

Pryce, C. R., Feldon, J., Fuchs, E., Knuesel, I., Oertle, T., Sengstag, C., Spengler, M., Weber, E., Weston, A. A., & Jongen‐Rêlo, A. L. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04003.x · Cited by 44

Cyclic AMP-Dependent Protein Kinase Modulation of the Glucocorticoid-lnduced Cytolytic Response in Murine T-Lymphoma Cells

Gruol, D. J., Rajah, F. M., & Bourgeois, S. (1989) · Molecular Endocrinology · doi:10.1210/mend-3-12-2119 · Cited by 43

A Conserved Molecular Mechanism Is Responsible for the Auto-Up-Regulation of Glucocorticoid Receptor Gene Promoters

Geng, C.-D., Schwartz, J. R., & Vedeckis, W. V. (2008) · Molecular Endocrinology · doi:10.1210/me.2008-0157 · Cited by 42

Impairment of Rat Fetal Beta-Cell Development by Maternal Exposure to Dexamethasone during Different Time-Windows

Dumortier, O., Theys, N., Ahn, M., Remacle, C., & Reusens, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025576 · Cited by 41

Alterations in stress responses of the hypothalamic-pituitary-adrenal axis in small for gestational age infants

Osterholm, E. A., Hostinar, C. E., & Gunnar, M. R. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.03.005 · Cited by 41

Three Mechanisms Are Involved in Glucocorticoid Receptor Autoregulation in a Human T-Lymphoblast Cell Line

Pedersen, K. B., Geng, C.-D., & Vedeckis, W. V. (2004) · Biochemistry · doi:10.1021/bi049458u · Cited by 40

Prenatal Cocaine Exposure and Infant Cortisol Reactivity

Eiden, R. D., Veira, Y., & Granger, D. A. (2009) · Child Development · doi:10.1111/j.1467-8624.2009.01277.x · Cited by 40

Multiple Promoters Exist in the Human GR Gene, One of Which Is Activated by Glucocorticoids

Breslin, M. B. (2001) · Molecular Endocrinology · doi:10.1210/me.15.8.1381 · Cited by 40

Differential Regulation and Function of 5′-Untranslated GR-Exon 1 Transcripts

Bockmühl, Y., Murgatroyd, C., Kuczynska, A., Adcock, I. M., Almeida, O. F. X., & Spengler, D. (2011) · Molecular Endocrinology · doi:10.1210/me.2010-0436 · Cited by 39

Maternal reactivity to fetal alloantigens is related to newborn immune responses and subsequent allergic disease

Prescott, S. L., Taylor, A. L., Roper, J. M., Wahdan, A. N., Noakes, P. S., Thornton, C. A., Dunstan, J. A., & Upham, J. W. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02171.x · Cited by 39

Steroid-Responsive Sequences in the Human Glucocorticoid Receptor Gene 1A Promoter

Geng, C.-D., & Vedeckis, W. V. (2004) · Molecular Endocrinology · doi:10.1210/me.2003-0157 · Cited by 39

Sexually dimorphic effects of maternal alcohol intake and adrenalectomy on left ventricular hypertrophy in rat offspring

Wilcoxon, J. S., Schwartz, J., Aird, F., & Redei, E. E. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00552.2002 · Cited by 39

Characterization of regional and gender differences in glucocorticoid receptors and lipoprotein lipase activity in human adipose tissue

Pedersen, S. B. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.78.6.1354 · Cited by 38

High Fat Programming of β-Cell Failure

Cerf, M. E. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-90-481-3271-3_5 · Cited by 37

Can the Behaviour Abnormalities Induced by Gestational Stress in Rats be Prevented or Reversed?

Weinstock, M. (2002) · Stress · doi:10.1080/1025389021000010503 · Cited by 37

Partial blockade of T-cell differentiation during ontogeny and marked alterations of the thymic microenvironment in transgenic mice with impaired glucocorticoid receptor function

Sacedón, R., Vicente, Á., Varas, A., Morale, M. C., Barden, N., Marchetti, B., & Zapata, A. G. (1999) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(99)00091-0 · Cited by 37

Effects of early- and late-gestational maternal stress and synthetic glucocorticoid on development of the fetal hypothalamus–pituitary–adrenal axis in sheep

Rakers, F., Frauendorf, V., Rupprecht, S., Schiffner, R., Bischoff, S. J., Kiehntopf, M., Reinhold, P., Witte, O. W., Schubert, H., & Schwab, M. G. (2012) · Stress · doi:10.3109/10253890.2012.686541 · Cited by 37

Human glucocorticoid receptor gene promotor—homologous down regulation

Govindan, M. V., Pothier, F., Leclerc, S., Palaniswami, R., & Xie, B. (1991) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(91)90197-d · Cited by 36

Fetal undernutrition induces overexpression of CRH mRNA and CRH protein in hypothalamus and increases CRH and corticosterone in plasma during postnatal life in the rat

Núñez, H., Ruíz, S., Soto‐Moyano, R., Navarrete, M., Valladares, L., White, A., & Pérez, H. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.10.014 · Cited by 36

Chronic Hypoxia Decreases Endothelial Nitric Oxide Synthease Protein Expression in Fetal Guinea Pig Hearts

Thompson, L. P., & Dong, Y. (2005) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2005.04.011 · Cited by 34

Is programming of glucocorticoid receptor expression by prenatal dexamethasone in the rat secondary to metabolic derangement in adulthood?

Cleasby, M. E., Livingstone, D., Nyirenda, M., Seckl, J. R., & Walker, B. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1480129 · Cited by 34

In Utero Oxidative Stress Epigenetically Programs Antioxidant Defense Capacity and Adulthood Diseases

Strakovsky, R. S., & Pan, Y. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4372 · Cited by 33

Perinatal nutritional programming of health and metabolic adult disease

Vieau, D. (2011) · World Journal of Diabetes · doi:10.4239/wjd.v2.i9.133 · Cited by 33

Evidence That Prenatal Programming of Hypertension by Dietary Protein Deprivation Is Mediated by Fetal Glucocorticoid Exposure

Habib, S., Gattineni, J., Twombley, K. E., & Baum, M. G. (2010) · American Journal of Hypertension · doi:10.1038/ajh.2010.177 · Cited by 32

Chronic fetal hypoxia produces selective brain injury associated with altered nitric oxide synthases

Dong, Y., Yu, Z., Sun, Y., Zhou, H., Stites, J., Newell, K., & Weiner, C. P. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.11.032 · Cited by 32

Effects of Betamethasone Treatment on Central Myelination in Fetal Sheep: An Electron Microscopical Study

Raschke, C., Schmidt, S., Schwab, M., & Jirikowski, G. F. (2008) · Anatomia, Histologia, Embryologia. Journal of Veterinary Medicine Series C · doi:10.1111/j.1439-0264.2007.00807.x · Cited by 29

In utero glucocorticoid exposure reduces fetal skeletal muscle mass in rats independent of effects on maternal nutrition

Gokulakrishnan, G., Estrada, I. J., Sosa, H. A., & Fiorotto, M. L. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00466.2011 · Cited by 29

Glucocorticoids dexamethasone and hydrocortisone inhibit proliferation and accelerate maturation of chicken cerebellar granule neurons

Aden, P. K., Paulsen, R. E., Mæhlen, J., Løberg, E. M., Goverud, I. L., Liestøl, K., & Lømo, J. (2011) · Brain Research · doi:10.1016/j.brainres.2011.08.053 · Cited by 28

Expression of glucocorticoid receptors in the hippocampal region of the rat brain during postnatal development

Galeeva, A., Ordyan, N., Пивина, С. Г., & Pelto‐Huikko, M. (2006) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2006.01.004 · Cited by 28

Influence of placental 11β-hydroxysteroid dehydrogenase (11β-HSD) inhibition on glucose metabolism and 11β-HSD regulation in adult offspring of rats

Saegusa, H., Nakagawa, Y., Liu, Y., & Ohzeki, T. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90249-4 · Cited by 28

Regulation of glucocorticoid receptor mRNA and heat shock protein 70 mRNA in the developing sheep brain

Andrews, M. H., & Matthews, S. G. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02735-9 · Cited by 28

Differential timing for programming of glucose homoeostasis, sensitivity to insulin and blood pressure by in utero exposure to dexamethasone in sheep

Gatford, K. L., Wintour, E. M., BLASIO, M. J. D., et al. (2000) · Clinical Science · doi:10.1042/cs19990229 · Cited by 28

Differential Expression of Endothelial Nitric Oxide Synthase in Coronary and Cardiac Tissue in Hypoxic Fetal Guinea Pig Hearts

Dong, Y., & Thompson, L. P. (2006) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2006.06.005 · Cited by 27

Endothelial Superoxide Production Is Altered in Sheep Programmed by Early Gestation Dexamethasone Exposure

Roghair, R. D., Miller, F. J., SCHOLZ, T. D., Lamb, F. S., & Segar, J. L. (2007) · Neonatology · doi:10.1159/000105521 · Cited by 24

Expression of glucocorticoid and mineralocorticoid receptors in hippocampus of rats exposed to various modes of hypobaric hypoxia: Putative role in hypoxic preconditioning

Rybnikova, E. A., Glushchenko, T., Churilova, A. V., Пивина, С. Г., & Samoilov, M. O. (2011) · Brain Research · doi:10.1016/j.brainres.2011.01.005 · Cited by 22

Human Glucocorticoid Receptor α Transcript Splice Variants with Exon 2 Deletions: Evidence for Tissue- and Cell Type-Specific Functions

Geng, C.-D., Pedersen, K. B., Nunez, B. S., & Vedeckis, W. V. (2005) · Biochemistry · doi:10.1021/bi047485e · Cited by 21

Glucose tolerance in adults after prenatal exposure to famine

Kahn, H. S. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04911-4 · Cited by 15

Pulmonary phospholipid saturation increases with glucocorticoid receptor mRNAs in late gestation but not due to labor in the fetal rhesus monkey

Zhang, Q., Wu, W., Ma, X., Nathanielsz, P. W., & Brenna, J. T. (1997) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(97)90550-0 · Cited by 4

A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications

Godoy, L. D., Rossignoli, M. T., Delfino-Pereira, P., Garcia‐Cairasco, N., & Umeoka, E. H. D. L. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00127 · Cited by 991

Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: a randomised, double-blind, placebo-controlled study

Lew, L.-C., Hor, Y.-Y., Yusoff, N. A. A., Choi, S.-B., Yusoff, M. S. B., Roslan, N. S., Ahmad, A., Mohammad, J. A. M., Abdullah, M. F. I. L., Zakaria, N., et al. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2018.09.010 · Cited by 272

Gestational Hypoxia and Developmental Plasticity

Ducsay, C. A., Goyal, R., Pearce, W. J., Wilson, S. M., Hu, X., & Zhang, L. (2018) · Physiological Reviews · doi:10.1152/physrev.00043.2017 · Cited by 208

Developmental origins of the human hypothalamic-pituitary-adrenal axis

Howland, M. A., Sandman, C. A., & Glynn, L. M. (2017) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2017.1356222 · Cited by 192

Glucocorticoid receptor gene (NR3C1) methylation following stressful events between birth and adolescence. The TRAILS study

van der Knaap, L. J., Riese, H., Hudziak, J. J., Verbiest, M. M. P. J., Verhulst, F. C., Oldehinkel, A. J., & van Oort, F. V. A. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.22 · Cited by 165

Maternal influences on epigenetic programming of the developing hypothalamic‐pituitary‐adrenal axis

Grace, C. E., Kim, S., & Rogers, J. M. (2011) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20824 · Cited by 34

Developmental origins of the human hypothalamic-pituitary-adrenal axis

Howland, M. A., Sandman, C. A., & Glynn, L. M. (2017) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2017.1356222 · Cited by 192

Development and Programming of the Hypothalamus-Pituitary-Adrenal Axis

Wood, C. E. (2013) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31829e5b15 · Cited by 24

The epigenetics of the hypothalamic‐pituitary‐adrenal axis in fetal development

Montenegro, Y. H. A., Nascimento, D. D. Q., Assis, T. D. O., & Lopes, S. S. D. S. (2019) · Annals of Human Genetics · doi:10.1111/ahg.12306 · Cited by 17

Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms

Matthews, S. G., & McGowan, P. O. (2019) · Journal of Endocrinology · doi:10.1530/joe-19-0057 · Cited by 85