The prescription or proscription of exercise in endometrial cancer care
Open accessAbstract
Objective To determine the proportion of endometrial cancer patients who can be safely prescribed community/home based unsupervised exercise. A better understanding of the physical dysfunction secondary to comorbidities among endometrial cancer patients would assist clinicians in delineating which patients to send to medically-based supervised rehabilitation versus a community/home based unsupervised exercise program.Methods A literature review identified health issues which could impede patients from successfully completing an unsupervised exercise program after a cancer diagnosis. The charts of 479 endometrial cancer patients treated between 2006 and 2010 were reviewed to determine the health status at the time of diagnosis and the type and percentage of health-issues that could preclude an unsupervised exercise program in this population. Univariable modeling and multivariable modeling were used to evaluate the association of demographic, cancer-related characteristics and clinical variables with ability to participate in unsupervised exercise.Results We determined that 14.2% of endometrial cancer patients were able to exercise without supervision based on their health status at the time of diagnosis. After excluding common comorbidities (hypertension, diabetes and morbid obesity) from the identified health-issues, the proportion increased to 20.5%. Older at diagnosis (P=0.007) and higher BMI (P<0.001) are more likely to exclude patients from community/home based unsupervised exercise program.Conclusions Only 14.2% to 20.5% of endometrial cancer patients were deemed able to exercise without supervision based on their health status at diagnosis. Our data suggest that approximately 80% of endometrial cancer patients would benefit from a referral to a medically-based supervised exercise program.
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Older age at diagnosis predicted the need for exercise supervision in survivors across all four tumor sites.
“Older age at diagnosis predicted the need for exercise supervision in survivors who had all 4 tumor sites.”
From Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer (2019) · cites this paper as [71]
Endometrial cancer survivors' need for a supervised exercise program at 6 months after active cancer therapy is 80%.
“The proportion of endometrial, colorectal, head and neck, and breast cancer survivors who would need a supervised program were 80%, 58%, 60%, and 35%, respectively.53,70-73”
From Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer (2019) · cites this paper as [71]
Head and neck cancer survivors' need for a supervised exercise program at 6 months after active cancer therapy is 60%.
“The proportion of endometrial, colorectal, head and neck, and breast cancer survivors who would need a supervised program were 80%, 58%, 60%, and 35%, respectively.53,70-73”
From Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer (2019) · cites this paper as [71]
Breast cancer survivors' need for a supervised exercise program at 6 months after active cancer therapy is 35%.
“The proportion of endometrial, colorectal, head and neck, and breast cancer survivors who would need a supervised program were 80%, 58%, 60%, and 35%, respectively.53,70-73”
From Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer (2019) · cites this paper as [71]
Colorectal cancer survivors' need for a supervised exercise program at 6 months after active cancer therapy is 58%.
“The proportion of endometrial, colorectal, head and neck, and breast cancer survivors who would need a supervised program were 80%, 58%, 60%, and 35%, respectively.53,70-73”
From Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer (2019) · cites this paper as [71]
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Cites
Health benefits of physical activity: the evidence
Warburton, D. E. R. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.051351 · Cited by 8,007 · see citing works
Physical Activity and Public Health in Older Adults
Nelson, M. E., Rejeski, W. J., Blair, S. N., Duncan, P. W., Judge, J. O., King, A. C., Macera, C. A., & Castaneda‐Sceppa, C. (2007) · Circulation · doi:10.1161/circulationaha.107.185650 · Cited by 2,991 · see citing works
Nutrition and physical activity guidelines for cancer survivors
Rock, C. L., Doyle, C., Demark‐Wahnefried, W., Meyerhardt, J., Courneya, K. S., Schwartz, A. L., Bandera, E. V., Hamilton, K. K., Grant, B., McCullough, M., et al. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21142 · Cited by 1,995 · see citing works
Speck, R. M., Courneya, K. S., Mâsse, L. C., Duval, S., & Schmitz, K. H. (2010) · Journal of Cancer Survivorship · doi:10.1007/s11764-009-0110-5 · Cited by 1,352 · see citing works
Self-citationFletcher, G. F., Balady, G., Blair, S. N., Blumenthal, J., Caspersen, C., Chaitman, B., Epstein, S., Froelicher, E. S. S., Froelicher, V. F., Pina, I. L., et al. (1996) · Circulation · doi:10.1161/01.cir.94.4.857 · Cited by 1,319 · see citing works
Courneya, K. S., SEGAL, R. J., Mackey, J. R., Gelmon, K. A., Reid, R. D., Friedenreich, C. M., Ladha, A. B., Proulx, C., Vallance, J. K., Lane, K. N., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.08.2024 · Cited by 1,182 · see citing works
Cardiovascular disease is the leading cause of death among endometrial cancer patients
Ward, K. K., Shah, N. R., Saenz, C. C., McHale, M. T., Alvarez, E. A., & Plaxe, S. C. (2012) · Gynecologic Oncology · doi:10.1016/j.ygyno.2012.04.013 · Cited by 259 · see citing works
Furberg, A., & Thune, I. (2003) · International Journal of Cancer · doi:10.1002/ijc.10974 · Cited by 224 · see citing works
Long‐term psychosocial adjustment of older vs younger survivors of breast and endometrial cancer
Kornblith, A. B., Powell, M. E., Regan, M. M., Bennett, S., Krasner, C. N., Moy, B., Younger, J., Goodman, A., Berkowitz, R. S., & Winer, E. P. (2007) · Psycho-Oncology · doi:10.1002/pon.1146 · Cited by 215 · see citing works
Courneya, K. S., Karvinen, K. H., Campbell, K. L., Pearcey, R. G., Dundas, G. S., Capstick, V. A., & Tonkin, K. S. (2005) · Gynecologic Oncology · doi:10.1016/j.ygyno.2005.01.007 · Cited by 207 · see citing works
Lachance, J. A., Everett, E. N., Greer, B. E., Mandel, L. S., Swisher, E. M., Tamimi, H. K., & Goff, B. A. (2006) · Gynecologic Oncology · doi:10.1016/j.ygyno.2005.11.009 · Cited by 139 · see citing works
von Gruenigen, V. E., Courneya, K. S., Gibbons, H. E., Kavanagh, M. B., Waggoner, S. E., & Lerner, E. (2008) · Gynecologic Oncology · doi:10.1016/j.ygyno.2007.12.026 · Cited by 138 · see citing works
O’Connor, F. G., Casa, D. J., Bergeron, M. F., Carter, R., Deuster, P. A., Heled, Y., Kark, J. A., Leon, L. R., McDermott, B. P., O'Brien, K., et al. (2010) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e3181f1d183 · Cited by 119 · see citing works
New NCCN Guidelines® for Survivorship Care
Ligibel, J. A., & Denlinger, C. S. (2013) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2013.0191 · Cited by 107 · see citing works
Basen-Engquist, K. M., Scruggs, S., Jhingran, A., Bodurka, D. C., Lu, K. H., Ramondetta, L. M., Hughes, D. C., & Taylor, C. C. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.10.010 · Cited by 95 · see citing works
Gynecological cancer survivors’ health behaviors and their associations with quality of life
Beesley, V. L., Eakin, E., Janda, M., & Battistutta, D. (2008) · Cancer Causes & Control · doi:10.1007/s10552-008-9140-y · Cited by 81 · see citing works
Quality of life in endometrial cancer survivors
Li, C., Samsioe, G., & Iosif, C. S. (1999) · Maturitas · doi:10.1016/s0378-5122(98)00106-6 · Cited by 55 · see citing works
Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment
Prue, G., Allen, J. M., Gracey, J. H., Rankin, J. P., & Cramp, F. L. (2009) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2009.06.011 · Cited by 53 · see citing works
Brown, J. C., & Schmitz, K. H. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2014.57.7395 · Cited by 50 · see citing works
Self-citationJones, L. W. (2011) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h11-043 · Cited by 49 · see citing works
Comorbidities and endometrial cancer survival in Hispanics and non-Hispanic whites
Cook, L. S., Nelson, H. E., Cockburn, M., Olson, S. H., Muller, C. Y., & Wiggins, C. L. (2012) · Cancer Causes & Control · doi:10.1007/s10552-012-0090-z · Cited by 43 · see citing works
Objectively measured physical activity among US cancer survivors: considerations by weight status
Loprinzi, P. D., Lee, H. J., & Cardinal, B. J. (2013) · Journal of Cancer Survivorship · doi:10.1007/s11764-013-0293-7 · Cited by 42 · see citing works
The Prescription or Proscription of Exercise in Colorectal Cancer Care
Brown, J. C., & Schmitz, K. H. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000355 · Cited by 41 · see citing works
Self-citationAre long-term cancer survivors and physicians discussing health promotion and healthy behaviors?
Kenzik, K. M., Pisu, M., Fouad, M. N., & Martin, M. Y. (2015) · Journal of Cancer Survivorship · doi:10.1007/s11764-015-0473-8 · Cited by 38 · see citing works
Endometrial cancer survivors' assessment of the benefits of exercise
Lukowski, J. K., Gil, K. M., Jenison, E. L., Hopkins, M. P., & Basen-Engquist, K. M. (2011) · Gynecologic Oncology · doi:10.1016/j.ygyno.2011.11.002 · Cited by 16 · see citing works
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Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer
Schmitz, K. H., Campbell, A. M., Stuiver, M. M., Pinto, B. M., Schwartz, A. L., Morris, G. S., Ligibel, J. A., Cheville, A., Galvão, D. A., Alfano, C. M., et al. (2019) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21579 · Cited by 789 · see citing works
Self-citationWeight management and physical activity throughout the cancer care continuum
Demark‐Wahnefried, W., Schmitz, K. H., Alfano, C. M., Bail, J. R., Goodwin, P. J., Thomson, C. A., Bradley, D. W., Courneya, K. S., Befort, C. A., Denlinger, C. S., et al. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21441 · Cited by 172 · see citing works
Self-citationAlfano, C. M., Zucker, D. S., Pergolotti, M., Ness, K. K., Jones, L. W., Price, N. D., Schmitz, K. H., & Ligibel, J. A. (2017) · Current Physical Medicine and Rehabilitation Reports · doi:10.1007/s40141-017-0145-x · Cited by 38 · see citing works
Self-citationPapatla, K., Huang, M. S., & Slomovitz, B. M. (2016) · Annals of Oncology · doi:10.1093/annonc/mdw310 · Cited by 32 · see citing works
Lucas, A. R., Focht, B. C., Cohn, D. E., Buckworth, J., & Klatt, M. D. (2016) · Integrative Cancer Therapies · doi:10.1177/1534735416668257 · Cited by 22 · see citing works
Effect of Physical Activity on Quality of Life as Perceived by Endometrial Cancer Survivors
Babatunde, O. A., Adams, S. A., Orekoya, O., Basen-Engquist, K. M., & Steck, S. E. (2016) · International Journal of Gynecological Cancer · doi:10.1097/igc.0000000000000821 · Cited by 20 · see citing works
Gray, L., Sindall, P., & Pearson, S. J. (2023) · Disability and Rehabilitation · doi:10.1080/09638288.2023.2226408 · Cited by 18 · see citing works
Association between Body Mass Index and Physical Function among Endometrial Cancer Survivors
Zhang, X., Brown, J. C., & Schmitz, K. H. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160954 · Cited by 14 · see citing works
Self-citationHutchison, N. A., Deval, N., Rabusch, S., Rich, H., Kelley, T., Flinn, N. A., & Banerji, N. (2019) · PM&R · doi:10.1002/pmrj.12128 · Cited by 12 · see citing works
Bauml, J., Kim, J., Zhang, X., Aggarwal, C., Cohen, R. B., & Schmitz, K. (2017) · Journal of Cancer Survivorship · doi:10.1007/s11764-017-0604-5 · Cited by 10 · see citing works
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Igwebuike, L. T., Zhang, X., Brown, J. C., & Schmitz, K. H. (2018) · Supportive Care in Cancer · doi:10.1007/s00520-017-4020-1 · Cited by 8 · see citing works
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Mayer, A., & Cibula, D. (2024) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2024.108739 · Cited by 6 · see citing works
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Jiang, M., Chen, Y., & Shen, B. (2022) · Springer eBooks · doi:10.1007/978-981-16-9162-1_9 · Cited by 4 · see citing works
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Basen-Engquist, K. M., & Parker, N. H. (2020) · Springer eBooks · doi:10.1007/978-3-030-42011-6_18 · Cited by 2 · see citing works
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- Authors
- Zhang, X., Haggerty, A. F., Brown, J. C., Giuntoli, R., Lin, L., Simpkins, F., Dean, L. T., Ko, E., Morgan, M. A., & Schmitz, K. H.
- Affiliations
- University of Pennsylvania Health System (US)
- University of Pennsylvania (US)
- Corresponding author
- Schmitz, Kathryn H.
- ORCID
- Venue
- Gynecologic Oncology
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 139
- Issue
- 1
- Pages
- 155-159
- ISSN
- 0090-8258 (ISSN-L)
- PMC
- PMC4915365
- OpenAlex
- W2168555886
- Cited by
- 18
- References
- 26
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2017: 4 · 2016: 4
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Gynecologic Oncology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5k01ca184288-06, 7u54ca155850-06)
- National Cancer Institute (U54-CA155850, K01-CA184288)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
- Keywords
- endometrial cancer, unsupervised exercise, home-based exercise, supervised exercise, exercise prescription, comorbidities, physical dysfunction, body mass index, age, hypertension, diabetes mellitus, morbid obesity, cancer rehabilitation
- MeSH terms
- Adult, Aged, Aged, 80 and over, Exercise Therapy, Female, Humans, Middle Aged, Retrospective Studies, Endometrial Neoplasms
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