The DOI matches its Crossref record; 219 of the 219 references it cites were found in a registry or an index.
Sex differences in anxiety disorders: Interactions between fear, stress, and gonadal hormones
Open accessAbstract
Women are more vulnerable to stress- and fear-based disorders, such as anxiety and post-traumatic stress disorder. Despite the growing literature on this topic, the neural basis of these sex differences remains unclear, and the findings appear inconsistent. The neurobiological mechanisms of fear and stress in learning and memory processes have been extensively studied, and the crosstalk between these systems is beginning to explain the disproportionate incidence and differences in symptomatology and remission within these psychopathologies. In this review, we discuss the intersect between stress and fear mechanisms and their modulation by gonadal hormones and discuss the relevance of this information to sex differences in anxiety and fear-based disorders. Understanding these converging influences is imperative to the development of more effective, individualized treatments that take sex and hormones into account.
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Citations
Cites
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BackgroundStress signalling pathways that impair prefrontal cortex structure and function
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Cited by
Craske, M. G., Stein, M. B., Eley, T. C., Milad, M. R., Holmes, A., Rapee, R. M., & Wittchen, H.-U. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.24 · Cited by 652
The role of inflammation and the gut microbiome in depression and anxiety
Peirce, J. M., & Alviña, K. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24476 · Cited by 466
Investigating the psychological impact of COVID-19 among healthcare workers: a meta-analysis
Batra, K., Singh, T. P., Sharma, M., Batra, R., & Schvaneveldt, N. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17239096 · Cited by 342
Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats.
Knight, P., Chellian, R., Wilson, R., Behnood-Rod, A., Panunzio, S., & Bruijnzeel, A. W. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173168 · Cited by 252
The neurobiological basis of sex differences in learned fear and its inhibition
Day, H. L. L., & Stevenson, C. W. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14602 · Cited by 114
Metadata
- Authors
- Maeng, L. Y., & Milad, M. R.
- Venue
- Hormones and Behavior
- Publisher
- Elsevier BV
- Published
- 2015-11
- Volume
- 76
- Pages
- 106-117
- ISSN
- 0018-506X (ISSN-L)
- OpenAlex
- W2044100668
- Cited by
- 375
- References
- 219
- FWCI
- 11.62
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.