The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Acute Respiratory Distress Syndrome
Ware, L. B., & Matthay, M. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421806 · Cited by 4,666
Postinjury Multiple Organ Failure: A Bimodal Phenomenon
Moore, F. A., Sauaia, A., Moore, E. E., Haenel, J. B., Burch, J. M., & Lezotte, D. C. (1996) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-199604000-00001 · Cited by 491
Research works printed but not linked: 37
- Whittington, 1998, Liver transplantation for the treatment of urea cycle disorders, J. Inher. Metab. Dis., 21, 112, 10.1023/A:1005317909946 · DOI
- Morsy, 1993, Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes, J. Clin. Invest., 92, 1580, 10.1172/JCI116739 · doi:10.1172/jci116739
- Stratford-Perricaudet, 1990, Evaluation of the transfer and expression in mice of an enzyme encoding gene using a human adenovirus vector, Human Gene Ther., 1, 241, 10.1089/hum.1990.1.3-241 · DOI · Paper page
- Morsy, 1996, Patient selection may affect gene therapy success: dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes, J. Clin. Invest., 97, 826, 10.1172/JCI118482 · DOI
- Ye, 1996, Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectors, J. Biol. Chem., 271, 3639, 10.1074/jbc.271.7.3639 · DOI
- Yang, 1994, Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy, Proc. Natl. Acad. Sci. USA, 91, 4407, 10.1073/pnas.91.10.4407 · DOI · Paper page
- Ye, 1997, Adenovirus-mediated in vivo gene transfer rapidly protects ornithine transcarbamylase-deficient mice from an ammonium challenge, Pediatr. Res., 41, 527, 10.1203/00006450-199704000-00012 · DOI
- Nunes, 1999, Gene transfer into the liver of non-human primates with E1-deleted recombinant adenoviral vectors: safety of readministration, Hum. Gene Ther., 10, 2515, 10.1089/10430349950016852 · DOI
- Gao, 1996, Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy, J. Virol., 70, 8934, 10.1128/JVI.70.12.8934-8943.1996 · DOI · Paper page
- Christ, 2000, Modulation of the inflammatory properties and hepatoxicity of recombinant adenovirus vectors by the viral E4 gene products, Hum. Gene Ther., 11, 415, 10.1089/10430340050015888 · DOI
- Dedieu, 1997, Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenovirus, J. Virol., 71, 4626, 10.1128/JVI.71.6.4626-4637.1997 · DOI · Paper page
- Wang, 1997, Persistent transgene expression in mouse liver following in vivo gene transfer with a ΔE1/ΔE4 adenovirus vector, Gene Ther., 4, 393, 10.1038/sj.gt.3300404 · doi:10.1038/sj.gt.3300404
- Ye, 1998, Evaluating the potential of germ line transmission after intravenous administration of recombinant adenovirus in the C3H mouse, Hum. Gene Ther., 9, 2135, 10.1089/hum.1998.9.14-2135 · doi:10.1089/hum.1998.9.14-2135
- Raper, 1998, Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1–E4 deleted recombinant adenoviruses, Hum. Gene Ther., 9, 671, 10.1089/hum.1998.9.5-671 · DOI
- Reid, 2001, Intra-arterial administration of a replication-selective adenovirus (dl 1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial, Gene Ther., 8, 1518, 10.1038/sj.gt.3301512 · DOI · Paper page
- Raper, 2002, A pilot study of in vivo liver directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency, Hum. Gene Ther., 13, 163, 10.1089/10430340152712719 · DOI · Paper page
- Maddalena, 1988, Mosaicism for an intragenic deletion in a boy with mild ornithine transcarbamylase deficiency, N. Engl. J. Med., 319, 999, 10.1056/NEJM198810133191507 · DOI
- Batshaw, 1984, Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis, N. Engl. J. Med., 310, 1630, 10.1056/NEJM198406213102503 · DOI
- Sauaia, 1994, Early predictors of postinjury multiple organ failure, Arch. Surg., 129, 39, 10.1001/archsurg.1994.01420250051006 · DOI · Paper page
- Faist, 1996, Update on the mechanisms of immune suppression of injury and immune modulation, World J. Surg., 20, 454, 10.1007/s002689900071 · DOI · Paper page
- Biffl, 1996, Interleukin-6 in the injured patient: marker of injury or mediator of inflammation?, Ann. Surg., 224, 647, 10.1097/00000658-199611000-00009 · DOI · Paper page
- Headley, 1997, Infections and the inflammatory response in acute respiratory distress syndrome, Chest, 111, 1306, 10.1378/chest.111.5.1306 · DOI · Paper page
- van der Poll, 1990, Activation of coagulation after administration of tumor necrosis factor to normal subjects, N. Engl. J. Med., 322, 1622, 10.1056/NEJM199006073222302 · DOI · Paper page
- Levi, 1997, The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia, Eur. J. Clin. Invest., 27, 3, 10.1046/j.1365-2362.1997.570614.x · DOI · Paper page
- Zhang, 1998, Inhibition of tumor necrosis factor α decreases inflammation and prolongs adenovirus gene expression in lung and liver, Hum. Gene Ther., 9, 1875, 10.1089/hum.1998.9.13-1875 · DOI
- Zhang, 2001, Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages, Mol. Ther., 3, 697, 10.1006/mthe.2001.0329 · DOI · Paper page
- Schnell, 2001, Activation of innate immunity of nonhuman primates following intraportal administration of adenoviral vectors, Mol. Ther., 3, 708, 10.1006/mthe.2001.0330 · DOI · Paper page
- Bone, 1991, The pathogenesis of sepsis, Ann. Intern. Med., 115, 457, 10.7326/0003-4819-115-6-457 · DOI · Paper page
- Partrick, 1999, Release of anti-inflammatory mediators after major torso trauma correlates with the development of postinjury multiple organ failure, Am. J. Surg., 178, 564, 10.1016/S0002-9610(99)00240-8 · DOI
- Schroder, 1995, Pattern of soluble TNF receptors I and II in sepsis, Infection, 23, 143, 10.1007/BF01793854 · DOI
- Yang, 1994, MHC Class I restricted cytotoxic lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses, Immunity, 1, 433, 10.1016/1074-7613(94)90074-4 · DOI · Paper page
- Zsengeller, 1995, Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune deficient (nu/nu) mice, Hum. Gene Ther., 6, 457, 10.1089/hum.1995.6.4-457 · DOI
- Yang, 1995, Cellular and humoral immune responses to antigens create barriers to lung directed gene therapy with recombinant adenoviruses, J. Virol., 69, 2004, 10.1128/JVI.69.4.2004-2015.1995 · DOI · Paper page
- Tripathy, 1996, Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors, Nat. Med., 2, 545, 10.1038/nm0596-545 · DOI · Paper page
- Yao, 1996, Adenovirus-mediated transfer of human factor IX gene in immunodeficient and normal mice: evidence for prolonged stability and activity of the transgene in liver, Viral Immunol., 9, 141, 10.1089/vim.1996.9.141 · doi:10.1089/vim.1996.9.141
- Morral, 1997, Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors, Hum. Gene Ther., 8, 1275, 10.1089/hum.1997.8.10-1275 · DOI
- Tao, 2001, Sequestration of adenorival vector by Kupffer cells leads to a non-linear dose response of transduction in liver, Mol. Ther., 3, 28, 10.1006/mthe.2000.0227 · DOI · Paper page
Cited by
Karikó, K., Muramatsu, H., Welsh, F. A., Ludwig, J., Kato, H., Akira, S., & Weissman, D. (2008) · Molecular Therapy · doi:10.1038/mt.2008.200 · Cited by 1,930
Viral vector platforms within the gene therapy landscape
Bulcha, J. T., Wang, Y., Ma, H., Tai, P. W. L., & Gao, G. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00487-6 · Cited by 1,404
Self-citationImmune responses to AAV vectors: overcoming barriers to successful gene therapy
Mingozzi, F., & High, K. A. (2013) · Blood · doi:10.1182/blood-2013-01-306647 · Cited by 955
Karikó, K., Muramatsu, H., Ludwig, J., & Weissman, D. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr695 · Cited by 898
Therapeutic in vivo gene transfer for genetic disease using AAV: Progress and challenges
Mingozzi, F., & High, K. A. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2988 · Cited by 893
Metadata
- Authors
- Raper, S. E., Chirmule, N., Lee, F. S., Wivel, N. A., Bagg, A., Gao, G.-P., Wilson, J. M., & Batshaw, M. L.
- Venue
- Molecular Genetics and Metabolism
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 80
- Issue
- 1-2
- Pages
- 148-158
- ISSN
- 1096-7192 (ISSN-L)
- OpenAlex
- W2093424805
- Cited by
- 1,498
- References
- 2
- FWCI
- 33.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. https://app.cochat.ai/papers/10.1016/j.ymgme.2003.08.016
- The paper
- Raper, S. E., Chirmule, N., Lee, F. S., Wivel, N. A., Bagg, A., Gao, G.-P., Wilson, J. M., & Batshaw, M. L. (2003). Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Molecular Genetics and Metabolism. https://doi.org/10.1016/j.ymgme.2003.08.016
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.